• The Bulletin of The Korean Astronomical Society
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• v.39 no.2
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• pp.52-52
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• 2014

It is widely accepted that the evolution of galaxies is accelerated in dense environments. According to recent studies, however, the evolution by direct interactions between galaxies is known to be most active in a galaxy group rather than in a galaxy cluster. In particular, the central galaxy in a group is closely related to its satellites in the properties such as morphology, color and star formation rate, because those galaxies evolve together in a small-scale environment. Currently, however, it is not yet studied well whether such conformity between bright galaxies and their faint companions remains after a galaxy group falls into a galaxy cluster. Recently, Lee et al. (2014) have found that the colors of bright galaxies show a measurable correlation with the mean colors of faint companions around them in WHL J085910.0+294957, a galaxy cluster at z = 0.3, which may be the vestige of infallen groups in the cluster. As a follow-up study, we study Abell 2744, an ongoing cluster-cluster merger at z = 0.308, using the HST Frontier Fields Survey data. The cluster members are selected based on the distributions of color, size and concentration along magnitude. The correlation in color between bright galaxies and their companions is not found in the full area of Abell 2744. However, when the area is limited to the southeastern part of the Abell 2744 image, the mean color of faint companions shows marginal dependence (> $2{\sigma}$ to Bootstrap uncertainties) on the color of their adjacent bright galaxy. We discuss the implication of these results, focusing on their dependence on local environments.

• Journal of Agricultural Extension & Community Development
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• v.25 no.2
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• pp.99-110
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• 2018

Research confirms that healthful benefits accrued when people connect with nature and insect by viewing and interacting with them. Insect rearing is easy, relatively inexpensive, and can breed small space. This study aimed to investigate the physiological effects of animal assisted activity using insect(Oriental garden cricket) with diets and a rearing manual. The group of insect activity whose ages ranged from 65 to 82 years old that attending a community center in Daegu, Korea, were enrolled in the study between April and May 2014. The collected data was analyzed using qualitative analysis. Qualitative study is utilized to explore mental models, and their linguistic, affective, cognitive, social and cultural significance. The result showed that people-insect interactions promote well being of the elders, and the important aspect of insect activity aids in improvements in their social, emotional and cognitive functioning which were enhancing life satisfaction, reducing loneliness and increasing activities of daily life.

• Proceedings of the Korean Society of Food Science and Nutrition Conference
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• 2004.11a
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• pp.17-23
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• 2004

Not all individuals respond identically, or at times in the same direction, to dietary interventions. These inconsistencies likely arise because of diet and genomic interactions (nutrigenomics effects). A host of factors may influence the response to bioactive food components including specific polymorphisms (nutrigenetic effect), DNA methylation patterns and other epigenomic factors (nutritional epigenomic effects), capacity to induce anuo. suppress specific mRNA expression and patterns (nutritional transcriptomics), the occurrence and activity of proteins (proteomic effects), and/or the dose and temporal changes in cellular small molecular weight compounds will not only provide clues about specificity in response to food components, but assist in the identification of surrogate tissues and biomarkers that can predict a response. While this 'discovery' phase is critical for defining mechanisms and targets, and thus those who will benefit most from intervention, its true usefulness depends on moving this understanding into 'development' (interventions for better prevention, detection, diagnosis, and treatment) and a 'delivery' phase where information is provided to those most in need. It is incumbent on those involved with food and nutrition to embrace the 'omics' that relate to nutrition when considering not only the nutritional value of foods and their food components, but also when addressing acceptability and safety. The future of 'Nutrigenomics and Health Promotion' depends on the ability of the scientific community to identity appropriate biomarkers and susceptibility variants, effective communications about the merits of such undertakings with the health care community and with consumers, and doing all of this within a responsible bioethical framework.

• Bulletin of the Korean Chemical Society
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• v.16 no.6
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• pp.547-552
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• 1995

As an extension to the Kramers' restricted Hartree-Fock (KRHF) method [J. Comp. Chem., 13, 595 (1992)], we have implemented the Kramers' restricted configuration interaction (KRCI) program in order to calculate excited states as well as the ground state of polyatomic molecules containing heavy atoms. This KRCI is based on determinants composed of the two-component molecular spinors which are generated from KRHF calculations. The Hamiltonian employed in the KRHF and KRCI methods contains most of all the important relativistic effects including spin-orbit terms through the use of relativistic effective core potentials (REP). The present program which is limited to a small configuration space has been tested for a few atoms and molecules. Excitation energies of the group 14 and 16 elements calculated using the present KRCI program are in good accordance with the spectroscopic data. Calculated excitation energies for many Rydberg states of K and Cs indicate that spin-orbit terms in the REP, which are derived for the ground state, are also reliable for the description of highly excited states. The electronic states of the polyatomic molecule CH3I are probed from the molecular region to the dissociation limit. Test calculations demonstrate that the present KRCI is a useful method for the description of potential energy surface of polyatomic molecules containing heavy atoms.

