• 대한방사선방어학회:학술대회논문집
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• 2009.11a
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• pp.128-129
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• 2009

• Proceedings of the Plant Resources Society of Korea Conference
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• 2018.10a
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• pp.108-108
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• 2018

In this study, we evaluated the anti-cancer effect of extracts of leaves (ST-L) and branches (ST-B) from Sageretia theezans in human colorectal cancer cells. ST-L and ST-B significantly inhibited the proliferation of human colorectal cancer cells, SW480. ST-L and ST-B decreased cyclin D1 protein level through the induction of cyclin D1 proteasomal degradation via $GSK3{\beta}$-dependent threonine-286 phosphorylation of cyclin D1. In addition, ST-L and ST-B increased HO-1 protein through p38, ROS and $GSK3{\beta}$-dependent Nrf2 activation. These findings suggest that ST-L and ST-B may have great potential for the development of anti-cancer drug to treat human colorectal cancer.

• Journal of fish pathology
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• v.27 no.2
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• pp.107-114
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• 2014

For the treatments and protection of bacterial fish disease, many requirements are needed for aquatic probiotics so that they are effective in aquaculture animals but are also harmless to humans. In the present study, among 17 candidate probiotic bacteria (CPB) obtained from the edible part of the shellfish, Bacillus sp. CPB-St (CPB-St) were selected and in vitro evaluated for the possibility as a probiotic strain for the control of fish streptococcosis which frequently occurs in the olive flounder farms. CPB-St showed inhibitory effects on the growth of various fish pathogenic bacteria, Streptococcus sp., S. parauberis, S. iniae, Lactococcus garvieae and L. piscium by the double layer test ranging about 18~26 mm of clear zone. Inhibitory activity of CPB-St to Streptococcus sp. was observed 6 hours after and the growth of Streptococcus sp. was decreased to 8~55 folds in the co-culture of CPB-St with Streptococcus sp.. The safety of CPB-St to fish and survival of CPB-St in the intestine were assessed in the olive flounder, Paralichthys olivaceus. Fish mortality was not observed in artificial infection with CPB-St for 2 weeks. CPB-St was entirely excreted from the stomach and intestine 24 hours after oral injection. This results indicate that CPB-St has potential applications as a probiotic for the control of fish streptococcosis in aquaculture.

• Korean Journal of Acupuncture
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• v.28 no.1
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• pp.91-100
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• 2011

Objectives : To classify needling or moxibustion-prohibited acupoints in Emergency Formulas Worth a Thousand in Gold (EFWTG) and Supplement to the Formulas Worth a Thousand in Gold (SFWTG). Methods : We found needling or moxibustion-prohibited acupoints in EFWTG and SFWTG, then investigated the influences of needling or moxibustion-prohibited acupoints on A-B Classic of Acupuncture and Moxibustion. Results : In EFWTG, the needling-prohibited points were LI13, ST17, BL56, TE8, CV8, CV15 and GV24. Acupoints needed careful needling were LU2, ST12, KI2, KI7, TE19, GB3 and jwagak. The moxibustion-prohibited points were LU3, LU8, ST1, ST8, ST9, ST17, ST32, ST33, BL6, BL30, TE18, TE23, GB33, GB42, CV5, CV15, GV6, GV15, GV16 and GV17. Acupoints needed careful moxibustion were ST7, ST30, TE21 and GB22. In SFWTG, the needling-prohibited points were LU2, LI13, ST12, ST17, ST32, BL56, KI2, KI7, TE8, TE19, GB3, CV8, CV15, GV24 and jwagak. The moxibustion-prohibited points were LU3, LU8, ST1, ST7, ST8, ST9, ST17, ST30, ST32, ST33, BL6, BL30, TE18, TE23, GB22, GB33, GB42, CV5, CV15, GV6, GV15, GV16, GV17 and ijung. Conclusions : There were 7 needling-prohibited points, 7 acupoints needed careful needling, 20 moxibustion-prohibited points, and 4 acupoints needed careful needling in EFWTG, and 15 needling-prohibited points and 24 moxibustion-prohibited points in SFWTG. The needling or moxibustion-prohibited acupoints in A-B Classic of Acupuncture and Moxibustion had a strong influence on those in the two literatures.

