• Title/Summary/Keyword: stable points

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Effect of Geranti Bio-Ge Yeast, a Dried Yeast Containing Biogermanium, on the Production of Antibodies by B Cells (B 세포의 항체 생산에 대한 게란티 바이오-게르마늄 효모의 영향)

  • Joo, Seong-Soo;Won, Tae-Joon;Lee, Yong-Jin;Kim, Min-Jung;Park, So-Young;Lee, Sung-Hee;Lee, Do-Ik;Hwang, Kwang-Woo
    • IMMUNE NETWORK
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    • v.6 no.2
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    • pp.86-92
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    • 2006
  • Background: Germanium compounds are increased to use in nutrient foods and medicines in terms of antibiotics to microbes, anticancer, modulation of immune system and neutralizing heavy metal toxins. Geranti Bio-Ge Yeast, containing stable organic germanium and bound to the yeast protein was developed by Geranti Pharm. LTD. and the modulation effect in the immune system was examined in vivo and in vitro. Methods: The compound, Geranti Bio-Ge Yeast, was fed to female Balb/c mice (each group has 10 mice) for 4 weeks and the yeast powder and steamed red ginseng powder were used as control during the same feeding time points. During 4 weeks there was no symptom to be considered, and after 4 weeks feeding all mice were sacrificed to check the changes of related immune cells and subsidiary responses (i.e. cell counting, FACS, MTT, LDH, PFC assay). Results: In pre-post comparison, B cell population was increased in the group of Geranti Bio-Ge Yeast in a dose dependent manner (100 to 800 mg/kg). However, the population of T cell, dendritic cell and macrophage was not comparably changed in all doses. The ability of cytokine production and proliferation was almost same level as shown in control group. In contrast, PFC assay informed that the compound increase the antibody production ability when fed over 200 mg/kg implying that the increase of PFC number might be due to the increase of B cells. Conclusion: Over the entire study, we concluded that the compound, Geranti Bio-Ge Yeast has better potential in immune response in terms of B cell proliferation than that of positive control, red ginseng, and the compound can be one of the future candidates for a new supplementary source improving immune system activity.

Efficacy of Ilizarov External Fixation and Autologous Bone Grafting for Performing Arthrodesis on the Ankle Arthropathy with Risk Factors (불유합의 위험 인자를 가진 족관절 병변에 시행한 족관절 유합술로서 Ilizarov 외고정 기구 장착술 및 자가골 이식술의 유용성)

  • Lee, Yong-Sik;Nam, Il-Hyun;Lee, Tae-Hun;Ahn, Gil-Yeong;Lee, Yeong-Hyeon;Lee, Hee-Hyung;Hwang, Sung-Hyun
    • Journal of Korean Foot and Ankle Society
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    • v.23 no.4
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    • pp.189-195
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    • 2019
  • Purpose: The aim of this study is to evaluate if the Ilizarov external fixation procedure with axial compression can help to obtain fusion across the ankle joint in patients with a high risk of nonunion. Materials and Methods: From January 2006 to December 2015, the study reviewed 17 patients who underwent ankle arthropathy with a high risk of nonunion and who underwent ankle fusion using the Ilizarov external fixator with axial compression and auto bone grafting. After the lateral surface of the ankle joint was exposed through a lateral trans-fibular approach, massive removal of the articular cartilage and excision of any loose or avascular bone were done. With the cortical bone harvested from the pelvis as corticocancellous bone blocks, we inserted the two cortical blocks longitudinally into the anterior and posterior part of the free ankle space from lateral to medial to make the rectangular chamber to fill the cancellous bones. After the Ilizarov external fixator was equipped, we tightened the frame by 5 mm to compress the bone graft space. We accessed the American Orthopaedic Foot and Ankle Society (AOFAS) AnkleHindfoot score both preoperatively and postoperatively. Results: The average age at the time of operation was 63.4 years (range, 47~78 years). The mean frame time was 17.4 weeks (range, 15~23 weeks). The average follow-up period was 3.7 years (range, 2~6 years). Osseous fusion was obtained in 15 patients (88.2%). There were two stable pseudarthroses among the rheumatoid arthritis patients, and we continued their follow-up. The mean AOFAS AnkleHindfoot score improved from 48.5 to 73.7 points. Conclusion: Ankle arthrodesis using the Ilizarov external fixation with axial compression and auto bone grafting on the ankle arthropathy that had difficult conditions to achieve union is considered one of the useful methods with a correspondingly low incidence of complications.

