• The Korean Journal of Food And Nutrition
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• v.36 no.5
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• pp.403-414
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• 2023

This study aimed to determine the anti-obesity effect of adding Wolfiporia extensa Ginns (W) to fermented pollack skin products in an obesity-induced animal model. The experimental groups were the normal diet group (C), high-fat diet group (HF), dried pollack skin (H1), fermented pollack skin (H2), and W of 0.1 (F2-WL), 0.3 (F2-WM), and 0.5 (F2), respectively. It was confirmed that adding W to fermented pollack skin reduced blood triglycerides, total cholesterol, and LDL levels, while increasing HDL levels. Wolfiporia extensa Ginns was effective in controlling weight and improving blood lipids in a dose-dependent manner. In histological analysis, findings of fatty liver induced by a high-fat diet were improved by the addition of H2 and W. Size and density of fat globules in the epididymis were decreased. In addition, the concentration of TNF-α was increased in the high-fat diet group, but decreased by the addition of fermented pollack skin and W. In conclusion, adding fermented dried pollack skin and Wolfiporia extensa Ginns was effective for weight control and blood lipid improvement. Thus, the use of by-products in functional foods is expected to have a high value in the future.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.47 no.2
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• pp.133-138
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• 2021

In this study, Niacinamide (NI) was loaded into solid lipid nanoparticles (SLNs) and skin permeability was evaluated to improve skin permeability of NI, which was a skin whitening substance. NI was able to effectively load within SLN with a double-melting emulsification method, producing stable particles with average particle sizes of 263.30 to 436.93 nm and a zeta potential of -34.77 to -57.60 mV. Artificial skin tissue (SkinEthic^TM RHE) derived from skin keratinocytes derived from human epidermal tissue was used for the skin permeation study of NI. Skin transmittance and deposition experiments of NI confirmed that all SLN formulations improved skin transmittance and deposition rates of NI, approximately 5.4 ~ 7.6 and 9.5 ~ 20.8 improvement over SLN applications. Therefore, SLN manufactured in this study have shown sufficient results to improve the skin permeability of the functional whitening substance, NI.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.50 no.3
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• pp.261-270
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• 2024

In this study, the effects of relieving itching and improving the barrier due to moisturizing human skin were evaluated for the cream containing Siraitia grosvenorii extract, which is effective in suppressing histamine and improving skin inflammation in the study subjects with itching. 43 female volunteers aged 21 ~ 59 years old (experimental group: 21 and control group 22) suitable for the purpose of the study were used for 4 weeks on the anterior gourd. The evaluation measured the amount of skin moisture and transepidermal moisture loss (TEWL) in the left or right anterior gourd before and after use of the product, and the visual analogue scale (VAS) evaluation due to skin drying, the efficacy and usability questionnaire evaluation of the product, and skin safety evaluation were conducted. As a result of the analysis, compared to before product use, both the experimental group and the control group showed significant improvement effects according to product use 4 weeks after use on the evaluation items of skin moisture and transepidermal moisture loss and the VAS due to skin dryness. In particular, the experimental group showed a significant improvement effect compared to the control group. As a result of the survey on the efficacy and usability of the product, the subjects of the study in the test group showed higher satisfaction than the control group in the case of the items "relieving itching (suitable)", "moisturizing" and "smoothing" after four weeks of use. In terms of usability, the subjects of the study in the experimental group showed higher satisfaction than the control group in the case of the "scent" and "feeling" items. Based on the above results, it is believed that "cream containing S. grosvenorii extract" has an itch relief (barrier improvement) effect due to skin moisturizing and can be used as a functional product for itching and barrier function improvement.