• Korean Journal of Childcare and Education
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• v.17 no.2
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• pp.29-46
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• 2021

Objective: The purpose of this study is to examine young children's social experiences during COVID-19. In this study, social experiences are defined as children's social interactions and relationships, their educational experiences, and their daily life experiences in child care centers. Methods: Participants include nine child care teachers and fifteen young children. Data were collected through semi-structured interviews with individual teachers, interviews with young children, and small group storytelling activities with young children. Results: The main findings in exploring meanings and implications of childcare consulting were as follows. First, childcare consulting was recognized as a process of learning about changes through mutual relationships. Second, the different ways to practice childcare consulting, the formation of the learning culture of an organization to help experience collective intelligence, the process of finding various solutions through mutual communication, and the improvement of childcare teachers' professional capabilities while reflecting the current times and context were all investigated. Conclusion/Implications: Given the findings of the study, the importance of childcare consulting, and the ways to establish its systems were discussed.

• Journal of Information Technology Applications and Management
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• v.28 no.6
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• pp.117-132
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• 2021

Based on the core value of the Q&A community, the contribution of knowledge and information has a great impact on users' community evaluation. As a small social group, the relationships and interactions among community members are quickly formed through information technology. As such, the cognitive evaluation of the relationship between community members will have an impact on the intention of information contribution. This research builds on the previous research based on the social exchange theory and establishes a dual model of swift guanxi in examining the relationship between guanxi and continuous knowledge contribution. In the current study, 305 survey questionnaires were used and 249 valid questionnaires were used for analysis. The analysis results are as follows: First, information support has a positive impact on dedication-based swift guanxi. While hypothesis between information support and constraint-based swift guanxi was not be supported. Second, emotional support has a positive impact on the formation of swift guanxi from a dual perspective. Third, the swift guanxi from the dual perspective has a positive impact on the intention of continuous knowledge contribution. Finally, although personal involvement has an adjustment effect, it is a downward adjustment effect, hypotheses are not supported. The current study offers theoretical and practical implications in field of knowledge management, specifically knowledge contribution in the virtual community.

• Journal of The Korean Association For Science Education
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• v.26 no.3
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• pp.385-392
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• 2006

This study investigated the effects of weekly reports as a method for encouraging student questions in middle school science instruction by focusing on student conceptual understanding, achievement, concept map, and perceptions of weekly reports. Seventh graders (N=211) from a middle school were assigned to control and weekly reports (WR) groups. All students were taught about the 'three states of matter', the 'motion of molecules', and the 'change of states and thermal energy' for eighteen class hours. Students in the WR group were required to write weekly reports for six of those periods. Results revealed that conception test scores for the WR group were significantly higher than those for the control group. Compared conception test scores by learning strategy, students using a surface learning strategy in the WR group scored significantly higher than those in the control group. While students employing a deep learning strategy in the WR group also performed better than those in the control group, the difference was relatively small. The scores of an achievement test and a concept map test for the WR group were significantly higher than those for the control group. However, there were no significant interactions between instruction and students' learning strategy in the two variables. It was also found that most students in the WR group positively perceived weekly reports.

• Journal of Microbiology and Biotechnology
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• v.30 no.9
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• pp.1436-1442
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• 2020

Amylosucrase (ASase, E.C. 2.4.1.4) is capable of efficient glucose transfer from sucrose, acting as the sole donor molecule, to various functional acceptor compounds, such as polyphenols and flavonoids. An ASase variant from Deinococcus geothermalis, in which the 226^th alanine is replaced with asparagine (DgAS-A226N), shows increased polymerization activity due to changes in the flexibility of the loop near the active site. In this study, we further investigated how the mutation modulates the enzymatic activity of DgAS using molecular dynamics and docking simulations to evaluate interactions between the enzyme and phenolic compounds. The computational analysis revealed that the A226N mutation could induce and stabilize structural changes near the substrate-binding site to increase glucose transfer efficiency to phenolic compounds. Kinetic parameters of DgAS-A226N and WT DgAS were determined with sucrose and 4-methylumbelliferone (MU) as donor and acceptor molecules, respectively. The k_cat/K_m value of DgAS-A226N with MU (6.352 mM^-1min^-1) was significantly higher than that of DgAS (5.296 mM^-1min^-1). The enzymatic activity was tested with a small phenolic compound, hydroquinone, and there was a 1.4-fold increase in α-arbutin production. From the results of the study, it was concluded that DgAS-A226N has improved acceptor specificity toward small phenolic compounds by way of stabilizing the active conformation of these compounds.

