• 제목/요약/키워드: spontaneous

검색결과 3,203건 처리시간 0.025초

인삼(人蔘) Butanol 분획(分劃)이 중추작용(中樞作用) 약물(藥物)에 의한 Mouse의 자발(自發) 운동(運動)의 변화(變化)에 미치는 영향에 대한 연구(硏究) (The Effects of the Ginseng Butanol Fraction which Influences Spontaneous Activity by CNS Drugs in Mice)

  • 고건일;김재백
    • Journal of Pharmaceutical Investigation
    • /
    • 제9권4호
    • /
    • pp.13-22
    • /
    • 1979
  • Panax Ginseng C. A. Meyer which has been known for more than 2000 years, occupies a particular place in folk medicine as so called tonic remedy. The brief pharmacological action of Ginseng complied from the numerous reports can be summarized as adaptogenic effect to be increased nonspecific resistance. Among the various components of Ginseng, the effective components has been known Ginseng butanol fraction as so called Ginseng saponin. In order to study on the effect of the Ginseng butanol fraction which influences spontaneous activity by CNS drugs in mice. Experiment of response was measured the change of spontaneous activity by CNS drugs in which mice were treated Ginseng butanol fraction. A method of measuring spontaneous activity in mice used by counting the number of times which were interrupted a beam of light. Results of experiment can be summarized as follows: 1. In case of administrating Ginseng butanol fraction for 1 day, stimulating effect of Ginseng was observed in spontaneous activity by caffeine in comparison with the control. at the first, but after 45 minutes no significant change was observed. 2. In case of administrating Ginseng butanol, fraction for 5days, decreasing tendency was observed in spontaneous activity by caffeine. 3. In case of administrating Ginseng butanol fraction for 10days, marked decrease was observed in spontaneous activity by caffeine in comparison with the control. From the experiment on the increased dose of caffeine, nonsignificant change was observed in comparison with caffeine and sodium benzoate 25mg/kg group. 4. A state of increased resistance was lasted until 5 days, and after 10 days it was disappeared. 5. Otherwise, nonsignificant change was observed for chlorpromazin HCl in comparison with the control. 6. From this result, 10 days administrating of ginseng butanol fraction appeared to have increased resistance in mice against caffeine.

  • PDF

저탄장 자연발화 현상의 수치해석적 연구 (Numerical Study on the Phenomenon of Spontaneous Ignition of Coal Stockpile)

  • 김철진;박이선;손채훈
    • 대한기계학회논문집B
    • /
    • 제34권7호
    • /
    • pp.721-727
    • /
    • 2010
  • 석탄을 야적해두는 저탄장에서 석탄의 자연발화 현상은 안전 문제와 더불어 심각한 경제적 손해를 야기한다. 저탄장에서의 자연발화는 석탄의 산화반응으로 방출되는 열량이 주위로 손실되는 열량보다 클 때 발생한다. 본 연구에서는 2차원 비정상 상태 수치해석을 통해 자연발화 현상을 모사하였고, 수치해석 결과의 타당성을 실험 결과와 비교하여 검증하였다. 수치해석을 통해 구한 시간에 따른 저탄 내부 온도의 변화 곡선은 실험을 통해 측정한 데이터와 잘 일치하였다. 자연발화 인자인 공극률에 따라 저탄장 내부온도 변화 및 압력, 산소 질량 분율의 변화 양상을 분석하였다. 계산 결과를 토대로, 저탄형태의 변화에 따라 저탄장 내부에서의 시간에 따른 온도 변화를 비교 검토하였다. 열점의 형성과 자연발화 메커니즘을 분석하여 제시하였다.

