• 한국보건간호학회지
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• 제22권1호
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• pp.18-26
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• 2008

Purpose: To assess the health status and health behavior characteristics of immigrant women married to Koreans. Method: A descriptive research design was employed. Fifty female marriage immigrants who were clients of the visiting health program at W public health center were recruited. After full consent, direct interview with a structured questionnaire and physical measurements were conducted by visiting health nurses. Descriptive statistics were utilized. Results: All of the subjects showed normal blood sugar. 25.7% of them exhibited extreme body weight condition of either obesity or low body weight by BMI. 36.4% had pre-hypertension stage and 15.9% had first stage of hypertension. Only two of the women had been diagnosed with hypertension and treated by a doctor. Almost all (95%) of them perceived their general health status as good or moderate. Most of them did not exercise, smoke or drink. Regarding dental care, no subject brushed before lunch. and only one did between meals. About 30$\sim$60% of subjects had undergone health screening. Conclusion: Health education is needed for immigrant women married to Koreans to enhance their health behavior, prevent life style disease and improve their health.

• 보건행정학회지
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• 제13권3호
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• pp.1-20
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• 2003

The purpose of this study was to investigate the current status of health promotion policies about antismoking, and the relationship between policy status, enforcement of smoking restrictions and perceptions of smoking behaviour among teachers. A representative sample of 173 teachers$.$school inspectors from 150 elementary$.$middle$.$high schools in Gangwon-do was surveyed during Gangwon-do Office of Education's antismoking and temperance training course in 2002 (response rate 60.7%). One staff member from each school was also analyzed regarding school antismoking polices for students and teachers in several locations within and outside the school building. The results showed that 118 elementary$.$middle$.$high schools (78.7%) had an antismoking policy and more schools had a written policy on student antismoking than on teacher antismoking. Most schools (92.4%) in the sample banned smoking by students, but 52 schools (44.1%) allowed smoking by teachers in restricted areas. However, teachers reported seeing smoking sometimes in the toilets (42.7%) or the playground (40.0%) among students and sometimes in the staff room (31.3%) or about every day on school premises (52.7%) among teachers. Irrespective of the type of policy or restrictions on smoking, the association between having a ban on student/teacher smoking and teachers' perceptions of student/teacher smoking in school was not significant. In conclusion, we suggest that most schools must have explicitly an antismoking policy on both students & teachers and enforce consistently a ban in promoting a healthy school environment(smoke-free schools).

• 한국패션뷰티학회지
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• 제1권1호
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• pp.49-64
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• 2003

A study on skin care of middle-aged women was conducted to develop proper skin care program. The study was performed from January 25, 2003 through March 24, 2003 by using questionnaires. The subjects were 380 from some area in Youngnam province. All subjects were females from 40 to 59 years. The results of this study are summarized as follows. 1. According to general characteristics of the subjects, 36.8% of them was from 40 to 44years old; 61.3% 'high school graduate' ; 61.1% 'housewife';89.2% 'married' ;76.1% 'middle class' ;55.8% 'living in small or medium sized city'. In the case of physical health conditions, 55.8% of the respondents was in good health and 63.9% answered that their face skins were healthy. Those who don't drink were 54.5%, and those who don't smoking were 92.9%. 2. In case of the knowledge level of skin care, it showed significant difference in the variables of education, occupation, and economic status. According to the knowledge level of skin care by physical health conditions, it was highest in the case of physically healthy respondents(7.77 point). Those who do not smoke marked higher knowledge level of skin care than those who smoke. Those who exercise also marked higher knowledge level of skin care, than those who don't exercise. 3. 86.8% of the subjects experienced the massage at home. It showed significant difference in the variable of education and place of residence. The knowledge and habit of skin care of middle-aged women showed significant difference according to the variable of education, economic status, and place of residence. Therefore, related professionals and organizations relating to the skin care must make efforts to develop education program for effective skin care for middle-aged women in order to enhance the knowledge level of skin care and information about skin health.

• 기본간호학회지
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• 제9권2호
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• pp.311-322
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• 2002

