• Title/Summary/Keyword: specific interaction

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Interaction of Supernova Remnants With the Ambient medium

  • DWARKADAS VIKRAM V.
    • Journal of The Korean Astronomical Society
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    • v.34 no.4
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    • pp.243-246
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    • 2001
  • We summarize various aspects of the interaction of supernova remnants (SNRs) with the ambient medium. We discuss the evolution' of SNRs in environments sculpted by the progenitor star, and summarize the factors on which this evolution depends. As a specific example, we consider the evolution of the medium around a 35 M$\bigodot$ star, and the interaction of the shock wave with this medium when the star explodes as a SN. We also discuss the interaction of Type Ia SNe with the ambient medium, especially the formation and growth of hydrodynamic instabilities.

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Young Chilldren's Causal Reasoning on Psychology and Biology : Focusing on the Interaction between Domain-specificty and Domain-generality (심리와 생물 영역에서의 유아의 인과추론 : 영역특정성과 영역일반성의 상호작용)

  • Kim, Ji-Hyun
    • Journal of Families and Better Life
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    • v.26 no.5
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    • pp.333-354
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    • 2008
  • This study aimed to investigate the role of domain-specific causal mechanism information and domain-general conditional probability in young children's causal reasoning on psychology and biology. Participants were 121 3-year-olds and 121 4-year-olds recruited from seven childcare centers in Seoul, Kyonggi Province, and Busan. After participants watched moving pictures on psychological and biological phenomena, they were asked to choose appropriate cause and justify their choices. Results of this study were as follows: First, young children made different inferences according to domain-specific causal mechanisms. Second, the developmental level of causal mechanisms has a gap between psychology and biology, and biological knowledge was proved to be separate from psychological knowledge during the preschool period. Third, young children's causal reasoning was different depending on the interaction effect of domain-specific mechanisms and domain-general conditional probability: children could make more inferences based on domain-specific causal mechanisms if conditional probability between domain-appropriate cause and effect was evident. To conclude, it can be inferred that the role of domain-specific causal mechanisms and domain-general conditional probability is not competitive but complementary in young children's causal reasoning.

Developing Student-Teacher Interaction Through Task-Based Instruction

  • Alsamadani, Hashem A.
    • International Journal of Computer Science & Network Security
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    • v.22 no.4
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    • pp.47-52
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    • 2022
  • The current study investigates how student-teacher interaction can be developed through task-based teaching in undergraduate students' Saudi teaching and learning context. An experiment was conducted for five weeks on 85 male undergraduate students at a Saudi public university based in Jeddah, Saudi Arabia. The study investigated different types of student-teacher interaction through task-based teaching (speaking activities). The results revealed that the experimental group (43 students) evinced much more enthusiasm, willingness, engagement and readiness in their inclass participation than their peers in the control group (42 students). The student-teacher interaction also helped students to be more responsive to general and specific topics in speaking activities. The study recommends that decision-makers in education make student-teacher interaction part of the student's monthly assessment. It also recommends that more efforts be made to foster the awareness of students, teachers, and parents awareness of the academic and non-academic importance of interaction. One final recommendation of the research is that student-teacher interaction should be more emphasized and integrated into the school curriculum and adopted as a critical teaching strategy.

Characterization of Insulin-like Growth Factor-free Interaction between Insulin-like Growth Factor Binding Protein 3 and Acid Labile Subunit Expressed from Xenopus Oocytes