불임 환자와 반복자연유산 환자에서 황체형성호르몬에 대한 연구 (A Study of Luteinizing Hormone in Patients with Infertility and Recurrent Spontaneous Abortion)

  • 남윤성;조용선;이우식;김남근;김세현;차광렬
    • Clinical and Experimental Reproductive Medicine
    • /
    • 제29권2호
    • /
    • pp.91-96
    • /
    • 2002
  • Objective : To evaluate luteinizing hormone (LH) in patients with infertility and recurrent spontaneous abortion. Material and Method: LH was tested by solid phase immunoradiometric assay based on monoclonal and polyclonal anti-LH antibodies. Results: Of 100 infertile patients, the number of less than 5 mIU/ml, 5$\sim$10 mIU/ml, greater than 10 mIU/ml in LH level was 67 (67%), 22 (22%), 11 (11%), respectively. Of 100 patients with recurrent spontaneous abortion, the number of less than 5 mIU/ml, 5$\sim$10 mIU/ml, greater than 10 mIU/ml in LH level was 79 (79%), 18 (18%), 3 (3%), respectively. There was a significant difference between patients with infertility and recurrent spontaneous abortion only in the group with LH level greater than 10 mIU/ml (p=.0325). Conclusions: High LH in the follicular phase is known to decrease pregnancy rate and increase abortion rate. But in this study the incidence of high LH in patients with recurrent spontaneous abortion was low. On the contrary, there was a significant increase of LH in infertile patients. So recurrent spontaneous abortion does not seem to be related to high LH level.

자연기흉의 치료에 대한 정중 흉골절개술의 의의 (Consideration of Median Sternotomy in Managements of Spontaneous Pneumothorax)

  • 김종만
    • Journal of Chest Surgery
    • /
    • 제23권4호
    • /
    • pp.731-735
    • /
    • 1990
  • Simultaneous and non simultaneous bilateral spontaneous pneumothorax patients[273] were reviewed retrospectively from April 1986 to March 1990 in the Dept. of Thoracic and Cardiovascular Surgery, Kyung Hee University Medical College. The incidence of bilateral spontaneous pneumothorax was 13.6%[37] and sexual distribution was male dominant [Male:33, Female:4]. The patients were classified into three major groups according to therapeutic methods: Group I [7]; who were treated with simultaneous bilateral operation for unilateral recurred spontaneous pneumothorax through median sternotomy. Mean age was 20.7 years[17 \ulcorner28] and follow up duration was 7.7 months [3 weeks \ulcorner2 years]. Group II [23];who were treated with staged lateral thoractomy, unilateral thoracotomy and non simultaneous contralateral closed thoracostomy, or simultaneous or non simultaneous bilateral closed thoracostomy. Mean age was 28.6 years [17 \ulcorner56] and follow up duration was 9.8 months[one week \ulcorner3.5 years]. Group III[10] ;who were treated with simultaneous bilateral operation for simultaneous or non simultaneous bilateral spontaneous pneumothorax through median sternotomy. Mean age was 21.4 years[17 \ulcorner28] and follow up duration was 12.8 months[2 weeks \ulcorner2.7 years]. Among the patients managed through median sternotomy simultaneously [Group I and III], there were visible blebs or bullous changed lesions mainly in the apicoposterior segment bilaterally in 15 patients[88.2%] Postoperative complications were 3 cases in Group II [wound infection:2 cases, temporary left wrist drop: one case] but none in Group I and III. Spontaneous pneumothorax recurred in 2 cases, one in Group II and another in Group III but none in Group I. 12 cases of 94 patients[12.8%o] who were treated with unilateral thoracotomy needed contralateral thoracotomy mean 14.9 months[7.5 \ulcorner 25 months] later. Mean age was 20.9 years [17 \ulcorner28]. In conclusion, simultaneous bilateral operation through median sternotomy should be considered in managements of spontaneous pneumothorax, especially in late teens and early twenties except young women for cosmetic reasons.

