• 대한한의학방제학회지
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• 제10권1호
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• pp.1-11
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• 2002

From the 24 kinds of literature on the Consumptive disease, it can be concluded as follows. 1. The consumptive disease is the Imparement of deficiency type due to overstrain. it is a general term for these all symptom such as and Deficiency of primordial Qi and Essence of life and blood. 2. The excessive fire due to Yin-Deficiency and the injury of spleen-stomach is accounted much of the cause of Consumptive disease. 3. The main cause of the Hepatic asthenia are the Anger, Consumption and over-thinking. 4. The symptoms of the Consumptive disease are mainly caused by the functional disorder of Liver taking charge of tendons. storing and regulating blood, Heart being in charge of blood circulation. taking charge of mental activities. Spleen taking charge of muscles, transforting and transforming nutrients. Lung taking charge of skins and hairs, taking charge of respirations, Kidney taking charge of bones, storing essence of life. 5. The main symptoms of Hepatic asthenia are flaccidity of muscles and temeons which causes limited movement caused by muscular atonia and the loss of bightness of eyes. 6. The main treatments of Consumptive disease are the invigorating the Spleen-stomach and the invigorating the Kidney and storing essence of life. 7. The treatments of Hepatic asthenia are the moderating the middle and the nourishing the muscles and tendons.

• 동국한의학연구소논문집
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• 제8권1호
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• pp.145-158
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• 1999

본 실험은 사군자탕합창출지유탕(四君子湯合蒼朮地楡湯)의 만성설사(慢性泄瀉)에 미치는 영향을 조사하기 위해 시행되었다. 실험을 위해 흰쥐에 3주일간 castor oil과 대황(大黃)분말을 병행 투여하여 1주일후부터 지속적인 설사를 보인쥐를 선정, 만성설사의 모델로 삼았다. 이를 대조군과 실험군으로 구분하여 위장관 기능과 영양상태를 비교하였고, 개선여부를 알아보기 위해 아무런 처치를 받지 않은 정상군을 검체 체취에 사용하였다. 실험군과 대조군에서 검액 투여전 모두 위장관 기능과 영양상태가 감소한 상태였으며, 검액을 투여한 후 실험군에서 대조군에 비해 위장관 기능과 영양상태가 개선된 경향을 보였는데, 특히 gastrin과 total lipid, 그리고 hematocrit 수치가 유의성 있게 나타나 사군자탕합창출지유탕(四君子湯合蒼朮地楡湯)이 만성설사(慢性泄瀉)에 효과가 있는 것으로 사료된다.

• 대한한의학방제학회지
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• 제32권1호
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• pp.1-9
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• 2024

Objective : This study aims to assess the potential of utilizing large language models in pattern identification education by developing a simulated patient with fatigue and dual deficiency of the heart-spleen pattern. Methods : A simulated patient dataset was constructed using the clinical practice examination module provided by the National Institute for Korean Medicine Development. The dataset was divided into patient characteristics, sample questions, and responses, and utilized to design the system, assistant, and user prompts, respectively. A web-based interface was developed using the Django framework and WebSocket. Results : We developed a simulated fatigue patient representing dual deficiency of the heart-spleen pattern through prompt engineering. To make practical tools, we further implemented web-based interfaces for the examinee's and evaluator's roles. The interface for examinees allows one to examine the simulated patient and provides access to a personalized number for future access. In addition, the interface for evaluators included a page that provided an overview of each examinees' chat history and evaluation criteria in real-time. Conclusion : This study is the first development of an educational tool integrated with a large language model for pattern identification education, which is expected to be widely applied to Korean medicine education.

• 동의신경정신과학회지
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• 제18권3호
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• pp.1-14
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• 2007

