• Clinical Endoscopy
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• v.57 no.1
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• pp.112-121
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• 2024

Background/Aims: Since the usefulness of neoadjuvant chemo(radiation) therapy (NAT) for pancreatic cancer has been demonstrated, recurrent biliary obstruction (RBO) in patients with pancreatic cancer with a fully covered self-expandable metal stent (FCSEMS) during NAT is expected to increase. This study investigated the impact of sarcopenia on RBO in this setting. Methods: Patients were divided into normal and low skeletal muscle index (SMI) groups and retrospectively analyzed. Patient characteristics, overall survival, time to RBO (TRBO), stent-related adverse events, and postoperative complications were compared between the two groups. A Cox proportional hazard model was used to identify the risk factors for short TRBO. Results: A few significant differences were observed in patient characteristics, overall survival, stent-related adverse events, and postoperative complications between 38 patients in the normal SMI group and 17 in the low SMI group. The median TRBO was not reached in the normal SMI group and was 112 days in the low SMI group (p=0.004). In multivariate analysis, low SMI was the only risk factor for short TRBO, with a hazard ratio of 5.707 (95% confidence interval, 1.148-28.381; p=0.033). Conclusions: Sarcopenia was identified as an independent risk factor for RBO in patients with pancreatic cancer with FCSEMS during NAT.

• The korean journal of orthodontics
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• v.28 no.4 s.69
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• pp.581-589
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• 1998

In order to correct a maxillofacial-skeletal disharmony successfully and achieve a favorable facial profile, orthodontic treatment must begin at pubertal growth spurt. Therefore predicting the pubertal growth pattern and evaluating the growth potential is very important. For an orthodontist, estimating skeletal maturity in relation to one's personal growth spurt is essential and it must be considered into the treatment. The objective of this study was to find out whether there was a difference in menacheal age among different malocclusion groups and to evaluate the skeletal maturity at menarche. The subjects were 64 Class I malocclusion patients, 51 Class II patients and 38 Class III patients. Skeletal maturity was estimated from handwrist radiographs of these patients. Handwrist radiographs were taken between 3 months before and after the menarche. The results were as follows. 1. The mean chronologic age of menarche was $12.50{\pm}1.01$ years. 2. For the Class I malocclusion group the mean age of menarche was $12.36{\pm}1.04$ years, for Class II $12.81{\pm}1.03$ years and for Class III $12.32{\pm}0.82$ years. According to these results Class II malocclusion patients started mensturation later than Class I and Class III malocclusion patients. 3. No difference was found considering the skeletal maturity at menarche among the malocclusion groups. 4. The skeletal maturity index at menarche was SMI 7 for $45.10\%$, SMI 8 for $27.25\%$, SMI 9 for $10.46\%$, SMI 6 for $7.84\%$, SMI 10 for $7.84\%$ and SMI 5 for $1.31\%$ patients. 5. Statistically there was a significant correlation between skeletal maturity estimated by handwrist radiographs and menacheal age(p<0.05, r=0.25430).

• KSCE Journal of Civil and Environmental Engineering Research
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• v.26 no.4B
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• pp.345-354
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• 2006

Drought brings on long term damage in contrast to flood, on economic loss in the region, and on ecologic and environmental disruptions. Drought is one of major natural disasters and gives a painful hardship to human beings. So we have tried to quantify the droughts for reducing drought damage and developed the drought indices for drought monitoring and management. The Palmer's drought severity index (PDSI) is widely used for the drought monitoring but it has the disadvanges and limitations in that the PDSI is estimated by considering just climate conditions as pointed out by many researchers. Thus this study uses the SWAT model which can consider soil conditions like soil type and land use in addition to climate conditions. We estimate soil water (SW) and soil moisture index (SMI) by SWAT which is a long term runoff simulation model. We apply the SWAT model to Soyang dam watershed for SMI estimation and compare SMI with PDSI for drought analysis. Say, we calibrate and validate the SWAT model by daily inflows of Soyang dam site and we estimate long term daily soil water. The estimated soil water is used for the computation of SMI based on the soil moisture deficit and we compare SMI with PDSI. As the results, we obtained the determination coefficient of 0.651 which means the SWAT model is applicable for drought monitoring and we can monitor drought in more high resolution by using GIS. So, we suggest that SMI based on the soil moisture deficit can be used for the drought monitoring and management.

