• Asian Pacific Journal of Cancer Prevention
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• v.13 no.5
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• pp.2153-2155
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• 2012

Objective: This study was to assess liver involvement in multiple myeloma with the aid of liver function tests. Materials and Methods: A hospital based retrospective study was undertaken using data retrieved of multiple myeloma from the register maintained in the Department of Biochemistry of the Manipal Teaching Hospital, Pokhara, Nepal between $1^{st}$ January, 2007 and $28^{th}$ February, 2012. We collected biomarkers of liver profiles including bilirubin (Total, Direct and Indirect), total protein, albumin, AG ratio, SGOT, SGPT, ALP, ${\gamma}GT$, LDH, ferritin, renal profile and hematological profile. Descriptive statistics and testing of hypothesis were used for the analysis using EPI INFO and SPSS 16 software. Results: Out of 37 cases of multiple myeloma, serum level of AST, ALT, ALP, ${\gamma}GT$ and LDH were increased above the cut-off point in 22 (59.5%), 24 (64.86%), 13 (35.13%), 9 (24.3%) and 11 (29.7%) respectively. The mean values of AST ($65.5{\pm}28.18$ U/L), ALT ($68.37{\pm}29.74$ U/L), ALP ($328.0{\pm}148.4$ U/L), ${\gamma}GT$ ($44.5{\pm}29.6$ U/L) and LDH ($361.7{\pm}116.5$ U/L), total protein ($9.79{\pm}1.03$ gm/dl) were significantly increased when compared with controls. In contrast, albumin ($3.68{\pm}0.43$ gm/dl) and the AG ratio ($0.62{\pm}0.15$) were significantly decreased. Similarly, anemia, hyperuricemia, azotemia, hypercalcaemia and Bence Jones proteinuria were found in 30 (78.9%), 27 (71.1%), 19 (51.5%), 15 (39.5%) and 16 (42.1%) respectively, in cases of multiple myeloma. Conclusions: While clinical manifestation of liver disease among the multiple myeloma was not common, abnormalities in liver function were characteristic.

• Journal of Broadcast Engineering
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• v.25 no.5
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• pp.758-769
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• 2020

Hybrid broadcasts utilizing heterogeneous networks can provide not only uniform broadcasting services but also various services using broadcast networks and communication networks. In particular, as content is consumed in various countries and regions, demands for personalized services continue to increase, and research on content insertion technology utilizing heterogeneous networks has been actively conducted. The most important technical challenge when inserting content based on heterogeneous networks is that the start of the inserted content, which replaces the original broadcast content at the time of content insertion, should proceed smoothly, and it must be able to accurately return to the original broadcast content. Currently, UHD broadcasting is converted to digital. However, since there is a system that supports the frame rate used in the analog method, when content insertion occurs in a conventional UHD broadcasting service, there is a problem in decoding the broadcast and inserted content. Since the replacement cost of the broadcasting system is astronomical, this paper proposes a content insertion method using by frame control that can support analog methods without replacing transmission equipment.

• Proceedings of the Korean Powder Metallurgy Institute Conference
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• 2002.07a
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• pp.25-37
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• 2002