  • PDF

CNN 기반 스펙트로그램을 이용한 자유발화 음성감정인식 (Spontaneous Speech Emotion Recognition Based On Spectrogram With Convolutional Neural Network)

  • 손귀영;권순일
    • 정보처리학회 논문지
    • /
    • 제13권6호
    • /
    • pp.284-290
    • /
    • 2024
  • 음성감정인식(Speech Emotion Recognition, SER)은 사용자의 목소리에서 나타나는 떨림, 어조, 크기 등의 음성 패턴 분석을 통하여 감정 상태를 판단하는 기술이다. 하지만, 기존의 음성 감정인식 연구는 구현된 시나리오를 이용하여 제한된 환경 내에서 숙련된 연기자를 대상으로 기록된 음성인 구현발화를 중심의 연구로 그 결과 또한 높은 성능을 얻을 수 있지만, 이에 반해 자유발화 감정인식은 일상생활에서 통제되지 않는 환경에서 이루어지기 때문에 기존 구현발화보다 현저히 낮은 성능을 보여주고 있다. 본 논문에서는 일상적 자유발화 음성을 활용하여 감정인식을 진행하고, 그 성능을 향상하고자 한다. 성능평가를 위하여 AI Hub에서 제공되는 한국인 자유발화 대화 음성데이터를 사용하였으며, 딥러닝 학습을 위하여 1차원의 음성신호를 시간-주파수가 포함된 2차원의 스펙트로그램(Spectrogram)로 이미지 변환을 진행하였다. 생성된 이미지는 CNN기반 전이학습 신경망 모델인 VGG (Visual Geometry Group) 로 학습하였고, 그 결과 7개 감정(기쁨, 사랑스러움, 화남, 두려움, 슬픔, 중립, 놀람)에 대해서 성인 83.5%, 청소년 73.0%의 감정인식 성능을 확인하였다. 본 연구를 통하여, 기존의 구현발화기반 감정인식 성능과 비교하면, 낮은 성능이지만, 자유발화 감정표현에 대한 정량화할 수 있는 음성적 특징을 규정하기 어려움에도 불구하고, 일상생활에서 이루어진 대화를 기반으로 감정인식을 진행한 점에서 의의를 두고자 한다.

자연기흉에 동반된 폐암의 수술치험 1예 (Lung Cancer Presenting as Spontaneous Pneumothorax)

  • 이승훈;안용찬;한정호;김진국
    • Journal of Chest Surgery
    • /
    • 제36권7호
    • /
    • pp.535-538
    • /
    • 2003
  • 자발성기흉이 원발성 폐암에 동반되어 나타나는 경우는 드물며, 특히, 원발성 폐암의 초발 소견으로 나타나는 경우는 더욱 드문 것으로 보고되고 있다. 우리나라에서도 폐암 환자의 증가 추세와 더불어 폐암에 동반된 자발성 기흉에 대한 논문이 드물게 발표되고 있다. 그러나, 이러한 경우의 폐암은 진행된 경우가 많아 페종양을 절제하게 되는 경우는 드물고 고식적 치료 즉 자발성 기흉의 페쇄성흉관삽관술, 항암요법, 방사선요법이 주가 되는 경우가 많다. 삼성서울병원 흉부외과에서는 최근 단순한 자연 기흉의 진단하에 기포절제술과 늑막유착술을 시행한 후 검체의 조직학적 검사상 원발성 폐암으로 진단되어 즉시 근치적 절제술 및 방사선요법을 시행하였으나 6개월 내 국소 재발된 1예를 경험하였기에 환자의 추적관찰 후 상태와 더불어 보고하는 바이다.

한국인 청년의 자발적 순목에 관한 연구 (Study of spontaneous blinking for Korean young people)

  • 김상문
    • 한국안광학회지
    • /
    • 제7권2호
    • /
    • pp.101-105
    • /
    • 2002
  • 정상 한국인 청년 60명(남 30명, 여 30명)의 시각활동 및 환경요인에 따른 순목을 측정하였다. 남 여 각각의 자발적 blink rate는 $19.2{\pm}2.0/min$$18.7{\pm}2.0/min$이었고 남자가 약간 더 많았다. 여성에서 contact lens 착용에 따른 blink rate 및 남 여의 시력에 따른 blink rale의 차이는 없었다. 자발적 순목은 시각활동 및 바람과 같은 환경조건에 따라 변하였으나 빛의 세기에 따라서는 유의성 있는 변화를 나타내지 않았다. 주시의 강도가 강할수록 자발적 순목회수는 평상시보다 낮은 반면 바람의 세기가 강할수록 자발적 순목회수는 평상시보다 높았다.