  • Choi, Kyung-Yi;Kyung, Yoon-Joo;Lee, Chul-Young;Lee, Dong-Hee
    • BMB Reports
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    • v.37 no.2
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    • pp.153-158
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    • 2004
  • The acid-labile subunit (ALS) is known to interact with the IGF binding protein (IGFBP) in the presence of insulin-like growth factors (IGFs). Studies, however, indicate that ALS forms a doublet with IGFBP3, independent of IGFs. To characterize the structural domain required for the IGF-free ALS-IGFBP3 interaction, seven recombinant human IGFBP3 mutants were generated: three deletion mutants and four site-specific mutants that had altering N-terminal regions of IGFBP3. ALS and IGFBP3 mRNAs were co-injected into Xenopus oocytes, and their products were cross-linked and immunoprecipitated using antisera against ALS or IGFBP3. Among the deletion mutants, the mutant of D40 (deleted in 11-40th amino acids) exerted no effect in the interaction with ALS, while D60 (${\Delta}11$-60) demonstrated a moderate reduction. D88 (${\Delta}11$-88), however, showed a significant decrease. In the case of site-specific mutants, the mutation that alterated the IGF binding site (codons 56 or 80) exerted a significant reduction in the interaction, whereas codons 72 or 87 showed no significant change in the interaction with ALS. The stability of the ALS-IGFBP3 interaction was analyzed according to a time-dependent mode. Consistent with the binding study, mutants on the IGF binding sites (56 or 80) consistently show a weakness in the ALS-IGFBP3 interaction when compared to the mutants that covered the non-IGF binding sites (72 or 87). This study suggests that the N-terminal of IGFBP3, especially the IGF binding site, plays an important role in interacting with ALS as well as in stabilizing the dual complex, independent of IGFs.

A Study on the Relationship of Interaction Design - With Emphasis on the Research of Various Knowledge System about the Relationship - (인터랙션 디자인에서의 '관계'에 대한 연구 - 관계에 대한 다 학제적 관점의 고찰을 중심으로 -)

  • 천가원;박영목
    • Archives of design research
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    • v.15 no.3
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    • pp.53-62
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    • 2002
  • If the stage of establishing concept in interaction design approaches only analytic and numeral & quantitative aspects, it would be lack of new and creative ideas of concept for the suitable and proper relationship among the human and tools or machinery which is required in interaction design. This study has explored the possibility of access through the research of diverse point of views in the various knowledge systems about the relationship. That is this study has expanded from improvement-intended approach as analyzing human and tools and solving problems with analytic and engineering aspect to value-intended approach as pursuing new ideas though various points of relationship. Or so, to examine 'Relationship' in other knowledge systems, it could be the basic research for more deepening and specific study in interaction design. To integrate this study, at first, it deals with interaction design and process. Through the specific method, it has investigated the current interaction design and related studies. In the next, it has researched the study of relationship in oriental and western philosophy, cultural science, social science, natural science and engineering so it has examined the relationship in the various points of knowledge systems. Based on the contents, it has considered the possibility of access in interaction design to explain the relationship in the various points of knowledge systems.

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Consideration of Long and Middle Range Interaction on the Calculation of Activities for Binary Polymer Solutions

  • Lee, Seung-Seok;Bae, Young-Chan;Sun, Yang-Kook;Kim, Jae-Jun
    • Macromolecular Research
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    • v.16 no.4
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    • pp.320-328
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    • 2008
  • We established a thermodynamic framework of group contribution method based on modified double lattice (MDL) model. The proposed model included the long-range interaction contribution caused by the Coulomb electrostatic forces, the middle-range interaction contribution from the indirect effects of the charge interactions and the short-range interaction from modified double lattice model. The group contribution method explained the combinatorial energy contribution responsible for the revised Flory-Huggins entropy of mixing, the van der Waals energy contribution from dispersion, the polar force, and the specific energy contribution from hydrogen bonding. We showed the solvent activities of various polymer solution systems in comparison with theoretical predictions based on experimental data. The proposed model gave a very good agreement with the experimental data.

Sex-specific Profiles of Blood Metal Levels Associated with Metal-Iron Interactions

  • Lee, Byung-Kook;Kim, Yangho
    • Safety and Health at Work
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    • v.5 no.3
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    • pp.113-117
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    • 2014
  • The mechanisms by which iron is absorbed are similar to those of divalent metals, particularly manganese, lead, and cadmium. These metals, however, show different toxicokinetics in relation to menarche or menopause, although their interaction with iron is the same. This review focuses on the kinetics of these three toxic metals (manganese, lead, and cadmium) in relation to menarche, pregnancy, and menopause. The iron-manganese interaction is the major factor determining sex-specific differences in blood manganese levels throughout the whole life cycle. The effects of estrogen overshadow the association between iron deficiency and increased blood lead concentrations, explaining why women, despite having lower ferritin concentrations, have lower blood lead concentrations than men. Iron deficiency is associated with elevated cadmium levels in premenopausal women, but not in postmenopausal women or men; these findings indicate that sex-specific differences in cadmium levels at older ages are not due to iron-cadmium interactions, and that further studies are required to identify the source of these differences. In summary, the potential causes of sex-specific differences in the blood levels of manganese, lead, and cadmium differ from each other, although all these three metals are associated with iron deficiency. Therefore, other factors such as estrogen effects, or absorption rate as well as iron deficiency, should be considered when addressing environmental exposure to toxic metals and sex-specific differences in the blood levels of these metals.

