• 제목/요약/키워드: small action

검색결과 595건 처리시간 0.03초

회음부통증 환자를 위한 Ganglion Impar의 정위적 신경절제술 -증례 보고- (Stereotaxic Neurotomy of the Ganglion Impar in the Management of Perineal Pain -A case report-)

  • 신근만;김진수;조용노;임소영;홍순용;최영룡
    • The Korean Journal of Pain
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    • 제9권2호
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    • pp.415-418
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    • 1996
  • The first reported the neural blockade of ganglion impar for pain control of perineal pain in 1990 by Plancarte and his fellows. they used 6ml of 10 percent phenol. but the point of issues, same as other neurolytics, are that it is impossible to check and control its spreading, so it might be possible to destruct the coccygeal plexus and sacral nerve, and also it has only short action time. Because of these problems, it could be very dangerous to attempt this procedure especially not for relieving the pain on cancer terminal patient, but for the sympathectomy of ganglion impar on the other purpose. We used the RF generator which had the control ability to point out the destructive lesion accurately. inserted We made the small burr hole on the sacrum near the sacrococcygeal junction directly, through the hole, and performed thermocoagulation to the ganglion impar.

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Trichoderma koningii ATCC 26113으로부터 Xylanase II의 순수분리 및 특성 (Purification and Characterization of Xylanase II from Trichoderma koningii ATCC 26113)

  • Kim, Hyun-Ju;Kang. Sa Ouk;Hah, Yung-Chil
    • 미생물학회지
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    • 제31권2호
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    • pp.157-165
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    • 1993
  • A 1, 4-.betha.-D-xylanase, designated as xylanase II, was purified from the culture filtrate of Trichoderma koningii ATCC 251131 by column chromatography on Sephadex G-75, SP-Sephadex C-50, DEAE-Sephadex A-50 and Sephadex G-50 with an overall yield of 6.97%. It has a molecular weight of 21.000 and an isoelectric point of 9.4. The enzyme activity is optimal at pH 5.0 and at a temperature of 50.deg.C. Xylanase II is stable up to 50.deg.C, while 40 and 90% of its activity are lost after the incubation for 30 and 60 min at 60.deg.C. The enzyme degrades xylan with relatively high activity, as well as carboxymethylcellulose and Avicel. Its $K_{m}$ values for oat-spelt xylan, larchwood xylan and Avicel are 7.48, 1.98 and 13.33 mg/ml, respectively. The hydrolysis products of oat-spelt xylan by xylanase II are xylose, xylobiose, xylotriose and arabinoxylotriose, while the reaction products of larchwood xylan are xylose, xylobiose, xylotriose and small amount of higher oligomers. The action paterns of the enzyme demonstrate that xylanase II is endo-enzyme.

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영화적 특성을 통한 애니메이션의 운동성 (Movement of Animation through Characteristics of Cinema)

  • 송시형
    • 한국콘텐츠학회논문지
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    • 제14권1호
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    • pp.48-55
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    • 2014
  • 서구의 근대화를 통해서 기술적 변화와 예술 사이의 새로운 관계가 형성되기 시작하였다. 그전까지 특정 개인과 소수의 사람들에 의해서 향유되던 과거의 예술이 기술에 의해 대량으로 생산됨으로써 대중적인 수용이 가능해졌다. 한 프레임씩 정지된 프레임들을 카메라로 촬영해서 재현한다는 점에서 애니메이션은 영화적 특성을 보이는데 본 연구에서는 이런 애니메이션의 영화적 운동성에 대해서 논의하면서 애니메이션에서 재현되는 운동성이 아무리 충실하게 만들어진 것일지라도 현실 세계의 운동성은 물론이고 라이브액션 영화에서 재현되는 운동성과도 동일할 수 없다는 점을 알 수 있다. 결국 애니메이션은 영화적 요소들과 애니메이션만의 디테일한 연속성으로 운동성을 창조한다. 이런 운동성으로 애니메이션만의 리얼리티가 살아나고 애니메이션이라는 예술형식의 위력을 점점 발휘시킬 수 있다.

