• Title/Summary/Keyword: slow phase

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CORRELATIONS BETWEEN HIPPOCAMPAL THETA RHYTHM AND INTRACELLULAR CHARACTERISTICS OF PYRAMIDAL NEURONS (해마 theta 리듬과 pyramidal neuron의 세포내 특성과의 상관관계)

  • Kwon, Oh-Heung;Kim, Young-Jin;Nam, Soon-Hyeun;Kim, Hyeun-Jung;Lee, Man-Gee;Cho, Jin-Hwa;Choi, Byung-Ju
    • Journal of the korean academy of Pediatric Dentistry
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    • v.25 no.4
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    • pp.671-682
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    • 1998
  • Electrophysiological phenomena of pyramidal cells in the CA1 area of the dorsal hippocampus were recorded from and filled with neurobiotin in anesthetized rats. The electropharmacological properties of membrane as well as the cellular-synaptic generation of rhythmic slow activity (theta) were examined. The intracellular response characteristics of these pyramidal cells were distinctly different from responses of interneurons. Pyramidal cells had a high resting membrane potential, a low input resistance, and a large amplitude action potential. A afterhyperpolarization was followed a single action potential. Most of pyramidal cells did not display a spontaneous firing. Pyramidal cells displayed weak inward rectification and anodal break excitation. The slope of the frequency-current relation was 53.4 Hz/nA for the first interspike interval and 15.9 Hz/nA for the last intervals, suggesting the presence of spike frequency adaptation. Neurobiotin-filled neurons showed pyramidal morphology. Cells were generally bipolar dendritc processes ramifying in stratum lacunosum-moleculare, radiatum, and oriens. Commissural stimulation discharged pyramidal cells, followed by excitatory and inhibitory postsynaptic potentials (EPSPs and IPSPs). The frequency of theta-related membrane potential oscillation was voltage-independent in pyramidal neurons. At strong depolarization levels (less than 30 mV) pyramidal cells emitted sodium spike oscillation, phase-locked to theta. The observations provide direct evidence that theta-related rhythmic hyperpolarization of principal cells is brought by the rhythmically discharging interneurons. Furthermore, the findings in which interneurons were also paced by rhythmic inhibitory postsynaptic potentials during theta suggest that they were periodically hyperpolarized by their GABAergic septal afferents.

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INTENSITY AND DOPPLER VELOCITY OSCILLATIONS IN PORE ATMOSPHERE

  • Cho, Kyung-Suk;Bong, Su-Chan;Nakariakov, Valery;Lim, Eun-Kyung;Park, Young-Deuk;Chae, Jongchul;Yang, Heesu;Park, Hyung-Min;Yurchyshyn, Vasyl
    • The Bulletin of The Korean Astronomical Society
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    • v.39 no.2
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    • pp.98-98
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    • 2014
  • Due to the simple vertical structure of magnetic field, pores can be exploited to study the transport of mechanical energy by waves along the magnetic field to the chromosphere and corona. For a better understanding of physics of pores, we have investigated chromospheric traveling features running across two merged pores from their centers at the speed about 55 km s-1, in the active region AR 11828. The pores were observed on 2013 August 24 by using high time, spatial, and spectral resolution data from the Fast Imaging Solar Spectrograph (FISS) of the 1.6 meter New Solar Telescope (NST). We infer a LOS velocity by applying the bisector method to the Ca II $8542{\AA}$ band and $H{\alpha}$ band, and investigate intensity and the line-of-sight velocity changes at different wavelengths and different positions at the pores. We find that they have 3 minutes oscillations, and the intensity oscillation from the line center is preceded by that from the core ($-0.3{\AA}$) of the bands. There is no phase difference between the intensity and the LOS velocity oscillations at a given wavelength. The amplitude of LOS velocity from near the core spectra is greater than that from the far core spectra. These results support the interpretation of the observed wave as a slow magnetoacoustic wave propagating along the magnetic field lines in the pores. The apparent horizontal motion and a sudden decrease of its speed beyond the pores can be explained by the projection effect caused by inclination of the magnetic field with a canopy.