The most important industrial application of gamma radiation in characterizing green compacts is the determination of the density. Examples are given where this method is applied in manufacturing technical components in powder metallurgy. The requirements imposed by modern quality management systems and operation by the workforce in industrial production are described. The accuracy of measurement achieved with this method is demonstrated and a comparison is given with other test methods to measure the density. The advantages and limitations of gamma ray densitometry are outlined. The gamma ray densitometer measures the attenuation of gamma radiation penetrating the test parts (Fig. 1). As the capability of compacts to absorb this type of radiation depends on their density, the attenuation of gamma radiation can serve as a measure of the density. The volume of the part being tested is defined by the size of the aperture screeniing out the radiation. It is a channel with the cross section of the aperture whose length is the height of the test part. The intensity of the radiation identified by the detector is the quantity used to determine the material density. Gamma ray densitometry can equally be performed on green compacts as well as on sintered components. Neither special preparation of test parts nor skilled personnel is required to perform the measurement; neither liquids nor other harmful substances are involved. When parts are exhibiting local density variations, which is normally the case in powder compaction, sectional densities can be determined in different parts of the sample without cutting it into pieces. The test is non-destructive, i.e. the parts can still be used after the measurement and do not have to be scrapped. The measurement is controlled by a special PC based software. All results are available for further processing by in-house quality documentation and supervision of measurements. Tool setting for multi-level components can be much improved by using this test method. When a densitometer is installed on the press shop floor, it can be operated by the tool setter himself. Then he can return to the press and immediately implement the corrections. Transfer of sample parts to the lab for density testing can be eliminated and results for the correction of tool settings are more readily available. This helps to reduce the time required for tool setting and clearly improves the productivity of powder presses. The range of materials where this method can be successfully applied covers almost the entire periodic system of the elements. It reaches from the light elements such as graphite via light metals (AI, Mg, Li, Ti) and their alloys, ceramics ($AI_20_3$, SiC, Si_3N_4, $Zr0_2$, ...), magnetic materials (hard and soft ferrites, AlNiCo, Nd-Fe-B, ...), metals including iron and alloy steels, Cu, Ni and Co based alloys to refractory and heavy metals (W, Mo, ...) as well as hardmetals. The gamma radiation required for the measurement is generated by radioactive sources which are produced by nuclear technology. These nuclear materials are safely encapsulated in stainless steel capsules so that no radioactive material can escape from the protective shielding container. The gamma ray densitometer is subject to the strict regulations for the use of radioactive materials. The radiation shield is so effective that there is no elevation of the natural radiation level outside the instrument. Personal dosimetry by the operating personnel is not required. Even in case of malfunction, loss of power and incorrect operation, the escape of gamma radiation from the instrument is positively prevented.

• Korean Security Journal
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• no.39
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• pp.241-268
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• 2014

This paper is a study on the industrial security specialists of organizations in possession of industrial technology and their compliance motivations towards security policies. The focus is on organizational justice, organizational attachment and empowerment based on our hypothesis that compliance motivations are shaped, not only by the organization itself but, also by the attitude and principle of the organization's members. The objective is to propose a direction for administrative security policy to increase prevention of industrial technology leakage by identifying the factors' significance through hypothesis testing and thereafter investigating the influencing relationship. Survey questionnaires are collected from the participants of a regular educational program provided by the Korean Association for Industrial Technology Security (KAITS) and analyzed using SPSS 21.0 and AMOS 21.0 software. Through various statistical analyses, following results are acquired. First, procedural fairness and organizational attachment are found to motivate security supervisors to comply with security policies. Particularly, the relationship between procedural fairness and compliance motivations towards security policies is fully mediated by organizational attachment, suggesting that improved fairness at the organizational level will lead to an increase in organizational attachment, which will encourage the individuals to comply with security policies. Additionally, empowerment of the individuals in organizations partially mediates the relationship between procedural fairness and organizational attachment, confirming that procedural fairness empowers each individual and increases his organizational attachment. Specifically, in order to maximize compliance of security policies, businesses should demonstrate procedural fairness when compensating their employees for their work to empower them and increase their organizational attachment, which can increase their will to comply with existing security policies. This research provides insights into how to encourage security supervisors to comply with security policies by increasing their empowerment and organizational attachment.

• Toxicological Research
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• v.34 no.3
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• pp.221-229
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• 2018

