• Journal of Microbiology and Biotechnology
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• v.30 no.8
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• pp.1252-1260
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• 2020

(R)-2-(4-hydroxyphenoxy)propionic acid (HPOPA) is a key intermediate for the preparation of aryloxyphenoxypropionic acid herbicides (R-isomer). In order to improve the HPOPA production from the substrate (R)-2-phenoxypropionic acid (POPA) with Beauveria bassiana CCN-A7, static cultivation and H₂O₂ addition were attempted and found to be conducive to the task at hand. This is the first report on HPOPA production under static cultivation and reactive oxygen species (ROS) induction. On this premise, the cultivation conditions and fermentation medium compositions were optimized. As a result, the optimal carbon source, organic nitrogen source, and inorganic nitrogen source were determined to be glucose, peptone, and ammonium sulfate, respectively. The optimal inoculum size and fermentation temperature were 13.3% and 28℃, respectively. The significant factors including glucose, peptone, and H₂O₂, identified based on Plackett-Burman design, were further optimized through Central Composite Design (CCD). The optimal concentrations were as follows: glucose 38.81 g/l, peptone 7.28 g/l, and H₂O₂ 1.08 g/l/100 ml. Under the optimized conditions, HPOPA titer was improved from 9.60 g/l to 19.53 g/l, representing an increase of 2.03-fold. The results obtained in this work will provide novel strategies for improving the biosynthesis of hydroxy aromatics.

• Journal of the Korean Society of Hazard Mitigation
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• v.10 no.6
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• pp.17-25
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• 2010

This paper studied on stability of the U-channel segmental concrete bridge under vehicle-impact loads. The U-channel bridge has advantages in that it reduces an additional dead load and the edge beams role as a barrier. But it has a dangerous factor which collapses the bridge structure when the edge beams are ruptured. Therefore, it is necessary to verify behaviors of the bridge system under vehicle-impact loads. Static and dynamic vehicle impact simulations were carried out on the basis of AASHTO LRFD design specifications. In case of the static analysis, equivalent static loads specified in the AASHTO codes are loaded on the edge beams and in case of the dynamic analysis, FEM vehicle models are modeled by applying the dynamic test specifications of AASHTO codes. As a result, it is shown that U-channel bridge system has sufficient safety against static and dynamic impact loads specified in the AASHTO LRFD design specifications.

• The Journal of Advanced Prosthodontics
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• v.8 no.5
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• pp.388-395
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• 2016

PURPOSE. The purpose of this study was to evaluate the resistance to deformation under static overloading by measuring yield and fracture strength, and to analyze the failure characteristics of implant assemblies made of different titanium grades and connections. MATERIALS AND METHODS. Six groups of implant assemblies were fabricated according to ISO 14801 (n=10). These consisted of the combinations of 3 platform connections (external, internal, and morse tapered) and 2 materials (titanium grade 2 and titanium grade 4). Yield strength and fracture strength were evaluated with a computer-controlled Universal Testing Machine, and failed implant assemblies were classified and analyzed by optical microscopy. The data were analyzed using the One-way analysis of variance (ANOVA) and Student's t-test with the level of significance at P=.05. RESULTS. The group $IT4_S$ had the significantly highest values and group IT2 the lowest, for both yield strength and fracture strength. Groups $IT4_N$ and ET4 had similar yield and fracture strengths despite having different connection designs. Group MT2 and group IT2 had significant differences in yield and fracture strength although they were made by the same material as titanium grade 2. The implant system of the similar fixture-abutment interfaces and the same materials showed the similar characteristics of deformation. CONCLUSION. A longer internal connection and titanium grade 4 of the implant system is advantageous for static overloading condition. However, it is not only the connection design that affects the stability. The strength of the titanium grade as material is also important since it affects the implant stability. When using the implant system made of titanium grade 2, a larger diameter fixture should be selected in order to provide enough strength to withstand overloading.

• Physical Therapy Rehabilitation Science
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• v.9 no.2
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• pp.105-112
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• 2020

Objective: To investigate the effects of training using a trunk control robot (TCR) system combined with conventional therapy (CT) on balance and gait abilities in persons with chronic stroke. Design: Two-group pretest-posttest design. Methods: Thirty-five subjects with chronic stroke were randomly assigned to either the TCR group (n=17) or the trunk extension-training (TET) group (n=18). Both groups performed CT for 30 minutes, after which the TCR group performed TCR training and the TET group performed trunk extension training for 20 minutes. Both groups performed the therapeutic interventions 3 days per week for 6 weeks. Balance ability was evaluated using the Berg Balance Scale (BBS), and the Timed Up-and-Go (TUG) test. Gait ability was measured using the 10 m Walk Test (10MWT) and the NeuroCom Smart Balance Master. Results: TCR group showed significant improvements in static balance (weight bearing) and dynamic balance (weight shifting speed, weight shifting direction, BBS, and TUG), 10MWT, gait speed, and step width (p<0.05); step length was not significant. The TET group showed a significant partial improvement of dynamic balance (weight shifting speed, weight shifting direction, BBS, and 10MWT (p<0.05), but the improvements in static balance, TUG, gait speed, and step width and step length was not significant. Additionally, significant differences in static balance, dynamic balance (weight shifting speed, weight shifting direction, BBS, and TUG), 10MWT, gait speed, and step width were detected between groups (p<0.05). Conclusions: TCR training combined with CT is effective in improving static and dynamic balance, as well as gait abilities in persons with chronic stroke.

