• The Journal of Korean Institute of Communications and Information Sciences
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• v.35 no.5B
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• pp.741-752
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• 2010

The ability to seamlessly switch between the macro networks and femtocell networks is a key driver for femtocell network deployment. The handover procedures for the integrated femtocell/macrocell networks differ from the existing handovers. Some modifications of existing network and protocol architecture for the integration of femtocell networks with the existing macrocell networks are also essential. These modifications change the signal flow for handover procedures due to different 2-tier cell (macrocell and femtocell) environment. The handover between two networks should be performed with minimum signaling. A frequent and unnecessary handover is another problem for hierarchical femtocell/macrocell network environment that must be minimized. This work studies the details mobility management schemes for small and medium scale femtocell network deployment. To do that, firstly we present two different network architectures for small scale and medium scale WCDMA femtocell deployment. The details handover call flow for these two network architectures and CAC scheme to minimize the unnecessary handovers are proposed for the integrated femtocell/macrocell networks. The numerical analysis for the proposed M/M/N/N queuing scheme and the simulation results of the proposed CAC scheme demonstrate the handover call control performances for femtocell environment.

• The Journal of Korean Institute of Next Generation Computing
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• v.13 no.5
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• pp.104-112
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• 2017

The CRE (Cell Range Expansion) that selects the small cell with more efficient uplink resources has been developed by 3GPP to relieve the problem of the traffic imbalance due to the power differences between macro and small cells in HetNet. In addition, ABS (Almost Blank Subframes) has been proposed to resolve the signal interference problem due to the operation CREs. This paper proposes an effective method to calculate the ABS ratio by considering the proportion of the number of UEs in CRE and macro cell ranges, as well as the number of small cells in a macro cell. The proposed method has been implemented on the LTESim simulator, and compared with previously proposed methods. The experimental results show that the proposed method can improve the throughput and packet loss ratio performances. In particular, it is also shown that CRE bias values affect those performances, and there exist effective CRE bias values to derive the best performances.

• Journal of Communications and Networks
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• v.13 no.4
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• pp.327-338
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• 2011

With the incitation to reduce power consumption and the aggressive reuse of spectral resources, there is an inevitable trend towards the deployment of small-cell networks by decomposing a traditional single-tier network into a multi-tier network with very high throughput per network area. However, this cell size reduction increases the complexity of network operation and the severity of cross-tier interference. In this paper, we consider a downlink two-tier network comprising of a multiple-antenna macrocell base station and a single femtocell access point, each serving multiples users with a single antenna. In this scenario, we treat the following beamforming optimization problems: i) Total transmit power minimization problem; ii) mean-square error balancing problem; and iii) interference power minimization problem. In the presence of perfect channel state information (CSI), we formulate the optimization algorithms in a centralized manner and determine the optimal beamformers using standard convex optimization techniques. In addition, we propose semi-decentralized algorithms to overcome the drawback of centralized design by introducing the signal-to-leakage plus noise ratio criteria. Taking into account imperfect CSI for both centralized and semi-decentralized approaches, we also propose robust algorithms tailored by the worst-case design to mitigate the effect of channel uncertainty. Finally, numerical results are presented to validate our proposed algorithms.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.40 no.12
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• pp.2539-2548
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• 2015

Overcoming inter-cell interference and spectrum scarcity are major issues in heterogeneous cellular networks. Static Frequency reuse schemes have been proposed as an effective way to manage the spectrum and reduce ICI(Inter cell Interference) in cellular networks. In a kind of static frequency reuse scheme, the allocations of transmission power and subcarriers in each cell are fixed prior to system deployment. This limits the potential performance of the static frequency reuse scheme. Also, most of dynamic frequency reuse schemes did not consider small cell and the network environment when the traffic load of each cell is heavy and non-uniform. In this paper, we propose an inter-cell resource allocation algorithm that dynamically optimizes subcarrier allocations for the multi-cell heterogeneous networks. The proposed dynamic frequency reuse scheme first finds the subcarrier usage in each cell-edge by using the exhaustive search and allocates subcarrier for all the cells except small cells. After that it allocates subcarrier for the small cell and then iteratively repeats the process. Proposed dynamic frequency reuse scheme performs better than previous frequency reuse schemes in terms of the throughput by improving the spectral efficiency due to it is able to adapt the network environment immediately when the traffic load of each cell is heavy and non-uniform.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.21 no.1
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• pp.131-143
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• 1996

In this paper, we propose the improved structure of fully interconnected ATM Switch to develop the small sized switch element and represent practical implementation of switch network. As the part II of the full study about structure and implementation of fully interconnected ATM Switch, this paper especially describes the implementation of an ATM switching element with 8 input port and 8 output port at 155 Mbits/sec each. The single board switching element is used as a basic switching block in a small sized ATm switch for ATM LAN Hub and customer access node. This switch has dedicated bus in 12 bit width(8 bit data + 4 bit control signal) at each input and output port, bit addressing and cell filtering scheme. In this paper, we propose a practical switch architecture with fully interconnected buses to implement a small-sized switch and to provide multicast function withoutany difficulty. The design of switching element has become feasible using advanced CMOS technology and Embedded Gate Array technology. And, we also represent Application Specific Integrated Circuit(ASIC) of Switch Output Multiplexing Unit(SOMU) and 12 layered Printed Circuit Board for interconnection network of switch.