Identification of a novel type of small molecule inhibitor against HIV-1

  • Kim, Byung Soo;Park, Jung Ae;Kim, Min-Jung;Kim, Seon Hee;Yu, Kyung Lee;You, Ji Chang
    • BMB Reports
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    • 제48권2호
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    • pp.121-126
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    • 2015
  • Here we report a new chemical inhibitor against HIV-1 with a novel structure and mode of action. The inhibitor, designated as A1836, inhibited HIV-1 replication and virus production with a 50% inhibitory concentration ($IC_{50}$) of $2.0{\mu}M$ in an MT-4 cell-based and cytopathic protection antiviral assay, while its 50% cytotoxic concentration ($CC_{50}$) was much higher than $50{\mu}M$. Examination of the effect of A1836 on in vitro HIV-1 reverse transcriptase (RT) and integrase showed that neither were molecular targets of A1836. The characterization and re-infection assay of the HIV-1 virions generated in the presence of A1836 showed that the synthesis of early RT products in the cells infected with the virions was inhibited dose-dependently, due in part to abnormal protein formation within the virions, thus resulting in an impaired infectivity. These results suggest that A1836 might be a novel candidate for the development of a new type of HIV-1 inhibitor.

발사체 탑재물 페어링 내부 공기 공급을 위한 탑재 시스템 유동 해석 (FLOW ANALYSIS OF THE ON-BOARD SYSTEM FOR THE AIR SUPPLY TO THE PAYLOAD FAIRING OF A LAUNCH VEHICLE)

  • 옥호남;김영훈;김인선
    • 한국전산유체공학회:학술대회논문집
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    • 한국전산유체공학회 2005년도 추계 학술대회논문집
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    • pp.269-273
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    • 2005
  • The on-board system for the air supply to the payload fairing(PLF) of a launch vehicle using both high and low pressure air was designed. The design concept was obtained from the CFD analysis of a Russian interstage air supply system, and a collector was adopted to expand the high pressure air. To verify that the on-board system would work as designed, a simplified axisymmetric computational model was made and a CFD analysis was also performed. It was found that the flow ejected from the hole of the collector expands to the Mach number of 4 and is soon retarded due to the action of viscosity. It was also found that a small gap between the low pressure duct and equipment bay wall can cause large velocity in PLF over the velocity requirement and no gap should be allowed in the design.

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산부인과 펄스형 $CO_2$ 레이저의 펄스모듈 특성에 의한 동작파형의 일정한 시스템의 구현 (Fixed system of action waveform by pulse module special quality of obstetrics and gynecology pulse style $CO_2$ laser relationship embodiment)

  • 김휘영
    • 대한전기학회:학술대회논문집
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    • 대한전기학회 2007년도 춘계학술대회 논문집 전기기기 및 에너지변환시스템부문
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    • pp.159-161
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    • 2007
  • $CO_2$ laser sees that is most suitable to get this effect through minimum formation damage and advantage that is root enemy of effect that happen in minimum cellular tissue depth of 0.1mm is stable living body organization or internal organs institution. Formation damage by ten can be related in formation's kind or energy density, length of evaporation time. If shorten evaporation time, surroundings cellular thermal damage 200 - because happen within 400ums laser beam in rain focus sacred ground surroundings cellular tissue without vitiation me by evaporation Poe of very small floor as is clean steam can. Application is possible to vulva cuticle cousins by a paternal aunt quantity, uterine cancer, cuticle tumor by laser system that $CO_2$ laser gets into standard in obstetrics and gynecology application. Because effect that super pulse output is ten enemies of laser if uniformity one pulse durations are short almost is decreased, most of all pulse module special quality of pulse style $CO_2$ laser for obstetrics and gynecology mode stabilization by weight very, in this research to get into short pulse duration and higher frequency density, do switching by high frequency in DC-DC Converter output DC's ripple high frequency to be changed, high frequency done current ripple amount of condenser for output filter greatly reduce can. Ripple of output approximately to Zero realization applying possible inductor realization through a special quality experiment do.

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잡곡의 품질개량 육종 성과와 전망 (Quality Breeding Outcome and Outlook in Coarse Grain Crops)

  • 최병한
    • 한국작물학회:학술대회논문집
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    • 한국작물학회 1998년도 추계 학술대회지
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    • pp.22-34
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    • 1998
  • Coarse grain crops including maize, sorghum, buckwheat, fox-tail millet, pearl millet, proso millet and barnyard millet have been used as health food, feed and industrial materials in Korea for a long time. Korean ancestors thought and treated them as the very important good crops for human health and the crops have served as a dish made with all the grains, particularly in January 15 of the lunar month in korea because the grains make the five viscera of heart, liver, spleen, lungs and kidneys and the six entrails of gall bladder, stomach, small and large intestines, the paunch, the bladder, and the bowels strong and build healthy body. Thus, the objectives of the paper were to review and summarize the results obtained from the quality breeding and functional researches worldwide on nutrition, utilization and medical action of the coarse grain crops. Maize grain, fresh ear and green fodder yields have increased since 1960s in Korea. Agronomic traits improvements also occurred for cold tolerance, disease and insect resistance, resistance to barrenness, resistance to loding, pollen production, grain and seed yields, and eating quality. For buckwheat, improved summer buckwheat varieties produced more rutin for vegetable and grain than autumn varieties in Korea

