• Design & Manufacturing
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• v.11 no.1
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• pp.1-6
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• 2017

In these days, due to generalization of using smart mobile phone and wearable device such as smart watch, demand of Cover-glass and touch screen panel for protecting display increases. With increasing the demand of Cover-glass, slimming technique is promising for weight lightening, zero bezel. Cover-glass produced by this technique is required to decreasing thickness with increase strength. In the Cover-glass manufacturing process, mechanical processing and chemical processing has improve in the strength. Generally, Diamond electrodeposition wheel is used in mechanical process. Reinforced glass with the characteristics of the brittle and high hardness was manufactured by using a diamond electrodeposition wheel. At this time, Because of surface of the tool present non-uniform distribution of diamond particle, it has generate Loading of wheel and it has been decrease life of grinding tool, efficiency of grinding, quality and shape accuracy of workpiece. Thus Research is needed to controling particle distribution of diamond electrodeposition wheel uniformly. And it is necessary to study micro hole machining such as proximity senser hole, speaker hole positioned Cover-glass. Reinforced glass with the characteristics of the brittle and high hardness is difficult to machining. Processing of reinforced glass have generated wear of tool, micro cracks. Also, it is decreasing shape accuracy. In this paper, We conducted a study on how to control particle distribution uniformly about the diamond tool manufactured using elecetodeposition processing. It analyzed the factors that affect the arrangement of the particles in the electrodeposition process by design of experiment. And There is produced the grinding tool, which derives an optimum deposition conditions, for processing Cover-glass edge and the machinability was evaluated.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.14 no.10
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• pp.4713-4718
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• 2013

Nowadays, three-dimensional computer added design(3D CAD) tool are widely and actively used for design of mechanical machine. Because using the tool is more effective to understand design concept and to collaborate with other operation than using two-dimensional design tool. In this study, the 3D CAD tool which is called I-DEAS was applied for three-dimensional modeling of main parts and assembling of modeled parts for identification the entire shape of a injection molding machine. In addition, a study was also performed regarding reduction for the weight of main plates for saving production cost and energy in the machine. A finite element method(FEM) program in I-DEAS tool was used for the improvement study. First, the current main plates were structural analysed and then the plate deformations, weak regions and stress distributions were graped. By the FEM results, the 2nd improved designing of the plates was conducted such as reinforcement or slimming of the plate wall thickness. The 2nd structural FEM was performed for verification of the redesigned plates and then the FEM results were compared with the 1st FEM's result. The weight of the main plates were averagely reduced approximately 3 - 7%. By these results, it was seemed that the improved plates have a useful availability.

• Proceedings of the Korean Society of Embryo Transfer Conference
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• 2002.11a
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• pp.110-110
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• 2002

Rapidly progressive interstitial renal fibrosis has recently been reported in young women who have been on a slimming regimen including chinese herbs. Aristolochic acid, suspected as the causal factor of this renal disease, is a well known carcinogen. It has been known that Madouling (Aristolochiae fructus) contains aristolochic acid. The objective of this study was to investigate the effects of Madouling, Madouling-tang, which are the extract mixture from 10 different chinese herbs including Madouling, and aristolochic acid on reproductive and developmental toxicity. Female rats were administered orally with the extracts of Madouling, madouling-tang, and aristolochic acid from 14 days before mating to day 17 of gestation. Madouling (8mg/kg) decreased fertility in the 8mg/kg group, but Madouling-tang and aristolochic acids did not. Significant decrease of mean fetal body weights were observed in the 16mg/kg group of aristolochic acids. External, visceral and skeletal malformation of fetuses were not observed with treatment. Histopathological examination showed the discrete damage of kidney in the 8mg/kg group of Madouling and 16mg/kg groups of aristolochic acid. In whole embryo culture, Madouling and Madouling-tang caused the retardation of growth and development of embryo in the dose of 1 $\mu$g/ml and 0.02 $\mu\textrm{g}$/kg, respectively while aristolochic acids showed the similar effect in the dose of 300 $\mu\textrm{g}$/kg. These results indicate that Madouling, up to 0.05mg/kg (prescription dose to human) has no adverse effects on the fertility, reproduction and development of Sprague-Dawley rats.