• Journal of Internet Computing and Services
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• v.23 no.5
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• pp.25-31
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• 2022

In ultra dense networks (UDNs), macro user equipments (MUEs) have significant interference from small-cell access points (SAPs) since a number of SAPs are deployed in the coverage of macro base stations of 5G mobile communication systems. In this paper, we propose a dynamic channel assignment scheme to increase the performance of MUEs for the uplink of UDNs even though the number of SAPs is increased. The target of the proposed dynamic channel assignment scheme is that the signal-to-interference and noise ratio (SINR) of MUEs is above a given SINR threshold assigning different subchannels to SUEs from those of MUEs. Simulation results show that the proposed dynamic channel assignment scheme outperforms others in terms of the mean MUE capacity even though the mean SUE capacity is decreased a little lower.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.8
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• pp.4485-4494
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• 2013

Epidermal growth factor receptor (EGFR) is considered to be one of the key driver genes in non-small cell lung cancer (NSCLC). Several clinical trials have shown great promise of EGFR tyrosine kinase inhibitors (TKIs) in the first-line treatment of NSCLC. Many advances have been made in the understanding of EGFR signal transduction network and the interaction between EGFR and tumor microenvironment in mediating cancer survival and development. The concomitant targeted therapy and radiation is a new strategy in the treatment of NSCLC. A number of preclinical studies have demonstrated synergistic anti-tumor activity in the combination of EGFR inhibitors and radiotherapy in vitro and in vivo. In the present review, we discuss the rationale of the combination of EGFR inhibitors and radiotherapy in the treatment of NSCLC.

• Radiation Oncology Journal
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• v.35 no.1
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• pp.16-24
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• 2017

Locally advanced non-small cell lung cancer (LA-NSCLC) is composed of heterogeneous subgroups that require a multidisciplinary team approach in order to ensure optimal therapy for each patient. Since 2010, the National Comprehensive Cancer Network has recommended chemoradiation therapy (CRT) for bulky mediastinal disease and surgical combination for those patients with single-station N2 involvement who respond to neoadjuvant therapy. According to lung cancer tumor boards, thoracic surgeons make a decision on the resectability of the tumor, if it is determined to be unresectable, concurrent CRT (CCRT) is considered the next choice. However, the survival benefit of CCRT over sequential CRT or radiotherapy alone carries the risk of additional toxicity. Considering severe adverse events that may lead to death, fit patients who are able to tolerate CCRT must be identified by multidisciplinary tumor board. Decelerated approaches, such as sequential CRT or high-dose radiation alone may be a valuable alternative for patients who are not eligible for CCRT. As a new treatment strategy, investigators are interested in the application of the innovative radiation techniques, trimodality therapy combining surgery after high-dose definitive CCRT, and the combination of radiation with targeted or immunotherapy agents. The updated results and on-going studies are thoroughly reviewed in this article.

• The Journal of Korea Institute of Information, Electronics, and Communication Technology
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• v.11 no.4
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• pp.394-400
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• 2018

A heterogenous network is the one of key technologies for 5G, where one cell is divided into small cells in order to extend coverage and support high data rates. Divided cells aggravates the intercell interference problem as the cell edge increases. In order to avoid the intercell interference, it is the best to allocate the different spectrum for each cells. However, it also decreases the spectral efficiency. Therefore, the trade-off between the spectral efficiency gain and the signal quality loss by the interference should be considered for an efficient spectrum sharing in the heterogenous network. The adaptive modulation is the method to change the transmitted bit according to the channel quality, which is adopted as the standard in the most practical communication systems. It should be considered to applied the performance analysis into the practical systems. In this paper, the overall cell data rates is analyzed for the heterogenous network under the adaptive modulation. The Monte Carlo simulation results verify the correctness of the analysis.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.4
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• pp.1477-1482
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• 2012

Squamous cell carcinoma and adenocarcinoma are the major histological types of non-small cell lung cancer. Because they differ on the basis of histopathological and clinical characteristics and their relationship with smoking, their etiologies may be different; for example, different tumor suppressor genes may be related to the genesis of each type. We used microarray data to construct three regulatory networks to identify potential genes related to lung adenocarcinoma and squamous cell carcinoma and investigated the similarity and specificity of them. In the network, some of the observed transcription factors and target genes had been previously proven to be related to lung adenocarcinoma and squamous cell carcinoma. We also found some new transcription factors and target genes related to SCC. The results demonstrated that regulatory network analysis is useful in connection analysis between lung adenocarcinoma and squamous cell carcinoma.