Tenofovir nanoparticles are novel therapeutic intervention in human immunodeficiency virus (HIV) infection reaching the virus in their sanctuary sites. However, there has been no systemic toxicity testing of this formulation despite global concerns on the safety of nano drugs. Therefore, this study was designed to investigate the toxicity of Tenofovir nanoparticle (NTDF) on the liver and kidney using an animal model. Fifteen adult male Sprague-Dawley (SD) rats maintained at the animal house of the biomedical resources unit of the University of KwaZulu-Natal were weighed and divided into three groups. Control animals (A) were administered with normal saline (NS). The therapeutic doses of Tenofovir (TDF) and nanoparticles of Tenofovir (NTDF) were administered to group B and C and observed for signs of stress for four weeks after which animals were weighed and sacrificed. Liver and kidney were removed and fixed in formal saline, processed and stained using H/E, PAS and MT stains for light microscopy. Serum was obtained for renal function test (RFT) and liver function test (LFT). Cellular measurements and capturing were done using ImageJ and Leica software 2.0. Data were analysed using graph pad 6, p values < 0.05 were significant. We observed no signs of behavioural toxicity and no mortality during this study, however, in the kidneys, we reported mild morphological perturbations widening of Bowman's space, and vacuolations in glomerulus and tubules of TDF and NTDF animals. Also, there was a significant elevation of glycogen deposition in NTDF and TDF animals when compared with control. In the liver, there were mild histological changes with widening of sinusoidal spaces, vacuolations in hepatocytes and elevation of glycogen deposition in TDF and NTDF administered animals. In addition to this, there were no significant differences in stereological measurements and cell count, LFT, RFT, weight changes and organo-somatic index between treatment groups and control. In conclusion, NTDF and TDF in therapeutic doses can lead to mild hepatic and renal histological damage. Further studies are needed to understand the precise genetic mechanism.

• Journal of KIISE:Software and Applications
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• v.32 no.6
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• pp.554-569
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• 2005

In the semistructured distributed documents, it is very difficult to formalize and implement the query processing system due to the lack of structure and rule of the data. In order to precisely retrieve and process the heterogeneous semistructured documents, it is required to handle multiple mappings such as 1:1, 1:W and W:1 on an element simultaneously and to generate the schema from the distributed documents. In this paper, we have proposed an query processing algorithm for querying and answering on the heterogeneous semistructured data or documents over distributed systems and implemented with a metadata interface. The algorithm for generating local queries from the global query consists of mapping between g1oba1 and local nodes, data transformation according to the mapping types, path substitution, and resolving the heterogeneity among nodes on a global input query with metadata information. The mapping, transformation, and path substitution algorithms between the global schema and the local schemas have been implemented the metadata interface called DBXMI (for Distributed Documents XML Metadata Interface). The nodes with the same node name and different mapping or meanings is resolved by automatically extracting node identification information from the local schema automatically. The system uses Quilt as its XML query language. An experiment testing is reported over 3 different OEM model semistructured restaurant documents. The prototype system is developed under Windows system with Java and JavaCC compiler.

• Fire Science and Engineering
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• v.34 no.4
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• pp.69-77
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• 2020

With the recent enlargement and complication of buildings, damage caused by the incidents of fires breaking out are escalating. Consequently, the use of sprinkler facilities is increasing among water-based fire extinguishing systems. Piping materials used in fire prevention systems include carbon steel (for general or pressure pipeline), CPVC, copper, and stainless-steel. Among these, the steel and CPVC pipes, which are commonly employed in fire prevention, were considered for testing the reliability of the water-based systems. This analysis was performed using the PIPENET software to perform hydraulic calculations in order to examine the flow and pressure at the terminal head when the corrosion coefficient was applied; this coefficient was applied considering the aging of pipes. Assuming a uniform pipe diameter in the steel pipes, the rated flow in the pump installed on the first floor of the basement was reduced by over 10% after 20 years had passed (C value of 90); moreover, the reduction in pressure and flow at its terminal head exceeded 30% and 16.5%, respectively. The results indicate that it is difficult to ensure the reliability of these fire prevention facilities. Furthermore, according to our estimation, considering 30 years had passed (C value of 80), the rated flow of the pump was reduced by over 15%, and the corresponding reduction in pressure and flow at its terminal head exceeded 42% and 24%, respectively.

