• 제목/요약/키워드: stabilizers

검색결과 277건 처리시간 0.036초

무전해 니켈 도금용액에 사용되는 안정제의 도금피막 특성에 미치는 영향 (The Effect of Stabilizers on the Characteristics of Deposit in the Electroless Nikel Plating)

  • 이홍기;손성호;전준미;구석본;허진영
    • 한국표면공학회지
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    • 제37권6호
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    • pp.335-343
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    • 2004
  • Bath stabilizers in the electroless nickel(EN) plating solution are known to prevent sudden bath decomposition and extend its lifetime. Further, every stabilizer has a different role and function in EN solution and it influences the surface structure. In this study, the effects of various stabilizers on the deposition rate, surface morphology, deposition content of phosphor and hardness were investigated.

Metoclopramide의 생체내대사(生體內代謝)에 미치는 안정제(安定劑)의 영향에 관한 실험적(實驗的) 연구(硏究) (Experimental Studies on the Metabolism of Metoclopramide: The Effects of a Few Stabilizers)

  • 지웅길
    • Journal of Pharmaceutical Investigation
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    • 제9권2호
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    • pp.11-21
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    • 1979
  • It has been reported from our department that a few agents, such as $K_2S_2O_5,\;NaHSO_3,$ nicotinamide have a marked stabilizing effect in vitro on metoclopramide which is relatively unstable compound. In order to study the effect of these stabilizers on the action of metoclopramide in vitro, the fate of this compound combined with $K_2S_2O_5,\;NaHSO_3$ and nicotinamide, respectively, was studied and furthermore, the change of the biological activity of metoclopramide due to these stabilizers was studied by using the isolated stomach strip of rat. The blood concentration of metoclopramide was measured by using Bakke's method at the various time after intravenous injection of the mixed metoclopramide solution with the stabilizers. In order to study the excretion of the drug, rabbits were anesthesized and catheterized into bladder for withdrawal of urine. After intravenous injection of the mixed metoclopramide solution, urine was collected for 5 hours and the conjugated forms of metoclopramide as well as the free form were determined by using Arita's method. In the biological study of the metoclopramide combined with stabilizers, the contractability of the isolated rat stomach strip was observed by using polygraph recorder. The results were following: 1. When metoclopramide was administered with nicotinamide as stabilizer, the blood concentration of the unchanged from and the rate of the clearance of this compound were very similar to that of metoclopramide alone. On the other hand, other stabilizers, $K_2S_2O_5\;and\;NaHSO_3$, brought about 40% decrease in blood concentration of the unchanged form at 15 min after intravenous injection however, the rate of clearance of metoclopramide with $K_2S_2O_5\;or\;NaHSO_3$ was very slow. 2. In the case of urinary excretion, the excretory pattern of the metabolites of metoclopramide with $NaHSO_3$ or nicotinamide was very similar to that of metoclopramide alone. But metodopramide plus $K_2S_2O_5$ group showed the maked depression of excretion for first 1 hour. 3. In composition of metabolites, when metoclopramide was administered with $K_2S_2O_5$ or $NaHSO_3$, the sulfonate conjugation was predominant. But the glucuronic acid conjugation was predominant in metoclopramide plus nicotinamide gronp. 4. In the experiments on the biological activity of the metoclopramide, this compound exhibited the marked contracting effect in isolatd rat stomach strip. Specially, the meetoclopramide combined with $K_2S_2O_5$ showed the strong contraction of the isolated strip, suggesting the potenciating effect of $K_2S_2O_5$ on the action of metoclopramide in the isolated strip.

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Hormon제제(製劑)의 안정성(安定性)에 관(關)한 연구(硏究)(I) 항(抗) Allergy성(性)Hormon제(劑) 및 Sulfonylurea유도체(誘導體)에 관(關)한 안정성(安定性) (Studies on the Stabilities of Hormones Combined with Some Stabilizers)

  • 김재완
    • Journal of Pharmaceutical Investigation
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    • 제1권1호
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    • pp.58-61
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    • 1971
  • Comparatives studies were made on stabilities of some hormons, used individually and combined with some stabilizers, and the following results were found. 1. The increasing order of antiallergic hormons (prednisolone, dexamethasone) to the stabilities as follows : Chlorpheniramine>Menadione>Inositol>Ascorbic acid. 2. The increasing order of sulfonylureas in as follows : Chlorpheniramine>Thiamine>Inositol>Ascorbic acid.