• Asian-Australasian Journal of Animal Sciences
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• v.21 no.6
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• pp.853-860
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• 2008

This experiment was conducted to study the effects of chromium (Cr), dietary crude protein (CP) level and potential interactions between these two factors on growth rate and carcass response, insulin activity and lipid metabolism in lambs. Forty-eight, 9-week-old weaned lambs (Dorper$\times$Small-tail Han sheep, mean initial body weight = $22.96kg{\pm}2.60kg$) were used in a $2{\times}3$ factorial arrangement of supplemental Cr (0 ppb, Cr0; 400 ppb, Cr1; or 800 ppb, Cr2 from chromium yeast) and CP levels (157 g/d to 171 g/d for each animal, LP; or 189 g/d to 209 g/d for each animal, HP). Growth data and blood samples were collected at the beginning and end of the feed trial, after which the lambs were killed. Both Cr additive groups and the HP group increased final weight and average daily gain, especially the Cr1 and HP group (p<0.01). HP increased pelvic fat weight (p<0.05), fat thickness of the 10th rib (p<0.05), longissimus muscle area (p<0.01) and rate of deposition of intramuscular fat (p<0.01). Supplemental Cr decreased the rate of deposition of intramuscular fat (p<0.05). Fasting insulin level and the ratio of insulin to glucose were lower with Cr1 than other groups, but with no significant difference. Glucose concentration was not affected by any treatment. Nonesterified fatty acids increased in the Cr1 (p<0.05) and HP (p<0.05) conditions and there was a significant $Cr{\times}CP$ interaction (p<0.05). Cr1 decreased triglycerides (p<0.05) and total cholesterol (p = 0.151) and HP increased high-density lipoprotein cholesterol (p<0.05). Cr1 decreased lipoprotein lipase activity in subcutaneous adipose tissue (aLPL, p<0.05) and the ratio of aLPL to lipoprotein lipase activity in skeletal muscle (mLPL, p = 0.079). mLPL and hepatic lipase (hHL) were not affected by any treatment. In the present study, Cr had limited effects on growth rate and carcass response, whereas Cr and CP had some notable effects on plasma metabolites and enzyme activities. Cr has a potential effect on energy modulation between lipid and muscle tissue. In addition, few $Cr{\times}CP$ interactions were observed.

• YAKHAK HOEJI
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• v.53 no.5
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• pp.259-264
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• 2009

The present study was to investigate the effect of naringin, a flavonoid, on the pharmacokinetics of losartan in rats. Pharmacokinetic parameters of losartan in rats were determined after an oral administration of losartan (9 mg/kg) in the presence or absence of naringin (0.5, 2.5 and 10 mg/kg). The pharmacokinetic parameters of losartan were significantly altered by the presence of naringin compared with the control group (given losartan alone). Presence of naringin significantly (p<0.05, 2.5 mg/kg; p<0.01, 10 mg/kg) increased the area under the plasma concentration?time curve (AUC) of losartan by 43.7~63.0% and peak plasma concentration ($C_{max}$) of losartan by 31.7~45.5%. Consequently, the absolute bioavailability (AB) of losartan in the presence of naringin was 43.8~62.9%, which was enhanced significantly (p<0.05, p<0.01) compared to that in the oral control group (22.4%). The relative bioavailability (R.B.) of losartan increased by 1.44- to 1.63-fold in the presence of naringin. However, there was no significant change in the peak plasma concentration ($T_{max}$) and terminal half-life ($t_{1/2}$) of losartan in the presence of naringin. In conclusion, the presence of naringin significantly enhanced the oral bioavailability of losartan, implying that presence of naringin might be mainly effective to inhibit the cytochrome P450 (CYP)3A-mediated metabolism, resulting in reducing gastrointestinal and hepatic first-pass metabilism and Pglycoprotein (P-gp)-mediated efflux of losartan in small intestine. Concurrent use of naringin or naringin-containing dietary supplement with losartan should require close monitoring for potential drug interactions.