• 제어로봇시스템학회논문지
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• 제14권3호
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• pp.284-294
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• 2008

In this paper, we describe an implementation of small mobile robot that can be used at research and application of mobile sensor networking. This robot that will constitute the sensor network, as a platform of multi-robot system for each to be used as sensor node, has to satisfy restrictions in many aspects in order to perform sensing, communication protocol, and application algorithms. First, the platform must be designed with a robust structure and low power consumption since its maintenance after deployment is difficult. Second, it must have flexibility and modularity to be used effectively in any structure so that it can be used in various applications. Third, it must support the technique of wireless network for ubiquitous computing environment. At last, to let many nodes be scattered, it must be cost-effective and small. Considering the above restrictions of the mobile platform for sensor network, we designed and implemented robots control the current of actuator by using additional circuit for power efficiency. And we chose MSP430 as MCU, CC2420 as RF transceiver, and etc, that have the strength in the aspect of power. For flexibility and modularity, the platform has expansion ports. The results of experiments are described to show that this robot can act as sensor node by RF communication process with Zigbee standard protocol, execute the navigation process with simple obstacle avoidance and the moving action with RSSI(Received Signal Strength Indicator), operate at low-power, and be made with approx. $100.

• 한국정보시스템학회지:정보시스템연구
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• 제28권2호
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• pp.53-72
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• 2019

Purpose The purpose of this study is to examine the impact of tie strength in the network of industrial clustering on the knowledge acquisition, integration and innovation performance of small and medium sized enterprises. We test the positive relationship of weak tie and knowledge acquisition, strong tie and knowledge integration, and the interaction effect of two tie strengths on both processes of knowledge acquisition and integration. By identifying these relationships, we can better understand how to manage the attributes of social networks in terms of tie strength in order to improve the performance of innovation for the small and medium sized enterprises. Design/methodology/approach We collect 200 survey data from 2 industrial cluster respectively: Pankyo and Guroo. In Pankyo, the proportion of IT industry is the highest (35%) while the proportion of manufacturing is highest (35%) in Guroo. Pooling the data from two industrial cluster, we check the reliability and validity of our research model and test the hypotheses. Findings First, we find the positive relationship of weak tie and knowledge acquisition from both industrial clustering. Weak tie is composed of heterogeneous organizations with various background and expertise. The communication and information sharing of organizations in the weak tie network helps the idea generation for organization's innovation, which is the knowledge acquisition process. Second, the relationship of strong tie and knowledge integration is insignificant. Typically the strong tie from long-lasting partnership is expected to be beneficial in the action stage of innovation, which is the knowledge integration process. However it is not identified in our industry cluster. Finally, the interaction effect of weak and strong tie is identified to be effective on both knowledge acquisition and integration processes.

• 한국항공우주학회지
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• 제47권5호
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• pp.326-334
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• 2019

HILS(Hardware In the Loop Simulation)를 이용한 소형 무인항공기 개발은 비용과 시간을 줄이면서 무인항공기의 신뢰성을 높이는데 효과적으로 사용될 수 있다. 또한, 실제 비행 중에 발생할 수 있는 비행제어컴퓨터의 사용 불능상태 등을 고려한 시뮬레이션을 개발과정에 반영하면, 인명 및 재산상 피해 등의 위험을 감소시킬 수 있다. 이러한 HILS를 적용하기 위해서는 실제 비행 조건과 유사한 환경을 제공할 수 있는 실시간 시뮬레이션 환경이 요구된다. 따라서 본 논문에서는 6자유도 모션테이블을 이용하여 소형 무인항공기용 실시간 HILS 환경을 구축하였다. 선행연구에서 개발된 6자유도 모션테이블을 실시간으로 HILS 환경과 연동하기 위하여, 동작 알고리즘을 위치제어 방식에서 속도제어 방식으로 변경하여 설계 하였다. 또한, 모션테이블의 실시간 동작을 확인하기 위해 역기구학 및 동작 시뮬레이션 모델을 Matlab $Simulink^{(R)}$에서 모델링하고 검증하였다.

