• 한국의학물리학회:학술대회논문집
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• 한국의학물리학회 2006년도 제33회 추계학술대회 발표논문집
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• pp.142-142
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• 2006

• Journal of Radiation Protection and Research
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• 제24권4호
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• pp.187-193
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• 1999

국내 석탄화력발전소에서 발생되는 비산석탄회의 방사능 농도 분석을 수행하였고 재활용을 위한 방사능 함량의 유해도를 평가하였다. TBP 용매추출법과 알파스펙트로베타를 사용하여 비산석탄회에 존재하는 우라늄 동위원소($^{238}U,\;^{235}U,\;^{234}U$)의 방사능 농도를 측정하였으며, 감마스펙트로메타를 사용하여 $^{226}Ra,\;^{232}Th,\;^{40}K$ 등의 방사능 농도를 결정하였다. 우라늄 동위원소의 농도측정 결과 $^{238}U,\;^{235}U,\;^{234}U$의 방사능 농도는 평균적으로 각각 116.1, 5.01, 및 121.2 Bq $kg^{-1}$으로 나타났으며, $^{234}U/^{238}U$의 방사능 농도비는 $1.04\;{\pm}\;0.03$ 로서 자연상태의 토양중 방사능 농도 비인 1.14 와 유사하였다. 동일시료에 대한 감마측정 결과 $^{226}Ra,\;^{292}Th$ 및 $^{40}K$의 방사능 농도는 각각 $101.7\;{\sim}\;113.9,\;39.5\;{\sim}\;54.2$, 및 $315.0\;{\sim}\;990.6$ Bq $kg^{-1}$ 으로 나타났다. $^{226}Ra,\;^{292}Th$ 및 $^{40}K$ 동위원소의 농도를 사용하여 재활용 목적으로서의 비산석탄회의 방사능 함량 유해도를 평가하였고, 그 결과 본 연구의 대상물질인 비산석탄회의 방사능 함량은 허용기준치 이하로 나타났다.

• 한국의학물리학회:학술대회논문집
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• 한국의학물리학회 2002년도 Proceedings
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• pp.279-281
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• 2002

The results of the specific radioactivity study for Rn-222 in mineral spring water of Khalzan mountain and Janchivlan of Mongolia, using the HP-Ge gamma-spectrometer, are discussed. Some physical and chemical properties in some sample of mineral spring water are determined.

• Nuclear Engineering and Technology
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• 제31권1호
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• pp.9-16
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• 1999

A 330 MWt-sized multi-purpose integral-type reactor, SMART is under development in Korea for the use of nuclear energy other than electricity generation. In this study, various radioactive source terms are estimated for SMART. SMART is different from conventional reactor concepts in operation and design. Therefore Specific Calculation method namely recurrence model is used. This model is based on the change rate in the RC radioactivity materials and operational characteristics of SMART Calculation results show tremendously increase of the levels of RC activity because no cleanup of RC and long term operation.

• Nuclear Engineering and Technology
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• 제50권1호
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• pp.68-79
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• 2018

The Ki-Jang research reactor (KJRR), a new research reactor in Korea, is being planned to fulfill multiple purposes. In this study, as an assessment of the environmental radiological impact, we characterized the atmospheric dispersion and deposition of radioactive materials released by an unexpected incident at KJRR using the weather research and forecasting-mesoscale model interface program-California Puff (WRF-MMIF-CALPUFF) model system. Based on the reproduced three-dimensional gridded meteorological data obtained during a 1-year period using WRF, the overall meteorological data predicted by WRF were in agreement with the observed data, while the predicted wind speed data were slightly overestimated at all stations. Based on the CALPUFF simulation of atmospheric dispersion (${\chi}/Q$) and deposition (D/Q) factors, relatively heavier contamination in the vicinity of KJRR was observed, and the prevailing land breeze wind in the study area resulted in relatively higher concentration and deposition in the off-shore area sectors. We also compared the dispersion characteristics between the PAVAN (atmospheric dispersion of radioactive release from nuclear power plants) and CALPUFF models. Finally, the meteorological conditions and possibility of high doses of radiation for relatively higher hourly ${\chi}/Q$ cases were examined at specific discrete receptors.

• 대한화학회지
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• 제13권2호
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• pp.181-186
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• 1969

The concentration of Strontium-90 in liquid whole milk produced in Korea were measured during past four years. The samples of milk were purchased from dairies in Seoul. Strontium-90 was analysed radiochemically and the amount of stable calcium was also determined. Radioactivity of Yttrium-90 was counted in low background beta counter which has the background of 1.38 cpm. The concentrations of Strontium-90 in the milk are 25.1 PCi $^{90}Sr$/g.Ca in 1965, 26.8 PCi $^{90}Sr$/g. Ca in 1966, 13.7 PCi 90Sr/g.Ca in 1967 and 18.2 PCi $^{90}Sr$/g.Ca in 1968 in annual average. The concentrations of Strontium-90 in the milk of 1967 and of 1968 were decreased approximately compared with the values of 60% 1965 and 1966. From the results we can see that Strontium-90 concentrations in the milk vary roughly proportionally with the specific activity of fallout. Considering on the safety problems, the Strontium-90 levels in the milk produced in Korea were far below the maximum permissible level recommended by ICRP.

