• Title/Summary/Keyword: standard of diagnosis

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Granular cell tumor of the esophagus in an adolescent

  • Lee, Ji Sun;Ko, Kyung Ok;Lim, Jae Woo;Cheon, Eun Jeong;Kim, Young Jin;Son, Jang Sin;Yoon, Jung Min
    • Clinical and Experimental Pediatrics
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    • v.59 no.sup1
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    • pp.88-91
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    • 2016
  • Esophageal granular cell tumor (GCT) is a rare neoplasm originating from the Schwann cells of the submucosal neuronal plexus. Histology is the gold standard for its diagnosis. Endoscopic resection or surgical excision should be considered, depending on the potential for malignancy. Here, we report a case of an esophageal GCT in an adolescent. A 12-year-old boy presented with a 1-year history of dysphagia and vomiting. Upper gastrointestinal endoscopic examination and esophagography showed narrowing of the midesophagus, and computed tomography angiography of the thoracic aorta revealed an esophageal or periesophageal mass posterior to the paratracheal segment of the esophagus. The tumor was surgically excised, and based on the pathological findings, esophageal GCT was diagnosed.

Association between Temporomandibular Disorders and Occupations by Korean Standard Classification of Occupations

  • Kim, Ji-Su;Kim, Young-Ae;Heo, Jun-Young;Ok, Soo-Min;Kim, Kyung-Hee;Ahn, Yong-Woo;Jeong, Sung-Hee
    • Journal of Oral Medicine and Pain
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    • v.40 no.1
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    • pp.17-27
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    • 2015
  • Purpose: The purpose of this study was to investigate occupational distribution of temporomandibular disorders (TMD) patients and their diagnosis according to occupations and to evaluate the relationship between TMD and occupations. Work-related factors which might aggravate TMD symptoms were also evaluated. Methods: We investigated 316 TMD patients, aged from 13 to 65 years old, who had visited the Department of Oral Medicine in Pusan National University Dental Hospital. The subjects who have a job were assessed using TMD analysis examination and occupation questionnaire. The level of significance was p-value<0.05. Result: This study presented that the diagnoses according to occupations were not significant, but work-related factors such as verbal work and poor posture were related with TMD symptoms. Conclusions: Proper education is essential to prevent aggravation of TMD symptoms because TMD symptoms were more related to work environment than a specific occupation.

Quantitative Analysis of Lung Contusion (폐좌상의 정량분석)

  • 오중환
    • Journal of Chest Surgery
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    • v.27 no.10
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    • pp.833-837
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    • 1994
  • Lung contusion due to blunt chest trauma is the most common lung injury and correlated with the clinical course and prognosis. Its diagnosis by CT[Computerized Tomogram] gives a more clear and understandable three dimensional view, by which we are able to measure the volume of the contused and entire lung. Other variables are arterial blood gas, number of rib fracture, presence of hemopneumothorax, sternal fracture and clavicle fracture, number of associated non-thoracic injuries, ventilator time and presence of pulmonary complication. Percentage[%] of lung contusion are expressed as mean $\pm$ standard deviation and data analysis was performed by means of multivariate repeated measures analysis of variance to detect significant differences in variables between positive thoracic injury group and negative group. The paired t-test was used. Differences of percentage of lung contusion between groups were assessed by one-way analysis of variance. Simple linear regression was used to perform correlation analysis in the number of rib fracture and ventilator time. A p value less than 0.05 was considered statistically significant. Pneumothorax and the number of associated other injuries affect the amount of lung contusion and pulmonary complication group has more contused lung volume. Arterial blood gas study shows no correlation with the amount of lung contusion statistically. The number of rib fracture correlated with the amount of lung contusion, which also correlated with ventilator time[r=0.56, p<0.05]. In conclusion, quantitative anlysis of lung contusion by CT predicts the clinical course and treatment such as ventilator care.