The objective of tills study is to identify the difference of somatic characteristics between Hwa-Byung and Major Depression by comparing the pattern identification of Hwa-Byung group and Hwa-Byung with Major Depression group(double diagnosis) Method: According to Hwa-Byung Diagnostic Interview Schedule(HBDIS) and SCID, 17 patients as diagnosed Hwa-Byung and 20 patients as diagnosed Hwa-Byung with Major Depression group(double diagnosis) were recruited. and by depression scale like Hamilton Rating Scale for Depression(HRDS) & Montgomery-Asberg Depression Rating Scale(MADRS), we excluded patients complaining moderate & severe depression among Hwa-Byung group and excluded patients showing mild depression among Hwa-Byung with Major Depression group. After this evaluation, we analysed and compared the pattern identification of both groups by OMS-prime. Result: 1. There were no significant differences of demographic data between both groups. 2. In the result of 'analysis on pattern identification' for all participant used by OMS-prime, most frequent pattern was deficiency of Yin and Yang of the heart(49%). 3. In the result of 'analysis on most correlated pattern identification' used by OMS-prime, for Hwa-Byung group was deficiency of Yin and Yang of the heart(45%) and the next were disharmony of the liver and spleen (20%), generation of phlegm due to stagnation of Gallbladder(15%) deficiency of Qi and Yin of the heart(l0%), And for Hwa-Byung with Major Depression group(double diagnosis) was deficiency of Yin and Yang of the heart(53%), the next were generation of phlegm due to stagnation of Gallbladder(18%), and deficiency of Qi and blood of the heart(l2%), 4. In the result of 'analysis on significant pattern identification' used by OMS-prime, for Hwa-Byung group was deficiency of Yin and Yang of the heart(20%) and the next were disharmony of the liver and spleen(15%), generation of phiegm due to stagnation of Gallbladder(15%), deficiency of Qi and Yin of the heart(14%), And for Hwa-Byung plus Major Depression group(double diagnosis) was deficiency of Yin and Yang of the heart(18%), the next were deficiency of Qi and Yin of the heart(18%), deficiency of Qi and blood of the heart(l0%), generation of phiegm due to stagnation of Gallbladder(18%), Conclusion: Hwabyung is syndrome that have many different symptoms, but there is no difference between Hwa-Byung group and Hwa-Byung with Major Depression group(double diagnosis) on the side of symptoms. Therefore, Hwabyung could be a new model for research on depression in Korean.

• 사상체질의학회지
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• 제27권1호
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• pp.125-137
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• 2015

Objectives The aim of this study was to investigate clinical factors of SQD syndrome by tracking plasma gut hormone (active ghrelin, active Glucagon-like peptide-1(GLP-1), pancreatic polypeptide(PP), total peptide YY(PYY)) profiling of pre-post prandial standard meal between SQD group and normal group. Methods A total of 24 adult participants were consecutively recruited on April 2014. They were diagnosed as either by SQD syndrome or normal by Spleen Qi Deficiency Questionnaire (SQDQ). On the experimental day, blood samplings of 2 ml were repeatedly collected at 6 points from 2 groups for measuring plasma levels of gut hormones. At every point, subjective appetite sensations were self-registered. Results & Conclusions 1. There were significantly lower subjective 'Appetite' (p=0.012) and higher 'Satiety' (p=0.012) in SQD group. At each time point, subjective 'Appetite' was significantly lower at 60 min after breakfast (p=0.034) and 'Satiety' were significantly higher at 15 min (p=0.020) and 120 min (p=0.044) after breakfast in SQD group. 2. There were no significant differences in plasma levels of gut hormones (active ghrelin, active GLP-1, PP, total PYY) between SQD and normal group. Also at each time point, there were no significant differences of plasma levels of gut hormones between SQD and normal group. 3. Changes in plasma levels of gut hormones compared to baseline were not significantly different at each time point between SQD and normal group. Plasma PYY levels compared to baseline increased in SQD group following 15 min and 30 min after breakfast but decreased in normal group. 4. Further investigation is needed to construct gut hormone profiling and in this perspective, we can approach evaluation tool on variable appetite in Traditional Korean Medicine (TKM) syndrome in the future.

• 한방비만학회지
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• 제1권1호
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• pp.43-45
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• 2001

비위의 허한증에 사용하는 이중탕(理中湯)을 비위허한증 환자에 사용하여 체중조절에 도움이 되었기에 문헌고찰과 함께 보고하는 바이다.

• 대한한방내과학회지
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• 제13권1호
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• pp.135-142
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• 1992

Pi(Spleen, 脾) corresponds to central earth and is called as the basis of acquired essence as it has the function of transforting and transforming the nutrients, keeping the blood circulating, and nourishing the muscle and limbs. Recently many studies to research the nature and deficiency of Pi are actively carried out. Especially functional deficiency of Pi(脾虛證) which occupies 60 to 70% or 88% in miscell aneous disease is divided into deficiency of Qi(脾氣虛), Yang(脾陽許), and Yin(脾陰虛), and tought to be positive when three or more such symptoms as anorexia, abdominal distension, loose bowels, pale face and weakness are present. Investigating the resent studies on the nature of the deficiency of Pi shows that Pi has the function of digestive system and also should be considered as functional unit of mult system related immune, metabolic, hematic, muscular, rnddocrine and nervus system. Various experiments as ptyaline activity test and xylose absorption test are used as an indication to deficiency of Pi and would be helpful to understand its nature. As deficiency of Pi appears in many disease and has various manifestations, further studies to diagnose the symptom of Pi using various experiments and oriental medical diagnostic method should be ensued.

