• Title/Summary/Keyword: state

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Substrate Ground State Binding Energy Concentration Is Realized as Transition State Stabilization in Physiological Enzyme Catalysis

  • Britt, Billy Mark
    • BMB Reports
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    • v.37 no.5
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    • pp.533-537
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    • 2004
  • Previously published kinetic data on the interactions of seventeen different enzymes with their physiological substrates are re-examined in order to understand the connection between ground state binding energy and transition state stabilization of the enzyme-catalyzed reactions. When the substrate ground state binding energies are normalized by the substrate molar volumes, binding of the substrate to the enzyme active site may be thought of as an energy concentration interaction; that is, binding of the substrate ground state brings in a certain concentration of energy. When kinetic data of the enzyme/substrate interactions are analyzed from this point of view, the following relationships are discovered: 1) smaller substrates possess more binding energy concentrations than do larger substrates with the effect dropping off exponentially, 2) larger enzymes (relative to substrate size) bind both the ground and transition states more tightly than smaller enzymes, and 3) high substrate ground state binding energy concentration is associated with greater reaction transition state stabilization. It is proposed that these observations are inconsistent with the conventional (Haldane) view of enzyme catalysis and are better reconciled with the shifting specificity model for enzyme catalysis.

Investigating the Association between Residual State Ownership and Privatized Firm Efficiency

  • NGUYEN, Manh Hoang;VO, Quy Thi
    • The Journal of Asian Finance, Economics and Business
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    • v.7 no.5
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    • pp.225-236
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    • 2020
  • This paper examines empirically the net impact of residual state ownership on privatized firm efficiency in the transitional context of Vietnam. Vietnamese privatization has its own characteristics. Instead of mass and full privatization, Vietnam has chosen a partial and gradual path. Thus, it is important to assess the net impact of residual state ownership on privatized firms during the post-privatization period. This study employs stochastic frontier analysis to investigate the association between residual state ownership and the efficiency of privatized firms, using a sample of all privatized firms that are listed on the Vietnamese stock exchanges over the period from 2007 to 2017. Also, two-stage least squares regression is incorporated into the model to deal with potential endogeneity issues. Our study provides evidence that state ownership should not be considered as a pure source of agency problems. Indeed, the net impact of residual state ownership on privatized firm efficiency is non-monotonic, and the relationship between residual state ownership and privatized firm efficiency is under an inverted U-shape. A moderate level (less than 50%) of residual state ownership might be beneficial to privatized firm efficiency whereas too much state ownership is detrimental to the efficiency of privatized firms.

Rovibrational Energy Transitions and Coupled Chemical Reaction Modeling of H+H2 and He+H2 in DSMC

  • Kim, Jae Gang
    • International Journal of Aeronautical and Space Sciences
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    • v.16 no.3
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    • pp.347-359
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    • 2015
  • A method of describing the rovibrational energy transitions and coupled chemical reactions in the direct simulation Monte Carlo (DSMC) calculations is constructed for $H(^2S)+H_2(X^1{\Sigma}_g)$ and $He(^1S)+H_2(X^1{\Sigma}_g)$. First, the state-specific total cross sections for each rovibrational states are proposed to describe the state-resolved elastic collisions. The state-resolved method is constructed to describe the rotational-vibrational-translational (RVT) energy transitions and coupled chemical reactions by these state-specific total cross sections and the rovibrational state-to-state transition cross sections of bound-bound and bound-free transitions. The RVT energy transitions and coupled chemical reactions are calculated by the state-resolved method in various heat bath conditions without relying on a macroscopic properties and phenomenological models of the DSMC. In nonequilibrium heat bath calculations, the state-resolved method are validated with those of the master equation calculations and the existing shock-tube experimental data. In bound-free transitions, the parameters of the existing chemical reaction models of the DSMC are proposed through the calibrations in the thermochemical nonequilibrium conditions. When the bound-free transition component of the state-resolved method is replaced by the existing chemical reaction models, the same agreement can be obtained except total collision energy model.

Digital Transformations to Improve the Work and Distribution of the State Scholarships Programs

  • Kireyeva, Anel A.;Lakhonin, Vassiliy;Kalymbekova, Zhanna
    • Journal of Distribution Science
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    • v.17 no.3
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    • pp.41-47
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    • 2019
  • Purpose - Based on the analysis of Kazakhstan's experience of digital transformation, this study suggests a concept for digital solution to optimize organizational process, create trust networking between the center of state scholarships programs and recipients. In addition, the authors contribute to the current discussions of an effective digital transformation of state services. Research design, data, and methodology - Policy analysis is based on the combination of both primary and secondary materials collected during a Policy Research Project conducted in Kazakhstan in 2017. It involved semi-structured interviews with the state scholarship' recipients, ICT experts and findings from academic articles. Results - Findings are represented via Policy Development Matrix - a table with three options (status quo, partial change, total change) to deal with policy challenges. Authors suggest a concept for digital solution following the Customer Relationship Management (CRM) principles for optimizing core business processes, communication and networking strategies of the state scholarships program. Conclusions - At the time when digitalization becomes trending for states, the transformation of the state education policy is inevitable. The rapid development of digital technologies creates new opportunities for a single integration platform with key principles of Smart Remote Management in the state scholarships programs.