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Two Decades of Experience with Ductal Carcinoma in Situ of the Breast in the Cancer Institute of Tehran, Iran

  • Omranipour, Ramesh;Alipour, Sadaf;Hadji, Maryam;Bagheri, Khojasteh
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.6
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    • pp.2771-2776
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    • 2014
  • Background: Breast cancer screening and higher quality mammography have resulted in an increase in the diagnosis of ductal carcinoma in situ worldwide. We compared the incidence and other factors in our cases of ductal carcinoma in situ between two recent decades. Materials and Methods: Medical records of cases of ductal carcinoma in situ who had been admitted to the surgery wards of the Cancer Institute of Tehran, Iran were evaluated from March 1993 to March 2003 as phase 1, and from April 2003 to April 2013 as phase 2. Results: Ratio of ductal carcinoma in situ to overall breast cancer was 1.27 and 3.93 in phases 1 and 2, respectively. Rates of excisional or incisional biopsies versus core needle biopsies and clinically versus mammographically detected cases as well as median size of tumors dropped between the 2 phases while a substantial rise in the number of patients attending for screening was seen in this time period. Surgical treatments followed a trend from modified radical mastectomy and axillary lymphatic dissection toward breast conserving surgery and sentinel node dissection or no axillary intervention. Conclusions: Our study shows a considerable trend toward earlier detection of breast cancer and evolution of treatment strategies toward standard less invasive surgery of DCIS in Iran.

Development of Nested Polymerase Chain Reaction for the Detection of Mycoplasma hyopneumoniae in Formalin-fixed Paraffin-embedded Lung Tissues

  • Lim, Jung-eun;Ha, Seung-kwon;Chae, Chan-hee
    • Proceedings of the Korean Society of Veterinary Pathology Conference
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    • 2003.10a
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    • pp.29-29
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    • 2003
  • Mycoplasma hyopneumoniae is among the most prevalent and important infectious agents associated with porcine respiratory disease complex. The airway dagame caused by M. hyopneumoniae adversely affect the pulmonary host defense mechanisms and may lead to secondary bacterial infections. Culture is considered to be the "gold standard" for diagnosis but this is a very slow and labor-intensive procedure. Isolation of M. hyopneumoniae is complicated by its fastidious nature and extremely slow growth. Thirty days of incubation may be necessary to detect the organism in primary broth cultures. The purposes of the study were (ⅰ) to develop nested PCR for the detection of M. hyopneumoniae for the detection of M. hyopneumoniae DNA in the formalin-fixed, paraffin-embedded lung tissues from experimentally and naturally infected pigs and (ⅱ) to compare the utility of nested PCR with in situ hybridization. (omitted)

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Parameter Extraction for the Distinction between Denervation Potentials and Endplate Spikes on EMG Diagnosis (근전도검사에서 나타나는 탈신경전위와 종판전위와의 구별을 위한 변수추출)

  • Hwang, Y.S.;Choi, H.B.;Im, J.J.;Park, I.S.
    • Proceedings of the KOSOMBE Conference
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    • v.1996 no.11
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    • pp.203-206
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    • 1996
  • During the electromyographic evaluation, the presence and site of lession may be predicted by a detection of denervation potentials such as fibrllation potentials or positive sharp waves in the group of muscles. Currently, clinicians diagnose the neuropathy by detecting fibrillation potentials during EMG tests, and sometimes it is not easy to distinguish between denervation potentials and endplate spikes. The purpose of this study was to find statistically significant parameters for the quantitative distinction between denervation potentials and endplate spikes. Endplate spikes and denervation potentials from the EDB muscle of 10 patients were extracted. Also, EMG signals were classified by experienced clinicians, and were collected using a 12 bit ADC with a sampling rate of 20KHz for the duration of 400msec. In order to find statistically significant parameters, positive and negative peaks were used for analysis. As a results, standard deviation of the endplate spikes and denervation potentials showed more significant difference than others specially for the positive sharp waves. It was concluded that the results of this study could be used to develope an automated system of a EMG analysis.

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False-Negative Results of Real-Time Reverse-Transcriptase Polymerase Chain Reaction for Severe Acute Respiratory Syndrome Coronavirus 2: Role of Deep-Learning-Based CT Diagnosis and Insights from Two Cases

  • Dasheng Li;Dawei Wang;Jianping Dong;Nana Wang;He Huang;Haiwang Xu;Chen Xia
    • Korean Journal of Radiology
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    • v.21 no.4
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    • pp.505-508
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    • 2020
  • The epidemic of 2019 novel coronavirus, later named as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is still gradually spreading worldwide. The nucleic acid test or genetic sequencing serves as the gold standard method for confirmation of infection, yet several recent studies have reported false-negative results of real-time reverse-transcriptase polymerase chain reaction (rRT-PCR). Here, we report two representative false-negative cases and discuss the supplementary role of clinical data with rRT-PCR, including laboratory examination results and computed tomography features. Coinfection with SARS-COV-2 and other viruses has been discussed as well.

