• Title/Summary/Keyword: standard GA

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Damage Effects Modeling by Chlorine Leaks of Chemical Plants (화학공장의 염소 누출에 의한 피해 영향 모델링)

  • Jeong, Gyeong-Sam;Baik, Eun-Sun
    • Fire Science and Engineering
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    • v.32 no.3
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    • pp.76-87
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    • 2018
  • This study describes the damage effects modeling for a quantitative prediction about the hazardous distances from pressurized chlorine saturated liquid tank, which has two-phase leakage. The heavy gas, chlorine is an accidental substance that is used as a raw material and intermediate in chemical plants. Based on the evaluation method for damage prediction and accident effects assessment models, the operating conditions were set as the standard conditions to reveal the optimal variables on an accident due to the leakage of a liquid chlorine storage vessel. A model of the atmospheric diffusion model, ALOHA (V5.4.4) developed by USEPA and NOAA, which is used for a risk assessment of Off-site Risk Assessment (ORA), was used. The Yeosu National Industrial Complex is designated as a model site, which manufactures and handles large quantities of chemical substances. Weather-related variables and process variables for each scenario need to be modelled to derive the characteristics of leakage accidents. The estimated levels of concern (LOC) were calculated based on the Gaussian diffusion model. As a result of ALOHA modeling, the hazardous distance due to chlorine diffusion increased with increasing air temperature and the wind speed decreased and the atmospheric stability was stabilized.

Oral Administration of Nonionic Water-Soluble Contrast Media to Treat Meconium Obstruction in Premature Infants: A Preliminary Study

  • Hong, Hyun Sook;Kim, Sung Shin;Park, Ga Young
    • Neonatal Medicine
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    • v.28 no.1
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    • pp.22-28
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    • 2021
  • Purpose: Meconium obstruction of prematurity (MOP) predisposes premature infants to intestinal perforation and prolonged hospitalization if not diagnosed and treated promptly. A standard contrast enema is less effective to treat infants with distal ileal obstructions because the contrast may not reach the obstructed areas. In an effort to avoid risky surgery, we administered oral contrast media to seven clinically diagnosed patients with MOP whose obstructions were not relieved via conventional sonography-guided contrast enema. We retrospectively evaluated whether oral nonionic water-soluble contrast media relieves MOP. Methods: Seven of 67 premature infants with MOP were administered oral contrast media from June 2015 to January 2019. Patients were followed-up radiographically for bowel distention and evacuation of contrast media after oral administration. We recorded radiographic improvements, meconium evacuation, time to first feeding after oral contrast media administration, maternal history, and neonatal clinical factors. Results: We evaluated five male and two female infants. The median gestational ages and body weights at birth were 27+5 weeks and 890 g, respectively. Radiography in five infants revealed multiple distended intestinal loops without air-fluid interfaces. Two infants had gasless abdomens, in which only stomach gas was visible. Oral contrast media (median, 2.5 mL) were administered at a median age of 7 days; five infants (5/7, 71.4%) responded to this treatment. The remaining two infants, who had ileal stenosis and hypoganglionosis, were surgically managed. Five infants (5/7, 71.4%) had maternal risk factors, and two (28.6%) were small for gestational age. Conclusion: Nonionic oral water-soluble contrast medium can serve as a valuable adjunct treatment in premature infants with meconium obstruction.

Initial Sizing of a Roadable PAV Considering Airfoil and Engine Types (익형과 엔진 종류를 고려한 도로주행형 PAV 초기 사이징)

  • Cha, Jae-Young;Hwang, Ho-Yon
    • Journal of Advanced Navigation Technology
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    • v.23 no.1
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    • pp.44-54
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    • 2019
  • In many countries, there are needs of new transportations to replace ground congestions due to growing number of cars. In addition, the increase in the number of cars held by economic growth will further increase traffic congestion in the future. To overcome this problem, many researches have been performed for personal air vehicle (PAV). In this study, the wing loading and the power-to-weight ratio that are major design parameters for the sizing of roadable PAVs were calculated for different kinds of airfoil and engine types. I.e., in the sizing process, the study was conducted to determine the design point using the graphs of wing loading, power-to-weight ratio, brake horse power, and fuel efficiency for the given mission profiles considering domestic environments and the FAR PART 23 which is the GA class aircraft certification standard. As a result of sizing, using diesel engine require high maximum take-off weight, wing area, and power compared to gasoline engine due to more engine weight.