Effect of Board Independence on Performance: Interaction Effect with CEO's Firm Specific Experience (이사회의 독립성이 기업성과에 미치는 영향 : CEO의 기업 내 경력과의 상호작용효과에 대한 연구)

  • Yoo, Jae-Wook;Kim, Kwang-Soo
    • Management & Information Systems Review
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    • v.24
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    • pp.1-24
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    • 2008
  • This paper examines the direct effects of board independence and also its interaction effects with CEO's firm specific experience on firm performance. The findings in an hierarchial regression analysis of multiyear sample of computer hardware companies indicate that independent, outsider directors are beneficial to firms' performance when CEO has high-level of firm specific experience whereas it is harmful when CEO has low-level of firm specific experience. However, separating the positions of board chair and chief executive officer that has been used as another means for increasing board independence does not influence to firms' performance. These findings imply that researchers in corporate governance should reconsider the relative weight placed on directors' monitoring and assistance role. Rather than focusing predominantly on directors' willingness or ability to control executives, in future research scholars should yield more productive results by focusing on the assistance directors provide in bringing valued resources to the CEOs and in serving as a source of advice and counsel especially for CEO's improvement of management technique. In addition, they should pay more attention on identifying intervening processes between board and firm performance in order to provide optimal governance mechanisms and configurations to practitioners.

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Tyrphostin ErbB2 Inhibitors AG825 and AG879 Have Non-specific Suppressive Effects on gp130/ STAT3 Signaling

  • Lee, Hyun-Kyoung;Seo, In-Ae;Lee, Sang-Hwa;Seo, Su-Young;Kim, Kyung-Sup;Park, Hwan-Tae
    • The Korean Journal of Physiology and Pharmacology
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    • v.12 no.5
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    • pp.281-286
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    • 2008
  • Although the interaction between gp130 and the ErbB family has frequently been shown in cancer cells, the mechanism of this interaction remains unclear and controversial. In the present study, we found that specific tyrphostin inhibitors of ErbB2 (AG825 and AG879), but not ErbB1 inhibitor (AG1478), suppressed IL-6-induced tyrosine phosphorylation of STAT3 in schwannoma cells. However, biochemical evidence for transactivation of ErbB2 by IL-6 was not observed. Additionally, the inhibition of ErbB2 expression, with either a specific RNAi or transfection of an ErbB2 mutant lacking the intracellular domain did not inhibit the IL-6-induced tyrosine phosphorylation of STAT3. Thus, it seems that tyrphostins, which are known as specific inhibitors of the ErbB2 kinase, may have non-specific suppressive effects on the IL-6/STAT3 pathway.

Seismic analysis of shear wall buildings incorporating site specific ground response

  • Jayalekshmi, B.R.;Chinmayi, H.K.
    • Structural Engineering and Mechanics
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    • v.60 no.3
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    • pp.433-453
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    • 2016
  • During earthquake, the motion of ground is affected significantly by source characteristics, source-to-site path properties and local site conditions. Due to the influence of local soil conditions different places experience distinctive amplitude of surface ground motion. Ground response analysis of a specific site utilizing the borehole information at different locations is done in present study. The ground motion with the highest peak ground acceleration for this site obtained from the ground response analysis is used in finite element soil-structure interaction analysis of multi-storey shear wall buildings with various positions of shear walls. The variation in seismic response of buildings and advantageous position of shear wall are determined. The study reveals that providing shear wall at the core of buildings at the specific site is advantageous among all shear wall configurations considered.