Comparative Study of Diagnostic Accuracy Rate by Sasang Constitutions on Measurement Method of Body Shape (체형측정 방법에 따른 사상체질 진단정확률 비교 연구)

  • Kim, Jong-Won;Sul, Yu-Kyung;Choi, Jae-Jung;Kwon, Suk-Dong;Kim, Kyu-Kon;Lee, Yong-Tae
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.21 no.1
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    • pp.338-346
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    • 2007
  • For Objectivity development of the body shape that is an importance standard for the classification of sasang constitutional medicine diagnosis, We made a comparison between Automatic & Physical measuring. This study uses 2 attitude which lies down & standing. We measured the body of patients(Width 5 places and circumference 8 places) and analyzed the anthropometric data dividing into sex, age, BMI. 296 patients's data are used in the analysis.

Clinical Practice Guideline for Soeumin Disease of Sasang Constitutional Medicine: Greater Yin Symptomatology (소음인체질병증 임상진료지침: 태음병)

  • Hwang, Min-Woo;Park, Hye-Seon;Lee, Eui-Ju
    • Journal of Sasang Constitutional Medicine
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    • v.26 no.1
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    • pp.45-54
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    • 2014
  • Objectives This research was proposed to present Clinical Practice Guideline(CPG) for Soeumin Disease of Sasang Constitutional Medicine(SCM): Greater Yin Symptomatology. This CPG was developed by the national-wide experts committee consisting of SCM professors. Methods First, it was performed that search and collection of literature related SCM such as "Dongeuisusebowon", Textbook of SCM, Clinical Guidebook of SCM and Fundamental research to standardize diagnosis of Sasang Constitutional Medicine. And journal search related clinical trial or Human complementary medicine of SCM was performed domestic and overseas. Finally, 1 article was selected and included in CPG for Greater Yin Symptomatology of Stomach Cold-based Interior Cold disease in Soeumin disease. Results & Conclusions CPG of Greater Yin symptomatology in Soeumin Disease include classification, definition and standard symptoms of each pattern. Greater Yin symptomatology is classified into mild and moderate pattern by severity. Greater Yin Symptomatology Mild pattern is classified into Greater Yin Symptomatology accompanied abdominal pain and bowel irritability and Greater Yin pattern accompanied Epigastric stuffiness and fullness. And Greater Yin Symptomatology moderate pattern is classified into Greater Yin pattern accompanied Jaundice, Greater Yin pattern accompanied Edema and Greater Yin pattern by Yin toxin.

Two Cystic Cavernous Angiomas after Radiotherapy for Atypical Meningioma in Adult Woman : Case Report and Literature Review

  • Ruggeri, Andrea Gennaro;Donnarumma, Pasquale;Pichierri, Angelo;Delfini, Roberto
    • Journal of Korean Neurosurgical Society
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    • v.55 no.1
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    • pp.40-42
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    • 2014
  • A correlation between radiation therapy and cavernoma has been suspected since 1994. Since then, only a few cases of radio-induced cavernomas have been reported in the literature (85 patients). Most of them were children, and the most frequent original tumour had been medulloblastoma. The authors report a case of two cystic cavernous angiomas after radiation therapy for atypical meningioma in adult woman. This is the first case of cavernous angioma after radiotherapy for low grade meningioma. A 39-year-old, Latin american woman was operated on for a frontal atypical meningioma with intradiploic component and adjuvant radiotherapy was delivered (6000 cGy local brain irradiation, fractionated over 6 weeks). Follow-up MR imaging showed no recurrences of the tumour and no other lesions. Ten years later, at the age of 49, she consulted for progressive drug-resistant headache. MR imaging revealed two new well defined areas of different signal intensity at the surface of each frontal pole. Both lesions were surgically removed; the histopathological diagnosis was cavernous angioma. This is the first case of cavernous angioma after radiation therapy for atypical meningioma : it confirms the development of these lesions after standard radiation therapy also in patients previously affected by non-malignant tumours.