• Korean Journal of Acupuncture
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• v.38 no.1
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• pp.1-7
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• 2021

Objectives : In the meridian pathway system, 5 yang meridians excluding bladder meridian pass ST12. In this study, we tried to find out why 5 yang meridians pass ST12. Methods : 15 classics of acupuncture and moxibustion literature - 『Huangdimingtangjingjixiao』, 『Zhenjiujiayijing』, 『Huangdineijingtaisu』, 『Beijiqianjinyaofang』, 『Waitaimiyaofang』, 『Ishimpo』, 『Taipingshenghuifang』, 『Tongrenshuxue-zhenjiutujing』, 『Zhenjiuzishengjing』, 『Shisijingfahui』, 『Zhenjiujuying』, 『Yixuerumen』, 『Zhenjiudacheng』, 『Leijing』, and 『Leijingtuyi』- were reviewed and compared. Results : Five yang meridians passed ST12, and large intestine meridian and triple energizer meridian were closely related to ST12 in divergent channels. Stomach meridian and gall bladder meridian were related to ST12 in meridian muscles. ST12 was related to small intestine meridian in main cure effect. ST12 is in the best position to enter the body cavity. Conclusions : It can be seen that ST12 is closely related to all internal organs through the characteristics of stomach meridian. Therefore, it is thought that ST12's various characteristics largely explains a pathway to enter the body cavity in the hand and foot three yang meridians.

• Journal of Ecology and Environment
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• v.35 no.1
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• pp.27-34
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• 2012

Typha angustifolia has ecological characteristics of clonal growth similar to Phragmites australis. The plant spreads byclonal growth and seed dispersal. In this study, for the three stands which have different settlement age at the Baksilji wetland in Korea, genetic diversity was estimated by random amplification of polymorphic DNA analysis to evaluate the change in genetic diversity of T. angustifolia during stand development in the same population. Stand (ST) 1 was the oldest and ST 4 was the youngest. ST 5 was in a small ditch out of the Baksilji. Although the ST 1, ST 2, and ST 3 did not differ significantly in vegetational or physical environment, the genetic diversity estimated according to Nei's gene diversity (h) and the Shannon index (i) increased in the order of ST 1 < ST 2 < ST 3 contrary to formative age. The genetic diversity of ST 4 was much higher than that of the other three stands. ST 4 has similar abiotic environmental conditions with slight T. angustifolia dominance, and seems to be in the early establishment stage. ST 5 differed from the other stands in vegetational and soil environments, which can result in stressful cattail conditions. Even though the ST 5 stand was not younger than the ST 4 stand, ST 5 showed the highest genetic diversity. Our results indicate that after early settlement of the T. angustifolia population, genetic diversity within the species decreased over time and that the decreasing pattern of genetic diversity within T. angustifolia stands is not likely to occur under stressful conditions.

• Journal of Physiology & Pathology in Korean Medicine
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• v.17 no.6
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• pp.1493-1499
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• 2003

This study was examined for effects of acupuncture of Chok-Samni(ST36) on the facial thermography in health subjects, The volunteers who participating in this study had taken rest for 15 mins in room temperature (19-21 ℃) before the examination and informed them what to prohibit smoking, drinking and administration of drug for the previous day, The thermography of face was taken using Digital Infrared Thermographic Imaging (D.I.T.I. : Dorex, DTI-16UT1, U.S.A.) by time interval of 35 minutes at 15 min before and 20 min after acupuncture stimulation. Thermal temperature of Yangbaek(GB14), Myon-koryo(ST3) and Chichang(ST4) was measured and compared, The results showed that acupuncture of Chok-Samni(ST36) decreased the Absolute difference of temperature between Myon-koryo(ST3) and Chichang(ST4) (p<0,05, Data were represented mean±S,E.M.(n=33)), But, acupuncture of Chok-Samni(ST36) particularly decreased the absolute difference of temperature between Yangbaek(GB14) and Chichang(ST4) and particularly decreased the absolute difference of temperature between Vangbaek(GB14) and Myon-koryo(ST3) (p<0,05, Data were represented mean±S,E.M.(n=33)). Also, it was observed that acupuncture of Chok-Samni(ST36) decreased variety of the color tone of thermographic contour line and decreased thermal distribution. The results showed that acupuncture of Chok-5amni(ST36) significantly decreased the absolute difference of temperature of partial facial surface. Hereafter, study about if acupuncture of Chok-Samni(ST36) significantly decrease the absolute difference of temperature of all the areas of facial surface is requested. Also, continued study of effects of acupuncture of other meridian on the facial thermography is requested.

