• Sleep Medicine and Psychophysiology
• /
• v.7 no.1
• /
• pp.5-9
• /
• 2000

Several nonpharmacological treatment methods of insomnia and their effects were reviewed. A long-term use of most hypnotics may produce tolerance, dependence, cognitive and psychomotor impairments at daytime, shallow sleep, and rebound insomnia on drug withdrawal. To reduce hypnotic abuse, nonpharmacological strategies have been developed to correct disordered behavioral and cognitive factors. These treatments aim at modifying maladaptive sleep habits, lowering physiological and cognitive arousal levels, and correcting dysfuctional beliefs and attitudes about sleep. These non-pharmacological or cognitive behavior treatments include stimulus control, sleep restriction, relaxation training, sleep hygiene education, cognitive therapy, and light therapy. Among them the stimulus control therapy has been demonstrated most effective as a single treatment or in combination with other treatments. Through nonpharmacological treatments, sleep latency was most significantly reduced and wake time after sleep onset was also reduced. About 50% of insomniacs reported clinical improvements in terms of nearly normalized sleep latency, awakening time, sleep efficiency, and reduction of hypnotic use. Compared to the hypnotic therapy, nonpharmacological treatments are more cost-effective and more readily accepted by patients, and their effects last longer.

• Journal of the Ergonomics Society of Korea
• /
• v.15 no.2
• /
• pp.37-49
• /
• 1996

Morningness-Eveningness Questionnaire (MEQ) of Horne & Ostberg(1976) was translated into a Korean version, and MEQ and life habit inventory was administrated with approximately 900 university students. The distribution of MEQ score was normal. Arising time and bedtine for weekdays and holidays came in the order of morning type, intermediate and evening-type. And the deviation for the evening-type was greatest. Also, the deviation of sleep length for the evening-type was greater than the morning- type. There were tendencies that the bed time and arising time of the male were slightly later than those of the female, and the sleep length of the male was a little longer than that of the female. It also appeared that the arising time was later in the male who completed the military services than those who did not in the chronotype. And the sleep length of the non-served male was longer than that of the served one. Such tendencies noticeably appeared especially the evening-type. The evening-type was subject to heavy variability in bedtime. arising time, and sleep length. The sleep latency of the evening- type was longer and mood on arising was worse. And the ratio of nap or light sleep was higher in these subjects than in others. These results suggested that evening-type students had more irregular and/or flexible sleep-wake habits than the morning-type.

• Sleep Medicine and Psychophysiology
• /
• v.2 no.2
• /
• pp.171-179
• /
• 1995

Objectives : This study was carried out to determine whether the state anxiety may affect sleep on the night before surgery. Methods : The researcher examined the clinical charts of patients who were scheduled to receive surgery by general anesthesia the following day and then had semistructural interview with patients. In addition Spielberger's State Anxiety Inventory(1972), presleep questionnaire and postsleep questionnaire were administered to the patients. One hundred patients who responded to the questions were divided into three groups based on the state anxiety scores; low(n=35), middle(n=27) and high(n=38). Demographic and clinical characteristics of patients, some possible factors affecting sleep, daytime status and nighttime sleep before surgery were compared among three groups. Results : 1) There was no significant difference in demographic characteristics and some possible factors affecting sleep on the night before surgery among three groups. 2) In terms of clinical characteristics, the expectancy of surgical result was significantly different among three groups. More patients in low anxiety group than in middle and high anxiety groups, predicted surgical results as good, while more patients in middle and high anxiety groups than in low anxiety group could not predict their surgical results. 3) For daytime status, high anxiety group felt more tired compared to low anxiety group, but there was no significant difference in daytime nap among three groups. 4) For nighttime sleep before surgery, high anxiety group expected poor sleep and in fact, waked more frequently during sleep than low anxiety group. However there was no difference in bed time, sleep latency, rise time, total sleep time, sleep depth and sleep quality among three groups. 5) The need for hypnotics was higher before bedtime and also after rise in high anxiety group compared to low anxiety group. Conclusions : These results indicate that the individuals with high state anxiety before surgery have poor sleep and furthermore suggest that anxiolytics and/or hypnotics may be required to decrease anxiety and improve sleep for those with high state anxiety.

