• International Journal of Industrial Entomology and Biomaterials
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• v.25 no.1
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• pp.111-114
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• 2012

In previous studies we have shown that a sw17255 gene was expressed in hemocyte-specific tissues of the silkworm, Bombyx mori L. (Lepidoptera: Bombycidae). It was verified that the sw17255 core promoter region contains elements that regulate the expression of this gene in hemocyte tissue; the selected promoter region spans nucleotides -1 to -2,112 upstream of the start codon. Each of the luciferase reporter gene expression vectors under the control of 4 different kinds of promoter candidates, (-2,112/-1), (-1,640/-1), (-1,169/-1) and (-579/-1), and the control reporter plasmid DNA, were introduced into B. mori larval coelom by direct injection using a syringe. The promoter candidate [E] (-579/-1) showed more than 1.67 fold transcriptional activity compared to control promoter activity. Higher productivity of an expressed gene in the transgenic silkworm by this promoter combination could be achieved in the near future. The foreign recombinant protein could be easily harvested from the blood of the transgenic silkworm.

• Nuclear Engineering and Technology
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• v.56 no.9
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• pp.3566-3570
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• 2024

The production of the radioisotope molybdenum-99 in the WWR-K research reactor is achieved through the activation method ⁹⁸Mo(n,γ)⁹⁹Mo, utilizing a target of natural molybdenum trioxide irradiated under standard conditions (thermal neutron spectra and water environment). Under such conditions, the maximum specific activity of molybdenum-99 reaches (2.3 ± 0.3) Ci/g Mo after 7 d of irradiation. However, the escalating demand for molybdenum-99 and the need to reduce its production cost, necessitates urgent and increased productivity. This study aims to optimize the irradiation conditions for molybdenum powder in the WWR-K reactor to increase the specific activity of molybdenum-99. For this purpose, we evaluated various irradiation capsule designs comprised various neutron moderator materials and thicknesses. Through extensive modeling calculations, we obtained an optimal capsule design that increases the specific activity of molybdenum-99 to 3.31 Ci per 1 g of Mo.

• Korean Journal of Agricultural and Forest Meteorology
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• v.17 no.2
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• pp.126-135
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• 2015

This study was conducted to develop a large scale map of species-specific plantation sites based on selected environmental variables such as topography, soil, and climatic factors in Namwon city. Site index equations by tree species were first regressed to 27 environmental variables that could influence the productivity of forest sites using digital forest site maps, digital climate maps, and the 5th National Forest Inventory data. Site index equations by tree species were all evaluated to estimate site productivity using 4-5 environmental variables, and the models' reliability was confirmed based on evaluation statistics. The determination coefficients of site index equations by species ranged from 0.42 to 0.76. With the site index equations, the site conditions appropriate for productive sites by species were considered to assess spatial distribution of productive areas for each species. The final map for optimal plantation in Namwon city was produced based on both site index equations and site conditions appropriate for productive sites by each species using GIS technique. Field survey was conducted to evaluate the suitability of selected species on the map of species-specific plantation sites. Results showed that the plantation map provides relatively reasonable spatial distribution of productive areas for selected species. It was revealed, however, that the sites evaluated as 'not suitable' for any tree species should be revised and complemented with additional information, especially with the site conditions appropriate for productive sites by species of interest. The outcomes of this study are expected to provide information for making customized species-specific plantation maps.

• KSBB Journal
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• v.20 no.3
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• pp.220-227
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• 2005

Doxorubicin is an anthracycline-family polyketide compound with a very potent anti-cancer activity, typically produced by Streptomyces peucetius. To understand the potential target biosynthetic genes critical for the doxorubicin everproduction, a doxorubicin-specific DNA microarray chip was fabricated and applied to reveal the growth-phase-dependent expression profiles of biosynthetic genes from two doxorubicin-overproducing strains along with the wild-type strain. Two doxorubicin-overproducing 5. peucetius strains were generated via over-expression of a dnrl (a doxorubicin-specific positive regulatory gene) and a doxA (a gene involved in the conversion from daunorubicin to doxorubicin) using a streptomycetes high expression vector containing a strong ermE promoter. Each doxorubicin-overproducing strain was quantitatively compared with the wild-type doxorubicin producer based on the growth-phase-dependent doxorubicin productivity as well as doxorubicin biosynthetic gene expression profiles. The doxorubicin-specific DNA microarray chip data revealed the early-and-steady expressions of the doxorubicin-specific regulatory gene (dnrl), the doxorubicin resistance genes (drrA, drrB, drrC), and the doxorubicin deoxysugar biosynthetic gene (dnmL) are critical for the doxorubicin overproduction in S. peucetius. These results provide that the relationship between the growth-phase-dependent doxorubicin productivity and the doxorubicin biosynthetic gene expression profiles should lead us a rational design of molecular genetic strain improvement strategy.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.29 no.2 s.233
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• pp.333-340
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• 2005

