• 대한전기학회:학술대회논문집
• /
• 대한전기학회 2004년도 하계학술대회 논문집 A
• /
• pp.397-399
• /
• 2004

A small-sized isolated 154kV transmission system could be brought out by a separation from whole network due to faults at transmission lines. For such system, where a fault occurs following a reclosing action, we Provided the basis for study to provide an effective load shedding scheme needed to the case of failure of reclosing action as well as the characteristic of reclosing action whether it succeeds or fails.

• 약학회지
• /
• 제40권4호
• /
• pp.468-477
• /
• 1996

Vasopressin which is an antidiuretic hormone in human body produced the diuretic action in dog. This study was investigated in order to certify the diuretic action and to search out the mechanism of the action on the vasopressin. Vasopressin, when given in a dose of 10.0mU/kg, bolus+1.0mU/kg/min intravenously, exhibited the increase of urine flow(Vol), renal plasma flow(RPF), osmolar clearance (Cosm) and amounts of sodium and potassium excreted in urine ($E_{Na},\;E_K$), the decrease of reabsorption rate of sodium and potassium in renal tubules ($R_{Na},\;R_K$), and then elevated the mean arterial pressure(MAP). Vasopressin given in a increased dose to 30.0mU/kg, bolus+1.0mU/kg/min intravenously elicited the same aspect with that exhibited by a small dose in changes of Vol. and all renal function and potentiated the change rates, whereas this time MAP did not change at all when compared with control value. Vasopressin, when administered into a renal artery, did not induce the changes of Vol and all renal function in experimental (administered) kidney, but increased slightly the Vol, glomerular filtration rate(GFR), $E_{Na},\;and\;E_K$ expected the no change of $R_{Na}\;and\;R_K$ in the control (not administered) kidney. Vasopressin, when infused into carotid artery, showed the increase of Vol. GFR, $E_{Na},\;and\;E_K$ and no change of $R_{Na}\;and\;R_K$ in a dose of 1/5 of intravenous dose. Diuretic action of vasopressin administered into carotid artery was not influenced by renal denervation. Above results suggest that vasopressin produced diuretic action by hemodynamic changes in dogs. These hemodynamic changes may be mediated by central endogenous substances not associated with renal nerve.

• 벤처창업연구
• /
• 제10권6호
• /
• pp.99-106
• /
• 2015

본 연구는 신발제조업체에 속하는 B산업을 대상으로 액션러닝을 이용한 학습조직에 관한 사례조사를 한다. 구체적인 학습조직 활동의 촉진을 위한 컨설팅 스킬로 액션러닝(action learning)기법을 적용한다. 액션러닝의 경우, 기업의 당면한 문제도 해결하고 프로그램에 참여하는 동안 구성원의 역량도 함께 강화되기 때문에 경영혁신도구로 활용도가 높으며, 불확실성이 높은 환경극복에 좋은 방법론으로 알려져 있다. 사례분석에서 컨설팅에서 기대한 효과가 학습조직의 회의특성에서 긍정적인 변화로 나타나고 있다. 따라서 중소기업의 학습조직 구축에 중요한 시사점을 액션러닝 방식의 컨설팅과정에서 도출할 수 있었다. 연구결과는 기업 내 학습조직의 지속적 운영을 위해서는 기업 환경과 전략을 고려한 학습조직 방향의 수립이 중요하며 새로운 학습조직 운영방법을 터득하여 실천하는 과정의 반복이 필요하다는 점을 제시한다.

• The Korean Journal of Physiology
• /
• 제16권2호
• /
• pp.119-128
• /
• 1982

The frog truncus arterious were studied with conventional glass microelectrode technique in order to elucidate the underlying mechanism of spontaneous pacemaker activity. The analyses were focussed on the ionic nature of pacemaker current by changing the concentrations of extracellular $K^+$ and, $Na^+$, or by using blockers of K- and Ca-current and chronotropic transmitters. 1) The action potential of the spontaneously active truncus arteriosus has some characteristic feature of maximal distolic potential ranged from -65 to -75 mV, resting potential from -45 to -50 mV and overshoot voltage about +30 mV, respectively. Duration of the action potential taken from rapid upstroke to maximal diastolic potential was about 600 msec. Usual discharge rate was $25{\sim}30/min$ at room temperature $(18{\sim}20^{\circ}C)$. 2) The sensitivity of the resting membrane potential to change extracellular potassium concentrations $(0{\sim}12\;mM)$ was relatively low. Transient hyperpolarization was appeared in the 12 mM K Ringer after 10 min exposure to 0 mM K and it could be related to Na-pump reactivation by high potassium. 3) Reduction of extracellular sodium concetrations diminished the amplitude and frequency of the action potential. In Ringer solution containing 30% Na (substituted by equimolar Tris), spontaneous activity stopped but reappeared as very slow and small action potential. There was no spotaneous activity in zero Na Ringer solution. 4) Caesium(10 mM), K-current blocker decreased the frequency of the action potential and also pacemaker depolarization. Manganese (2 mM) known to be Ca-current antagonist, blocked spontaneous activity completely. 5) Adrenaline and acetylcholine had no chronotropic effect. But adrenaline increased the duration of plateau phase and the magnitude of the action potential in the follower cell. It is concluded that K-, Na-and Ca-current components are involved in the genesis of spontaneous activity of the frog truncus arteriosus like cardiac pacemaker tissues. But the insensitivity of truncus arteriosus to adrenaline and acetylcholine indicates that there are some different control mechanisms of spontaneous rhythm in two tissues.