• Journal of Pharmacopuncture
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• v.16 no.2
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• pp.41-45
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• 2013

Objective: The root bark of Ulmus davidiana var. Japonica (Ulmi Radicis cortex, URC) is a medicinal herb used for promoting diuresis and treating dampness. In Korea, URC has long been used as an efficacious therapy for inflammation, burns, frostbite and skin diseases such as eczema and psoriasis. Methods: In the present study, we used 1-fluoro-2,4-dinitrofluorobenzene (DNFB)-induced contact dermatitis (CD) mouse model to investigate the anti-allergic and the anti-inflammatory effects of URC on skin lesion, histopathological changes and specific antibody production. Results: URC treatment, 10 mg/mL, effectively inhibited skin lesions induced by repeated paintings with DNFB. In the histopathological observation, topical application of URC inhibited spongiosis. In addition, URC lowered the production levels of total immunoglobulin and IgG2a in serum. Conclusion: These data indicate that URC has an anti-inflammatory effect that produces an improvement of skin lesions in CD mice.

• Journal of Veterinary Clinics
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• v.25 no.6
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• pp.466-470
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• 2008

The purpose of this study is to investigate whether the effects of topically applied petrolatum and glycerin on the barrier repair of acetone-induced skin damage in 6 beagle dogs. To confirm the effects of petrolatum and glycerin on acetone disrupted skin models, we performed to evaluate the characteristics of transepidermal water loss and SC hydration and scanning electron microscopic observations. TEWL and SC hydration measurements were carried out 3, 6, 12, 24, 48h after applying petrolatum and glycerin during recovery from acute disruption. Our results showed that there were some different effects between petrolatum and glycerin on the acetone damaged skin such as barrier function repair process and SC hydration status. The results indicate that the significant improvement could be observed in glycerin apply more than petrolatum after acetone damages, and further study will be required.

• Textile Coloration and Finishing
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• v.26 no.3
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• pp.181-186
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• 2014

This paper surveys improvement characteristics in muscle fatigue with bio-activity material imbedded fabric. For this purpose, the subjects wear the garment which is covered by bio-activity materials all over every day during 2 weeks of experimental period. After 2 weeks period, VAS(Visual Analogue Scale) index evaluation regarding muscle fatigue and pain has been conducted in comparison between before wearing and after so that we can evaluate the effect on muscle fatigue improvement. The effectiveness survey for testing products consists of improvement on krunkle, muscle fatigue and exercise capacity. As a result, 100% of test subject group completes a questionnaire with positive answer as above normal in every question. In addition the preference of testing products is researched in wearing comfort, activity and convenience. And it is marked above normal by 100% of test subject group as well. Moreover any kind of unusual skin reaction has not been detected in safety evaluation. Therefore this testing products is being judged as a beneficent product for improvement on muscle fatigue without any skin irritation.

• Journal of the Korea Fashion and Costume Design Association
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• v.16 no.1
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• pp.153-167
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• 2014

The purpose of this study is to compare and analyze about the Telecasters's appearance management, external image & awareness on Self-Efficacy. The method of this study is carried out form 2 January 2013 until 20 January. with the 164 telecasters who announcers, voice actors, gag men, singers. The results of the research is summarized below: First, Among the telecasters, singer is the highest awareness of the beauty services importance about the fashion, makeup, hair, skin care, cosmetic surgery. Especially, about the awareness of the beauty services importance about the fashion, makeup, hair, singers> announcers> voice actors> gagmen appear one after another. Second, about the importance awareness of the beauty services importance & the relation of self-efficacy, for announcers, the more higher awareness the fashion, makeup, hair, the higher self-efficacy of the confidence, effective expression, etc.. For voice actors, the more higher awareness the hair, skin care, the fashion, make up, cosmetic surgery, the higher self-efficacy of the new image making, the confidence, task efficiency improvement, etc... For gagmen, the more higher awareness the fashion, hair, skin care, makeup, cosmetic surgery, the higher self-efficacy of the self-expression, the confidence, the new image making, task efficiency improvement, etc.. For singer, the more higher awareness the makeup, hair, cosmetic surgery, skin care, fashion, the higher self-efficacy of the task efficiency improvement, the self-expression, the confidence, the new image making, etc.. Third, about the importance awareness of the appearance management behavior, external image, about the importance awareness of the appearance management behavior, singer is the most higher awareness, announcers> voice actors> gagmen appear one after another. about the importance awareness of the external image, singer is the most higher awareness, voice actor> announcers> gagmen appear after another. The meanings of this study provide the telecasters's image's fields with the effective basic data.

