• 한국임상수의학회지
• /
• 제27권2호
• /
• pp.179-182
• /
• 2010

경추 척추척수증(CSM)은 소형 품종 견에서 드물게 발병하는 질병이다. 두 마리의 중성화 하지 않은 페키니즈(체중 5 kg 이하)가 경부 통증과 마비성 보행을 주증으로 내원하였다. 영상 진단을 통해 척추 불안정성에 의한 CSM으로 진단하고, 배쪽 창냄술과 해면질골 이식, 외고정을 조합한 방법을 적용하였다. 수술 후 임상 증상이 현저하게 개선되었고 합병증이나 재발은 없었다. 경추의 척추척수증이 있는 소형 품종 견에서 배쪽 창냄술을 통한 감압과 골 유합을 통한 안정화를 조합한 방법은 효과적인 치료법임을 확인하였다.

• 한국임상수의학회지
• /
• 제33권6호
• /
• pp.340-345
• /
• 2016

The present study determined the normal reference ranges for the femoral and tibial joint orientation angles of small-breed dogs. For this purpose, 60 each of cadaveric canine femurs and tibias from normal small-breed dogs (Maltese, Poodle, Shih Tzu, Yorkshire Terrier) were examined with radiographs and photographs. Axial and frontal radiographs and photographs of each bone were obtained, from which anteversion and inclination angles, anatomic lateral proximal and distal femoral angles (aLPFA and aLDFA), mechanical lateral proximal and distal femoral angles (mLPFA and mLDFA), and mechanical medial proximal and distal tibial angles (mMPTA and mMDTA) were measured. The 95% CI for radiographic values of all femurs and tibiae were anteversion angle, $23.4-27.4^{\circ}$; inclination angle, $128.4-130.4^{\circ}$; aLPFA, $117.8-122.1^{\circ}$; aLDFA, $93.7-95.2^{\circ}$; mLPFA $113.8-117.3^{\circ}$; mLDFA $99.2-100.5^{\circ}$; mMPTA $96.8-98.5^{\circ}$; mMDTA $89.4-90.7^{\circ}$. The Maltese had a larger anteversion angle than the Poodle and the Yorkshire Terrier and a larger mLPFA than the Poodle. In the comparison between the radiographs and the photographs, significant differences were found in the anteversion angle, mLPFA, mMPTA, and mMDTA. The established normal reference values might be useful for determining whether a valgus or varus deformity of the femur or the tibia is present and if so, the degree of angular correction needed.

• Journal of Veterinary Science
• /
• 제23권4호
• /
• pp.53.1-53.9
• /
• 2022

Background: Problems associated with using inhalational anaesthesia are numerous in veterinary anaesthesia practice. Decreasing the amount of used inhalational anaesthetic agents and minimising of cardiorespiratory disorders are the standard goals of anaesthetists. Objective: This experimental study was carried out to investigate the sparing effect of intravenous tramadol, lidocaine, dexmedetomidine and their combinations on the minimum alveolar concentration (MAC) of sevoflurane in healthy Beagle dogs. Methods: This study was conducted on six beagle dogs. Sevoflurane MAC was determined by the tail clamp method on five separate occasions. The dogs received no treatment (control; CONT), tramadol (TRM: 1.5 mg kg^-1 intravenously followed by 1.3 mg kg^-1 h^-1), lidocaine (LID: 2 mg kg^-1 intravenously followed by 3 mg kg^-1 h^-1), dexmedetomidine (DEX: 2 ㎍ kg^-1 intravenously followed by 2 ㎍ kg^-1 h^-1), and their combination (COMB), respectively. Cardiorespiratory variables were recorded every five minutes and immediately before the application of a noxious stimulus. Results: The COMB treatment had the greatest sevoflurane MAC-sparing effect (67.4 ± 13.9%) compared with the other treatments (5.1 ± 25.3, 12.7 ± 14.3, and 40.3 ± 15.1% for TRM, LID, and DEX treatment, respectively). The cardiopulmonary variables remained within the clinically acceptable range following COMB treatment, although the mean arterial pressure was higher and accompanied by bradycardia. Conclusions: Tramadol-lidocaine-dexmedetomidine co-infusion produced a remarkable sevoflurane MAC-sparing effect in clinically healthy beagle dogs and could result in the alleviation of cardiorespiratory depression caused by sevoflurane. Cardiorespiratory variables should be monitored carefully to avoid undesirable side effects induced by dexmedetomidine.