• Korean Journal of Radiology
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• v.20 no.5
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• pp.759-772
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• 2019

Objective: To investigate the value of ultrasound (US) microflow assessment in distinguishing malignant from benign solid breast masses as well as the association between US parameters and histologic microvessel density (MVD). Materials and Methods: Ninety-eight breast masses (57 benign and 41 malignant) were examined using Superb Microvascular Imaging (SMI) and contrast-enhanced US (CEUS) before biopsy. Two radiologists evaluated the quantitative and qualitative vascular parameters on SMI (vascular index, morphology, distribution, and penetration) and CEUS (time-intensity curve analysis and enhancement characteristics). US parameters were compared between benign and malignant masses and the diagnostic performance was compared between SMI and CEUS. Subgroup analysis was performed according to lesion size. The effect of vascular parameters on downgrading Breast Imaging Reporting and Data System (BI-RADS) category 4A masses was evaluated. The association between histologic MVD and US parameters was analyzed. Results: Malignant masses were associated with a higher vascular index (15.1 ± 7.3 vs. 5.9 ± 5.6), complex vessel morphology (82.9% vs. 42.1%), central vascularity (95.1% vs. 59.6%), penetrating vessels (80.5% vs. 31.6%) on SMI (all, p < 0.001), as well as higher peak intensity (37.1 ± 25.7 vs. 17.0 ± 15.8, p < 0.001), slope (10.6 ± 11.2 vs. 3.9 ± 4.2, p = 0.001), area (1035.7 ± 726.9 vs. 458.2 ± 410.2, p < 0.001), hyperenhancement (95.1% vs. 70.2%, p = 0.005), centripetal enhancement (70.7% vs. 45.6%, p = 0.023), penetrating vessels (65.9% vs. 22.8%, p < 0.001), and perfusion defects (31.7% vs. 3.5%, p < 0.001) on CEUS (p ≤ 0.023). The areas under the receiver operating characteristic curve (AUCs) of SMI and CEUS were 0.853 and 0.841, respectively (p = 0.803). In 19 masses measuring < 10 mm, central vascularity on SMI was associated with malignancy (100% vs. 38.5%, p = 0.018). Considering all benign SMI parameters on the BI-RADS assessment, unnecessary biopsies could be avoided in 12 category 4A masses with improved AUCs (0.500 vs. 0.605, p < 0.001). US vascular parameters associated with malignancy showed higher MVD (p ≤ 0.016). MVD was higher in malignant masses than in benign masses, and malignant masses negative for estrogen receptor or positive for Ki67 had higher MVD (p < 0.05). Conclusion: US microflow assessment using SMI and CEUS is valuable in distinguishing malignant from benign solid breast masses, and US vascular parameters are associated with histologic MVD.

• Nutrition Research and Practice
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• v.15 no.2
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• pp.203-212
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• 2021

BACKGROUND/OBJECTIVES: The branched-chain amino acids (BCAA), including isoleucine, leucine, and valine, promote muscle protein synthesis. However, obesity may interfere with protein synthesis by dysregulating mitochondrial function in the muscles. This study aimed to examine the association between dietary intake levels of BCAA and skeletal muscle mass index (SMI) in middle-aged participants, and the effect of obesity/abdominal obesity on this association. SUBJECTS/METHODS: The data of 3,966 men and women aged 50-64 years who participated in the 2008-2011 Korea National Health and Nutrition Examination Survey were analyzed. Intake levels of energy-adjusted dietary amino acids were obtained using a 24-hour dietary recall. SMI was calculated by dividing the appendicular skeletal muscle mass by body weight (kg) and multiplying the result by 100%. Multivariable general linear models were used to analyze the association of dietary BCAA intake levels with SMI. RESULTS: The beneficial effects of energy-adjusted dietary BCAA intakes on SMI were greater in the non-obesity/non-abdominal obesity groups; however, no significant associations were observed in the obesity/abdominal obesity groups (P > 0.05). CONCLUSIONS: Healthy weight and sufficient intake of dietary BCAA are recommended to maintain muscle mass.

• Annals of Geriatric Medicine and Research
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• v.22 no.4
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• pp.194-199
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• 2018

Background: The aim of this study was to examine the correlation between the number of remaining natural teeth (NRT) and the appendicular skeletal muscle mass index (SMI) in older adults. Methods: This study was based on data from the 2008-2010 Korea National Health and Nutritional Examination Surveys. The participants were 2,378 older participants (984 men and 1,394 women) aged over 65 years. Survey dentists conducted oral health examinations, and ASM was measured using dual-energy X-ray absorptiometry. Results: The participants with $NRT{\geq}20$ had more ASM and SMI than those with NRT<20 in both sexes. SMI was correlated with NRT in men (r=0.018, p<0.001) and in women (r=-0.007, p<0.001). The positive correlation between the NRT and SMI remained significant in men even after adjusting for age, marital status, income, smoking, drinking, physical activity, protein intake, energy intake, calcium intake, body mass index, fasting blood glucose level, medications, and prostheses (${\beta}=0.011$, p=0.001). In women, the correlation disappeared after adjustment for smoking, alcohol, physical activity, protein intake, energy intake, calcium intake, marital status, income, fasting basal glucose, medication administration, and prostheses. Conclusion: This study showed a correlation between NRT and SMI in those ${\geq}65$ years of age in Korea. The relationship persisted in men, but not in women, even after adjusting for confounders.

