Clinical and Experimental Reproductive Medicine

The Korean Society for Reproductive Medicine (대한생식의학회)
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A Study of Luteinizing Hormone in Patients with Infertility and Recurrent Spontaneous Abortion

불임 환자와 반복자연유산 환자에서 황체형성호르몬에 대한 연구

  • Nam, Yoon-Sung (Department of Obstetrics and Gynecology, College of Medicine, Pocheon CHA University) ;
  • Cho, Yong-Seon (Department of Obstetrics and Gynecology, College of Medicine, Pocheon CHA University) ;
  • Lee, Woo-Sik (Department of Obstetrics and Gynecology, College of Medicine, Pocheon CHA University) ;
  • Kim, Nam-Keun (Institute for Clinical Research, College of Medicine, Pocheon CHA University) ;
  • Kim, Se-Hyun (Institute for Clinical Research, College of Medicine, Pocheon CHA University) ;
  • Cha, Kwang-Yul (Department of Obstetrics and Gynecology, College of Medicine, Pocheon CHA University)
  • 남윤성 (포천중문 의과대학 산부인과학교실) ;
  • 조용선 (포천중문 의과대학 산부인과학교실) ;
  • 이우식 (포천중문 의과대학 산부인과학교실) ;
  • 김남근 (포천중문 의과대학 임상의학연구소) ;
  • 김세현 (포천중문 의과대학 임상의학연구소) ;
  • 차광렬 (포천중문 의과대학 산부인과학교실)
  • Published : 2002.06.30
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Abstract

Objective : To evaluate luteinizing hormone (LH) in patients with infertility and recurrent spontaneous abortion. Material and Method: LH was tested by solid phase immunoradiometric assay based on monoclonal and polyclonal anti-LH antibodies. Results: Of 100 infertile patients, the number of less than 5 mIU/ml, 5$\sim$10 mIU/ml, greater than 10 mIU/ml in LH level was 67 (67%), 22 (22%), 11 (11%), respectively. Of 100 patients with recurrent spontaneous abortion, the number of less than 5 mIU/ml, 5$\sim$10 mIU/ml, greater than 10 mIU/ml in LH level was 79 (79%), 18 (18%), 3 (3%), respectively. There was a significant difference between patients with infertility and recurrent spontaneous abortion only in the group with LH level greater than 10 mIU/ml (p=.0325). Conclusions: High LH in the follicular phase is known to decrease pregnancy rate and increase abortion rate. But in this study the incidence of high LH in patients with recurrent spontaneous abortion was low. On the contrary, there was a significant increase of LH in infertile patients. So recurrent spontaneous abortion does not seem to be related to high LH level.

Keywords

References

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