Constraint Analysis for the Sizing of Roadable PAV Considering Domestic Environments (국내환경을 고려한 도로주행형 PAV 사이징을 위한 구속조건 해석)

  • Cha, Jae-Young;Hwang, Ho-Yon;Lim, Eun-Ha;Kim, Seok-Beom
    • Journal of Advanced Navigation Technology
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    • v.22 no.2
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    • pp.111-122
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    • 2018
  • At present, the ground transportation system is saturated in many countries including Korea. To overcome this problem, many researches of developing a roadable personal air vehicle (PAV) are being carried out to alleviate traffic congestion and to accomplish door-to-door mobility through three-dimensional traffic system. In this study, the thrust-to-weight ratio, the wing loading, and the power-to-weight ratio that are major design parameters for the sizing of roadable PAVs were calculated under the constraints of ground roll, climb rate, maximum cruise speed, service ceiling, stall speed. Also, in the sizing process, the study was conducted to determine the design point using the graphs of thrust-to-weight ratio, wing loading, power-to-weight ratio, and brake horse power for the mission profiles considering domestic environments and the FAR PART 23 which is the GA class aircraft certification standard.

Tissue-cultured regeneration and ecological values in major bamboo species

  • Sharma, Avinash;Manpoong, Chowlani;Gohain, Anwesha;Pandey, Himanshu;Padu, Gompi;Aku, Hage
    • Journal of Ecology and Environment
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    • v.46 no.3
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    • pp.218-242
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    • 2022
  • Background: Promising specific growth regulators are employed in the tissue cultures of various bamboo species. Specific natural hardening mixtures support the acclimatization and adaptation of bamboo under protected cultivation. Results: The growth regulators like 2, 4-Dichlorophenoxyacetic acid (2, 4-D), Naphthaleneacetic Acid (NAA), Thidiazuron (TDZ), 6-Benzylaminopurine (BAP), Kinetin, Gelrite, Benzyl Adenine (BA), Indole Butyric Acid (IBA), Coumarin, Putrescine, Gibberellic acid (GA3), Indole Acetic Acid (IAA) has been widely used for callus induction, root regeneration and imposing plant regeneration in various species of bamboo such as Bambusa spp. and Dendrocalamus spp. Different combinations of growth regulators and phytohormones have been used for regenerating some of the major bamboo species. Natural hardening materials such as cocopeat, vermicompost, perlite, cow dung, farmyard manure, compost, soil, garden soil, and humus soil have been recommended for the acclimatization and adaptation of bamboo species. Standard combinations of growth regulators and hardening mixtures have imposed tissue culture, acclimatization, and adaptation in major bamboo species. Conclusions: Bamboo contributes to soil fertility improvement and stabilization of the environment. Bamboo species are also involved in managing the biogeochemical cycle and have immense potential for carbon sequestration and human use. This paper aims to review the various growth regulators, natural mixtures, and defined media involved in regenerating major bamboo species through in vitro propagation. In addition, the ecological benefits of safeguarding the environment are also briefly discussed.

A Case Report of a Patient with Post-Traumatic Stress Disorder Using Emotion to Emotion Therapy Based on Standard Manual (표준매뉴얼 기반 오지상승위치료법을 시행한 외상후스트레스장애 환자 1례)