• Journal of Korean Society of Steel Construction
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• v.18 no.2
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• pp.173-180
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• 2006

The seismic responses of a building are affected by the base soil conditions. In this study, linear time-history seismic analysis and nonlinear pushover static seismic analysis were performed to estimate the base shear forces of 3-, 5-, and 7-story steel buildings, considering the rigid and soft soil conditions. Foundation soil stiffness, based on the equivalent static stiffness formula, is used for the damper, one of the Link elements in SAP 2000. The base shear forces of the steel buildings, estimated through time-history analysis using the general-purpose structural-analysis program of SAP 2000, were compared with those calculated using the domestic seismic design code, the UBC-97 design response spectrum. and pushover static nonlinear analysis. The steel buildings designed for gravity and wind loads showed elastic responses with a moderate earthquake of 0.11 g, while the elastic soft-soil layer increased the displacement and the base shear force of the buildings due to soil-structure interaction and soil amplification. Therefore, considering the characteristics of the soft-soil layer, it is more reasonable to perform an elastic seismic analysis of a building's structure during weak or moderate earthquakes.

• Tribology and Lubricants
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• v.36 no.6
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• pp.332-341
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• 2020

High-speed turbomachinery implements gas foil bearings (GFBs) due to their distinctive advantages, such as high efficiency, lesser part count, and lower weight. This paper provides the test results of the static structural stiffnesses and loss factors of bump-type foil thrust bearings with increasing preload and bearing deflection. The focus of the current work is to experimentally quantify variability in structural stiffnesses and loss factors among the four test thrust bearings with identical design values and material of the bump and top foil geometries using the same (open-source) fabrication method. A simple test setup, using a rigidly mounted non-rotating shaft and thrust disk, measures the bearing bump deflections with increasing static loads on the test bearing. The inner and outer diameters of the test bearings are 41 mm and 81 mm, respectively. The loss factor, best-representing energy dissipation in the test bearings, is estimated from the area inside the local hysteresis loop of the load versus the bearing deflection curve. The measurements show that structural stiffnesses and loss factors of the test bearings significantly rely on applied preloads and bearing deflections. Local structural stiffnesses of the test bearings increase with applied preloads but decrease with bearing deflections. Changes of loss factors are less sensitive to applied preloads and bearing deflections compared to those of structural stiffnesses. Up to 35% variability in static load structural stiffnesses is found between bearings, while up to 30% variability in loss factors is found between bearings.

• Steel and Composite Structures
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• v.48 no.2
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• pp.113-130
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• 2023

The present manuscript aims to investigate the deviation between the middle surface (MS) and neutral surface (NS) formulations on the static response of bi-directionally functionally graded (BDFG) porous plate. The higher order shear deformation plate theory with a four variable is exploited to define the displacement field of BDFG plate. The displacement field variables based on both NS and on MS are presented in detail. These relations tend to get and derive a new set of boundary conditions (BCs). The porosity distribution is portrayed by cosine function including three different configurations, center, bottom, and top distributions. The elastic foundation including shear and normal stiffnesses by Winkler-Pasternak model is included. The equilibrium equations based on MS and NS are derived by using Hamilton's principles and expressed by variable coefficient partial differential equations. The numerical differential quadrature method (DQM) is adopted to solve the derived partial differential equations with variable coefficient. Rigidities coefficients and stress resultants for both MS and NS formulations are derived. The mathematical formulation is proved with previous published work. Additional numerical and parametric results are developed to present the influences of modified boundary conditions, NS and MS formulations, gradation parameters, elastic foundations coefficients, porosity type and porosity coefficient on the static response of BDFG porous plate. The following model can be used in design and analysis of BDFG structure used in aerospace, vehicle, dental, bio-structure, civil and nuclear structures.

• Aerospace Engineering and Technology
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• v.4 no.1
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• pp.129-142
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• 2005

A semi-monocoque truncated cone structure, which is a main structure for the payload adapter of KSLV-I, was designed. Static test was performed to confirm the reliability of the cone structure under the design loads. Strains and displacements are measured during four load cases; the compressive axial, pure bending, pure shear, and combined loading conditions. The results showed that the cone structure satisfies the design requirements. An equivalent axial load was applied to the cone structure so that the global buckling of the cone structure occurred. The measured buckling load was compared with the predicted one by finite element method. The results show a good agreement.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2009.10a
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• pp.473-477
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• 2009

In general, the softer the stiffness of a linear vibration isolator the better the performance of isolation can be achieved. However, the stiffness of the isolator cannot be made too soft because it needs a sufficient stiffness to hold the load. This is the most critical limitation of a linear vibration isolator. Recently, a HSLDS (High-Static-Low-Dynamic-Stiffness) magnetic vibration isolator was proposed to overcome this fundamental limitation. The suggested isolator utilizes two pairs of attracting magnets that that introduces negative stiffness. Previously, this new type of vibration isolator was merely introduced and showed a possibility of practical use. In this paper, detailed dynamics of the HSLDS magnetic isolator are studied using computer simulations. Then, the isolation performance is examined for various design parameters to aid the practical use.

• Journal of the Korean Society for Precision Engineering
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• v.25 no.8
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• pp.96-103
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• 2008

In this study, we performed the biomechanical analysis of cervical plate systems by using a computer simulation based on finite element method to derive reliable model by analysis of design variables and fatigue behavior. To simulate the cervical spine movement in-vivo state by surgery, we modeled the cervical plate system which consisted of screws, rings, rivets, and plate and Ultra High Molecular Weight Polyethylene (UHMWPE) Block. The experiment of cervical plate system followed the ASTM F1717 standards that covered the materials and methods for the static and fatigue testing. The result of computer simulation is compared with experimented test. We expected this study is to derive reliable results by analysis of design variables and fatigue behavior for developing a new model.