• Proceedings of the KSME Conference
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• 2000.04b
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• pp.715-720
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• 2000

Stratified flow past a three-dimensional obstacle such as a sphere has been a long-lasting subject of geophysical, environmental and engineering fluid dynamics. In order to investigate the effect of the stratification on the near wake, in particular, the unsteady vortex formation behind a sphere, numerical simulations of stratified flows past a sphere are conducted. The time-dependent Navier-Stokes equations are solved using a three-dimensional finite element method and a modified explicit time integration scheme. Laminar flow regime is considered and linear stratification of density is assumed under Boussinesq approximation. The computed results include the characteristics of the near wake and the unsteady vortex shedding. With a strong stratification, the separation on the sphere is suppressed and the wake structure behind the sphere becomes planar, resembling that behind a vertical cylinder.

• Journal of the Korean Institute of Landscape Architecture
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• v.19 no.4
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• pp.58-79
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• 1992

This is a study of Sadaebu(previllaged class in a Yi-Dynasty士 大夫) clan villages in the Andong Area with emphasis on Formantion Process of development. The purposes and the contents of this study are as following : 1. To review the process and the background fo growth of Myung-Mun-Se-Ga(名文大家:the traditional famed & mighty clans) in Yi-Dynasty, in cases of Andong(安東) province. 2. To analyze about formation process of a sphere of their homogeneous clan villages, and to understand the factors affecting their sphere. 3. To identity the background factor of formation of their sphere of traditional clan villages in Andong province.

• Journal of the Korean Institute of Electrical and Electronic Material Engineers
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• v.37 no.2
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• pp.188-194
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• 2024

This paper introduces an optimized oxygen (O₂) plasma surface treatment technique to enhance sphere lithography on hydrophobic photoresist surfaces. The focus is on semiconductor manufacturing, particularly the creation of finer structures beyond the capabilities of traditional photolithography. The key breakthrough is a method that makes substrate surfaces hydrophilic without altering photoresist patterns. This is achieved by meticulously controlling the O₂ plasma treatment duration. The result is the consistent formation of nano and microscale patterns across large areas. From an academic perspective, the study deepens our understanding of surface treatments in pattern formation. Industrially, it heralds significant progress in semiconductor and precision manufacturing sectors, promising enhanced capabilities and efficiency.

• Nuclear Engineering and Technology
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• v.31 no.2
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• pp.182-191
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• 1999

The sorption of UO$_{2}$$^{2+}$ onto goethite and kaolinite under various experimental conditions was successfully interpreted using surface complexation modeling (SCM). The SCM approach used in this work is the triple-layer model (TLM) in which weakly bonded ions are modeled as outer-sphere (ion-pair) complexes and strongly bonded ions as inner-sphere (surface coordination) complexes. The change of ionic strength did not affect the U(VI) sorption onto goethite, thus the formation of inner-sphere surface complexes, (FeO)$_2$UO$_2$ and (FeO)$_2$(UO$_2$)$_3$OH$_{5}$ was assumed to simulate the effects of ionic strength and goethite concentration. On the other hand, the U(VI) sorption onto kaolinite showed ionic strength dependence, thus the formation of AlO-UO$_{2}$$^{2+}$(outer-sphere complex) and SiO(UO$_2$)$_3$OH$_{5}$ (inner-sphere complex) was assumed to simulate the experimental data. In the presence of carbonates, the sorption of U(VI) onto kaolinite decreased in the weakly alkaline pH range. This was well simulated assuming the formation of a outer-sphere surface complex, A1OH$^{2+}$- (UO$_2$)$_2$CO$_3$OH$_3$. Since SCM approach uses thermodynamic data such as surface complexation constants, it is more predictive than empirical modeling approach in which conditional values such as partition coefficient are used. used.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.28 no.5
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• pp.553-559
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• 2004

Stratified flow past a three-dimensional obstacle such as a sphere has been a long-lasting subject of geophysical, environmental and engineering fluid dynamics. In order to investigate the effect of the stratification on the near wake, in particular, the unsteady vortex formation behind a sphere, numerical simulations of stratified flows past a sphere are conducted. The time-dependent Navier-Stokes equations are solved using a three-dimensional finite element method and a modified explicit time integration scheme. Laminar flow regime is considered, and linear stratification of density is assumed under Bossiness approximation. The computed results include the characteristics of the near wake and the unsteady vortex shedding. With a strong stratification, the separation on the sphere is suppressed and the wake structure behind the sphere becomes planar, resembling that behind a vertical cylinder.