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A Study on the Realization of Broadband frequency Multiple VCO for Multi-Band Radar Detector (다중 대역 레이더 탐지기용 광대역 주파수 체배 VCO 구현에 관한 연구)

  • Park Wook-Ki;Kang Suk-Youb;Go Min-Ho;Park Hyo-Dal
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.30 no.10A
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    • pp.971-978
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    • 2005
  • In this paper, we design and fabricate a VCO(Voltage Controlled Oscillator) for radar detector of X/K/Ka band using frequency multiplier. The existing VCO operated in radar detector have many Problems such as narrow bandwidth, slow frequency variable rate, unstable of production due to high frequency. So we design and fabricate a VCO improved such problems using frequency multiplier. As a result of measure, investigated frequency multiple VCO show its output power 3.64 dBm at multiplied operating frequency 11.27 GHz and have wide frequency tuning range of 660 MHz by controlled voltage 0V to 4.50 V applied diode. And also its phase noise is -104.0 dEc at 1 MHz offset frequency so we obtain suitable performance for commercial use.

An Experimental Study on Flow Characteristics of Turbulent Pulsating Flow in a Curved Duct by using LDV (LDV에 의한 곡관덕트에서 난류맥동유동의 유동특성에 관한 실험적 연구)

  • Lee, Hong-Gu;Son, Hyun-Chul;Lee, Haeng-Nam;Park, Gil-Moon
    • Proceedings of the KSME Conference
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    • 2000.11b
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    • pp.397-403
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    • 2000
  • In the present study, flow characteristics of turbulent pulsating flow in a square-sectional $180^{\circ}$ curved duct were experimentally investigated. Experimental studies for air flows were conducted to measure axial velocity and wall shear stress distributions and entrance length in a square-sectional $180^{\circ}$ curved duct by using the LDV with the data acquisition and the processing system. The experiment was conducted in seven sections from the inlet (${\phi}=0^{\circ}$) to the outlet (${\phi}=180^{\circ}$) at $30^{\circ}$ intervals of the duct. The results obtained from the experimentation were summarized as follows ; (1) When the ratio of velocity amplitude ($A_1$) was less than one, there was hardly any velocity change in the section except near the wall and any change in axial velocity distributions along the phase. When the ratio of velocity amplitude ($A_1$) was 0.6, the change rate of velocity was slow. (2) Wall shear stress distributions of turbulent pulsating flow were similar to those of turbulent steady flow. The value of the wall shear stress became minimum in the inner wall aid gradually increased toward the outer wall where it became maximum. (3) The entrance length of turbulent pulsating flow reached near the region of bend angle of $90^{\circ}$, like that of turbulent steady flow. The entrance length was changed by the dimensionless angular frequency (${\omega}^+$).

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Defecation of Norovirus from the Oyster Crassostrea gigas by Depuration Following Translocation of the Growing Area (자연정화에 의한 양식굴(Crassostrea gigas) 중 노로바이러스 저감화)

  • Yu, Hongsik;Park, Yong Su;An, Sera;Park, Kunbawui;Shim, Kil Bo;Song, Ki Cheol;Lee, Tae Seek
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.49 no.2
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    • pp.109-115
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    • 2016
  • The efficacy of depuration following growing area translocation for the defecation of norovirus was evaluated under experimental conditions using oysters Crassostrea gigas previously subjected to bioaccumulation of this virus at a waste treatment plant discharge site. Three trials were assayed in an open experimental system with a commercial oyster farm located in a shellfish growing area approved by the Korean Shellfish Sanitation Program. Real-time reverse-transcription polymerase chain reaction (RT-PCR) was used to quantify viruses in the digestive glands of oysters. The final viral loads in oysters after 12 days remained under the detection limit (10 copies/g digestive gland) of the real-time RT-PCR. This reduction trend showed two-phase removal kinetics, with an initial slow reduction or slight increase in viruses during the first 2 days of depuration and subsequent stabilization with 0.12 to 2.64 log unit norovirus copies/g digestive gland per 2 days of depuration for the remaining time.