• 한국콘텐츠학회논문지
• /
• 제2권1호
• /
• pp.16-23
• /
• 2002

본 연구에서는 중소기업인들을 위한 디자인 교육 사이트의 부분으로서 I-business readiness 라는 이름으로 중소기업인들의 기존 사업을 Online을 통하여 확장하는 방법을 교육하는 컨텐츠를 개발하였으며 비즈니스 기획에 있어서의 디자인의 중요성을 강조하고 중소기업인들의 디자인에 대한 이해를 높이며 디자인을 사업에 잘 활용할 수 있는 방안을 제시하였다.

• Biomolecules & Therapeutics
• /
• 제9권1호
• /
• pp.26-32
• /
• 2001

This study was investigated about the effect of glibenclamide (GLY) which is $K^{+}$ channel blocker on renal function in rabbit, GLY, when given into the vein, produced the diuretic action accompanied with the increases of amounts of N $a^{+}$ and $K^{+}$ excreted into urine ( $E_{Na}$ , $E^{K}$), and then osmolar and negative free water clearances ( $C_{osm}$, $T^{C}$$_{H2O}$), fraction excretory rates of filtered N $a^{+}$ and $K^{+}$ ( $F_{Na}$ , $F_{K}$) and ratios of $E_{K}$ against $E_{Na}$ were augmented. Filtration fraction (FF) were reduced because renal plasma flow (RPF) were not changed but glomerular filtration rates (GFR) were diminished. GLY administered into a renal artery exhibited significant reduction of urine volume along with the decreases of GFR and RPF in only experimented kidney whereas changes of renal function was not observed in control kidney. GLY given intracerebroventricularly exhibited diuretic action along with the increase of $E_{Na}$ , $E_{K}$ and $F_{Na}$ , $F_{K}$ by small dose which was not affect on renal function when it given into the vein. Above results suggest that GLY given into the vein in rabbit produce the diuretic action by inhibition of electrolytes reabsorption in renal tubules through central function. function.n. function.ion.

• 생약학회지
• /
• 제15권3호
• /
• pp.121-127
• /
• 1984

Attempts were to investigate the effects of 'Bojungikgi-tang' on the digestive system, blood pressure and diuresis. The results showed that relaxing action was shown on the isolated ileum in mice and that strong antagonistic actions were seen on $BaCl_2$, acetylcholine and histamine-induced contraction of the ileum in mice and guinea-pigs that the relaxing effect of the intestinal smooth muscle was recognized. Inhibitory effects on transport rate in the small intestine of mice and castor oil-induced catharsis in mice were noted. Inhibitory action on the secretion of gastric juice, pH ascending effect and decreasing effect of the free acidity and total acidity were recognized. Continuous hypotensive action was seen, but when the vagus nerve was cut, hypotensive action was remarkably decreased. The diuretic effect was also recognized.

• 한국식품위생안전성학회지
• /
• 제18권4호
• /
• pp.171-176
• /
• 2003

누룩치, 고본, 당귀 및 산초의 ethanol ext.는 자발운동량에 미치는 영향에 대한 시험에서 아무런 영향을 미치지 않았다. 다만 phenobarbital sodium 수면시간에 대해서는 산초투여군에서만 다소 단축시켰다. 0.7% acetic acid의 복강내 투여에 의해 유발된 writhing syndrome을 다소 억제하였으나 유의성은 없었다. 체온에 미치는 영향에 대한 시험에서는 유의성 있는 체온 변화가 없었다. 다만 흰쥐의 위액분비에 미치는 영향에 대한 시험에서는 누룩치와 고본투여군에서 위액분비량과 총산도가 유의적으로 감소하였다. 소장운동능에 미치는 영향에 대한 시험결과 누룩치, 당귀 및 고본투여군에서 유의성 있는 charoal의 이동억제가 관찰되었다. 결론적으로 누룩치, 고본, 당귀 및 산초의 ethanol ext.는 일반약리작용에 대하여 특이한 작용이 없었다.