Purpose: The purpose of this study was to test the physical and psychological-emotional status according to type of personality of female college student smokers and to provide baseline data for smoking cessation education programs for women. Method: The data were collected from May to June. 2002. The subjects were 119 female students who smoked. The data were analyzed using SPSS/PC. Results : The results are as follows 1. There were 91 (76.5%) A type and 28 (23.5%) B Type personality types, indicating that female student smokers were more frequently type A rather than type B. 2. Perceived health status by personality type indicated that those with type B ($27.71{\pm}4.67$) perceived higher health status than those with type A ($26.53{\pm}4.60$) but the result was not statistically significant (p = 237). 3. Perceived stress by personality type indicated that those with type B ($83.71{\pm}13.13$) perceived more stress than those with type A ($70.52{\pm}12.35$). 4. Differences between depression by personality type indicated that those with type B ($47.21{\pm}8.53$) perceived more stress than those with type A ($45.42{\pm}7.32$) but this was not statistically significant (p = .277). 5. There were significant negative correlations between perceived health status and stress (r=-0.300. p<0.004), depression and perceived health status (r=-.456. p<0.000). There was significant positive correlation between stress and depression (r= .700, p<0.000). 6. There was no significant difference between perceived health status, stress, or depression according to general characteristics. Conclusion: According to the results, researchers should continually identify women's smoking behavior included various physical and psychological variables related to women's health. In addition, programs for improving physical and psychological health should be designed and operated to decrease the perception of stress and to increase the perception of health motivation for women smokers.

• 한국응용과학기술학회지
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• 제29권1호
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• pp.129-140
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• 2012

우리나라에서 건축물 내장재의 화재안전성능은 국토해양부 고시 제2011-39호에 의한 평가방법에 의해 불연성시험(KS F ISO 1182), 열방출률시험(KS F ISO 5660) 및 가스유해성시험(KSF 2271)을 실시하여 그 결과로서 분류하도록 되어 있다. 그 중 연기 및 연소독성가스에 대한 시험인 가스 유해성 시험은, 건축재료 및 내장재의 연소시 발생하는 가스의 유해성을 마우스의 평균 행동정지시간으로 측정하는 방법으로 사용하여 왔다. 이 중 연소 독성가스 4종(HCl, HF, HCN, $SO_2$) 흡입독성시험방법의 확립을 위하여 ICR계 mouse와 전신흡입노출장치를 이용하여, 독성가스 노출 및 병리검사를 수행하였다. 그 결과 호흡기관지와 가까운 폐포에서 대식세포(Macrophage)의 침윤을 유발하는 것으로 나타났고, 4종의 물질에 대한 조직의 병리검사로 전체적으로 충혈과 울혈은 확인되었다. 조직 중 폐와 신장에서 조직손상이 심하였고, 물질로는 HCN이 가장 많은 병리소견을 보였다.

• 대한지역사회영양학회지
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• 제3권3호
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• pp.358-367
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• 1998

The study purpose was to investigate psychosocial factors related to smoking among adolescent boys. The Theory of Planned Behavior provide the basis for the study. Twenty-five attitudinal beliefs, 9 normative beliefs and 20control beliefs were identified through questionnaire development. The data were analyzed using t-test and χ2-test. Thirty-three percent of 300 students were smokers. Most of the beliefs examined were significantly different between smokers(n=92) and nonsmokers(n=92). With respect to attitudinal beliefs, smokers responded less negatively on the items of bad health effects of smoking such as sore throat, headache, chest pain, risk of cancer and bad blood circulation(p<0.001), and decreased physical strength(p<0.05). Smokers believed less negatively on the items that smoking leads to bothering others, bad breath, yellow teeth and making them spend money(p<0.001). In contrast, smokers felt more positively on smoking as a means of stress management, relaxing, helping digestion(P<0.001). Smokers felt less pressure for not smoking from significant others. Especially mother, siblings, friends, girl friends, seniors of school were important sources of influence regarding subject's smoking. Smokers felt less confident in controlling the urge to smoke in several situations including; when they were with friends or asked to smoke by friends; after the meal, or drinking; when they were bored or stressed, upset, and when they felt unstable(p<0.001). Smokers also scored lower on specific skills to quit or control the urge to smoke as well as overall perceived control, compared to nonsmokers(p<0.001). These results suggest that interventions for adolescents incorporate diverse strategies to increase the perceived control over smoking in specific situations as well as overall perceived control, to help them realize and modify attitudinal beliefs, and to elicit support from significant others for not smoking. (Korean J Community Nutrition 3(3) : 358∼367,1998)

• Yonsei Medical Journal
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• 제59권9호
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• pp.1079-1087
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• 2018

Purpose: Obstructive sleep apnea and chronic obstructive pulmonary disease are independent risk factors of cardiovascular disease (CVD), and their coexistence is known as overlap syndrome (OS). Endothelial dysfunction is the initial stage of CVD; however, underlying mechanisms linking OS and CVD are not well understood. The aim of this study was to explore whether OS can lead to more severe inflammation and endothelial apoptosis by promoting endothelial dysfunction, and to assess the intervention effects of antioxidant tempol. Materials and Methods: Male Wistar rats (n=66) were exposed to normal oxygen [normal control (NC) group], intermittent hypoxia (IH group), cigarette smoke (CH group), as well as cigarette smoke and IH (OS group). Tempol intervention was assessed in OS group treated with tempol (OST group) or NaCl (OSN group). After an 8-week challenge, lung tissues, serum, and fresh blood were harvested for analysis of endothelial markers and apoptosis. Results: The levels of intracellular adhesion molecule-1, vascular cellular adhesion molecule-1, and apoptosis in circulating epithelial cells were the highest in OS group and the lowest in NC group. These levels were all greater in IH group than in CH group, and were lower in OST group than in OS and OSN groups (all p<0.001). Conclusion: Synergistic effects of IH with cigarette smoke-induced emphysema produce a greater inflammatory status and endothelial apoptosis. OS-related inflammation and endothelial cell apoptosis may play important roles in promoting cardiovascular dysfunction, and antioxidant tempol could achieve a partial protective effect.

