• 보건의료산업학회지
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• 제11권4호
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• pp.169-178
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• 2017

Objectives : In this study, we investigated the correlation of mental-and oral-health status with periodontal disease. Ultimately, we sought to make a positive contribution to the promotion of periodontal health and the prevention of periodontal disease. Methods : This study was analyzed using the data of KNHANES 2013-2015. The participants of this study were between 20 and 64 years old. The final selection was 1,512 adults. Results : Participants with a sleeping time of less than 6 hours and those who recognized stress showed higher periodontal disease. Number of decaying teeth, oral-health status, toothaches, and chewing problems were associated significantly with periodontal disease. To investigate the effects of general characteristics and mental and oral-health status on periodontal disease, a logistic regression analysis was conducted. Sex, age, education level, smoking status, oral-health status, and chewing problems were variables that affected periodontal disease. Conclusions : This study showed that mental-and oral-health status is closely related to periodontal disease. Therefore, it is expected that this will be used as basic data to effectively improve periodontal disease in adults.

• 가정과삶의질연구
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• 제30권4호
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• pp.119-132
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• 2012

The purpose of this study was to investigate the differences in time use between Korean and American high school students. The data sources were the '2009 Time Use Survey' conducted by Korea National Statistical Office and the '2009 ATUS (American Time Use Survey)' conducted by Labor Statistics Division in the U.S.. 1,734 Korean diaries (1,311 on weekdays and 423 on Sundays) and 321 American diaries (208 on weekdays and 113 on Sundays) from high school students of 15 to 18 years of age were analyzed. Descriptive statistics and t-test were used for the statistical analysis. The time use patterns of Korean students on weekdays and Sundays were different than those of their American counterparts. On weekdays and Sundays, the sleeping time of Korean students was 2 hours less than the time of their American counterparts. Koreans studied more, nearly double the time of their American counterparts on weekdays and five times more on Sundays. The study-oriented time allocation of Korean students resulted in less leisure time than the American students. Korean students spent their leisure time of more than 30 minutes participating in social activities, media, and hobbies, and their time allocation to volunteer work and religious activities were nil. On Sundays, the time for studying by Korean students was more than five times longer than that spending by their American counterparts. Koreans used their leisure time of 6 hours and 47 minutes mainly for media, hobbies and social activities. The participation rate of volunteering by Korean students was only 0.5%, though it was 31.0% for the Americans. For a study-life balance for Korean students, it was recommended that trends toward time management and social policy should increase the time allocation to sleeping, housework, work, sports, and volunteering and decrease the time use in studying and hobbies.

• 한국지역사회생활과학회지
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• 제21권3호
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• pp.365-377
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• 2010

This study examined the changes in sleeping and studying patterns of young students and their mothers after moving to foreign countries. This study analyzed the relational characteristics of Geese Family members which are summarized as follows: 1) Sleeping Pattern: At the early stages of settling into foreign countries, students begin to sleep in the same bedroom with their mothers, who had used to sleep in separate bedrooms back in Korea. This change in pattern may slightly vary according to the age and gender of the students, and type of residence. Relationships between young students and mothers become more tightly coupled. However, relationships between students and fathers become less tightened. 2) Studying Pattern: Students tend to study in the public space such as the living room and dining areas, rather than in their own private rooms. This is because mothers want to support and focus upon their children's study by sacrificing normal family activities. These patterns appear stronger as their period of study in the foreign country becomes shorter and the ages of the students become younger. These studying patterns also contribute to the coupling between mothers and young students. 3) Family Relationships: From the period as Geese Families, the relation between mothers and young students become closer both physically and emotionally. The relation between fathers and children become less close. The role of fathers is degraded to that of supporter or negotiator for the time period of the mothers and child students in the foreign country.

