• 한국농림기상학회지
• /
• 제23권4호
• /
• pp.356-365
• /
• 2021

농업기상재해 조기경보 서비스를 전국으로 확대하기 위해서는 각 지역별로 고유한 지리적, 농업환경적 특성에 대한 연구가 필요하다. 그리고 그에 적합한 전산 환경을 개발하는 것은 연구 대상 지역의 많은 농가에게 다양한 작물과 품종에 대한 서비스를 가능하게 하는 중요한 요소이다. 특히 확장성 있는 전산 환경의 설계는 서비스 영역이 확대되면서 전산 환경의 규모가 증가하게 되므로 농업 기상 서비스 품질에 상당한 영향을 미칠 수 있다. 이 연구의 목적은 각 지역별로 분산되어 서비스를 제공하고 있는 현재의 전산 구성에 대한 문제를 도출하고 그 해결책을 모색하는 것이다. 약 1년간 실험 운영을 통해 자체 평가한 결과 지역별로 분산된 조기경보서비스 시스템을 통합하면 중복 연산을 줄이고, 데이터의 효율적 저장과 종합적인 관리가 가능할 것으로 확인되었다. 이는 서비스 지역이 전국 규모로 확대되는 상황에서도 보다 안정적인 조기경보 서비스가 가능함을 의미한다. 이 연구를 통해 개별 농가에 대해 보다 향상된 품질의 서비스가 가능할 것으로 기대한다.

• Pediatric Gastroenterology, Hepatology & Nutrition
• /
• 제25권1호
• /
• pp.30-40
• /
• 2022

Purpose: Pediatric acute appendicitis has a stable incidence rate in Western countries with an annual change of -0.36%. However, a sharp increase was observed in the Asian region. The Indonesian Health Department reveals appendicitis as the fourth most infectious disease, with more than 64,000 patients annually. Hence, there is an urgent need to identify and evaluate the risk factors and diagnostic modalities for accurate diagnosis and early treatment. This study also clarifies the usage of pediatric appendicitis score (PAS) for children <5 years of age. Methods: The current study employed a cross-sectional design with purposive sampling through demographic and PAS questionnaires with ultrasound sonography (USG) results. The analysis was performed using the chi-square and Mann-Whitney tests and logistic regression. Results: This study included 21 qualified patients with an average age of 6.76±4.679 years, weighing 21.72±10.437 kg, and who had been hospitalized for 4.24±1.513 days in Siloam Teaching Hospital. Compared to the surgical gold standard, PAS and USG have moderate sensitivity and specificity. Bodyweight and stay duration were significant for appendicitis (p<0.05); however, all were confounders in the multivariate regression analysis. Incidentally, a risk prediction model was generated with an area under the curve of 72.73%, sensitivity of 100.0%, specificity of 54.5%, and a cut-off value of 151. Conclusion: PAS outperforms USG in the sensitivity of diagnosing appendicitis, whereas USG outperforms PAS in terms of specificity. This study demonstrates the use of PAS in children under 5 years old. Meanwhile, no risk factors were significant in multivariate pediatric acute appendicitis risk factors.

• 한국전자통신학회논문지
• /
• 제16권6호
• /
• pp.1339-1348
• /
• 2021

재생에너지 출력제한은 송전용량과 전력계통 안정성 부족을 포함하여 다양한 원인이 있다. 제주도 지역에서는 태양광 및 풍력 발전설비의 증가로 이미 전력수요에 비해 공급이 많아지는 사례가 자주 발생하고 있으며, 이에 따라 풍력발전의 출력제한 횟수가 증가하고 있다. 본 연구에서는 제주도 전력공급의 핵심 역할을 담당하고 있는 HVDC(고전압 직류)와 BESS(배터리 에너지 저장장치) 설비를 활용하여 재생에너지의 효과적인 수용과 전력계통의 안정적 운영 방향을 찾는 것이다. 그리고 이 논문에서는 각 설비들의 실질적인 운전방안을 제시하고 향후 태양광 및 풍력 발전설비의 확대에 따른 육지 전력계통의 운영 방향을 제안한다.