Hydrolysis by Alcalase Improves Hypoallergenic Properties of Goat Milk Protein

  • Jung, Tae-Hwan;Yun, Sung-Seob;Lee, Won-Jae;Kim, Jin-Wook;Ha, Ho-Kyung;Yoo, Michelle;Hwang, Hyo-Jeong;Jeon, Woo-Min;Han, Kyoung-Sik
    • Food Science of Animal Resources
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    • v.36 no.4
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    • pp.516-522
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    • 2016
  • Goat milk is highly nutritious and is consumed in many countries, but the development of functional foods from goat milk has been slow compared to that for other types of milk. The aim of this study was to develop a goat milk protein hydrolysate (GMPH) with enhanced digestibility and better hypoallergenic properties in comparison with other protein sources such as ovalbumin and soy protein. Goat milk protein was digested with four commercial food-grade proteases (separately) under various conditions to achieve the best hydrolysis of αs -casein and β-lactoglobulin. It was shown that treatment with alcalase (0.4%, 60℃ for 30 min) effectively degraded these two proteins, as determined by SDS-PAGE, measurement of nonprotein nitrogen content, and reverse-phase high-performance liquid chromatography. Hydrolysis with alcalase resulted in a significant decrease in β-lactoglobulin concentration (almost to nil) and a ~40% reduction in the level of αs-casein. Quantification of histamine and TNF-α released from HMC-1 cells (human mast cell line) showed that the GMPH did not induce an allergic response when compared to the control. Hence, the GMPH may be useful for development of novel foods for infants, the elderly, and convalescent patients, to replace cow milk.

A Performance Analysis of AM-SCS-MMA Adaptive Equalization Algorithm based on the Minimum Disturbance Technique (Minimum Disturbance 기법을 적용한 AM-SCS-MMA 적응 등화 알고리즘의 성능 해석)

  • Lim, Seung-Gag
    • The Journal of the Institute of Internet, Broadcasting and Communication
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    • v.16 no.3
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    • pp.81-87
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    • 2016
  • This paper analysis the AM-SCS-MMA (Adaptive Modulus-Soft Constraint Satisfaction-MMA) based on the adaptive modulus and minimus-disturbance technique in order to improve the stability and robustness in low signal to noise power of current MMA adaptive equalization algorithm. In AM-SCS-MMA, it updates the filter coefficient applying the adaptive modulus and minimum-disturbance technique of deterministic optimization problem instead of LMS or gradient descend algorithm for obtain the minimize the cost function of adaptive equalization. It is possible to improve the equalizer filter stability, robustness to the various noise characteristic and simultaneous reducing the intersymbol interference due to the amplitude and phase distortion occurred at channel. The computer simulation were performed for confirming the improved performance of SCS-MMA. For these, the output signal constellation of equalizer, residual isi, MSE, EMSE (Excess MSE) which means the channel traking capability and SER which means the robustness were applied. As a result of computer simulation, the AM-SCS-MMA have slow convergence time and less residual quantities after steady state, more good robustness in the poor signal to noise ratio, but poor in channel tracking capabilities was confirmed than MMA.

Characterization of thermally driven polysilicon micro actuator (폴리실리콘 마이크로 액츄에이터의 열구동 특성분석)

  • Lee, Chang-Seung;Lee, Jae-Youl;Chung, Hoi-Hwan;Lee, Jong-Hyun;Yoo, Hyung-Joun
    • Proceedings of the KIEE Conference
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    • 1996.07c
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    • pp.2004-2006
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    • 1996
  • A thermally driven polysilicon micro actuator has been fabricated using surface micromachining techniques. It consists of P-doped polysilicon as a structural layer and TEOS (tetracthylorthosilicate) as a sacrificial layer. The polysilicon was annealed for the relaxation of residual stress which is the main cause to its deformation such as bending and buckling. And the newly developed HF VPE (vapor phase etching) process was also used as an effective release method for the elimination of sacrificial TEOS layer. The thickneas of polysilicon is $2{\mu}m$ and the lengths of active and passive polysilicon cantilevers are $500{\mu}m$ and $260{\mu}m$, respectively. The actuation is incurred by die thermal expansion due to the current flow in the active polysilicon cantilever, which motion is amplified by lever mechanism. The moving distance of polysilicon micro actuator was experimentally conformed as large as $21{\mu}m$ at the input voltage level of 10V and 50Hz square wave. The actuating characteristics are investigated by simulating the phenomena of heat transfer and thermal expansion in the polysilicon layer. The displacement of actuator is analyzed to be proportional to the square of input voltage. These micro actuator technology can be utilized for the fabrication of MEMS (microelectromechanical system) such as micro relay, which requires large displacement or contact force but relatively slow response.