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Stabilization of Metals-contaminated Farmland Soil using Limestone and Steel Refining Slag

  • Lim, Jeong-Muk;You, Youngnam;Kamala-Kannan, Seralathan;Oh, Sae-Gang;Oh, Byung-Taek
    • 한국지하수토양환경학회지:지하수토양환경
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    • 제19권5호
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    • pp.1-8
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    • 2014
  • The metals contamination of farmland soil nearby abandoned metal mine was serious problem in Korea. Stabilization of contaminated soil was reported using various stabilizers. Application of limestone and steel refining slag was reported as effective stabilizers in the stabilization of metals. The batch studies confirmed that the mixture of limestone and steel refining slag was suitable for stabilization of metals in contaminated soil. The limestone and steel refining slag mixture (2 : 1 and 3 : 2) were used in column studies and it was confirmed that the stabilizers effectively stabilized heavy metals in contaminated soil. The pH of the soil was increased with the addition of stabilizers. Total leached concentration of metals from the column study was reduced 44, 17, and 93% in comparison to the control at arsenic, cadmium and copper, respectively. The sequential extraction studies showed that the exchangeable fraction was changed into carbonate bound fraction (Cd and Cu) and Fe-Mn oxide bound fraction (As). Based on the results we confirmed that 2:1 ratio of limestone and steel refining slag effectively stabilizes the heavy metals. The mixed treatment of lime stone with steel refining slag would be an effective and feasible method for controlling metals leaching in contaminated soil.

유기성 폐기물과 알칼리 안정화제가 첨가된 연안 양식장 퇴적물 조비료의 영양성분 조성 (Nutritive Quality of the Crude Organic Fertilizer Produced with Coastal Aquaculture-Ground Bottom Sediments, Organic Wastes and Alkaline Stabilizers)

  • 김정배;강창근;이근섭;박정임;이필용
    • 한국환경과학회지
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    • 제11권12호
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    • pp.1291-1298
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    • 2002
  • To utilize coastal aquaculture ground bottom sediment in which concentrations of harmful pollutants are low and organic content is high as an organic fertilizer alkaline stabilizers such as CaO, Oyster shell, Mg(OH)$_2$ were added to the bottom sediment organic additives of livestock or food wastes. Nutritive qualities of crude fertilizers were measured to examine effects of alkaline stabilizers and organic waste additions. The Mg(OH)$_2$-added crude fertilizer had significantly lower total carbon(T-C) and nitrogen(T-N) content, reflecting the dilution effect due to great amount of Mg(OH)$_2$ addition. However, the addition of oyster shell had no significant effect on the T-C and T-N content of the fertilizer. $P_2O_5$ and $K_2$O content was considerably higher in the mixed sample of aquaculture ground bottom sediments and livestock wastes than in the mixture of the sediments and food wastes, resulting from higher $P_2O_5$ and $K_2$O content in livestock wastes. Addition of Mg(OH)$_2$ increased the content of MgO In the crude fertilizer but significantly reduced the content of other nutritive elements such as $P_2O_5$, $K_2$O and CaO. Addition of oyster shell as an alkaline stabilizer seemed to have the advantage of saving time and expenses far dryness due to its role as a modulator of water content. Moreover, additions of effect Mg(OH)$_2$ decreased the concentrations of heavy metals in the fertilizer by the dilution while additions of oyster shell had no influence on heavy metal concentrations in the fertilizer.

Effect of Contralateral Hip Adduction on Activity of Lumbar Stabilizers and Pelvic Lateral Tilting During Hip Abduction in Side-Lying

  • Kim, Hyo-Uen;Kwon, Oh-Yun;Yi, Chung-Hwi;Cynn, Heon-Seock;Choi, Houng-Sik
    • 한국전문물리치료학회지
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    • 제20권4호
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    • pp.16-21
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    • 2013
  • The purpose of this study was to determine the effect of contralateral hip adduction (CHA) on the muscle activity of lumbar stabilizers and the angle of pelvic lateral tilting during hip abduction in side lying. Twenty healthy male subjects with no medical history of lower extremity or lumbar spine disorders were recruited for the study. Subjects randomly performed preferred hip abduction (PHA) and hip abduction with contralateral hip adduction in side lying. The muscle activities of the dominant side rectus abdominis, external oblique, internal oblique, quadratus lumborum, gluteus medius, and non-dominant side hip adductor longus were measured during PHA and CHA by using a surface electromyography (EMG) system. Pelvic lateral tilting motion was measured by using a three-dimensional motion analysis system. Data on EMG and pelvic motion were collected at the same time during PHA and CHA. A paired t-test was used to compare EMG activity and the angle of pelvic lateral tilting in the two exercises. The study found that the EMG activities of all muscles were more increased significantly in CHA than PHA condition. The angle of pelvic lateral tilting was more decreased significantly in CHA than PHA condition. These findings suggest that CHA could be recommended as a hip abduction exercise for activating lumbar stabilizers and decreasing compensatory pelvic lateral tilting motion.