• Applied Biological Chemistry
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• v.39 no.4
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• pp.274-281
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• 1996

To prepare edible skin gelatin of conger eel such as material fur quality improvement of surimi gel, the defatted skin was limed with 1% calcium hydroxide at $5^{\circ}C$ for 2 days, washed thoroughly with tap water, extracted with 8 volumes of distilled water to dehydrated skin for 2 hours at $50^{\circ}C$. The gelatin extract was centrifuged, filtered and then passed through anion(Amberlite 200C) and cation (Amberlite IR 900) resins. The purified gelatin solution was evaporated and dried by hot-air blast$(40^{\circ}C)$. The gelatin prepared by above condition had the highest quality as revealed by physical property values i.e. 240.5 g in gel strength, $28.0^{\circ}C$ in melting point and $28.0^{\circ}C$ in gelling point. Funtional property values were 56.8% in solubility, 1.8 ml/g in oil binding capacity, 55.0% in emulsifying capacity and 48.5% in emulsifying stability. jelly strength and senso교 evaluation of surimi gel from fish with red muscle were not improved by addition of emulsifying curd from conger eel skin gelatin as emulsifier. Therefore, the conger eel skin gelatin requires a suitable modification of functional group and improvement of processing operation to utilize as a material for quality Improvement of surimi gel.

• Archives of Plastic Surgery
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• v.37 no.2
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• pp.153-160
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• 2010

Purpose: The prevalence of skin cancers and cutaneous premalignant lesions are increasing recently. It is necessary to treat cutaneous premalignant lesions, because these can progress to invasive skin cancers. We conducted a retrospective study to evaluate the usefulness of $CO_2$ laser resurfacing in skin tumor surgery. Methods: From 2005 to 2008, 14 patients with skin cancers, photodamaged skin and cutaneous premalignant lesions were treated with skin cancer excision, immediate reconstruction, and $CO_2$ facial laser resurfacing. Mean average follow-up period was 15.6 months (5 months - 36 months). Biopsy and clinical photograph were taken preoperatively, intraoperatively and through follow-up period to assess the effectiveness of laser resurfacing. Recurrence and side effects were evaluated through follow-up period. Results: Histologic examination shows the abolition of actinic atypia, regeneration of epidermis and normalization of cellular differentiation after laser resurfacing. Clinical photographs shows elimination of keratoses and spots, and the homogeneous, smoothening change of skin surface, indicating healthy and younger faces. All patients had remained free of skin cancers and premalignant lesions in laser-treated field through follow-up period. Conclusion: $CO_2$ laser resurfacing in skin tumor surgery can treat not only premalignant lesions but also subclinical lesions of photodamaged skin. Moreover it may be helpful in prophylaxis against skin cancers and premalignant lesions, providing rejuvenation and cosmetic improvement.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.26 no.4
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• pp.533-540
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• 2022

Specialists diagnose skin cancer using a dermatoscopy to detect skin cancer as early as possible, but it is difficult to determine accurate skin lesions because skin lesions have various shapes. Recently, the skin lesion segmentation method using deep learning, which has shown high performance, has a problem in segmenting skin lesions because the boundary between healthy skin and skin lesions is not clear. To solve these issues, the proposed method constructs a transformer block to effectively segment the skin lesion, and constructs an edge decoder for each layer of the network to segment the skin lesion in detail. Experiment results have shown that the proposed method achieves a performance improvement of 0.041 ~ 0.071 for Dic Coefficient and 0.062 ~ 0.112 for Jaccard Index, compared with the previous method.