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The Changes of Sleep-Wake Cycle from Jet-Lag by Age (연령에 따른 비행시차 후의 수면-각성주기 변화)

  • Kim, Leen;Lee, Seung-Hwan;Suh, Kwang-Yoon
    • Sleep Medicine and Psychophysiology
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    • v.3 no.2
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    • pp.18-31
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    • 1996
  • Jet-lag can be defined as the cumulative physiological and psychological effects of rapid air travel across multiple time zones. Many reports have suggested that age-related changes in sleep reflect fundamental changes in the circadian system and in significant declines in slow wave sleep. Jet lag is a dramatic situation in which the changes of the phase of circadian process and homeostatic process of sleep occur. Thus the authors evaluatead the changes of sleep-wake cycle from jet lag by age. Thirty-eight healthy travellers were studied for 3 days before and 7 days after jet-flights across seven to ten time zone. They were aged 19-70, They trareled eastbound, Seoul to North America (USA, Canada). Sleep onset time, wake-up time, sleep latency, awakening frequency on night sleep, awakening duration on night sleep, sleepiness at wake-up and nap length were evaluated. Our results suggest that by the 7 to 10 time zone shift, the old age group was significantly influenced in sleep-wake cycles. The date on which subjective physical condition was recovered was $6.23{\pm}83$ day after arrivals for old age group, while for young and middle age group, $4.46{\pm}1.50$ day and $4.83{\pm}1.52$ day, respectively. In old age group, sleep onset time was later than baselines and could not recover untill 7th day. But in other groups, the recovery was within 5th day. Nap dura fion was longer in old age group through jet lag than younger age group. In other parameters, there was no definite difference among three age groups. Our results suggested that the old age was significantly influenced by the disharmony between internal body clock and sleep-wake cycle needed at the travel site. Thus we proved that recovery ability from jet lag was age-dependent as well as travelling direction-dependent. To demonstrate more definite evidence, EEG monitoring and staging of sleep were funthun encouraged.

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The Effects of the Microstructures on the Fatigue Crack Propagation Behaviors of Cast Irons (주철의 피로전파거동에 미치는 미세조직의 영향)

  • Kim, Sug-Won;Park, Jin-Sung;Lee, Hyung-Chul;Kim, Dong-Keun;Woo, Kee-Do
    • Journal of Korea Foundry Society
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    • v.25 no.1
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    • pp.16-22
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    • 2005
  • This study aims to investigate the effects of the microstructures and nodule type on the fatigue characteristics of cast iron. Fatigue tests were carried out in tension-tension mode using a servo-hydraulic testing machine with load control mode operating at a frequency of 15 Hz. The tests were conducted at stress ratio R=Kmin/Kmax, of 0.1. Initial crack ${\Dalta}K$ values were highly performed with increase in tensile strength of DCI fatigue specimens. ${\Dalta}K_{th}$ region, fatigue crack propagation was primarily advanced through cell boundary and in periphery of near nodule. Fatigue crack propagation rate of D2 consisted with 2Phase(Ferrite+Pearlite) was slow due to crack closure enhanced by crack deflection and occurred crack branching. The generation of crack branch was occurred due to interaction of crack-nodule. At Threshold and Paris zone, the fractographs of the fatigue fracture surface for DCI show typical striations of a ductile fracture and isolated cleavage planes near graphite. The effect of microstructure on fatigue crack propagation of GC strongly depends on the type of flake. The generation of crack branch occurred due to interaction of crack-nodule. The fractographs of the fatigue fracture surface for GC show cleavage plane along the flake graphite.