Feedrate is one of the factors that have the significant effects on the productivity, qualify and tool life in the cutting mechanism as well as cutting velocity, depth of cut and width of cut. In this study, in order to realize the high-efficient machining, a new feedrate optimization method is proposed based on the concept that the optimum feedrate can be derived from the allowable cutting power since the cutting power can be predicted from the cutting parameters as feedrate, depth of cut, width of cut, chip thickness, engagement angle, rake angle, specific cutting force and so on. Tool paths are extracted from the original NC program via the reverse post-processing process and converted into the infinitesimal tool paths via the interpolation process. And the novel NC program is reconstructed by optimizing the feedrate of infinitesimal tool paths. Especially, the fast feedrate optimization is realized by using the Boolean operation based on the Goldfeather CSG rendering algorithm, and the simulation results reveal the availability of the proposed optimization method dramatically reducing the cutting time and/or the optimization time. As a result, the proposed optimization method will go far toward improving the productivity and qualify.

• Korean Journal of Computational Design and Engineering
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• v.21 no.4
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• pp.378-388
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• 2016

As the needs for the mega-sized, high-rise and irregular shape of building increase, domestic application of BIM in construction industry is increasing in recent years. In this circumstance, interests in BIM modeling and modeling detail level have been also increased. BIM that is based on a three-dimensions, requires a specific and precise building expressions. And model expression level required for each phase such as design, construction, and maintenance of the construction project could be different as its needs. Because that it is not clear to define the criteria for the expression level of construction BIM model, It is difficult to decide how detail and what to model is appropriate in the practical application of BIM model. It could be the reason why the productivity in construction project became lower and lower. In this study we consider the way how to improve the productivity of BIM and analyze the appropriate representation level of construction BIM model through the experts' survey. The results of study could suggest the basis for an appropriate expression level of construction BIM model.

• Transactions of Materials Processing
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• v.14 no.4 s.76
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• pp.368-374
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• 2005

In the present study we used a diagrammatic analysis of 6 sigma quality control and Taguchi method for injection molding of monitor back-cover, evaluated the influence on the cycle time with part design, mold design, molding process and standardization activity involving design and molding, adopted analysis of sensitivity and effective factors of the part design and molding process conditions for productivity, identified main design molding factors. The contributing factors for the final cycle time could be enumerated as follows; the thickness of hot spot, main nominal part thickness, coolant inlet temperature, melt temperature and cooling line layout, etc.. As a first step, all the critical factors of design process applied to the current monitor housing were investigated through 6 sigma process. Thereafter, the optimal and better critical factors found in the first step were applied to new product design to prove that our process was correct. The Moldflow was used for injection molding simulation, and Minitab software for the statistical analysis, respectively. Finally, the productivity of new design was increased about 33 percents for our specific case.

• Journal of the Korea Convergence Society
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• v.9 no.8
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• pp.17-24
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• 2018

Design patterns can be classified as software reuse technique that might provide effective solutions to specific problems that occur repeatedly in software development. In particular, object-oriented design patterns are incorporated into various software platforms and frameworks to increase software productivity. This paper aims to support general guidelines relating to design patterns for Android-based game programming. The proper use of the design pattern could be effective in not only for software development productivity, but also for post-development software maintenance. This paper provides fundamental procedures and case studies for applying design patterns to game programming on the Android platform. Typical object-oriented design patterns such as MVP, Singleton, Observer, and State have been applied to the development of Android game programs.

• Journal of the Korean Society of Manufacturing Technology Engineers
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• v.23 no.3
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• pp.284-290
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• 2014

Aluminum alloy is a core material for structural parts of aircraft and automobiles to reduce the weight and maintain high specific strength. This study evaluates the machinability and investigates the optimal cutting conditions considering the surface integrity and productivity for Al7050-T7451 milling. The machining variables considered are the feed per tooth, spindle speed, axial depth of the cut, and radial depth of the cut. The machinability evaluation of Al7050-T7451 is conducted by analyzing the cutting force signals, acceleration signals, AE signals, and machined surface conditions. The optimal cutting conditions are determined by analyzing the experimental results using response surface methodology for stable machining considering the productivity and surface integrity.

• Journal of Korea Multimedia Society
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• v.23 no.5
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• pp.700-709
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• 2020

With the development of virtual reality (VR)-related technology and the advent of the 5G era, VR-based streaming games or content have been developed and transmitted at high speed. Although VR technology is also being applied in education, health care, manufacturing, and production fields, its main application is for entertainment. VR technology has been developed based on hardware and various contents have been developed accordingly; however, the number of VR content with high entertainment value is insufficient, and there are primarily hands-on contents. In this paper, we propose a method for developing an writing tool that can enhance the productivity in the development and editing of VR content and create VR contents based on a timeline by reflecting the storytelling rather than by a simple empirical type to solve the bias in content style. The proposed VR content writing tool is expected to increase the productivity in VR content development and contribute to the creation of various styles of content. Its implementation can enable developers to create specific stories in a timeline and support several animation effects.