  • PDF

산업용 우드펠릿의 자연발화 특성과 화재위험성에 관한 연구 (A Study on the Spontaneous Ignition Characteristics and Fire Risk of Commercial Wood Pellets)

  • 최유정;김정훈;최재욱
    • Korean Chemical Engineering Research
    • /
    • 제55권5호
    • /
    • pp.623-628
    • /
    • 2017
  • 화력발전소의 연료로 사용되는 우드펠릿을 시료로 하여 시료 용기의 크기에 따른 최소자연발화온도를 구하였으며, 이 온도로부터 Frank-Kamenetskii의 열발화 이론을 이용하여 겉보기 활성화 에너지를 구함으로써 물질의 위험성을 예측하였다. 용기의 크기가 클수록 발화한계온도는 낮아졌으며, 겉보기 활성화 에너지는 37.83 kcal/mol을 구하였다. 또한 시료의 용기가 커질수록 발화유도시간 및 최고온도에 도달하는 시간이 길어졌다.

자연기흉의 원인 및 치료에 관한 연구 (A Study of Etiology and Treatment of Spontaneous Pneumothorax)

  • 김종원;김진식
    • Journal of Chest Surgery
    • /
    • 제8권2호
    • /
    • pp.125-134
    • /
    • 1975
  • The record of 137 patients with spontaneous pneumothorax seen at Busan National University Hospital during past 3years were reviewed to study the possible pathogenesis and its effective management. and the results obtained as follows; 1] The incidence of the "spontaneous" pneumothorax which developed without underlying pathology was 13-1%. The majority of those cases was considered as the result of rupture of subpleural blebs. 2] The incidence of secondary pneumothorax which developed with underlying pathology was 50.0%, in which 42.3% was combined with pulmonary tuberculosis and 8, 0% was combined with pulmonary infection. The traumatic pneumothorax was developed in 36-5% of total series. 3] In age distribution, there was pronounced difference between spontaneous and secondary pneumothorax. The majority of spontaneous pneumothorax cases was 20-30 decade and tall and tall and thin in body structure. In secondary pneumothorax, however, the incidence was relatively high in age group more than 50 years old. 4] The incidence of pneumothorax combined with pulmonary tuberculosis was particularly high in our country, and the cause of pneumothorax was seemed due to the rupture of subpleural caseous foci in some cases, but the majority was seen due to the rupture of emphysematous blebs which were formed with a pathological process of chronic tuberculosis. 5]Closed [tube] thoracotomy was the main therapeutic approach of choice in the great majority ,of pneumothorax in our series with the relapse rate of 19.6%. However, open thoracotomy and adequate surgical procedures should be undertaken in patients with continuous air leakage over 7 days and recurrent attack of pneumothorax.

  • PDF

옥탄가 변화에 따른 가솔린의 발화특성에 관한 연구 (A Study on the Ignition Characteristics of Gasoline due to Variation in Octane Number)

  • 김형석;김원길;최유정;김정훈;최재욱
    • 한국안전학회지
    • /
    • 제33권2호
    • /
    • pp.45-51
    • /
    • 2018
  • This study was conducted to assess the hazards of gasoline in relevance to the changes in octane numbers, and gasoline's spontaneous ignition temperature and instantaneous ignition temperature were measured. Spontaneous ignition temperature of regular gasoline was $301^{\circ}C$ for sample quantity of $100{\sim}125{\mu}{\ell}$. Spontaneous ignition temperature of middle gasoline was $380^{\circ}C$ for sample quantity of $125{\mu}{\ell}$ and that of premium gasoline was $400^{\circ}C$. As gasoline's octane numbers increased, their spontaneous ignition temperatures increased, and their instantaneous ignition temperature were almost identically $499^{\circ}C$ for sample quantity of $125{\mu}{\ell}$. In addition, activation energies of regular gasoline, middle gasoline, and premium gasoline were 10.48 Kcal/mol, 16.89 Kcal/mol, and 24.55 Kcal/mol respectively.