• Asian-Australasian Journal of Animal Sciences
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• v.10 no.1
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• pp.20-27
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• 1997

Objectives of this study was to investigate effects of supplemental chromium (Cr) as CrP in growing pigs treated with pST. Seventy two Landrace pigs weighing average 60 kg were alloted to the three treatments during the 52-d experimental period: control (corn-soybean basal diet); pST treatment (4 mg/head/day); pST + CrP treatment (4 mg and 200 ppb/head/day). Upon termination of feeding trial weighing average 105 kg, thirty-six pigs randomly selected from each treatment were slaughtered to compare carcass traits. For the study of lipid metabolism, eighteen pigs were alloted to the same treatments. Adipose tissue samples from eighteen pigs were collected to investigate lipid metabolism. All treated samples with pST and pST + CrP showed improvements in daily weight gain, regardless of sex. Feed/gain ratio significantly improved in pigs treated with pST and pST + CrP. Dressing percentages were higher in pigs treated with pST and pST + Crp. Carcass grades were significantly higher in pigs treated with pST and pST + CrP. Lipolysis of adipose tissue measured in vitro was significantly increased in pigs treated with pST, lipogenesis in vitro showed opposite tendency. Even though the current data does not show synergistic effects on the above parameters when CrP and pST were supplied at the same time, but CrP supplementation tended to improve growth performance and carcass traits of pigs treated with pST.

• Clinical and Experimental Pediatrics
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• v.60 no.7
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• pp.221-226
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• 2017

Purpose: Escherichia coli sequence type (ST) 131, a multidrug-resistant clone causing extraintestinal infections, has rapidly become prevalent worldwide. However, the epidemiological and clinical features of pediatric infections are poorly understood. We aimed to explore the characteristics of ST131 Escherichia coli isolated from Korean children with urinary tract infections. Methods: We examined 114 uropathogenic E. coli (UPEC) isolates from children hospitalized at Chung-Ang University Hospital between 2011 and 2014. Bacterial strains were classified into STs by partial sequencing of seven housekeeping genes (adk, fumC, gyrB, icd, mdh, purA, and recA). Clinical characteristics and antimicrobial susceptibility were compared between ST131 and non-ST131 UPEC isolates. Results: Sixteen UPEC isolates (14.0%) were extended-spectrum ${\beta}-lactamase$ (ESBL)-producers; 50.0% of ESBL-producers were ST131 isolates. Of all the isolates tested, 13.2% (15 of 114) were classified as ST131. There were no statistically significant associations between ST131 and age, sex, or clinical characteristics, including fever, white blood cell counts in urine and serum, C-reactive protein, radiologic abnormalities, and clinical outcome. However, ST131 isolates showed significantly lower rates of susceptibility to cefazolin (26.7%), cefotaxime (40.0%), cefepime (40.0%), and ciprofloxacin (53.3%) than non-ST131 isolates (65.7%, 91.9%, 92.9%, and 87.9%, respectively; P<0.001 for all). ESBL was more frequently produced in ST131 (53.3%) than in non-ST131 (8.1%) isolates (P<0.01). Conclusion: ST131 E. coli isolates were prevalent uropathogens in children at a single medical center in Korea between 2011 and 2014. Although ST131 isolates showed higher rates of antimicrobial resistance, clinical presentation and outcomes of patients were similar to those of patients infected with non-ST131 isolates.

• Dementia and Neurocognitive Disorders
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• v.22 no.2
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• pp.81-83
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• 2023