The Review of the State Policy in the IT Industry and HRD in South Korea

  • Park, In-Sub
    • Journal of Digital Convergence
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    • v.7 no.1
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    • pp.19-29
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    • 2009
  • This article is concerned to investigate the changing nature of the role of the state in relation to industrial policy to foster the IT industry in the Republic of Korea. In doing this, it has started with economic globalization introduced to the Korean political economy since the late 1980s. It has identified in what ways the state responded to the change, and to what extent the role of the state has fundamentally been changed in the context of policy mechanism in the process towards facilitating the IT industry in Korea. In addition, it presented how the state played a role in skill formation in relation to the industrial policy. In consequence, the role of the Korean state in fostering the IT industry has fundamentally changed from that as the developmental state in the industrialization process. In the process, that the strategic co-ordination role of the state and relations between the state and private capitals and societies are very significant to achieve the economic goal is presented as results, as well as some future tensions that would encounter in the way of charting the current policies.

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A Discrete State-Space Control Scheme for Dynamic Voltage Restorers

  • Lei, He;Lin, Xin-Chun;Xue, Ming-Yu;Kang, Yong
    • Journal of Power Electronics
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    • v.13 no.3
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    • pp.400-408
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    • 2013
  • This paper presents a discrete state-space controller using state feedback control and feed-forward decoupling to provide a desirable control bandwidth and control stability for dynamic voltage restorers (DVR). The paper initially discusses three typical applications of a DVR. The load-side capacitor DVR topology is preferred because of its better filtering capability. The proposed DVR controller offers almost full controllability because of the multi-feedback of state variables, including one-beat delay feedback. Feed-forward decoupling is usually employed to prevent disturbances of the load current and source voltage. Directly obtaining the feed-forward paths of the load current and source voltage in the discrete domain is a complicated process. Fortunately, the full feed-forward decoupling strategy can be easily applied to the discrete state-space controller by means of continuous transformation. Simulation and experimental results from a digital signal processor-based system are included to support theoretical analysis.

Formation Behavior of Passive State Film on Stainless Steel for Metallic Ion Concentration in Electropolishing Solution (전해 연마액 금속 이온 농도에 따른 스테인리스 스틸의 부동태 피막 형성 거동)

  • Oh, Jong Su;Kang, Eun-Young;Jeong, Dae-Yong
    • Korean Journal of Materials Research
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    • v.32 no.4
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    • pp.230-236
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    • 2022
  • The formation behavior of a passive state film on the surface of STS304 in electrolytic solution was analyzed to determine its metallic ion composition. The properties of passive state films vary depending on the Fe and Cr ions in the electrolytic solution. It was observed that the passive state film surface became flat and glossy as the concentration of Fe and Cr ions in the electrolytic solution increased. The corrosion resistance property of the passive state film was proportional to the amount of Fe and Cr in the electrolytic solution. An initial passive state film with high Fe concentration was formed on the surface of STS304 during early electrolytic polishing. Osmotic pressure of Fe ions occurs between the passive state film and electrolytic solution due to the Fe ion concentration gradient. The Fe in the passive state film is dissolved into the electrolyte, and Cr fills up the Fe ion vacancies. As a result, a good corrosion-resistant floating film was formed. The more Fe ions in the electrolytic solution, the faster the film is formed, and as a result, a flat passive state film containing a large amount of Cr can be formed.

A Hardware-Based String Matching Using State Transition Compression for Deep Packet Inspection

  • Kim, HyunJin;Lee, Seung-Woo
    • ETRI Journal
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    • v.35 no.1
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    • pp.154-157
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    • 2013
  • This letter proposes a memory-based parallel string matching engine using the compressed state transitions. In the finite-state machines of each string matcher, the pointers for representing the existence of state transitions are compressed. In addition, the bit fields for storing state transitions can be shared. Therefore, the total memory requirement can be minimized by reducing the memory size for storing state transitions.

A Proposal of State Reduction Algorithm and the Development of a Graphic Editor for State Machine Synthesizer (상태합성기 설계를 위한 상태축소 알고리듬 제안 및 그래픽 에디터 개발에 관한 연구)

  • 이근만;임인칠
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.17 no.4
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    • pp.415-423
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    • 1992
  • In this paper, we developed a Graphic Editor which automatically translated the state transition graph into state CHDL. Also, an algorithm for efficient state minimization is presented to reduce the redundancy state transition table.

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