• Biotechnology and Bioprocess Engineering:BBE
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• 제5권6호
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• pp.422-430
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• 2000

Mechanism of lignin biodegradation caused by basidiomycetes and the history of lignin biodegradation studies were briefly reviewed. The important roles of fungal extracellular ligninolytic enzymes such as lignin and manganese peroxidases (LiP and MnP) were also summarized. These enzymes were unique in their catalytic mechanisms and substrate specificities. Either LiP or MnP system is capable of oxidizing a variety of aromatic substrates via a one-electron oxidation. Extracellular fungal system for aromatic degradation is non-specific, which recently attracts many people working a bioremediation field. On the other hand, an intracellular degradation system for aromatic compounds is rather specific in the fungal cell. Structurally similar compounds were prepared and metabolized, indicating that an intracellular degradation strategy consisted of the cellular systems for substrate recognition and metabolic response. It was assumed that lignin-degrading fungi might be needed to develop multiple metabolic pathways for a variety of aromatic compounds caused by the action of non-specific ligninolytic enzymes on lignin. Our recent results on chemical stress responsible factors analyzed using mRNA differential display techniques were also mentioned.

• 한국디지털건축인테리어학회논문집
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• 제5권2호
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• pp.1-8
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• 2005

Like other artificial architectures, the residence is also hard to be changed after once it has ever been built because its life is approximately estimated up to 20years. Furthermore, it may give big effect to residents as the life Quality. Because of these specificities, it seems to be important to forecast how demand of residential market will be changed and what kind of residential environment should be built in the future. First of all, we should consider about what is a current situation of residential environment in this country before beginning researching resident preferences. In addition, we will also research current and new residential style in other country, which should be concerned in. Finally, this study is researched by domestic male and female residents in their twenties and four ties on purpose to gain information what type of resident style they want and to suggest new ways of future residential environment.

• Applied Biological Chemistry
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• 제41권8호
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• pp.563-567
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• 1998

Computer aided molecular modeling can help to predict the three dimensional structure of the polypeptide without the sample. The study on soybean Bowman-Birk protease inhibitor (SBI) is valuable, because it has been recently known that SBI possesses anticarcinogenic activities and immune-stimulating properties. SBI has several isoinhibitors, whose isolation and characterization were reported in 1990. Among these, DII inhibits trypsin only. The different inhibitory specificities cannot be explained only by their different primary sequences, but is possible with further assistance by the study on their different three dimensional structures. The study on the three dimensional structure of DII using homology method is reported in this paper.

• Journal of Microbiology
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• 제33권2호
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• pp.165-170
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• 1995

The 356 amino acid long lambda integrase protein of bacteriophage .lambda. constains two autonomous DNA binding domains with distinct sequence specificities. The amino terminal domain of integrase is implicated to bind to the arm-type sequences and the carboxyl domain interacts with the coretype sequencess. As a first step to understand the molecular mechanism of the integrase-DNA interaction at the arm-type site, the int(am)94 gene carrying an amber mutation at the 94th codon of the int was cloned under the control of the P$\_$tac/ promoter and the lacI$\_$q/ gene. The Int(am)94 mutant protein of amino terminal 93 amino acid residues can be produced at high level from a suppressor free strain harboring the plasmid pInt(am)94. The arm-type binding activity of Int(am)94 were measured in vivo and in vitro. A comparison of the arm-type binding properties of the wild-type integrase and the truncated Int(am)94 mutant indicated that the truncated fragment containing 93 amino acid residues carry all the determinants for DNA binding at the arm-type sites.

• 한국비블리아학회지
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• 제22권2호
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• pp.221-234
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• 2011

국내에서 적용되고 있는 학교도서관 기준을 분석하여 기준별 특이성과 차이성을 조사하였다. 현행 적용되는 기준으로 7가지 학교도서관 기준이 조사되었으며, 분석결과, 예산편성, 교육서비스, 자료, 인력 등 4가지 주요 문제점이 진단되었다. 기존 학교도서관 기준을 검토하여 학교 도서관의 변화에 따른 새로운 학교도서관 기준의 개선안을 제안하였다.