  • Ju Yeon Cho;Jong Min Kim;Ga Hyun Lee;Seung Woo Song;Hyun Woo Lee;Jung Hyun Choi;Hyung Won Kang
    • Journal of Oriental Neuropsychiatry
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    • v.34 no.3
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    • pp.307-317
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    • 2023
  • Objectives: To introduce the progress of treatment and improve clinical use after application of Emotion-to-Emotion Therapy (ETE Therapy) for treating Post-traumatic Stress Disorder (PTSD). Methods: A patient who was diagnosed with PTSD that occurred after violence in the family mainly complained about abdominal pain, depression, and fear. We treated the patient with ETE therapy as the main treatment. Subjective Units of Distress scale (SUDs), The Core Seven-Emotions Inventory Short Form (CSEI-s), and Mentalizing the Rooms of Mind (MRM) were evaluated before and after the treatment for assessing the clinical effect. Results: After treatment, overall clinical symptoms of the patient were alleviated. This result was supported by a decrease in SUDs. There were meaningful drops in 'Fear', 'Fright', 'Sorrow' in CSEI-s scores, consistent with the direction of 'Sa-seung-Gong (思勝恐)' used as major technique of ETE therapy. Resources and positive emotions in MRM were increased after treatment. Conclusions: ETE therapy may be effective for treating PTSD. It might play a significant role in cognitive reconstruction.

Current Status of International Standardization for Durability Test Methods in Smart Clothing and Future Challenges in Enhancing Product Reliability and Quality Control (스마트 의류의 사용환경 내구성 시험에 대한 국제 표준화 현황과 제품의 신뢰성 향상 및 품질 관리를 위한 향후 과제)

  • Siyeon Kim;Ga-Young Lim;Sukyung Kim;Junghyun Lee
    • Fashion & Textile Research Journal
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    • v.25 no.3
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    • pp.398-408
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    • 2023
  • Smart clothing products can experience a decrease in performance and reliability due to various mechanical, biological, and chemical stress factors that occur throughout their life cycle. These issues can hinder consumer acceptance of the products. This study aims to enhance the reliability of smart clothing and facilitate quality control by analyzing and identifying the current status of international standardization for smart clothing and electronic textiles (e-textiles). The focus of this analysis was on the durability test methods in the use environment. Furthermore, similar standards published by different standardization organizations for durability tests were compared in depth. The study showed that a total of 27 international standards have been developed or are currently under development. The current standardization efforts mainly aim to develop functionality and durability test methods for smart clothing and e-textile products. A detailed comparison was made between two international standards (IEC 63023-204-1:2023 and AATCC TM210:2019) specifically in relation to the washing durability test method and the electrical resistance measurement standards (BS EN 16812:2016 vs AATCC EP13-2021), before and after the environmental exposure tests. Based on this comparison, several suggestions have been made and discussed for the future revision of these international standards.

Association of coffee consumption with type 2 diabetes and glycemic traits: a Mendelian randomization study

  • Hyun Jeong Cho;Akinkunmi Paul Okekunle ;Ga-Eun Yie ;Jiyoung Youn ;Moonil Kang;Taiyue Jin;Joohon Sung;Jung Eun Lee
    • Nutrition Research and Practice
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    • v.17 no.4
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    • pp.789-802
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    • 2023
  • BACKGROUND/OBJECTIVES: Habitual coffee consumption was inversely associated with type 2 diabetes (T2D) and hyperglycemia in observational studies, but the causality of the association remains uncertain. This study tested a causal association of genetically predicted coffee consumption with T2D using the Mendelian randomization (MR) method. SUBJECTS/METHODS: We used five single-nucleotide polymorphisms (SNPs) as instrumental variables (IVs) associated with habitual coffee consumption in a previous genome-wide association study among Koreans. We analyzed the associations between IVs and T2D, fasting blood glucose (FBG), 2h-postprandial glucose (2h-PG), and glycated haemoglobin (HbA1C) levels. The MR results were further evaluated by standard sensitivity tests for possible pleiotropism. RESULTS: MR analysis revealed that increased genetically predicted coffee consumption was associated with a reduced prevalence of T2D; ORs per one-unit increment of log-transformed cup per day of coffee consumption ranged from 0.75 (0.62-0.90) for the weighted mode-based method to 0.79 (0.62-0.99) for Wald ratio estimator. We also used the inverse-variance-weighted method, weighted median-based method, MR-Egger method, and MR-PRESSO method. Similarly, genetically predicted coffee consumption was inversely associated with FBG and 2h-PG levels but not with HbA1c. Sensitivity measures gave similar results without evidence of pleiotropy. CONCLUSIONS: A genetic predisposition to habitual coffee consumption was inversely associated with T2D prevalence and lower levels of FBG and 2h-PG profiles. Our study warrants further exploration.