• BMB Reports
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• 제29권1호
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• pp.73-80
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• 1996

The effect of albumin on phosphatidylcholine (PC) metabolism in Hep-G2, 3T3-H.ras, and 3T3 cells pre-labelled with [Me-$^3H$]choline was studied. The [$^3H$]choline was more efficiently taken up and incorporated into cellular phospholipids in 3T3-H.ras cells than in Hep-G2 and 3T3 cells. In each of the three cell lines, most of the [$^3H$]choline metabolized into the phospholipids was incorporated into PC and only minor was incorporated into lysophosphatidylcholine (LPC). Bovine serum albumin stimulated the release of [$^3H$]LPC and [$^3H$]PC from each of the three cell lines pre-labelled with [$^3H$]choline. [$^3H$]PC was also released in the absence of albumin but [$^3H$]LPC was not. The efficiency of LPC secretion represented as the proportion of medium [$^3H$]LPC to cellular [$^3H$]choline lipid during a chase period is approximately 9 to 14 times greater in 3T3 cells compared with the transformed 3T3-H.ras and Hep-G2 cells. A similar comparison of published data for rat hepatocytes with Hep-G2 shows secretion to be 35~75 times greater from the rat hepatocytes than from Hep-G2. Also, PC secretion from 3T3 cells was 1.6 times more effective than from 3T3-H.ras, whereas rat hepatocytes secrete PC 2.8~3.8 times more effectively than does Hep-G2. The measurement of specific radioactivity of cellular PC in pre-labelled 3T3 cells showed it to be similar to that of the secreted PC. However, the specific radioactivity of secreted LPC was markedly lower than that of the cellular PC, which suggests that LPC is being secreted from a PC pool distinct from that used for PC secretion.

• Applied Biological Chemistry
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• 제19권3호
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• pp.121-129
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• 1976

우유중에 상당량 존재하는 myo-Inositol의 생성을 알아보기 위하여 3% SE-52를 충진시킨 gas-liquid chromatography에 의해 myo-Inositol의 정량을 행하고 이 myo-Inositol의 유래를 feeding 실험과 $(^{14}C)-glucose$와 (3H)-myo-Inositol을 쥐에 주사한 실험으로 알아 븐 결과 다음과 같은 결과를 얻었다. 1. 쥐우유를 G.L.C. 방법으로 분석하여 우유 100gm.당 61-91mg.의 myo-Inositol (free)을 얻었다. 2. Feeding 실험 결과 우유 myo-Inositol의 85%는 diet에서 흡수되었고 나머지는 mammary gland에서 합성된 것으로 나타났다. 3. $(^{14}C)-glucose$에서 $(^{14}C)-myo-Inositol$ 생성은 lactose의 생성과 비슷하게 한시간이내에 최고에 달하였다. 4. $(^3H)-myo-Inositol$을 lactating rat에 주사하여 실험한 결과 우유 myo-Inositol의 대부분은 혈액 myo-Inositol에서 유래되었다. $(^{14}C)-glucose$를 주사한 후 우유중에 나타난 myo-Inositol의 비방사능(比放射能)은 4시간 후에 혈액 glucose의 8%였다.

• 방사성폐기물학회지
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• 제18권3호
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• pp.347-354
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• 2020

Site characterization for decommissioning Kori Unit 1 is ongoing in South Korea after 40 years of successful operation. Kori Unit 1's containment building is assumed to be mostly radioactively contaminated, and therefore radiation exposure management and detailed contamination investigation are required for decommissioning and dismantling it safely. In this study, site-specific Derived Concentration Guideline Levels (DCGLs) were derived using the residual radioactivity risk evaluation tool, RESRAD-BUILD code. A conceptual model of containment building for Kori Unit 1 was set up and limited occupational worker building inspection scenario was applied. Depending on the source location, the maximum contribution source and exposure pathway of each radionuclide were analyzed. The contribution of radionuclides to dose and exposure pathways, by source location, is expected to serve as basic data in the assessment criteria of survey areas and classification of impact areas during further decommissioning and decontamination of sites.

• Archives of Pharmacal Research
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• 제27권6호
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• pp.633-639
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• 2004

The expression of therapeutic transgenes in recombinant adenoviral vectors is a major cause of toxicity in dividing cancer cells as well as non dividing normal cells. To solve the problem of toxicity to normal cells, we have reported on a recombinant adenoviral vector system （AdLP-） in which the expression of the transgene is directed by the tumor-specific L-plastin promoter （LP） （Chung et al., 1999）. The object of this study was to generate a recombinant adenoviral vector system which would generate tumor cell specific expression of cytosine deaminase （CD） gene. We report the construction of a replication-incompetent adenoviral vector in which CD is driven by the L-plastin promoter （AdLPCD）. Infection of 293 cells by AdLPCD generated the functional CD protein as measured by HPLC analysis for the conversion of 5-Fluorocy-tosine （5-FC） to 5-Fluorouracil （5-FU）. HPLC analysis in conjunction with counting radioactivity for ［6-$^3$H］-5FC and ［6-$^3$H］-5FU demonstrated vector dose-dependent conversion of 5-FC to 5-FU in AdLPCD infected ovarian cancer cells. The results from present and previous studies（Peng et al., 2001； Akbulut et al., 2003） suggest that the use of the AdLPCD／5-FC system may be of value in the treatment of cancer including microscopic ovarian cancer in the peritoneal cavity.