• Maxillofacial Plastic and Reconstructive Surgery
• /
• 제15권2호
• /
• pp.129-136
• /
• 1993

The purpose of this study is to evaluate whether the ashed tooth powder is utilized as an alternative material of the implant. For this purpose the author performed the experimental study to investigate the tissue response of sintered toothash and its histocompatibility. Bony defects to expose the body of marrow, $1{\times}1cm$ in size, were created in the right and left mandibular body of mature dog, and then the ashed tooth powders were filled in right side and the blood clot was filled in the left side as an control. The dogs were sacrificed at 4th, 7th, and 16th week after implantation and histologic examination was performed. The results of this study were obtained as follows : 1. Any inflammatory response was not noted after implanting of the ashed tooth powder during the whole experimental period. 2. At 4th week, ashed tooth powders were surrounded by mature connective tissue. And we could observe hydroxyapatite crystal structure within the ashed tooth powder. 3. At 7th week, we could observe that macrophage phagocyted the small granules of ashed tooth powders. 4. At 16th week, the union with host bone by growth of new trabeculae was observed. And there were remnants of ashed tooth power within some of new trabeculae.

• 한국동물위생학회지
• /
• 제41권3호
• /
• pp.211-216
• /
• 2018

Heat stroke in a dog is a life-threatening syndrome characterized by a high body temperature over $41^{\circ}C$, by the central nervous system dysfunction, and by multiple organ dysfunction. A 11-month-old male American Pit Bull Terrier was presented to clarify the cause of death to diagnostic laboratory. This dog showed clinical signs such as high body temperature ($42^{\circ}C$), severe tachypnea, hematochezia, epistaxis and hemoptysis after transportation at hot summer time. At necropsy, there were hemorrhages in skin, serosa of stomach and small intestine, and also dark red fluid in lumen of intestine. Histopathologic examination revealed extensive hemorrhages in stomach, muscle, skin, and tongue. In microbiology, pathologic bacteria such as Pasteurella, Boedetella, Salmonella, Clostridium, and circulating virus in Korea such as CDV, CIV, CAV, CHV, CCV, CPIV were negative except CPV. There were many gross and microscopic lesions suggesting hest stroke while pathologic agents and related lesions were not detected. Therefore we diagnosed this case as heatstroke.

• 한국동물위생학회지
• /
• 제21권1호
• /
• pp.29-39
• /
• 1998

This study was carried out to investigate the prevalence of antibody against Toxoplasma gondii in the dog by Latex agglutination test and Indirect fluorescent antibody test. Two month-old dogs were infected intraperitoneally with T gondii to observe histopathological and immunohisto-chemical changes. Results obtained through this experiment were summarized as follows ; 1. Among the serum samples of 163 heads of the dog, 10 samples(6.1%) were positive. 2. In the sex, 6 heads (7.1%) out of 84 female dogs and 4 heads(5.1%) out of 79 male dogs were positive. However, there were no significant differences between the male and female. 3. Overall proportion of agreement between indirect fluorescent antibody and Latex agglutination test in 163 sera of dogs was 97.5%. 4. When 2 month-old dogs were infected intraperitoneally with T gondii, main clinical signs were intermittent fever, dyspnea, diarrhea. In general, the infected dogs recovered closely on the 11th day of post-inoculation. 5. At necropsy, petechial and ecchymotic hemorrages and swelling in small intestine, lung, spleen, liver and kidney were observed. 6. In histopathological observation, interstitial pneumonia, hyperemia and hemorrhages in lung were observed. Focal necrosis of hepatocytes, the neutrophil and basophil in the renal tubular epithelium were observed. 7. By immunohistochemical staining using Vectorstain ABC kit, the positive cells were recognized in the lung and the liver. 8. By indirect fluorescent antibody test, the Toxoplasma antibodies in the infected dogs were detected on the 15th day of postinoculation.

• Parasites, Hosts and Diseases
• /
• 제52권5호
• /
• pp.471-478
• /
• 2014

Trichomonad species inhabit a variety of vertebrate hosts; however, their potential zoonotic transmission has not been clearly addressed, especially with regard to human infection. Twenty-one strains of trichomonads isolated from humans (5 isolates), pigs (6 isolates), rodents (6 isolates), a water buffalo (1 isolate), a cow (1 isolate), a goat (1 isolate), and a dog (1 isolate) were collected in Indonesia and molecularly characterized. The DNA sequences of the partial 18S small subunit ribosomal RNA (rRNA) gene or 5.8S rRNA gene locus with its flanking regions (internal transcribed spacer region, ITS1 and ITS2) were identified in various trichomonads; Simplicimonas sp., Hexamastix mitis, and Hypotrichomonas sp. from rodents, and Tetratrichomonas sp. and Trichomonas sp. from pigs. All of these species were not detected in humans, whereas Pentatrichomonas hominis was identified in humans, pigs, the dog, the water buffalo, the cow, and the goat. Even when using the high-resolution gene locus of the ITS regions, all P. hominis strains were genetically identical; thus zoonotic transmission between humans and these closely related mammals may be occurring in the area investigated. The detection of Simplicimonas sp. in rodents (Rattus exulans) and P. hominis in water buffalo in this study revealed newly recognized host adaptations and suggested the existence of remaining unrevealed ranges of hosts in the trichomonad species.