• Child Health Nursing Research
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• 제10권3호
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• pp.272-281
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• 2004

Purpose: To investigate the prevalence of smoking behavior among elementary students which may serve as basic data for developing a smoking prevention program. Method: Questionnaires were given to 734 fourth, fifth, and sixth graders in five elementary schools in U county, North Chungcheong Province. Data were collected from 8 to 20 December, 2003; and analyzed using SPSS/PC for descriptive and chi-square statistics. Result: Of these students, 19.9％ reported that they had smoked and 0.8％ answered they are current smokers. They reported that the first smoking started during third grade (26.0％), at their homes (38.4％), and out of curiosity (74.0％). They reported severe coughing when they first smoked (56.2％). Smoking experiences were significantly related to grade, gender, and academic performance. Similarly, environmental characteristics such as residential area, parental status, father's job, parental attention, home atmosphere, and smoking siblings or friends were significantly related to smoking behavior. Among non-smokers, 86.4％ intended not to smoke and 1.4％ would like to smoke in the future. Conclusion: Certain school and environmental characteristics were associated with smoking experimentation. Therefore teachers and parents should use this information to develop and guide smoking prevention programs.

• BMB Reports
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• 제54권10호
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• pp.522-527
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• 2021

Lysine-specific demethylase 1 (LSD1) is an epigenetic regulator that modulates the chromatin status, contributing to gene activation or repression. The post-translational modification of LSD1 is critical for the regulation of many of its biological processes. Phosphorylation of serine 112 of LSD1 by protein kinase C alpha (PKCα) is crucial for regulating inflammation, but its physiological significance is not fully understood. This study aimed to investigate the role of Lsd1-S112A, a phosphorylation defective mutant, in the cigarette smoke extract/LPS-induced chronic obstructive pulmonary disease (COPD) model using Lsd1^SA/SA mice and to explore the potential mechanism underpinning the development of COPD. We found that Lsd1^SA/SA mice exhibited increased susceptibility to CSE/LPS-induced COPD, including high inflammatory cell influx into the bronchoalveolar lavage fluid and airspace enlargement. Additionally, the high gene expression associated with the inflammatory response and oxidative stress was observed in cells and mice containing Lsd1-S112A. Similar results were obtained from the mouse embryonic fibroblasts exposed to a PKCα inhibitor, Go6976. Thus, the lack of LSD1 phosphorylation exacerbates CSE/LPS-induced COPD by elevating inflammation and oxidative stress.

• Environmental Analysis Health and Toxicology
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• 제26권
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• pp.11.1-11.6
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• 2011

Objects: The prevalence of asthma has increased in recent decades globally. The objective of the present study is to elucidate whether hospitalization for bronchiolitis in infancy and low socioeconomic status interact for bronchial hyperreactivity during teenage years. Method: We studied 522 children age 13-14 years attending schools in rural and urban areas to investigate the risk factors for bronchial hyperreactivity (BHR), defined as a provocation concentration of methacholine that causes a decrease of 20% ($PC_{20}$) in forced expiratory volume within 1 second. Clinical examination, skin prick test, spirometry, and methacholine challenge were performed on all study subjects, who provided written consent. We used multivariate logistic regression to investigate the risk factors for BHR, and analyze the interaction between hospitalization for bronchiolitis in infancy and low socioeconomic status. Results: Forty-six (10.3%) positive BHR cases were identified. In the multivariate logistic analysis, as independent predictors of BHR, adjusted odds ratio of bronchiolitis diagnosed before 2 years of age in low income families was 13.7 (95% confidence interval, 1.4 to 135.0), compared to reference group, controlling for age, gender, parental allergy history, skin prick test, and environmental tobacco smoke (ETS) exposure. Interaction was observed between bronchiolitis before 2 years old and low socioeconomic status on children's bronchial hyperreactivity (p-interaction=0.025). Conclusions: This study showed that bronchiolitis diagnosed before 2 years of age and low socioeconomic status interacted on children's bronchial hyperreactivity. Prevention of acute respiratory infection in early childhood in low socioeconomic status is important to prevent BHR as a precursor of asthma.