• Journal of Microbiology and Biotechnology
• /
• 제32권1호
• /
• pp.46-55
• /
• 2022

Clostridioides difficile infection (CDI) is a significant cause of hospital-acquired and antibiotic-mediated intestinal diseases and is a growing global public health concern. Overuse of antibiotics and their effect on normal intestinal flora has increased the incidence and severity of infections. Thus, the development of new, effective, and safe treatment options is a high priority. Here, we report a new probiotic strain, Bacillus amyloliquefaciens (BA PMC-80), and its in vitro/in vivo anti-C. difficile effect as a prospective novel candidate for replacing conventional antibiotics. BA PMC-80 showed a significant anti-C. difficile effect in coculture assay, and its cell-free supernatant (CFS) also exhibited a considerable anti-C. difficile effect with an 89.06 ㎍/ml 50% minimal inhibitory concentration (MIC) in broth microdilution assay. The CFS was stable and equally functional under different pHs, heat, and proteinase treatments. It also exhibited a high sensitivity against current antibiotics and no toxicity in subchronic toxicity testing in hamsters. Finally, BA PMC-80 showed a moderate effect in a hamster CDI model with reduced infection severity and delayed death. However, further studies are required to optimize the treatment condition of the hamster CDI model for better efficacy and identify the antimicrobial compound produced by BA PMC-80.

• 대한의용생체공학회:의공학회지
• /
• 제43권5호
• /
• pp.319-330
• /
• 2022

In this study, the optimal driving frequency was derived through finite element analysis (FEA) to optimize the developed piezoelectric ultrasonic medical devices(PUMD) for bone surgery. The core of the PUMD is the piezoelectric ceramic (PZT), which is a vibrator that generates vibration energy. The piezoelectric ceramic shows the maximum current value with respect to the input voltage at the resonance frequency, which generates the maximum mechanical vibration. In the past, various studies have been conducted related to the analysis of PUMD, but most of the research so far has been limited to free vibration analysis. However, in order to derive the accurate resonant frequency, the initial stress generated by bolt tightening in the bolt-clamped Langevin type transducer (BLT) must be considered. In this study, after designing a PUMD, the driving performance according to the bolt tightening value was analyzed through FEA, and this was experimentally verified. First, the resonance mode and frequency response were confirmed through modal and harmonic analysis at 20-40 kHz, which is known as the optimal driving frequency band of PUMD for bone surgery. In addition, the design of the PUMD was confirmed by checking the mechanical behavior of the tip and the piezoelectric ceramic at the resonant frequency. Consequentially, the characteristic evaluation was performed, and it was confirmed that the resonant frequency result derived through the FEA was reasonable. Through this study, we presented a more rational FEA method than before for BLT transducers. We expect that this will shorten the time and cost of developing a PUMD, and will enable the development of more stable and high-quality products.

• Current Optics and Photonics
• /
• 제6권5호
• /
• pp.497-505
• /
• 2022

Topological photonic nanocavities are considered to possess outstanding optical performance, and provide new platforms for realizing strong interaction between light and matter, due to their robustness to impurities and defects. Here hybrid plasmonic topological photonic nanocavities are proposed, by embedding various plasmon nanoantennas such as gold nanospheres, cylinders, and rectangles in a topological photonic crystal corner-state nanocavity. The maximum quality factor Q and minimum effective mode volume V_eff of these hybrid nanocavities can reach the order of 10⁴ and 10^-4 (𝜆/n)³ respectively, and the high figures of merit Q/V_eff for all of these hybrid nanocavites are stable and on the order of 10⁵ (𝜆/n)^-3. The relative positions of the plasmon nanoantennas will influence the coupling strength between the plasmon structures and the topological nanocavity. The hybrid nanocavity with gold nanospheres possesses much higher Q, but relatively large V_eff. The presence of a gold rectangular structure can confine more electromagnetic energy within a smaller space, since its V_eff is smallest, although Q is lowest among these structures. This work provides an outstanding platform for cavity quantum electrodynamics and has a wide range of applications in topological quantum light sources, such as single-photon sources and nanolasers.

• The Plant Pathology Journal
• /
• 제38권6호
• /
• pp.572-582
• /
• 2022

Sheath blight disease caused by the necrotrophic, soilborne pathogen Rhizoctonia solani Kuhn, is the global threat to rice production. Lack of reliable stable resistance sources in rice germplasm pool for sheath blight has made resistance breeding a very difficult task. In the current study, 101 rice landraces were screened against R. solani under artificial epiphytotics and identified six moderately resistant landraces, Jigguvaratiga, Honasu, Jeer Sali, Jeeraga-2, BiliKagga, and Medini Sannabatta with relative lesion height (RLH) range of 21-30%. Landrace Jigguvaratiga with consistent and better level of resistance (21% RLH) than resistant check Tetep (RLH 28%) was used to develop mapping population. DNA markers associated with ShB resistance were identified in F₂ mapping population developed from Jigguvaratiga × BPT5204 (susceptible variety) using bulk segregant analysis. Among 56 parental polymorphic markers, RM5556, RM6208, and RM7 were polymorphic between the bulks. Single marker analysis indicated the significant association of ShB with RM5556 and RM6208 with phenotypic variance (R²) of 28.29 and 20.06%, respectively. Co-segregation analysis confirmed the strong association of RM5556 and RM6208 located on chromosome 8 for ShB trait. This is the first report on association of RM6208 marker for ShB resistance. In silico analysis revealed that RM6208 loci resides the stearoyl ACP desaturases protein, which is involved in defense mechanism against plant pathogens. RM5556 loci resides a protein, with unknown function. The putative candidate genes or quantitative trait locus harbouring at the marker interval of RM5556 and RM6208 can be further used to develop ShB resistant varieties using molecular breeding approaches.