• 한국정보통신학회:학술대회논문집
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• 한국정보통신학회 2021년도 춘계학술대회
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• pp.425-427
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• 2021

현대 사회에 들어서면서 사회생활과 더불어 일상생활의 변화로 인해 현대인들이 가지는 수면 부족과 불만족스러운 수면 환경으로 전 세계에서 수면 부족국가 최하위, 수면 부족이라고 생각되는 국가 최하위를 기록하고 있다. 수면 부족을 이끄는 원인 중 2위를 차지하는 '수면 환경'을 개선할 수 있는 '아두이노를 활용한 수면 베개'에 대한 내용이다. 수면에 들기 전 몇 분 그 잠시의 시간이 수면의 질을 좌우할 수 있으며, 수면의 질은 하루 생활의 만족감을 결정한다. 아두이노를 활용하여 다양한 기능을 통해 수면의 질을 높일 수 있다. 아두이노를 통해 수면자의 호흡 측정, 조명, 블루투스 스피커를 조절하여 수면자의 수면 환경을 조성하고 자신에게 맞는 환경을 직접 만들 수 있다. 이를 통해 현대인의 수면 부족을 개선하고 더 윤택한 삶을 가질 수 있을 것이다.

• Natural Product Sciences
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• 제22권4호
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• pp.263-269
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• 2016

Rhynchophylline (RP) is a major tetracyclic oxindole alkaloid of Uncariae Ramulus et Uncus which has been used to treat hypertension, seizures, pain and anxiety in the oriental countries. A recent report revealed that RP attenuated ischemia-induced neuronal damage and kainite-induced convulsions in animals. This study was performed to investigate whether RP enhances pentobarbital-induced sleep behaviors and modulates sleep architecture in mice. Locomotor activity was significantly inhibited by RP at 0.25 and 0.5 mg/kg, similar to 2 mg/kg diazepam (a benzodiazepine agonist) in mice. RP shortened sleep latency and increased total sleep time in a dose-dependent manner when administrated with pentobarbital (42 mg/kg, i.p.). RP also increased the number of sleeping mice and total sleep time by concomitant administration with the sub-hypnotic dosage of pentobarbital (28 mg/kg, i.p.). On the other hand, RP (0.25 mg/kg, p.o.) itself significantly inhibited sleep-wake cycles, prolonged total sleep time, and rapid eye movement in rats. In addition, RP also increased chloride influx in the primary cultured hypothalamic neuronal cells. In addition, we found that glutamic acid decarboxylase ($GAD_{65/67}$) was activated by RP. In conclusion, RP augments pentobarbital-induced sleeping behaviors, and can be a candidate for treating insomnia.

• Advances in Traditional Medicine
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• 제6권1호
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• pp.21-26
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• 2006

The ethanolic extract of Fleurya interrupta Gaud, (Urticaceae) was tested for its possible neuropharmacological effects on experimental animals, For the primary neuropharmacological screening of this plant, the ethanolic extract of its aerial parts was subjected to preliminary evaluation for acute toxicity, antinociceptive activity and central nervous system (CNS) activities. At the doses of 125 and 250 mg/kg, the extract significantly (P < 0.01 and P < 0. 001) and dose-dependently increased the frequency of acetic acid induced writhing in mice. In the pentobarbitone induced sleeping time test, the extract at the above dose levels, significantly and dose-dependently decreased the pentobarbitone induced sleeping time (P < 0.001) and increased the time for onset of sleep (P < 0.001) in mice. In the open field and hole cross tests, test animals showed an increase in their movement in the both tests from the 2nd observation period (30 min) and persisted throughout the entire experimental period (240 min). These results of the extract may attribute a stimulating action on the CNS. On the basis of these findings, it can be assumed that the extract exerts its stimulating effect on the CNS in mice by interfering with the cortical function or increasing the effect of some CNS stimulating neurotransmitters.

• 동의생리병리학회지
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• 제25권4호
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• pp.614-619
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• 2011

Nelumbo nucifera(NN) is a oriental medicinal herb which has been used traditionally for the treatment of antidiarrhea, sedative action and various brain diseases including convulsion and epilepsy. In order to examine the mechanism of anticonvulsive effect, we treated the methanol extract of NN(100, 200 mg/kg, P.0) to the sleeping time and pentylenetetrazole(PTZ)-induced convulsive mice. The methanol extract of NN prolonged sleep time by pentobarbital. Methanol extracts of NN were not effected the concentration of GABA and GABA-T activity in the brain of PTZ-induced mice. Methanol extracts of NN significantly inhibited the convulsion state as well as the level of lipid peroxidation in the brain. The butanol and dichloromethane fraction of methanol extracts among the others effectively inhibited in vitro lipid peroxidation dose dependently($5.0{\times}10^{-6}\sim2.0{\times}10^{-5}\;g/ml$). These results suggest that the anticonvulsive effect of NN is possibly due to the antioxidative effects of the free radical formation at brain for the PTZ-induced convulsion if it were by due to generating system.