• 한국의류산업학회지
• /
• 제20권2호
• /
• pp.219-225
• /
• 2018

The purpose of this study is to make an ideal dummy for adult Maltese with proper investigation of its character and direct measurement of dog body-shape. The results of the study are as follows; First, there were 6 factors to affect the characteristics of Maltese body in the analysis, which are size of body, leg shape, chest shape, leg thickness, body length, length between fore-legs. In the cluster analysis with the 6 factors there were two types of Maltese body. Type 1 has body characteristics with large body, thick leg, and small distance between front legs. Type 2 has average size of all factors including body size, leg thickness, and length between fore-legs. Second, type 2 was selected as a representative one to make a dummy reflected body shape of characteristics because it took 67.71% from entire considered factors and has average value in the measured size. The first dummy pattern was planned by copying the surface area of the representative body shape with the method of surgical tape. A dummy of single body with trunk and legs was made using 30's cotton cloth, polyester inside batting, compressed form PVC and metallic wire on the joint of trunk and legs to support dummy shape. The second pattern was made by correcting size difference of the pattern and adding the pattern of neck covering plate, metal magnetic button was inserted on the center of joint area of trunk and legs to make detachable legs for easy slip on and off the pet's wear.

• 약학회지
• /
• 제40권4호
• /
• pp.468-477
• /
• 1996

Vasopressin which is an antidiuretic hormone in human body produced the diuretic action in dog. This study was investigated in order to certify the diuretic action and to search out the mechanism of the action on the vasopressin. Vasopressin, when given in a dose of 10.0mU/kg, bolus+1.0mU/kg/min intravenously, exhibited the increase of urine flow(Vol), renal plasma flow(RPF), osmolar clearance (Cosm) and amounts of sodium and potassium excreted in urine ($E_{Na},\;E_K$), the decrease of reabsorption rate of sodium and potassium in renal tubules ($R_{Na},\;R_K$), and then elevated the mean arterial pressure(MAP). Vasopressin given in a increased dose to 30.0mU/kg, bolus+1.0mU/kg/min intravenously elicited the same aspect with that exhibited by a small dose in changes of Vol. and all renal function and potentiated the change rates, whereas this time MAP did not change at all when compared with control value. Vasopressin, when administered into a renal artery, did not induce the changes of Vol and all renal function in experimental (administered) kidney, but increased slightly the Vol, glomerular filtration rate(GFR), $E_{Na},\;and\;E_K$ expected the no change of $R_{Na}\;and\;R_K$ in the control (not administered) kidney. Vasopressin, when infused into carotid artery, showed the increase of Vol. GFR, $E_{Na},\;and\;E_K$ and no change of $R_{Na}\;and\;R_K$ in a dose of 1/5 of intravenous dose. Diuretic action of vasopressin administered into carotid artery was not influenced by renal denervation. Above results suggest that vasopressin produced diuretic action by hemodynamic changes in dogs. These hemodynamic changes may be mediated by central endogenous substances not associated with renal nerve.

• 한국임상수의학회지
• /
• 제32권1호
• /
• pp.108-111
• /
• 2015

7개월령 수컷 말티즈견이 1.5개월 동안 오른쪽 눈의 녹내장으로 치료를 받던 중에 내원하였다. 안검사에서 우안, 각막 천공, 홍채 탈출, 각막부종 및 혈관화가 관찰되었다. 안압은 오른쪽 눈이 33 mmHg, 왼쪽 눈이 19 mmHg이었다. 오른쪽 눈은 만성 녹내장, 각막 천공 및 홍채 탈출로 진단되었다. 그 눈은 실명하였으며 안구를 보존하기 위해 안내 보철물 삽입과 결막 플랩을 함께 적용하기로 하였다. 수술 후에 결막 플랩은 각막 천공 부위를 막고 안내 보철물을 적절하게 유지하였다. 수술 15개월 후에도 아무런 합병증 없었으며 보호자는 매우 만족하였다. 그러므로 안내 보철물과 결막 플랩의 병용 적용은 각막 천공으로 인한 녹내장의 치료에 이용될 수 있을 것이다.