A COMPARATIVE STUDY OF THE 1-PIECE AND 2-PIECE CONICAL ABUTMENT JOINT: THE STRENGTH AND THE FATIGUE RESISTANCE

  • Kwon, Taek-Ka;Yang, Jae-Ho;Kim, Sung-Hun;Han, Jung-Suk;Lee, Jai-Bong
    • The Journal of Korean Academy of Prosthodontics
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    • v.45 no.6
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    • pp.780-786
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    • 2007
  • Statement of problem. The performance and maintenance of implant-supported prostheses are primarily dependent upon load transmission both at the bone-to-implant interface and within the implant-abutment-prosthesis complex. The design of the interface between components has been shown to have a profound influence on the stability of screw joints. Purpose. The Purpose of this study was to compare the strength and the fatigue resistance of 1-piece and 2-piece abutment connected to oral implant, utilizing an internal conical interface. Material and methods. Twenty $Implatium^{(R)}$ tapered implants were embedded to the top of the fixture in acrylic resin blocks. Ten $Combi^{(R)}$(1-piece) and $Dual^{(R)}$(2-piece) abutments of the same dimension were assembled to the implant, respectively. The assembled units were mounted in a testing machine. A load was applied perpendicular to the long axis of the assemblies and the loading points was at the distance of 7mm from the block surface. Half of 1-piece and 2-piece abutment-implant units were tested for the evaluation of the bending strength, and the others were cyclically loaded for the evaluation of the fatigue resistance until plastic deformation occurred. Nonparametric statistical analysis was performed for the results. Results. Mean plastic and maximum bending moment were $1,900{\pm}18Nmm,\;3,609{\pm}106Nmm$ for the 1-piece abutment, and $1,250{\pm}31Nmm,\;2,688{\pm}166Nmm$ for the 2-piece abutment, respectively. Mean cycles and standard deviation when implant-abutment joint showed a first plastic deformation were $238,610{\pm}44,891$. cycles for the 1-piece abutment and $9,476{\pm}3,541$ cycles for the 2-piece abutment. A 1-piece abutment showed significantly higher value than a 2-piece abutment in the first plastic bending moment (p<.05), maximum bending moment (p<.05) and fatigue strength (p<.05). Conclusion. Both 1-piece and 2-piece conical abutment had high strength and fatigue resistance and this suggests long-term durability without mechanical complication. However, the 1-piece conical abutment was more stable than the 2-piece conical abutment in the strength and the fatigue resistance.

Design and Implementation of Geographical Handoff System Using GPS Information (GPS정보를 이용한 위치기반 핸드오프 시스템의 설계 및 구현)

  • Han, Seung-Ho;Yang, Seung-Chur;Kim, Jong-Deok
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.35 no.1A
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    • pp.33-43
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    • 2010
  • Recently, users want to use real-time multimedia services, such as internet, VoIP, etc., using their IEEE 802.11 wireless lan mobile stations. In order to provide such services, a handoff among access points is essential to support the mobility of a node, in such an wide area. However, the legacy handoff methods of IEEE 802.11 technology are easy to lose connections. Also, the recognition of a disconnection and channel re-searching time make the major delay of the next AP to connect. In addition, because IEEE 802.11 decides the selection of an AP depending only on received signal strength, regardless of a node direction, position, etc., it cannot guarantee a stable bandwidth for communication. Therefore, in order to provide a real-time multimedia service, a node must reduce the disconnection time and needs an appropriate algorithm to support a sufficient communication bandwidth. In this paper, we suggest an algorithm which predicts a handoff point of a moving node by using GPS location information, and guarantees a high transmission bandwidth according to the signal strength and the distance. We implemented the suggested algorithm, and confirmed the superiority of our algorithm by reducing around 3.7ms of the layer-2 disconnection time, and guaranteed 24.8% of the communication bandwidth.

Characteristic of Fish Community in the Stream Flowing into the Han River in Seoul, Korea (서울시 한강으로 유입되는 하천의 어류 군집 특성)

  • Byeon, Hwa-Keun
    • Korean Journal of Environment and Ecology
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    • v.32 no.3
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    • pp.261-273
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    • 2018
  • This study investigated the characteristics of fish communities in the streams flowing into the Han river in Seoul in May 2016 through April 2017. The investigated streams were Ui stream, Danghyeon stream, Cheonggye stream, Yangjae stream, Mokgam stream, Dorim stream, and Hongje stream, which were restored to their natural form. We collected 41 species of 10 families using skimming nets and cast nets from 21 points during the investigation period. There were 7 Korean endemic species, or 17.1% in collected species, such as Acheilognathus yamatsutae, Acheilognathus gracilis, Scrcocheilichthys nigripinnis morii, Squalidus japonicus coreanus, Zacco koreanus, Coreoperca herzi, and Odontobutis interruta. There were 5 (12.2%) exotic species: Cyprinus carpio (fancy type), Carassius auratus (goldfish), Carassius cuvieri, Lepomis macrochirus, and Micropterus salmoides. The dominant species were Zacco platypus, Carassius auratus, Acheilognathus lanceolatus, Acheilognathus gracilis, and Oryzias sinensis. The Yangjae stream showed more stable fish community than other streams as it showed higher species diversity, and evenness and richness indices. Regarding the fish tolerance guild according to water quality, there were 3 (7.3%) sensitive species, 16 (39.0%) intermediate species, and 22 (56.7%) tolerant species. Twelve (29.3%) were insectivore species, 23 (56.1%) were omnivore species, and 6 (14.6%) were carnivore species, indicating the dominating presence of omnivore fish species.