• The Journal of the Acoustical Society of Korea
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• v.12 no.2E
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• pp.47-62
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• 1993

SMI 방법은 수치적인 불안정성과 아울러 많은 계산량을 갖는다. 본 논문에서는 역 공분산 행렬의 Cholesky 분할을 이용하여 SMI 방법보다 효율적인 방법을 제안한다. 제안한 방법에서는 적응 빔 형상과 검출이 하나의 구조로 실현되며 이에 피룡한 역 공분산 행렬의 Cholesky factor는 secondary 입력으로부터 GS 프로세서를 이용하여 추정한다. 제안한 구조의 중요한 특징은 공분산 행렬과 Cholesky factor를 직접 구할 필요가 없다는 점이며, 또한 GS 프로세서의 장점을 이용한 systolic 구조를 사용함으로써 효율적인 계산을 수행할 수 있다. 모의 실험을 통하여 제안한 방법의 성능과 SMI 방법의 성능을 서로 비교하였다. 또한 nonhomogeneous 환경에서 동작하기 위한 방법이 제시되었으며, 아울러 계산량이 많은 GS 구조의 단점을 극복하기 위해 lattice-GS 구조를 이용하는 방법을 제안하였다.

• Proceedings of the Korea Information Processing Society Conference
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• 2014.04a
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• pp.416-419
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• 2014

스미싱(SMiShing) 공격은 문자메시지(SMS)를 이용하여 정보를 유출하거나 타인에게 피해를 주는 행위를 일컫는다. 본 논문에서는 공격자의 공격유형에 따라 스미싱을 "직접 정보 유출", "파밍/피싱 사이트 유도", "악성어플리케이션 다운로드 유도"로 분류하였고 스미싱 공격의 시나리오를 통해 스미싱 공격을 표현하였다. 그 후 스미싱 방지 기술 동향을 파악을 위한 기존의 대응 기법들을 조사를 하고 기존의 스미싱 탐지 기법인 URL 검사와 APK 파일 분석 기법을 접목시킨 스미싱 탐지 모델을 제안한다.

• Journal of Music and Human Behavior
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• v.17 no.2
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• pp.29-56
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• 2020

The purpose of this study was to develop and validate an imagery-focused music listening program for improving emotion regulation among infertile women. For the program development in this study, the literature on emotional issues and coping strategy of infertile women was analyzed to establish theoretical foundation; and the literature on Supportive Music and Imagery (SMI) was analyzed to identify intervention components. Based on the established theoretical framework, the program was developed and finalized after evaluation of validity by four SMI professionals. The developed program was found to systematically target changes in emotions in the step-wise process of discovery, reinforcement, and affirmation of positive emotional resources. The list of music for future use was also identified and presented after systematic analysis of musical features in relation to valence and arousal of emotions. The imagery-focused music listening program was an initial approach to infertile women with SMI, which indicates the possibility of extended application for broadened clinical population.

• Korean Journal of Radiology
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• v.22 no.2
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• pp.189-197
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• 2021

Objective: Muscle depletion in patients undergoing liver transplantation affects the recipients' prognosis and therefore cannot be overlooked. We aimed to evaluate whether changes in muscle and fat mass during the preoperative period are associated with prognosis after deceased donor liver transplantation (DDLT). Materials and Methods: This study included 72 patients who underwent DDLT and serial computed tomography (CT) scans. Skeletal muscle index (SMI) and fat mass index (FMI) were calculated using the muscle and fat area in CT performed 1 year prior to surgery (1 yr Pre-LT), just before surgery (Pre-LT), and after transplantation (Post-LT). Simple aspects of serial changes in muscle and fat mass were analyzed during three measurement time points. The rate of preoperative changes in body composition parameters were calculated (preoperative ΔSMI [%] = [SMI at Pre-LT - SMI at 1 yr Pre-LT] / SMI at Pre-LT x 100; preoperative ΔFMI [%] = [FMI at Pre-LT - FMI at 1 yr Pre-LT] / FMI at Pre-LT x 100) and assessed for correlation with patient survival. Results: SMI significantly decreased during the preoperative period (mean preoperative ΔSMI, -13.04%, p < 0.001). In the multivariable analysis, preoperative ΔSMI (p = 0.016) and model for end-stage liver disease score (p = 0.011) were independent prognostic factors for overall survival. The mean survival time for patients with a threshold decrease in the preoperative ΔSMI (≤ -30%) was significantly shorter than for other patients (p = 0.007). Preoperative ΔFMI was not a prognostic factor but FMI increased during the postoperative period (p = 0.009) in all patients. Conclusion: A large reduction in preoperative SMI was significantly associated with reduced survival after DDLT. Therefore, changes in muscle mass during the preoperative period can be considered as a prognostic factor for survival after DDLT.