• 혜화의학회지
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• 제18권1호
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• pp.67-81
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• 2009

1. According to causes of attack and symptoms, tinnitus is divided into two categories; deficiency and excess. Causes of excess syndrome of tinnitus were wind fire in the liver and gallbladder, phlegm fire, blood stagnation, and heat in meridian system and the causes of deficiency syndrome of tinnitus were qi deficiency or blood deficiency after an illness or delivery, yin deficiency of liver and kidney, and deficiency of sea of the marrow. 2. Tinnitus was related to the vicera and bowels, especially to liver, gallbladder and urinary bladder. 3. In regard of method of treatment, tonify kidney, nourish heart, clear the liver and discharge heat are used according to visera and bowel theory. Clear phlegm and downbear fire are used for phlegm fire. Tonify spleen and kidney is used for ancestral vessel deficiency. Dispel wind and dissipate fire can be used according to theory of five elements' motion and six kinds of natural factors. 4. The basal meridian of acupuncture and moxibustion treatment were the channels of Shaoyang.. 5. Regarding neuropsychiatric aspect of tinnitus, sudden anger and depression of mind were the main mechanism of disease and liver fire was the main cause. The prescriptions for neuropsychiatric tinnitus were Dangguiyonghuehwan, and Yongdamsagantang.

• 한방안이비인후피부과학회지
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• 제27권4호
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• pp.110-120
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• 2014

Objectives : We performed a clinical study to investigate autonomic conditions in persistent allergic rhinitis depending on various pattern identifications and the availability of heart rate variability (HRV) as a pattern identification diagnostic tool. Methods : 32 patients with persistent allergic rhinitis were asked to interview with doctor of Korean Medicine and perform the four pattern questionnaires (Cold-Heat Pattern, Phlegm Pattern, Yin Deficiency pattern, bloodstasis pattern). Then, they were examined their autonomic conditions with heart rate variability test. Results : Patients were classified as three pattern groups (Lung-stomach heat, Lung qi deficiency cold, Lung-spleen qi deficiency) by doctor. In the Lung qi deficiency cold group, Total power of the HRV (TP) and the power of the low frequency component (LF) significantly higher than in the Lung-stomach heat or Lung-spleen qi deficiency group (P < 0.05). Also, Patients were classified as 8 pattern groups (Cold/Heat, Phlegm/Non-phlegm, Yin deficiency/Non-yin deficiency, Bloodstasis/Non-bloodstasis) by four pattern questionnaires. Only in the Yin deficiency group, the power of the low frequency component (LF) significantly lower than in the Non-yin deficiency group (P < 0.05). There were not any significant differences in the rest groups. Conclusions : The result may provide that HRV doesn't reflect well the differences in the various pattern groups, and the HRV's availability is low. Continuous studies are needed to develop the objective and standardized pattern identification diagnostic tool for allergic rhinitis.

• 동의생리병리학회지
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• 제19권5호
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• pp.1146-1153
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• 2005

This study was investigated so that reliability of disease mechanism diagnosis would be examined, the estimation about disease mechanism item of Questionnaires and the relations of disease mechanism would be inquired about 'health diagnosis program' Questionnaires which were used for the object diagnosis of Oriental medicine in the department of Oriental OB&GY, Oriental Medical hospital of Dong-Eui University. We analyzed the results of Questionnaires for 3354 outpatients who had OB & GY disease in the Oriental Medical hospital of Dong-Eui University from April 2000 to March 2004. The diagnosis Questionnaires(after DSOM (r) S.1.1) was the figures 188, the health diagnosis Questionnaires (after DSOM (r) S.1.1) was the figures 137. phiegm deficiency of qi was used in DSOM (r) R.1.1 as it is. The reliability of DSOM (r) S.1.1 was usually higher than DSOM (r) R.1.1 in deficiency of qi blood stasis insufficiency of Yang heat syndrom damp, 5 case disease mechanism. The reliability of DSOM (r) S.1.1 was usually lower than DSOM (r) R.1.1 in blood deficiency stagnation of qi coldness damp dryness liver heart spleen kidney, 8 case disease mechanism. but the great difference wasn't seen, therefore both DSOM (r) S.1.1 and DSOM (r) R.1.1 had similar result. A meeting point both DSOM (r) S.1.1 and DSOM (r) R.1.1 was above 90% in liver spleen blood stasis blood deficiency, 4 case disease mechanism with the exception of phlegm deficiency of Yim nothing of fluctuations of question. A meeting point of coldness that was 82.47% was lowest, A meeting point of the rest disease mechanism was above 85%. The effect that contributed in producing disease mechanism result and in which pure question was over relevance calculation 0.9, insufficiency of Yang damp phlegm that contributed in producing disease mechanism result was lower comparatively in DSOM (r) R.1.1. But the effect that contributed in producing disease mechanism result and in which pure question was over relevance calculation 0.9 except spleen kidney phlegm in DSOM (r) S.1.1