Use of Quantitative Vertebral Bone Marrow Fat Fraction to Assess Disease Activity and Chronicity in Patients with Ankylosing Spondylitis

  • Ga Young Ahn;Bon San Koo;Kyung Bin Joo;Tae-Hwan Kim;Seunghun Lee
    • Korean Journal of Radiology
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    • v.22 no.10
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    • pp.1671-1679
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    • 2021
  • Objective: We quantitatively measured the fat fraction (FF) in the vertebrae of patients with ankylosing spondylitis (AS) using magnetic resonance imaging (MRI) and investigated the role of FF as an indicator of both active inflammation and chronicity. Materials and Methods: A total of 52 patients with AS who underwent spinal MRI were retrospectively evaluated. The FF values of the anterosuperior and anteroinferior corners of the bone marrow in the L1-S1 spine were assessed using the modified Dixon technique. AS activity was measured using the Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), Bath Ankylosing Spondylitis Functional Index (BASFI), AS Disease Activity Score (ASDAS), and serum inflammatory marker levels. AS disease chronicity was assessed by AS disease duration and the modified Stoke Ankylosing Spondylitis Spinal Score (mSASSS). Univariable and multivariable regression analyses were conducted to investigate the correlation between FF and other clinical characteristics. Results: The mean FF ± standard deviation of the total lumbar spine was 43.0% ± 11.3%. At univariable analysis, spinal FF showed significant negative correlation with BASDAI (β = -0.474, p = 0.002) and ASDAS with C-reactive protein (ASDAS-CRP; β = -0.478, p = 0.002) and a significant positive correlation with AS disease duration (β = 0.440, p = 0.001). After adjusting for patient age, sex, and total mSASSS score, spinal FF remained significantly negatively correlated with BASDAI (β = -0.543, p < 0.001), ASDAS-CRP (β = -0.568, p < 0.001), and ASDAS with erythrocyte sedimentation rate (β = -0.533, p = 0.001). Spinal FF was significantly lower in patients with very high disease activity (ASDAS-CRP > 3.5) than in those with only high disease activity (2.1 ≤ ASDAS-CRP ≤ 3.5) (p = 0.010). Conclusion: Spinal FF may help assess both AS disease activity and chronicity.

Effect of Thermal Treatments on Flavonoid Contents in Domestic Soybeans (국내산 대두(Glycine max. Merr)자원의 플라보노이드 대사체 동정 및 열처리 효과)

  • Shin, Jae-Hyeong;Kim, Heon-Woong;Lee, Min-Ki;Jang, Ga-Hee;Lee, Sung-Hyen;Jang, Hwan-Hee;Hwang, Yu-Jin;Park, Keum-Yong;Song, Beom-Heon;Kim, Jung-Bong
    • Korean Journal of Environmental Agriculture
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    • v.34 no.2
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    • pp.105-110
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    • 2015
  • BACKGROUND: Soy isoflavones, structurally similar to endogenous estrogens, may affect human body through both hormonally mediated and non-hormonally related mechanisms. Heat processing could change chemical compositions. The effects of different thermal processes, boiling and HTHP(high temperature and high pressure) on the composition of isoflavone compounds and total amount of domestic soybeans were investigated in this study. METHOD AND RESULTS: Three different kinds of soybean samples were collected from RDA-Genebank. The samples were extracted using methanol, distilled water, and formic acid based solvent. Also the same solvents were used for mobile phase in UPLC/ToF/MS. All of the isoflavone compounds were analyzed based on the aglycone type of external standard for quantification. The standard calibration curve presented linearity with the correlation coefficient R2 > 0.98, analysed from 1 to 50 ppm concentration. The total isoflavone contents does not change by treatment within the same breed. While "boiling" and "HTHP" processes tend to increase the contents of aglycone and ${beta}$-glucosides, "fresh" soybeans retained the high concentration of malonylglucosides. CONCLUSION: These results have to be considered while developing an effective functional food, from the health while point of view using soybeans.