• Journal of Animal Science and Technology
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• 제64권4호
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• pp.752-769
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• 2022

Wheat gluten is an increasingly common ingredient in poultry diets but its impact on the small intestine in chicken is not fully understood. This study aimed to identify effects of high-gluten diets on chicken small intestines and the variation of their associated transcriptional responses by age. A total of 120 broilers (Ross Strain) were used to perform two animal experiments consisting of two gluten inclusion levels (0% or 25%) by bird's age (1 week or 4 weeks). Transcriptomics and histochemical techniques were employed to study the effect of gluten on their duodenal mucosa using randomly selected 12 broilers (3 chicks per group). A reduction in feed intake and body weight gain was found in the broilers fed a high-gluten containing diet at both ages. Histochemical photomicrographs showed a reduced villus height to crypt depth ratio in the duodenum of gluten-fed broilers at 1 week. We found mainly a significant effect on the gene expression of duodenal mucosa in gluten-fed broilers at 1 week (289 differentially expressed genes [DEGs]). Pathway analyses revealed that the significant DEGs were mainly involved in ribosome, oxidative phosphorylation, and peroxisome proliferator-activated receptor (PPAR) signaling pathways. These pathways are involved in ribosome protein biogenesis, oxidative phosphorylation and fatty acid metabolism, respectively. Our results suggest a pattern of differential gene expression in these pathways that can be linked to chronic inflammation, suppression of cell proliferation, cell cycle arrest and apoptosis. And via such a mode of action, high-gluten inclusion levels in poultry diets could lead to the observed retardation of villi development in the duodenal mucosa of young broiler chicken.

• 벤처창업연구
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• 제13권6호
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• pp.143-154
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• 2018

본 연구는 중소벤처기업의 SCM(공급사슬관리)역량과 프로세스 개선이 운영성과에 미치는 영향력을 밝히는데 목적을 갖고 중소벤처제조기업 179개사를 대상으로 실증 분석하였다. 연구결과를 보면 중소벤처기업의 SCM역량이 프로세스 개선과 운영성과에 유의한 영향을 미쳐 가설은 모두 채택되었다. 또한, 중소벤처기업의 SCM역량이 운영성과에 미치는 영향에서 프로세스개선의 매개효과 또한 유의적인 영향을 미쳐 가설4도 채택되었다. 이와 같은 결과는 중소벤처기업의 SCM역량으로서의 전략적 제휴, 기술개발, 역량집중화 요인과 프로세스 개선 요인으로서의 착수 준비, 상세 계획, 실행 관리 요인이 운영성과 요인으로서의 품질성과, 원가절감, 수익증가에 긍정적인 영향을 미치는 요인임을 실증해 주었다. 이는 중소벤처기업에서의 SCM을 도입하여 역량을 극대화시켜 프로세스를 보다 개선시키고 성과를 높이기 위해 중소벤처기업에 적합한 전략적 제휴와 기술 개발과 동시 역량집중화를 위한 선별적 투입전략이 요구됨을 의미한다. 따라서 이의 조기 적용과 정착을 위해 중소벤처기업 자체 내 업무 프로세스의 착수준비, 상세계획을 기획하여 뚜렷한 전사적 목표 관리하에 공동 실행에 옮김으로서 이들 속성에 비례한 엄격한 관리와 실행이 이어질 때 기대성과 또한 극대화 될 수 있음을 시사해준 것으로 평가할 수 있다.

• 한국식품과학회지
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• 제33권4호
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• pp.492-496
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• 2001

혈청 중성지질 저하작용을 가지고 있는 것으로 알려진 OA식 및 DEHP식을 각각 투여한 흰쥐의 간장 및 소장에서 MTP 활성과 mRNA 수준을 검토하였다. 간장 중성지질 농도는 대조군에 비교해서 OA군에서 유의하게 증가하였으나, DEHP군에서는 유의한 차이가 없었다. 혈청 중성지질 농도는 대조군에 비해서 OA군 및 DEHP군에서 유의하게 감소하였는데, 이러한 저하는 OA군에서 더욱 현저하였다. 간세포에서의 MTP 활성과 mRNA 수준은 대조군에 비해서 OA군에서 유의하게 저하하였으나, 소장에서의 MTP 활성은 증가하였다. 그러나, 간장 및 소장의 MTP 활성과 mRNA 수준은 대조군과 DEHP군 사이에서는 유의적인 변화가 없었다. 간장에 있어서 중성지질 합성의 중요 조절효소인 microsomal PAP 활성은 대조군에 비해 OA군에서 유의하게 증가하였으나, DEHP군에서는 cytosolic PAP 활성이 감소하였다. 이상의 결과로부터, OA에 의한 혈청 중성지질 저하 작용에는 간장 MTP 활성과 mRNA 유전자 발현이 깊이 관여하였으나, DEHP에 의한 혈청 중성지질 저하 작용에는 MTP 대사와는 무관한 것으로 사료되었다.