• Journal of Radiation Protection and Research
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• v.40 no.1
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• pp.46-54
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• 2015

The thermoluminescence (TL) and optically stimulated luminescence (OSL) are commonly used to measure and record the expose of individuals to ionization radiation. Design and performance test results of a newly developed TL and OSL measurement system are presented in this paper. For this purpose, the temperature of the TL material can be controlled precisely in the range of $1{\sim}1.5^{\circ}C$ by using high-frequency (35 kHz) heating system. This high-frequency power supply was made of transformer with ferrite core. For optical stimulation, we have completed an optimal combination of the filters with the arrangement of GG420 filter for filtering the stimulating light source and a UG11 filter at the detecting window (PMT). By using a high luminance blue LED (Luxeon V), sufficient luminous intensity could be obtained for optical stimulation. By using various control boards, the TL/OSL reader device was successfully interfaced with a personal computer. A software based on LabView program (National Instruments, Inc.) was also developed to control the TL/OSL reader system. In this study, a multi-functional TL/OSL dosimeter was developed and the performance testing of the system was carried out to confirm its reliability and reproducibility.

• Phonetics and Speech Sciences
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• v.6 no.2
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• pp.73-79
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• 2014

Alveolar fricative sounds /s/ and /s'/ are learned last for normal children in the speech development process for Koreans. These are especially difficult to articulate for hearing-impaired children often causing articulation errors. The acoustic phonetic evaluation uses testing tools to provide indirect and object information. These objective resources can be compared with standardized resources on speech when interpreting the results of a test. However, most previous studies in Korea did not consider acoustic studies that used the spectrum moment values of hearing-impaired children. Therefore, this study was conducted to compare the characteristics of hearing-impaired children's pronunciation of fricative sounds using spectrum moment values. For this purpose, the study selected a total of 10 hearing-impaired children (5 boys and 5 girls) currently in 3rd or 5th grade and attending one of the elementary schools in Seoul or Gyeonggi-do. For the selection process, their age, type of hearing aid, implantation of hearing aid (CI) before two years of age, hearing capacity (dB) before and after wearing the hearing aid, duration of speech rehabilitation, and time of learning alveolar fricative sounds were all considered. Also, 10 normal children (5 boys and 5 girls) were selected among 3rd or 5th grade students attending one of the elementary schools in Seoul or Gyeonggi-do. The subjects were asked to read the carrier sentence, "I say _______," including a list of 12 meaningless syllables composed of CV and VCV syllables, including alveolar fricative sounds /s/ and /s'/ and vowels /a/, /i/, and /u/. The recorded resources were processed through the Time-frequency Analysis Software Program to measure M1 (mean), M2 (variance), M3 (skewness), and M4 (kurtosis) of the fricative noise. No significant differences were found when comparing spectrum threshold values in the acoustic phonetic characteristics of hearing-impaired children and normal children in alveolar fricative sound pronunciation according to vowels /a/, /i/, and /u/, alveolar fricative sounds /s/ and /s'/, and syllable structure (CV, VCV) other than, for M3 in the comparison of groups according to disability. In the comparison of syllable structures, there were statistically significant differences in M1, M2, M3, and M4 with clinical significance. However, there was no significant difference in results when comparing the alveolar fricative sounds according to the vowels.

• Journal of KIISE:Software and Applications
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• v.29 no.1_2
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• pp.42-52
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• 2002

Information extraction(IE) is a process of recognizing and fetching particular information fragments from a document. In previous work, most IE systems generate the extraction rules called the wrappers manually, and although this manual wrapper generation may achieve more correct extraction, it reveals some problems in flexibility, extensibility, and efficiency. Some other researches that employ automatic ways of generating wrappers are also experiencing difficulties in acquiring and representing useful domain knowledge and in coping with the structural heterogeneity among different information sources, and as a result, the real-world information sources with complex document structures could not be correctly analyzed. In order to resolve these problems, this paper presents an agent-based information extraction system named XTROS that exploits the domain knowledge to learn from documents in a semi-structured information source. This system generates a wrapper for each information source automatically and performs information extraction and information integration by applying this wrapper to the corresponding source. In XTROS, both the domain knowledge and the wrapper are represented as XML-type documents. The wrapper generation algorithm first recognizes the meaning of each logical line of a sample document by using the domain knowledge, and then finds the most frequent pattern from the sequence of semantic representations of the logical lines. Eventually, the location and the structure of this pattern represented by an XML document becomes the wrapper. By testing XTROS on several real-estate information sites, we claim that it creates the correct wrappers for most Web sources and consequently facilitates effective information extraction and integration for heterogeneous and complex information sources.