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Purification and Characterization of Two Thermostable Xylanases from Paenibacillus sp. DG-22

  • Lee, Yong-Eok;Lim, Pyung-Ok
    • Journal of Microbiology and Biotechnology
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    • 제14권5호
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    • pp.1014-1021
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    • 2004
  • Two thermostable xylanases, designated XynA and XynB, were purified to homogeneity from the culture supernatant of Paenibacillus sp. DG-22 by ion-exchange and gel-filtration chromatography. The molecular masses of xylanases A and B were 20 and 30 kDa, respectively, as determined by SDS-PAGE, and their isoelectric points were 9.1 and 8.9, respectively. Both enzymes had similar pH and temperature optima (pH 5.0-6.5 and $70^{\circ}C$), but their stability at various temperatures differed. Xylanase B was comparatively more stable than xylanase A at higher temperatures. Xylanases A and B differed in their $K_m$ and $V_{max}$ values. XynA had a $K_m$ of 2.0 mg/ml and a $V_{max}$ of 2,553 U/mg, whereas XynB had a K_m$ of 1.2 mg/ml and a $V_{max}$, of 754 U/mg. Both enzymes were endo-acting, as revealed by their hydrolysis product profiles on birchwood xylan, but showed different modes of action. Xylotriose was the major product of XynA activity, whereas XynB produced mainly xylobiose. These enzymes utilized small oligosaccharides such as xylotriose and xylotetraose as substrates, but did not hydrolyzed xylobiose. The amino terminal sequences of XynA and XynB were determined. Xylanase A showed high similarity with low molecular mass xylanases of family 11.

Rat 소장에서의 의약품(醫藥品)의 흡수(吸收)에 관(關)한 연구(硏究) 의약품(醫藥品)의 흡수(吸收)에 미치는 신미료(辛味料)의 영향(影響) (Studies on the Drug Absorption in Rat Intestine Effect on Acrid Condiments for the Absorption of Drugs)

  • 박종용;우종학;김신근;한세호
    • Journal of Pharmaceutical Investigation
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    • 제1권1호
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    • pp.3-12
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    • 1971
  • Many of the studies on absorption and excretion of drugs have been reported in the field of pharmaceutics, but the effect of acrid condiments for the absorption of drugs has not been. Hereupon, the authors investigated them in small intestine canal of rat in situ. In this experiment, aminopyrine, sulfadiazine and salicylic acid appended acrid condiments such as garlic, red pepper and pepper showed more increased absorption than constituted drugs. In particular, pepper showed the most increased than pepper, red pepper and garlic take lower absorption than pepper. When two drugs and over exist at a time, the efficacy is different from each other. Therefore, it is necessary to research of each circumstances administering one drug or compound drugs. We considers that we are abet to get safe and effectivecopound preparations when we studies on the effect. of drug action.

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조석현상이 방조제 경계면의 응력-변형 거동에 미치는 영향 분석 (The Analysis of Tidal Effect on Stress-Strain Behavior in the Boundary Surface of Sea Dike Embankment)

  • 임성훈
    • 한국농공학회논문집
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    • 제55권2호
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    • pp.1-8
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    • 2013
  • This study was performed for the purpose of analyzing the effect of tide on the stress-strain behavior in the boundary surface of sea dike embankment. Tide is a dynamic condition, but there are not suitable numerical models to solve the dynamic embankment condition caused by tide. So the analysis was simplified to quasi dynamic as follow. First, seepage by tide was analyzed according to elapsed time, and the results of the analysis at every hour during one periodic cycle time of 12 hours were applied to the pore water pressure conditions of stress-strain analysis with hyperbolic model by Duncan and Chang. The place at which maximum shear strain took place in the analysis result moved up and down repeatedly along the boundary of the dredged sand fill section and the crashed stone filter section. The value of maximum shear strain was large at high water level of tide. This result means that contraction and relaxation occur in turn repeatedly at every specific position along the boundary, and the repeated action compact loose position with sand moved down from the upper position by gravity. The experiment with the small sea dike model showed the result consistent with the numerical analysis. The surface of sea side on the dike collapsed at high water level after a couple of repetition of the rising and falling of water.