Earmarking the Areas in Which Wildlife Exist as "Ecologically Connected Areas Requiring Preferential Preservation" (야생동물 출현지점의 토지이용형태를 고려한 "우선보전연결구간" 선정)

  • SaGong, Jung-Hee;Ra, Jung-Hwa;Chung, Ok-Sik
    • Journal of the Korean Institute of Landscape Architecture
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    • v.39 no.1
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    • pp.106-116
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    • 2011
  • The purpose of this study was to find ecologically stable areas involving the locations in which wildlife exist, and to earmark those places as "ecologically connected areas requiring preferential preservation," and through that, to reduce the perils that may occur due to urban development or road construction. The processes and the results of this study were as follows: 1. Selecting the spots in which wildlife may exist: The total study areas were analyzed by eight ecological indexes and then a total of 500 locations in study areas were selected. 2. Sorting the locations in which mammals exist: We surveyed each one of the 500 locations twice, and then confirmed that we found mammals at 492 of the 500 locations and analyzed 264 locations that the number of existing mammals was above average. 3. Analyzing the 264 locations with two indexes, the number and the frequency of the land use types: 5~7 types of land use were suitable. The types were forest, rice field, farm, river, and meadow, excluding building and road. 4. Selecting the locations that meet the above conditions: We sorted 89 locations and earmarked these points as "ecologically connected areas requiring preferential preservation" in order to expect continued existence of wildlife.

A Study on Dental Hygiene Students' Consciousness about Course Education and their Occupation (치위생과 학생들의 전공교육 및 직업관에 대한 의식 조사 연구)

  • Jung, Jae-Yeon;Choi, Jeong-Iee
    • Journal of the Korean Society of School Health
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    • v.13 no.1
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    • pp.131-145
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    • 2000
  • For the purpose of strengthening Dental Hygiene students' confidence and motivation in the Dental Hygiene Department and helping construct proper professionalism, survey on Dental Hygiene students' consciousness of attitude to and satisfaction of the course, career plan and occupation mind set was carried out. 530 three year students in 8 Dental Hygiene academies in Seoul and Kyonggi province were questioned. The results of the survery are as follows:. 1. Dental Hygiene students' motives consisted primarily of employment and a desire for professionalism 25% of them entered the course after one failure in the entrance examination and 17% had family members engaging in the dentistry field 84%, the largest portion, were from an academic high school. 24% had some knowledge of Dental Hygiene, which they had acquired from seniors, friends, and teachers. 2. Patient care and treatment assistance related matters were not considered important in the course. The weak points of the course turned out to be education in computers and foreign languages, but the weakest was the ability of patient care during clinical training. 53% had experiences had thought of changing their major while in the course because it didn't match their aptitude and interest. 3. As for a career after graduation, 49% worried about it Most students wanted to work at a dental hospital or general hospital, The most favored duty was coordination or reception or oral disease preventive work. They wanted to work untill they had a stable living. 68% answered they would get a job at an oral clinic and 70% said they would continue studying for self-realization. 4. Satisfaction with the major was high in students whose aptitude and interest matched the course, who had background knowledge of the major, and who. didn't think of changing the major but would continue studying resulting in statistically slight difference(p<0.001). As to satisfaction with the faculties, it was high in the students whose aptitude and interest matched the major and who didn't think about a career after graduation showing a slight difference(p<05, p<0l). As for satisfaction with clinical training, students whose aptitude and interest matched the major and who didn't consider changing the major answered positively showing a statistically slight difference(p<.001, p<.01). As to satisfaction with the course, it was high in the students who entered with aptitude and interest, who had preliminary knowledge, who didn't consider changing the major, and who didn't think about a career after graduation showing a statistically slight difference(p<.001, p<.05). 5. Occupation mind-set was positive for students who entered with interest and aptitude, who had preliminary knowledge, and who had not considered changing the major showing a statistically slight difference(P<.001). The higher the satisfaction with the major, faculty and clinical training was, the more positive the occupation mind-set was(p<.001).