안정제에 의한 젖산균 및 효모를 이용한 전통 안동식혜의 저장 (Effects of Stabilizer on the Storage of Andong sikhe using Lactic Acid Bacteria and Yeast)

  • 김성;손준호;조국영;손규목;최청
    • 한국식품과학회지
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    • 제30권6호
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    • pp.1394-1398
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    • 1998
  • L. bulgaricus LBS 47과 S. serevisiae SCS 5를 접종하여 전통안동식혜를 발효 후 저장하는 동안에 안정제에 의한 침전억제 효과는 Na-Alginate가 가장 우수하였다. 침전 안정제를 넣어서 관능 검사를 한 결과 균질화 하지 않은 식혜의 경우는 Na-alginate는 0.1에서 0.15% 처리했을 때 Carrageenan은 0.05% 첨가했을 때 가장 맛이 우수하였으며 식품 안정제의 종류 및 첨가 농도간의 상호 효과는 침전 안정제의 종류간에는 통계적 유의성이 없으나 첨가 농도간에는 유의성이 있었다. 식혜의 현탁안정성을 증진시킬 목적으로 안정제를 첨가하여 숙성시켰을 때 CMC, Na-alginate은 2일째 carrageenan은 비균질화 식혜는 2일에서 4일째 균질화한 식혜는 1일째 최고의 점도를 나타내었다.

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염산(鹽酸)Promazine 주사제(注射劑)의 안정화(安定化)에 관한 연구(硏究) (Study on Stabilization of Promazine Hydrochloride Injection)

  • 이완하;지웅길;양재헌
    • Journal of Pharmaceutical Investigation
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    • 제3권3호
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    • pp.5-15
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    • 1973
  • The stabilizing effect of promazine hydrochloride injectin was tested by irradiation of sun lamp(5,000 Lux) on their acid solution sealed in ampules under various stabilizers. The result of experimentation on the color change, the remaining proportion and the half life of promazine hydrochloride solution is as follows. 1. Instability of promazine hydrochloride solution is mainly caused by the sunlight and oxygen. 2. The pH range of promazine hydrochloride injection is recommended to $pH\;4.4{\sim}5.2$ 3. The decomposition of promazine hydrochloride by the sunlight is composed of pseudo zero order reaction when It maintains colorless solution. 4. The half life of 0.5% promazine hydrochloride injection was 30 hrs. under sun lamp irradiation, but it was delayed to 84 hrs. by the simple stabilizer and to 175 hrs. by compound stabilizer. 5. The stabilizing effect of promazine .hydrochloride injection adding sod. metabisulfite$(Na_2S_2O_5)$ was most excellent in various simple stabilizers and adding $Na_2S_2O_5$ to nicotinic acid, $Na_2S_2O_5$ to nicotinamide were more excellent than other compound stabilizers.

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흑미의 추출조건에 따른 안토시아닌 함량과 첨가물에 따른 색소 안전성 (Anthocyanin Content and Color Stability in Black Rice According to Different Extract Conditions and Selected Stabilizers)

  • 이혜정;장재선;최은영;김용호
    • 한국식품영양학회지
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    • 제21권2호
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    • pp.127-134
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    • 2008
  • The purpose of this study was to analyze the anthocyanin content of black rice crude extract according to different extraction methods, as well as to compare the effects of stabilizers(${\beta}$-cyclodextrin, maltodextrin) and sugars(sucrose, maltose) on anthocyanin color deterioration, which was examined at $100^{\circ}C$ for $120{\sim}180$ min. In the water extract, C3G (cyanidin-3-glucoside) was detected, 3.22 ppm and 3.29 ppm of C3G respectively. In the $60^{\circ}C$ water extract, anthocyanin color deterioration was retarded by 10% sucrose and 1% maltose and the thermal color deterioration was retarded by the additions of 1% maltodextrin and 1% ${\beta}$-cyclodextrin.

Improvement in engineering properties of subgrade soil due to stabilization and its effect on pavement response

  • Nagrale, Prashant P.;Patil, Atulya P.
    • Geomechanics and Engineering
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    • 제12권2호
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    • pp.257-267
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    • 2017
  • This paper presents laboratory investigation of stabilization of subgrade soil. One type of soil and three types of stabilizers i.e., hydrated lime, class F fly ash and polypropylene fibres are selected in the study. Atterberg limit, compaction, california bearing ratio (CBR), unconfined compressive strength and triaxial shear strength tests are conducted on unstabilized and stabilized soil for varying percentage of stabilizers to analyze the effect of stabilizers on the properties of soil. Vertical compressive strains at the top of unstabilized and stabilized subgrade soil were found out by elasto-plastic finite element analysis using commercial software ANSYS. Strategy for design of optimum pavement section was based on extension in service life (TBR) and reduction in layer thickness (LTR). Extension in service life of stabilized subgrade soil is 6.49, 4.37 and 3.26 times more due to lime, fly ash and fibre stabilization respectively. For a given service life of the pavement, there is considerable reduction in layer thicknesses due to stabilization. It helps in reduction in construction cost of pavement and saving in natural resources as well.