• Proceedings of the SCSK Conference
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• 2003.09b
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• pp.87-107
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• 2003

It was demonstrated that Transactivating transcriptional activator(TAT) protein from HIV-1 shown to enter cells when added to the surrounding media. TAT peptide chemically attached to various proteins was able to deliver these proteins to various cell and even in tissues in mice with high levels in heart and spleen. In this study, the tripeptide GKH(Glycine-Lysine-Histidine) derived from Parathyroid hormone (PTH), which was known as lipolytic peptide, is attached to 9-poly Lysine(TAT) to be used as a cosmetic ingredient for slimming products. When Glycerol release, expressed as extracellular glycerol concentration, is lipolysis index, TAT-GKH at $10^{-5}$mo1/L induces approximately 41.5% maximal lipolytic effects in epididymal adipocytes isolated from rats, compared with basal lipolysis. Epididymal adipose tissues of male rats is assessed ex vivo by microdialysis. Probes are perfused with Ringer solution in which increasing concentrations of TAT-GKH. The perfusion of TAT-GKH induces lipolytic effect. Penetration study showed that TAT-GKH efficiently elevates 36 times higher penetration into the excised hairless mice skin than GKH. in vivo study showed that TAT-GKH had a better effect upon the relative volume of eye bag after 28 days of application on twenty(+2) healthy female volunteers. It was identified that TAT-GKH increases penetration enhancement and lipolytic effects in both in vitro, ex vivo and in vivo.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.35 no.2
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• pp.111-116
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• 2009

Gymnema sylvestre, a traditional India medicine called a 'Gagaimogouip' in Korea, has been used to regulate sugar metabolism in patients with diabetes mellitus. First, we induced callus from Gymnema sylvestre leaf and mode extract from cultured callus. In this study, we investigated the anti-obesity effect of tissue-cultured Gymnema sylvestre leaf extract in 3T3-L1 cells. The tissue-cultured Gymnema sylvestre extract inhibited the cytoplasmic lipid accumulation as well as adipogenic differentiation of preadipocytes. The tissue-cultured Gymnema sylvestre extract inhibited insulin-induced predipocyte differentiation through the inhibition of expression of the early adipogenic transcription factor C/EBP-${\alpha}$ that regulate adipogenesis. These results indicate that tissue-cultured Gymnema sylvestre extract may be potential natural ingredient for slimming cosmetic products.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.36 no.2
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• pp.145-150
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• 2010

Anoectochilus formosanus, commonly known as "Jewel Orchids", which has been used in traditional folk medicines for feber, pain, and diseases of the lung and liver in Taiwan. We artificially cultured Anoectochilus formosanus plantlet by using the bioreactor culture system for this study from Anoectochilus formosanus. Previously, several studies have been reported on pharmacological activities of lipid-metabolism, hepatoprotective activity, anti-tumor activity and immuno-stimulating effects but other efficacy were not well known as a cosmetic ingredient for skin care. In this study, we investigated the effect of melanogenesis in B16 mouse melanoma cells and lipid droplet accumulation in 3T3-L1 preadipocytes about Anoectochilus formosanus plantlet extract. We report that Anoectochilus formosanus plantlet extract inhibits the cytoplasmic lipid droplet accumulation through adipogenic differentiation of preadipocytes as well as inhibition of tyorsinase activity and melanogenesis. As a result, our findings indicate that Anoectochilus formosanus plantlet extract may be the potential natural ingredient for whitening and slimming cosmetic products.

• Journal of the Korea society of information convergence
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• v.8 no.1
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• pp.13-23
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• 2015

The study examines the current situations of bank industry whose profitability has been worse recently, finds out the causes of the reduced bank profits, and presents ways to solve the problem. The ways to strengthen the profitability are as follows:First, the expansion of business area is needed. It is necessary to expand business that will create new profits through M&A between the bank and other industries. Second, reorganization for the high-value business is needed. The bank should no longer depend on the profits by deposits and loans, but develop high-value business area for high profitability. The bank business strategy needs to focus on the long-term profitability, not the short-term one. Third, the structure of bank needs to be slimmed. Slimming the structure should be based on the efficiency of business for the future, not for a short-sighted profitability. Fourth, the interest rates of deposits and loans need to be differentiated. The bank profitability can be enhanced by promoting deposits and loans which reflect low risk and high profitability. Fifth and lastly, advancing to abroad needs to be revitalized. Securing the oversea's bank markets can play a key role in strengthening the profitability of banks in the future.

