• Title/Summary/Keyword: state

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Assessing Markov and Time Homogeneity Assumptions in Multi-state Models: Application in Patients with Gastric Cancer Undergoing Surgery in the Iran Cancer Institute

  • Zare, Ali;Mahmoodi, Mahmood;Mohammad, Kazem;Zeraati, Hojjat;Hosseini, Mostafa;Naieni, Kourosh Holakouie
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.1
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    • pp.441-447
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    • 2014
  • Background: Multi-state models are appropriate for cancer studies such as gastrectomy which have high mortality statistics. These models can be used to better describe the natural disease process. But reaching that goal requires making assumptions like Markov and homogeneity with time. The present study aims to investigate these hypotheses. Materials and Methods: Data from 330 patients with gastric cancer undergoing surgery at Iran Cancer Institute from 1995 to 1999 were analyzed. To assess Markov assumption and time homogeneity in modeling transition rates among states of multi-state model, Cox-Snell residuals, Akaikie information criteria and Schoenfeld residuals were used, respectively. Results: The assessment of Markov assumption based on Cox-Snell residuals and Akaikie information criterion showed that Markov assumption was not held just for transition rate of relapse (state 1 ${\rightarrow}$ state 2) and for other transition rates - death hazard without relapse (state 1 ${\rightarrow}$ state 3) and death hazard with relapse (state 2 ${\rightarrow}$ state 3) - this assumption could also be made. Moreover, the assessment of time homogeneity assumption based on Schoenfeld residuals revealed that this assumption - regarding the general test and each of the variables in the model- was held just for relapse (state 1 ${\rightarrow}$ state 2) and death hazard with a relapse (state 2 ${\rightarrow}$ state 3). Conclusions: Most researchers take account of assumptions such as Markov and time homogeneity in modeling transition rates. These assumptions can make the multi-state model simpler but if these assumptions are not made, they will lead to incorrect inferences and improper fitting.

항만국통제의 법적 근거와 국내시행상의 문제

  • Lee, Yun-Cheol
    • Proceedings of KOSOMES biannual meeting
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    • 2005.05a
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    • pp.195-208
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    • 2005
  • The flag State is primarily responsible for implementing international maritime conventions(IMO conventions) and national laws and other standards as far as its own vessels are concerned, on the other hand the port State exercise its rights for the safety and marine environment under international law especially UNCLOS within port and territorial sea. In particular, the port State may take appropriate measures including detention of ships identified as sub-standard vessels which are considered as port State's supplementary role aiming for implementing international and national and regulations. But in the course of implementing port state control, international disputes may happen between port state, coastal state and flag state in spite of making all possible efforts to avoid these disputes. This paper aims to consider legal grounds on port state control(PSC) in international conventions and national laws concerned and deals with contradictions between international and national law arising from exercising PSC by port state control officers(PSCOs).

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Mixed Wave Function for Heavy Fermion Compounds

  • Bang, Yun-Kyu
    • Progress in Superconductivity
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    • v.11 no.2
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    • pp.135-140
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    • 2010
  • We propose a variational wave function for the ground state of the magnetic heavy fermion (HF) systems, in which both the Kondo and the RKKY interactions are variationally incorporated and the local f-orbital state exists as a linear combination of a full local moment state and a fully compensated state (mixed wave state). We describe the mechanism for the mixed wave ground state based on the large-N treatment of the Kondo lattice Hamiltonian added with RKKY interaction. With the mixed wave ground state we can explain several puzzling experiments in magnetic HF compounds such as a small value of local moment, coexistence of the antiferromagnetic (AFM) and the paramagnetic (PM) phases, local quantum criticality, etc.

The Developments of State CHDL and Two-Level Minimizer for State Machine Synthesizer (상태합성기(State Machine Synthesizer) 설계를 위한 상태 CHDL 개발 및 Two-level minimizer 개발에 관한 연구)

  • 김희석;이근만;임인칠
    • Journal of the Korean Institute of Telematics and Electronics A
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    • v.29A no.4
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    • pp.83-90
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    • 1992
  • The state machine synthesizer is widely used to FSM synthesis. In this paper, we developed the state machine description language "state CHDL" such as IF, THEN, ELSE, SWITCH, CASE statements. Also, an algorithm for efficient state minimization and two level minimizer of FSM and graphical user interface-pin map window, supporting the designer with input-ouput effency, are presented.