• 한국통신학회논문지
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• 제40권12호
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• pp.2491-2502
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• 2015

중소제조업 스마트공장 구현의 주요이슈는 기술개발 및 투자여력 부족에 대한 해결 방안 모색과 스마트공장 기술에 대한 정확한 구현 및 성공적 성과창출 여부이다. 제조혁신 3.0 패러다임의 실효적 추진을 위해서는 중소제조업의 가치사슬 수준에 기반을 둔 기술정책 추진의 전문성과, 글로벌 기술동향 대비 핵심기술 개발의 우선순위에 의한 세부적 실천계획이 요구된다. 이 논문은 스마트공장 구현관련 IIoT와 CPS 기술에 대한 최신 기술 및 특허 동향분석과 대응전략 및 실천과제를 제시하여 기본적 제조혁신 3.0 기획구조하의 스마트공장 구현을 지원하는데 중점을 둔다.

• Interdisciplinary Bio Central
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• 제6권1호
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• pp.1.1-1.6
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• 2014

A growing body of evidence shows that most psychological traits are polygenic, that is they involve the action of many genes with small effects. However, the study of selection has disproportionately been on one or a few genes and their associated sweep signals (rapid and large changes in frequency). If our goal is to study the evolution of psychological variables, such as intelligence, we need a model that explains the evolution of phenotypes governed by many common genetic variants. This study illustrates simple statistical tools to detect signals of recent polygenic selection: a) ANOVA can be used to reveal significant deviation from random distribution of allele frequencies across racial groups. b) Principal component analysis can be used as a tool for finding a factor that represents the strength of recent selection on a phenotype and the underlying genetic variation. c) Method of correlated vectors: the correlation between genetic frequencies and the average phenotypes of different populations is computed; then, the resulting correlation coefficients are correlated with the corresponding alleles' genome-wide significance. This provides a measure of how selection acted on genes with higher signal to noise ratio. Another related test is that alleles with large frequency differences between populations should have a higher genome-wide significance value than alleles with small frequency differences. This paper fruitfully employs these tools and shows that common genetic variants exhibit subtle frequency shifts and that these shifts predict phenotypic differences across populations.

• 동의생리병리학회지
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• 제27권1호
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• pp.112-117
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• 2013

We studied the modulation of pacemaker activities by Samchulkunbi-tang (SCKB) in cultured interstitial cells of Cajal (ICC) from murine small intestine with the whole-cell patch-clamp technique. Externally applied SCKB produced membrane depolarization in the current-clamp mode. The pretreatment with $Ca^{2+}$-free solution and thapsigargin, a $Ca^{2+}$-ATPase inhibitor in endoplasmic reticulum, abolished the generation of pacemaker potentials and suppressed the SCKB-induced action. The application of flufenamic acid (a nonselective cation channel blocker) abolished the generation of pacemaker potentials by SCKB. However, the application of niflumic acid (a chloride channel blocker) did not inhibit the generation of pacemaker potentials by SCKB. In addition, the membrane depolarizations were inhibited by not only GDP-${\beta}$-S, which permanently binds G-binding proteins, but also U-73122, an active phospholipase C inhibitor. These results suggest that SCKB modulates the pacemaker activities by nonselective cation channels and external $Ca^{2+}$ influx and internal $Ca^{2+}$ release via G-protein and phospholipase C-dependent mechanism. Therefore, the ICC are targets for SCKB and their interaction can affect intestinal motility.

• 한국운동역학회지
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• 제13권3호
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• pp.311-325
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• 2003

A relation between the movement range of arms and arising moment has been studied to find out efficient movement range to minimize impact concerning arm landing in sports aerobics. Four male athletes who won top three in national-level sports aerobics competition were chosen for the experiment. They were allowed to jump in between two force platform so that the right hand and the right leg could land onto the front and rear force platform, respectively. The sampling frequency was 200 Hz. The main conclusions based on the analysis of the angle and joint moment parameters of wrist, elbow, and shoulder are as follows: 1. The wrist moment was small when its angle was small, indicating that the dorsi-flexion of the wrist joint offered a positive influence to reduce wrist moment. 2. The elbow angle increased as wrist angle decreased and vice versa. This means that the movement range of the wrist joint affects that of the elbow joint. The darsi-flexion of the wrist is the position to absorb the impact of the elbow effectively rather than to absorb the impact of the wrist itself. The impact is absorbed by the flexion of wrist joint rather than the wrist. 3. The degree of moment transfer of the shoulder joint, having absorbed the impact from the elbow and elbow joint, became dependent on the efficiency of the fore-joints impact absorption.