• 대한한방내과학회지
• /
• 제27권2호
• /
• pp.356-370
• /
• 2006

Objectives: The aim of this experimental study is to investigate effects of Dolichoris Semen, Terminaliae Fructus and Bojanggunbi-tangon the anti-cathartic action of mice and guinea pigs to develop effective herbal medicine and prescription to cure diarrhea early and to prevent side effect of chronic diarrhea. Methods: To compare effects of Dolichoris Semen, Terminaliae Fructus and Bojanggunbi-tangon the anti-cathartic action of mice and guinea pigs, we evaluated the actions on isolated gastrointestinal smooth muscles. on the transportability of small and large intestines, onthe neostigmine-induced transportability of small intestine and on diarrhea induced by castor oil, pilocarpine, barium chloride. Results: (1) Dolichoris Semen, Terminaliae Fructus and Bojanggunbi-tang showed the strong alleviation on the contraction of mice's isolated gastrointestinal smooth muscles induced by acetylcholine chloride and barium chloride. while Terminaliae Fructus, strong, Bojanggunbi-tang, intermediate and Dolichoris Semenshowed the minor alleviation on the contraction of guinea pigs' isolated gastrointestinal smooth muscles induced by acetylcholine chloride and histamine. All effects depended on the density in each medicine. (2) The tranbportability of small intestine was contrained in the groups controlled by 600 mg/kg of Dolichoris Semen, Terminaliae Fructus and Bojanggunbi-tang, and 200 mg/kg of D olichoris Semen and Terminaliae Fructus. However, the enhancement of neostigmine-induced transportability of small intestine was constrained only in the groups controlled by 600 mg/kg of Dolichoris Semen, Terminaliae Fructus and Boianggunbi-tang. (3) The transportability of large intestine was constrained by Dolichoris Semen and Bojanggunbi-tang. They showed substantial results. which depended on the amount of each medicine. (4) Terminaliae Fructus showed substantial anti-cathartic effects on diarrhea induced by caster oil in both groups controlled by 200 and 600 mg/kg of it. However, Bojanggunbi-tangshowed the effects only in the group controlled by 600 mg/kg. in diarrhea induced by pilocarpine, the groups controlled by 600 mg/kg or Terminaliae Fructus and 200 and 600 mg/kg of Boianggnbi-tangshowed substantial results. In diarrhea induced by barium chloride. the groups controlled by 200 and 600 mg/kg of Terminaliae Fructus and 600 mg/kg of Boianggunbi-tangshowed substantial results in anti-cathartic effects. Conclusions: These results show that Terminaliae Fructus is more effective on the contraction of mice and guinea pigs' isolated gastrointestinal smooth muscles, Dolichoris Semen is more effective on the transportability of small intestine, Dolichoris Semen and Bojanggunbi-tang are more effective on the transportability of large intestine. Terminaliae Fructus and Bojanggunbi-tang show substantial results in anti-cathartic actions.

• 한국콘텐츠학회논문지
• /
• 제18권5호
• /
• pp.149-155
• /
• 2018

이 연구에서는 경찰공무원의 탈진감에 따른 결근 및 징계의 정도를 살펴보았다. 독립변수인 탈진감은 선행 연구들에서 높은 신뢰도와 타당도가 검증된 Maslach Burnout Inventory(MBI)를 활용하였다. 종속변수인 결근은 결근의사, 결근실행, 거짓결근 그리고 징계는 징계경험, 징계종류로 구성하였으며, 독립변수와 종속변수 간 상관관계분석 및 회귀분석을 실시하였다. 연구 결과, 상관관계 분석에서는 탈진감과 타 요인들의 관계 중 결근 실행과 거짓 결근에서 유의미한 정적 상관관계가 나타났지만, 그 상관계수는 매우 낮았다. 또한, 탈진감과 징계 상호간에는 유의미한 상관관계가 나타나지 않았다. 회귀분석에서는 탈진감과 결근 의사, 결근 실행, 징계 종류에서 유의미한 관계가 나타났으나, 그 설명력은 매우 낮았다. 따라서 경찰공무원의 탈진감은 결근에는 전반적으로 미미한 영향을 미치지만, 징계 경험에 미치는 영향은 없음을 알 수 있다. 향후 연구에서는 이러한 관련성에 대한 보완적 조사가 이루어져야 한다.