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Optimal Sliding-Mode Controller Design based on State Observer (관측기 기반 하의 최적 슬라이딩 모드 제어기 설계)

  • Hong, Min-Suk;You, Kwan-Ho
    • Proceedings of the KIEE Conference
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    • 2005.05a
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    • pp.119-121
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    • 2005
  • The sliding-mode control technique could make a system unstable which external disturbance and uncertainty exists in. This paper suggests a robust sliding-mode control algorithm which can be applied to a linear system with parameter uncertainties. To reduce the chattering effect, the whole system is comprised of using a state variable in which the state's estimated value is added. The condition of estimated state results from state observer. The proposed control algorithm uses the optimal feedback controller following the dynamic system equation which consists of a state variable resulting from its own state variable, controller input, estimated state variable. Through comparison with the time optimal control algorithm using simulation, the suggested algorithm shows the improved stability and robustness while it manifests the fast tracking characteristics.

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A study on the speaker adaptation in CDHMM usling variable number of mixtures in each state (CDHMM의 상태당 가지 수를 가변시키는 화자적응에 관한 연구)

  • 김광태;서정일;홍재근
    • Journal of the Korean Institute of Telematics and Electronics S
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    • v.35S no.3
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    • pp.166-175
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    • 1998
  • When we make a speaker adapted model using MAPE (maximum a posteriori estimation), the adapted model has one mixture in each state. This is because we cannot estimate a number of a priori distribution from a speaker-independent model in each state. If the model is represented by one mixture in each state, it is not well adadpted to specific speaker because it is difficult to represent various speech informationof the speaker with one mixture. In this paper, we suggest the method using several mixtures to well represent various speech information of the speaker in each state. But, because speaker-specific training dat is not sufficient, this method can't be used in every state. So, we make the number of mixtures in each state variable in proportion to the number of frames and to the determinant ofthe variance matrix in the state. Using the proposed method, we reduced the error rate than methods using one branch in each state.

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On QoS Routing and Path Establishment in the Presence of Imprecise State Information

  • Yuan, Xin;Duan, Zhenhai
    • Journal of Communications and Networks
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    • v.9 no.4
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    • pp.356-367
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    • 2007
  • In large networks, maintaining precise global network state information is impossible. The imprecise network state information has significant impacts on Quality-of-Service(QoS) routing and path establishment. In this paper, we develop analytical models for investigating the QoS routing schemes that are designed to tolerate imprecise network state information, and study the performance of various QoS routing schemes, including randomized routing, multi-path routing, and probability based routing, using both the models and simulations. We further propose a new mechanism, called local rerouting, that improves the effectiveness of QoS path establishment in the presence of imprecise global network state information. Local rerouting is orthogonal to existing schemes for dealing with imprecise state information and can be used in conjunction with them to alleviate the impacts of the imprecise information. The results of our performance study indicate that local rerouting is robust and effective.

Extended State Estimation Algorithm in Power Systems (확장된 전력 상태추정 알고리즘 개발)

  • Shon, H.S.;Ha, Y.K.;Ryu, H.S.;Moon, Y.H.;Song, K.B.;Park, J.D.
    • Proceedings of the KIEE Conference
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    • 2001.07a
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    • pp.178-180
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    • 2001
  • State estimation in power system is to estimate state variable value which minimizes the error from the real state measured by the gauge and connection state of the circuit breaker. In the past, it was difficult to determine measure function considering the correlation of the measured values. In this paper, an extended state estimation is proposed to process easily various kinds of estimation variable. The proposed algorithm is developed by expanding state variable concept based on many measured values and treating correlation between estimation variable and state variable, it is considered that the state variable satisfy some limitations named "Equality Limitation conditions".

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