• 대한한방소아과학회지
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• 제11권1호
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• pp.205-226
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• 1997

Sanpoongdan(SPD) has been known effective on infantile convulsive disorders in clinical field of oriental medicine. The purpose of this study was to investigate the anti-convulsive, sedation and analgesic effects of SPD in mouse. The anticonvulsive effect was evaluated In mice treated with pentylenetetrazol, stychnine, and picrotoxin. For the sedative effect, observations were made on the sleeping time induced by thiopental sodium and pentobarbital sodium following oral administration of SPD. Furthermore, reduction of spontaneous movements and ataxia using rota rod method were evaluated. Analgesic effects on the writhing syndrome induced by acetic acid and on hindlimb pain induced by pressure were also observed. The findings were as follows : 1. The solid extracts of SPD revealed no effect on convulsions induced by pentylenetetrazol, strychnine, and picrotoxin. 2. Thiopental sodium-induced sleeping time was prolonged by the administration of the solid extracts of SPD, but this result was devoid of statistical significance. 3. The oral administration of SPD enhanced the sleeping induced by pentobarbital sodium. 4. Spontaneous movements were significantly depressed following the oral administration of the solid extracts of SPD. 5. Ataxia was not shown in rota rod method following the oral administration of the solid extracts of SPD. 6. The solid extracts of SPD showed positive analgesic effects on the acetic acid-induced writhing syndrome. 7. The solid extracts of SPD raised the threshold of the hindlimb pressure pain, but the result was not statistically significant. From the results, it can be concluded that SPD has sedative and analgesic effects.

• Biomolecules & Therapeutics
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• 제22권4호
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• pp.314-320
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• 2014

This study was investigated to know whether pachymic acid (PA), one of the predominant triterpenoids in Poria cocos (Hoelen) has the sedative-hypnotic effects, and underlying mechanisms are mediated via ${\gamma}$-aminobutyric acid (GABA)-ergic systems. Oral administration of PA markedly suppressed locomotion activity in mice. This compound also prolonged sleeping time, and reduced sleep latency showing synergic effects with muscimol (0.2 mg/kg) in shortening sleep onset and enhancing sleep time induced by pentobarbital, both at the hypnotic (40 mg/kg) and sub-hypnotic (28 mg/kg) doses. Additionally, PA elevated intracellular chloride levels in hypothalamic primary cultured neuronal cells of rats. Moreover, Western blotting quantitative results showed that PA increased the amount of protein level expression of $GAD_{65/67}$ over a broader range of doses. PA increased ${\alpha}$- and ${\beta}$-subunits protein levels, but decreased ${\gamma}$-subunit protein levels in $GABA_A$ receptors. The present experiment provides evidence for the hypnotic effects as PA enhanced pentobarbital-induced sleeping behaviors via $GABA_A$-ergic mechanisms in rodents. Taken together, it is proposed that PA may be useful for the treatment of sleep disturbed subjects with insomnia.

• 동의신경정신과학회지
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• 제11권2호
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• pp.53-62
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• 2000

Background : The aim of this study was to evaluate the effect of Punsimgieumgamibang on insomnia and anxiety. which is widely used in mental diseases. Method : We admitted Punsimgieumgamibang into rats which illumination of the sleeping periodhas been reversed, and measured its activity rate during the sleeping period. Also we studied the effect of Punsimgieumgamibang on anxiety using analyses of Punsimgieumgamibang on anxiety using analyses of behavior of rats submitted to the elevated plus-maze test.Result : 1) The sleeping ratio of the Pusimgieumgamibang group was higher than the control group on the whole, and the difference of the groups in the third time block was significant statistically. 2) We could not find any statistical information in all of the 4 anxiety related behavior of the elevated plus-maze experiment. and there was a tendency to a higher measurement in the Punsimgieumgamibang group animals in the total arms visitation in the elevated plus-maze, open arms visitation, and the amount of time of stay in arms. Conclusion : It is suggested that Pusimgieumgamibang has effects on insomnia.