• Journal of the Korea Academia-Industrial cooperation Society
• /
• v.21 no.5
• /
• pp.372-383
• /
• 2020

This study analyzed the influence of Korean adults sleep time on psychological symptoms, suicidal ideation and attempts considering gender differences. The data was collected from the community health survey in 2017 with 228,381 people. When categorizing them into male and female, logistic regression analysis was conducted and the main analysis results are as follows. First, there are more women with shorter or longer sleep time than men. Second, in case of shorter sleep time (5 hours and less), stress, depression, and the suicidal ideation rates were high while suicidal attempts were higher in case of sleep greater than 9 hours and more. Third, in case of men, based on 6~8 hours of sleep time, people with shorter sleep time showed higher stress (1.84 times), depression (1.98), suicidal ideation (1.88), and attempts (2.38). People with 9 hours and more sleep showed greater depression (1.79), suicidal ideation (1.96) and attempts (2.39). Fourth, in the case of women, people with shorter sleep time showed greater stress (2.09), depression (1.94), suicidal ideation (1.96), and attempts (2.90). People with longer sleep showed greater depression (1.39), suicidal ideation (1.45) and attempts (1.71). Fifth, people's stress with greater sleep for both genders was higher than that of people with normal sleep. but there was no significant difference. Further prospective studies are needed on specific sleep dysfunctions effects on suicidal ideation and attempts.

• Journal of Physiology & Pathology in Korean Medicine
• /
• v.36 no.1
• /
• pp.7-10
• /
• 2022

Hwangryunagyo-tang (HT) is a herbal cocktail to treat insomnia induced by yin deficiency with effulgent fire. In the present study, the onset time and the duration time of sleep were measured 30 minutes after thiopental sodium injection. And c-fos immunohistochemistry was performed to find the activated nerve cells of the ventrolateral preoptic nucleus (VLPO) and tuberomammillary nucleus (TMN) sites in the brain. HT significantly increased the number of activated nerve cells in the sleep-inducing center (VLPO), whereas HT significantly decreased the number of activated nerve cells in the arousal center (TMN). It could be concluded that the HT shortened the onset time and increased the duration time for sleep induced by thiopental sodium. And it was confirmed that the mechanism acted by activating the sleep-inducing center (VLPO) and suppressing the arousal center (TMN) in the brain. The results are considered to be useful as scientific evidence HT can be used clinically for the treatment of insomnia caused by yin deficiency with effulgent fire.

• Journal of Korean Critical Care Nursing
• /
• v.15 no.3
• /
• pp.115-127
• /
• 2022

Purpose : This study aimed to investigate sleep parameters and to identify differences according to respiratory support therapy, sedation, and pain medication in intensive care unit (ICU) patients. Methods : In this observational study, sleep parameters were measured using actigraphy. We observed 45 sleep events in 30 ICU patients receiving respiratory support therapy. We measured the sleep parameters, time, efficiency, and wakefulness after sleep onset (WASO). The differences in sleep parameters according to the respiratory support therapy were analyzed using the Mann-Whitney U test. Results : The average daily sleep time of the participants was 776.66±276.71 minutes, of which more than 60% accounted for daytime sleep. During night sleep, the duration of WASO was 156.93±107.91 minutes, and the frequency of WASO was 26.02±25.82 times. The high flow nasal cannula (HFNC) group had a significantly shorter night sleep time (𝑥²=7.86, p =.049), a greater number of WASO (𝑥²=5.69, p =.128), and a longer WASO duration (𝑥²=8.75, p =.033) than groups of other respiratory therapies. Conclusion : ICU patients on respiratory support therapy experienced sleep disturbances such as disrupted circadian rhythm and sleep fragmentation. Among respiratory support regimens, HFNC was associated with poor sleep parameters, which appears to be associated with the insufficient use of analgesics. The results of this study warrant the development of interventions that can improve sleep in ICU patients receiving respiratory support, including HFNC.