• Korean Journal of Psychosomatic Medicine
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• v.9 no.2
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• pp.153-163
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• 2001

This study was attempted to investigate the discriminant validity of Korean version of Eating Attitude Test-26(KEAT-26) and to provide the sensitivity, specificity and efficiency according to cutting score, which may be useful to determine the optimal cutoff point on various purposes. The KEAT-26 was administered to 108 female patients with eating disorders, 179 female participants in body slimming center, 120 female athletic college students, 227 female college students, and 183 healthy normal women. Validity was tested by ANOVA and ROC curve analysis. The results revealed that the total score of the KEAT-26 showed a statistically significance between groups and that the score of the KEAT-26 of eating disorders group was significantly higher than that of the other groups in post hoc test. In comparison of the 4 subfactor score of the KEAT-26 between groups, significant differences in main effect within groups were found in all subfactors except factor IV. ROC curve analysis showed 80% of efficiency to discriminate eating disorders group from normal control group using cutoff score on maximum discriminant efficiency and 69% of efficiency to discriminate eating disorders group from high risk groups for eating disorders. Each cutoff score on maximum in efficiency was as follows ; 25 between eating disorders group and participants in body slimming center, 19 between eating disorders group and healthy normal woman, 23 between eating disorders group and athletic college students, 21 between eating disorders group and college students. Using 22(T score 65) of the KEAT-26 as the cutoff score, sensitivity was 54%, specificity was 84%, and overall efficiency was 80%. These results indicate that the KEAT-26 has a good discriminant validity in Korean population and also suggest that the KEAT-26 may be useful assessment tool to screen the disordered eating problems on clinical and epidemiological purposes.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.6
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• pp.37-45
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• 2018

An electric vehicle is an environmentally friendly vehicle because there is no exhaust gas, unlike gasoline automobiles. On the other hand, because the electric vehicle is driven by electric power charged in batteries, the distance to go through a single charge depends on the energy density of the batteries. Therefore, a lithium-ion battery with a high energy density is a good candidate for batteries in electric vehicles. Because the electrode is an essential component that governs the efficiency of a lithium-ion battery, the electrode manufacturing process plays a vital role in the entire production process of lithium-ion batteries. In particular, the drying process during the electrode manufacturing process is a critical process that has a significant influence on the performance. This paper proposes an innovative process for improving the efficiency and productivity of the drying process in electrode manufacturing and describe the equipment design method and development results. In particular, the design procedure and development method for enhancing the electrode adhesion power, atmospheric pressure superheated steam drying technology, and drying furnace slimming technologies are presented. As a result, high-speed drying technology was developed for battery electrodes through the world's first turbo dryer technology for mass production using open/integrated atmospheric pressure superheated steam. Compared to the conventional drying process, the drying furnace improved the productivity (Dry Lead Time $0.7min{\rightarrow}0.5min$).

• Journal of the Korea Academia-Industrial cooperation Society
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• v.16 no.2
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• pp.927-939
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• 2015

It appears that the rapid advance in technology has allowed to broaden the variety of rail systems technology, thereby fostering new business opportunity in rail industry. The direction of rail systems operations is mainly two fold. In one direction, long distance operations between mega cities are pursued with help of high speed trains under development. In the other case, relatively short distance operations for covering intra-city or suburban area are becoming popular. A good example of the latter case is light rail transit (LRT) systems. Due to the short distance operation, it is thus expected that both the development and operation cost for LRT systems be reduced to some extent. The cost reduction desired in there can be gained by scaling down the sizes of both the trains and stations as compared to those of normal rail systems. However, it is not well known how the LRT stations can be scaled down. The objective of this paper is to study on how to slim down the stations (particularly, the functions room) of LRT systems. To achieve the objective, an approach is studied based on a modified method of design structure matrix (DSM). Specifically, using the enhanced DSM method, an integrated architecture is developed for the functions room, in which equipments are housed to perform the functions of electricity, signaling, and communication for LRT stations. The use of the result indicates that the desired reduction can be obtained with the approach taken in the paper.