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A Priority Based Multipath Routing Mechanism in the Tactical Backbone Network (전술 백본망에서 우선순위를 고려한 다중 경로 라우팅 방안)

  • Kim, Yongsin;Shin, Sang-heon;Kim, Younghan
    • Journal of KIISE
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    • v.42 no.8
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    • pp.1057-1064
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    • 2015
  • The tactical network is system based on wireless networking technologies that ties together surveillance reconnaissance systems, precision strike systems and command and control systems. Several alternative paths exist in the network because it is connected as a grid to improve its survivability. In addition, the network topology changes frequently as forces and combatants change their network access points while conducting operations. However, most Internet routing standards have been designed for use in stable backbone networks. Therefore, tactical networks may exhibit a deterioration in performance when these standards are implemented. In this paper, we propose Priority based Multi-Path routing with Local Optimization(PMPLO) for a tactical backbone network. The PMPLO separately manages the global and local metrics. The global metric propagates to other routers through the use of a routing protocol, and it is used for a multi-path configuration that is guaranteed to be loop free. The local metric reflects the link utilization that is used to find an alternate path when congestion occurs, and it is managed internally only within each router. It also produces traffic that has a high priority privilege when choosing the optimal path. Finally, we conducted a simulation to verify that the PMPLO can effectively distribute the user traffic among available routers.

A safe, stable, and convenient three-dimensional device for high Le Fort I osteotomy

  • Sugahara, Keisuke;Koyachi, Masahide;Odaka, Kento;Matsunaga, Satoru;Katakura, Akira
    • Maxillofacial Plastic and Reconstructive Surgery
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    • v.42
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    • pp.32.1-32.4
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    • 2020
  • Background: Le Fort I osteotomy is a highly effective treatment for skeletal jaw deformities and is commonly performed. High Le Fort I osteotomy is a modified surgical procedure performed for improving the depression of the cheeks by setting the osteotomy higher than the conventional Le Fort I osteotomy. Developments in three-dimensional (3D) technology have popularized the use of 3D printers in various institutions, especially in orthognathic surgeries. In this study, we report a safe and inexpensive method of performing a high Le Fort I osteotomy using a novel 3D device and piezosurgery, which prevent tooth root injury without disturbing the operation field for patients with a short midface and long tooth roots. Results: A 17-year-old woman presented with facial asymmetry, mandibular protrusion, a short midface, and long tooth roots. We planned high Le Fort I osteotomy and bilateral sagittal split ramus osteotomy. Prevention of damage to the roots of the teeth and the infraorbital nerve and accurate determination of the posterior osteotomy line were crucial for clinical success. Le Fort I osteotomy using 3D devices has been reported previously but were particularly large in size for this case. Additionally, setting the fixing screw of the device was difficult, because of the risk of damage to the roots of the teeth. Therefore, a different surgical technique, other than the conventional Le Fort I osteotomy and 3D device, was required. The left and right parts of the 3D device were fabricated separately, to prevent any interference in the surgical field. Further, the 3D device was designed to accurately cover the bone surface from the piriform aperture to the infra-zygomatic crest with two fixation points (the anterior nasal spine and the piriform aperture), which ensured stabilization of the 3D device. The device is thin and does not interfere with the surgical field. Safe and accurate surgical performance is possible using this device and piezosurgery. The roots of the teeth and the infraorbital nerve were unharmed during the surgery. Conclusions: This device is considerably smaller than conventional devices and is a simple, low-cost, and efficient method for performing accurate high Le Fort I osteotomy.

Preliminary Evaluation of Domestic Applicability of Deep Borehole Disposal System (심부시추공 처분시스템의 국내적용 가능성 예비 평가)

  • Lee, Jongyoul;Lee, Minsoo;Choi, Heuijoo;Kim, Kyungsu;Cho, Dongkeun
    • Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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    • v.16 no.4
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    • pp.491-505
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    • 2018
  • As an alternative to deep geological disposal technology, which is considered as a reference concept, the domestic applicability of deep borehole disposal technology for high level radioactive waste, including spent fuel, has been preliminarily evaluated. Usually, the environment of deep borehole disposal, at a depth of 3 to 5 km, has more stable geological and geo-hydrological conditions. For this purpose, the characteristics of rock distribution in the domestic area were analyzed and drilling and investigation technologies for deep boreholes with large diameter were evaluated. Based on the results of these analyses, design criteria and requirements for the deep borehole disposal system were reviewed, and preliminary reference concept for a deep borehole disposal system, including disposal container and sealing system meeting the criteria and requirements, was developed. Subsequently, various performance assessments, including thermal stability analysis of the system and simulation of the disposal process, were performed in a 3D graphic disposal environment. With these analysis results, the preliminary evaluation of the domestic applicability of the deep borehole disposal system was performed from various points of view. In summary, due to disposal depth and simplicity, the deep borehole disposal system should bring many safety and economic benefits. However, to reduce uncertainty and to obtain the assent of the regulatory authority, an in-situ demonstration of this technology should be carried out. The current results can be used as input to establish a national high-level radioactive waste management policy. In addition, they may be provided as basic information necessary for stakeholders interested in deep borehole disposal technology.