• Journal of IKEEE
• /
• v.22 no.3
• /
• pp.862-865
• /
• 2018

The proposed scheme minimizes the Idle time under the residual energy of the sensor node to adjust the Sleep-Wakeup period and minimize unnecessary energy consumption. It is The proposed scheme minimizes the Idle time under the residual energy of the sensor node to adjust the Sleep-Wakeup period and minimize unnecessary energy consumption. It is an important process to control the Application Packet Framework including the PHY and the MAC layer at each node's Idle time with the Idle time mechanism state before the proposed function is executed. The Current Control Level of the Report Attribute is fixed at one sending / receiving node where power consumption can occur, by changing Sleep-Wakeup time, the low power consumption efficiency was improved while satisfying the transmission requirement of the given delay time constraint.

• Natural Product Sciences
• /
• v.22 no.4
• /
• pp.263-269
• /
• 2016

Rhynchophylline (RP) is a major tetracyclic oxindole alkaloid of Uncariae Ramulus et Uncus which has been used to treat hypertension, seizures, pain and anxiety in the oriental countries. A recent report revealed that RP attenuated ischemia-induced neuronal damage and kainite-induced convulsions in animals. This study was performed to investigate whether RP enhances pentobarbital-induced sleep behaviors and modulates sleep architecture in mice. Locomotor activity was significantly inhibited by RP at 0.25 and 0.5 mg/kg, similar to 2 mg/kg diazepam (a benzodiazepine agonist) in mice. RP shortened sleep latency and increased total sleep time in a dose-dependent manner when administrated with pentobarbital (42 mg/kg, i.p.). RP also increased the number of sleeping mice and total sleep time by concomitant administration with the sub-hypnotic dosage of pentobarbital (28 mg/kg, i.p.). On the other hand, RP (0.25 mg/kg, p.o.) itself significantly inhibited sleep-wake cycles, prolonged total sleep time, and rapid eye movement in rats. In addition, RP also increased chloride influx in the primary cultured hypothalamic neuronal cells. In addition, we found that glutamic acid decarboxylase ($GAD_{65/67}$) was activated by RP. In conclusion, RP augments pentobarbital-induced sleeping behaviors, and can be a candidate for treating insomnia.

• Sleep Medicine and Psychophysiology
• /
• v.9 no.1
• /
• pp.5-8
• /
• 2002

Stroke is a leading cause of death in most developed countries and some developing countries including South Korea. It is well known that stroke has is related in some way with several sleep disorders. At first, the onset time of stroke varies according to circadian rhythm. Early morning is the most prevalent time and late evening the least. The changes of blood pressure, catecholamine level, plasminogen activity and aggregation of platelet during sleep have been suggested as possible mechanisms. Sleep apnea (SA), a representative disorder in the field of sleep medicine, is found in more than 70% of acute stroke patients compared to 2-5% of the general population. Various sleep related breathing disorders occur after stroke and snoring is a distinct risk factor for stroke. So the relationship between stroke and SA is obvious, but the cause and effect are still not clearly known. Also, stroke may cause many sleep related problems such as insomnia, hypersomnia, parasomnia and changes in sleep architecture. Patients, family members and even medical personnel often ignore stroke-related sleep problems, being concerned only about the stroke itself. The clinical impacts of sleep problems in stroke patients may be significant not only in terms of quality of life but also as a risk factor or prognostic factor for stroke. More attention should be paid to the sleep problems of stroke patients.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
• /
• v.20 no.3
• /
• pp.146-151
• /
• 2009

Objectives : We conducted this study to investigate the relationship between sleep duration and body mass index (BMI), in Korean children. Methods : We performed a cross-sectional analysis of data collected on 3,639 boys and girls (aged 7-12) in Daegu, Korea. The data included each child's age, sex, weight, height, extracurricular activities, bedtime, wake-up time, sleep latency, total sleep duration, parents' occupations, and parents' educational levels. The relationship between sleep duration and each variable was examined via analysis of variance (ANOVA). Results : The analysis showed an association between short sleep duration and high BMI. Boys showed a graded inverse relationship between sleep duration and BMI. However, there was no significant corresponding result for girls. In the total sample, hours of computer use, time when the computer was turned off, time when the television was turned off, mother's bedtime, and hours of extracurricular activity were associated with longer sleep duration. No association was found between sleep duration and hours of watching television, child's wake-up time, or educational level of the parents. Conclusion : The results of this study show an inverse relationship between a child's sleep duration and BMI；thus, children with shorter sleep duration tend to have higher BMIs.