• Journal of Powder Materials
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• v.12 no.4 s.51
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• pp.291-295
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• 2005

CdSe hollow sphere with average size of about 30-50 nm was synthesized from the mixed solution of cadmium chloride $(CdCl_2)$, sodium selenosulfate $(Na_2SeSO_3)$ and ethylenediamine(EDA, $H_2NCH_2CH_2NH_2$) at room temperature. The molar ratio of EDA to $Cd^{2+}$ showed the most significant effect on the morphology of CdSe hollow sphere. This paper will present and discuss the possible formation mechanism of CdSe hollow sphere based on the observation of morphological changes.

• Korean journal of communication and information
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• v.27
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• pp.153-181
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• 2004

This study tries 'interdisciplinary research' regarding the formation process of public sphere and the modern media on the Korean society. From the process where the civil society of modern ages is formed, the public sphere was condition that pulls down the feudal system of medieval Europe and appears the civil society. The modern newspaper collected the public opinion from lower part and did play a leading role which forms public sphere in Europe. Even from Korea the literary public sphere and political public sphere were developing inside the Chosun Dynasty period from lower part since 18th century. However the opening of a port became accomplished before making the printing media which is newspaper. As a result the public sphere in Korea was accomplished a conflict-structure. This study cleared where the crisis of Korean journalism is originated by presenting a conflict-structure differently with a transplantation theory or a graft hybrid hypothesis.

• Proceedings of the SCSK Conference
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• 2003.09b
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• pp.313-318
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• 2003

Vitamin C's function and mechanism are comparatively well known among the several kinds of vitamins. Inhibition of free radical. promotion of collagen synthesis, restraint of melanin formation and resolution of melanin are its main functions. But Vitamin C is very easy to oxidize by heat, moisture or air so it causes stability problem to make formulation. To solve these problems unique formulating method or derivatives using method could be effective. Object: First, stabilize 10% of Ascorbic acid as polyol/silicone emulsion and try to make polyol/silicone/polyol anhydrous multiple emulsion secondly. And then, encapsulate with porous power to enhance the stability of Ascorbic Acid from formulating method.

• Molecules and Cells
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• v.42 no.2
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• pp.175-182
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• 2019

microRNAs regulate a diverse spectrum of cancer biology, including tumorigenesis, metastasis, stemness, and drug resistance. To investigate miRNA-mediated regulation of drug resistance, we characterized the resistant cell lines to 5-fluorouracil by inducing stable expression of miRNAs using lenti-miRNA library. Here, we demonstrate miR-551a as a novel factor regulating cell survival after 5-FU treatment. miR-551a-expressing cells (Hep3B-lenti-miR-551a) were resistant to 5-FU-induced cell death, and after 5-FU treatment, and showed significant increases in cell viability, cell survival, and sphere formation. It was further shown that myocyte-specific factor 2C is the direct target of miR-551a. Our results suggest that miR-551a plays a novel function in regulating 5-FU-induced cell death, and targeting miR-551a might be helpful to sensitize cells to anti-cancer drugs.

• Korean Journal of Veterinary Research
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• v.58 no.4
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• pp.201-209
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• 2018

Canine mammary tumors are among the most frequently observed cutaneous tumors in female dogs. Cancer stem cells (CSCs), referred to as tumor-initiating cells, are thought to have properties similar to normal stem cells such as the ability to self-renewal and to differentiate into various cell types. Biological understanding of CSCs and the critical pathways involved in their maintenance are important in research and therapy for mammary tumors. We conducted the present study on sphere formation from REM134 cells by using methylcellulose to produce tumorspheres on a large scale and compared the specific markers of the spheres-formed and plating-cultured REM134 cells. The results revealed that the tumorspheres cultured in methylcellulose had higher seeding density and improved morphology compared to those produced in normal sphere formation medium. Expression levels of stemness markers and CSC-related markers were higher in tumorsphere-forming cells than in plating-cultured cells. Subsequently, we transplanted the tumorsphere-forming and plating-cultured cells into female nude mice to examine their tumorigenic potential. Tumor volume increased rapidly in mice transplanted with tumorsphere-derived cells compared to plating-cultured cells. We observed a novel sphere-forming condition for REM134 cells and showed that REM134 cell tumorspheres can exhibit improved CSC properties.