• Archives of Plastic Surgery
• /
• 제48권6호
• /
• pp.703-713
• /
• 2021

The field of vascularized composite allografts (VCAs) has undergone significant advancement in recent decades, and VCAs are increasingly common and accepted in the clinical setting, bringing hope of functional recovery to patients with debilitating injuries. A major obstacle facing the widespread application of VCAs is the side effect profile associated with the current immunosuppressive regimen, which can cause a wide array of complications such as infection, malignancy, and even death. Significant concerns remain regarding whether the treatment outweighs the risk. The potential solution to this dilemma would be achieving VCA tolerance, which would allow recipients to receive allografts without significant immunosuppression and its sequelae. Promising tolerance protocols are being studied in kidney transplantation; four major trials have attempted to withdraw immunosuppressive treatment with various successes. The common theme in all four trials is the use of radiation treatment and donor cell transplantation. The knowledge gained from these trials can provide valuable insight into the development of a VCA tolerance protocol. Despite similarities, VCAs present additional barriers compared to kidney allografts regarding tolerance induction. VCA donors are likely to be deceased, which limits the time for significant pre-conditioning. VCA donors are also more likely to be human leukocyte antigen-mismatched, which means that tolerance must be induced across major immunological barriers. This review also explores adjunct therapies studied in large animal models that could be the missing element in establishing a safe and stable tolerance induction method.

• 기록학연구
• /
• 제72호
• /
• pp.5-32
• /
• 2022

민간에서 시민이 자신의 기록을 수집하거나 아카이빙하고 이를 활용하도록 하는 것은 시민사회에서 시민이 누려야 하는 정당한 권리며, 국가는 이러한 시민의 기록활동을 적절히 지원할 수 있는 체계를 갖추어야 한다. 그러나 현재 국가기록관리 체계는 민간기록관리를 지원하기 위한 공적 지원 체계를 가지고 있지 못하고 지원 대상에서 민간기록을 배제하고 있다. 민간 기록은 한번 소실되거나 훼손될 경우, 복원이나 회복 불가능하다는 점을 고려할 때 국가적 관심과 지원이 필요한 것은 분명하다. 본 연구는 민간기록에 대한 제도적 지원의 필요성을 논하고 지원정책의 방향성을 크게 두 가지, 시민기록문화의 활성화와 진흥을 위한 안정적 지원, 그리고 민간기록의 안정적 관리 보존을 위한 지역 내 민간기록수집 및 보존을 위한 조직과 물리적 공간의 지원이라고 파악하고, 이를 실천하기 위해 구체적으로 민간기록관리의 개념적 범주와 현황, 그리고 민간기록관리 정책 수립 시 고려가 필요한 민간기록관리의 특징에 대해 살펴보았다.

• 산업진흥연구
• /
• 제7권2호
• /
• pp.1-13
• /
• 2022

본 연구는 대구 지역사회서비스투자사업을 제공하는 기관별 현황과 성과를 통해 효율성을 살펴보고 각 기관의 효율적인 운영을 위한 방향을 모색하는데 그 목적이 있다. 지역사회서비스투자사업의 추진 목적에 부합되는 관리 실태를 점검하여 효율적이고 효과적인 사업추진을 도모하기 위하여 수요자에게 필요한 체계적인 서비스 제공 및 품질개선, 환경개선을 위해서는 서비스 제공기관의 효율성 분석을 통해 정확한 상황과 그에 대한 문제점을 파악하고, 지역 특성에 맞는 프로그램을 개발하고 적극적인 서비스 관리가 필요하다. 구체적으로 각 기관의 정보를 바탕으로 효율성을 측정하고 이를 지방자치단체 간 비교 분석함으로써 보다 안정적이고 지속가능한 지역사회서비스의 제공방향을 모색하는 것이다. 이를 위해 DEA(data envelopment analysis, 자료포락분석) 방법을 활용하여 각각의 기관을 효율성을 분석하고 지자체별로 비교하여 효율적 운영을 위한 목표와 정책적 함의를 제시하는데 그 의의가 있다.