• 미생물학회지
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• 제20권1호
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• pp.1-10
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• 1982

From Aspergillus nidulans, six suppressor mutants, MSI-MS6, were isolated, and their characteristics were analysed. These were the suppressor mutants for acriflavin resistant and nicotinamide auxotrophic mutant phenotypes. MS1, MS2, MS5 and MS6, were linked to the chromosome IV, I, II respectively, and MS2 was linked to one of the rest chromosomes, MS3 and MS6 mutants had both suppressors for acriflavin resistant marker and for nicotinamide auxotrophic marker. In order to know the stability and efficiency of the suppressors, their reversion frequencies, that is, frequencies of losing the suppressibility, were analysed. Only MS3 and MS5 were reversed with high frequency. The four mutants didn't lose their suppressibilities, and this meant that the suppressors of these four were very stable and highly effcient. The suppressor specificities of these mutants were tested for other mutant's phenotype marker. One of the six suppressors, MS1, had the suppressor specificity for acriflavin resistant marker of 163 strain.

• 한국경영과학회:학술대회논문집
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• 한국경영과학회 2007년도 추계학술대회 및 정기총회
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• pp.43-57
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• 2007

This paper considers the technological competitiveness of aircraft infra industries that are bases of the aircraft industry development in Korea. We performed focus group interviews to aircraft industry specialists and classified the aircraft infra industries by eight fields: metallurgical assembly, general machinery, precision instruments, materials & parts, communication appliances, computer, semi-conductor/ electronic component, electronics. Through the United States patents analysis for the G7 countries and Korea during 1995-2006, we identified the technological specificities and competences of each country. RTA(Revealed Technology Advantage) index and CII(Current Impact Index) are used to examine the technological specificity and technological competence respectively. Finally, we introduced TCI(Technological Competitiveness Index) which could reflect quantitative level as well as qualitative level of patents for each aircraft infra industry. The results show that Korea has occupied the technological competitiveness in the semi-conductor and electronic component industry out of eight aircraft infra industries, and achieved a competitive edge in communication appliance industry in the mid 2000s.

• 동의신경정신과학회지
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• 제28권4호
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• pp.333-340
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• 2017

Objectives: The purpose of this study was to evaluate the efficacy and safety of Korean medicine treatment for pregnant women with panic disorder. Methods: We treated pregnant women with panic disorder with Acupuncture, Herb extract granules, and Korean medicine psychotherapy. PDSS, BAI, and BDI were evaluated every two months. Results: PDSS was reduced from 24 points to 8 points. BAI was reduced from 35 points to 10 points. BDI was reduced from 22 points to 8 points. Mental and body symptoms were also reduced. Both mother and the baby were healthy after delivery. No specificities or adverse effects were reported during the entire treatment. Conclusions: Korean medicine treatment may be effective and safe to control symptoms of pregnant woman with panic disorder.

• 경영과학
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• 제25권2호
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• pp.111-127
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• 2008

This paper analyzes the technological competitiveness of aircraft-based industries that are the basis for the development of aircraft industry in Korea. By performing expert interviews with industry specialists in the field of aircraft technology, the paper categorizes eight fields that are fundamental to the development of the aircraft industry. By analyzing patents of G7 countries and Korea made in the US from 1995 to 2006 we were able to identify the technological specificities and competencies of each country. RTA (Revealed Technology Advantage) index and CII (Current Impact Index) are used to examine the technological specificity and technological competence respectively. Finally, by introducing the TCI (Technological Competitiveness Index) the paper is able to consider both the quantitative level and the qualitative level of patents for each field in the aircraft industry. By analyzing the TCI, the paper concludes that Korea has high technological prowess centered around IT industries such as semi-conductors/ electronics component, communication appliances and consumer electronics. Also Korea is relatively competitive in the precision instruments industry.

• Asian Pacific Journal of Cancer Prevention
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• 제15권6호
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• pp.2395-2403
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• 2014

As the recurrence and mortality rates of bladder cancer are high, research is needed to find suitable biomarkers for early detection, evaluation of prognosis, and surveillance of drug responses. We performed a computerized search of the Medline/PubMed databases with the key words bladder cancer, biomarker, early detection, prognosis and drug response. Several markers were identified at DNA, RNA and protein levels with different sensitivities and specificities. Only a few of the potential bladder cancer biomarkers have been approved for clinical use. Efforts now should be concentrated on finding a panel of markers with acceptable sensitivity and specificity for early detection of bladder cancer.