• Journal of Preventive Medicine and Public Health
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• v.17 no.1
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• pp.121-126
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• 1984

Several detailed aspects of medical care services during one year (Aug 1, $1982{\sim}$July 31, 1983) were compared between two community health sub-centers; one (A) was served by a local clinician, the other (B) by a trainee of preventive medicine. The results were analysed as follows: 1. Total spells of medical services during the same period in 'A' sub-center was 4,087 and that in 'B' 2,347. Medicaid visitors in 'A' was 1,051 (25.7% of the total), that in 'B' was 250 (10.7%). Significant difference was observed. 2. Average number of visits for the same case in 'A' was 2.0, that in 'B' was 1.4. Average duration of service by day for the same case in 'A' was 3.9, that in 'B' 3.0. 3. Average cost of service for a case in 'A' was 6,770 won, that in 'B' 4,230 won. 4. Difference in age distribution of visitors in the two sub-centers was insignificant. $0{\sim}9$ year group was 38.5% of the total. Difference in distribution by sex (between two sub-centers) was minimal. Male utilisers more than female by ca. 10%. 5. Concerning distribution of visitors by month, utilisation in July, August and September was the highest; the sum of them was 32.7% of the total in 'A' and 32.9% in 'B'. 6. Distribution by diagnoses in 'A' in decreasing order of frequency was Respiratory system diseases (26.1%), Digestive system diseases (23.0%), Diseases of skin and subcutaneous tissue (17.4%), Accidents and poisoning (11.5%) and Diseases of musculoskeletal system and connective tissue (5.4%). That in 'B' was Respiratory system diseases (39.0%), Digestive system diseases (23.0%), Diseases of skin and subcutaneous tissue (14.2%), Accidents and poisoning (10.9%) and Infection and parasitic diseases (9.1%). 7. The 10 most frequent diagnoses comprised 68.5% of the total in 'A' and 65.5% in 'B' 8. Utilisation by accessibility to each sub-center was studied. It is shown that the nearer the distance or the easier the accessibility, the more visits to services. The distinct pattern is manifested in the utilisation in 'A'-Myun.

• Journal of Korean Society of Occupational and Environmental Hygiene
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• v.29 no.4
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• pp.452-463
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• 2019

Objectives: The purpose of this study is to evaluate airborne concentrations of volatile organic compounds(VOCs) during nail art practice by college students. Methods: Personal samples for students were measured using passive samplers(OVM 3500) during three kinds of practice, including polish nail, gel nail and acrylic French sculpture at two universities located in Gyeongsangbuk-do Province. We also monitored area concentrations using active samplers and real-time total VOC monitors(ppbRAE 3000). All samples were analyzed with a gas chromatography flame ionized detector. Statistical analysis for monitored data were conducted using a web-based Bayesian toolkit, EXPOSTATS(www.expostats.ca). Results: Twenty-four personal samples and ten area samples were collected and five chemicals(acetone, butyl acetate, ethyl acetate, ethyl methacrylate(EMA) and methyl methacrylate(MMA)) were detected. Acetone was detected in all personal samples and ranged from 2.58 ppm to 50.3 ppm. EMA was detected in all personal and area samples with a maximum concentration of 9.78 ppm during acrylic French sculpture. Personal exposure levels to acetone, butyl acetate and mixtures were significantly higher with high occupant density (p<0.05). Geometric mean (GM) concentrations of 3.61 ppm for EMA personal samples were significantly higher than that of area samples, 1.5 ppm (p<0.05). Since there was no local ventilation, total VOC concentration continued to increase as the practice progressed. Conclusions: In order to minimize VOCs exposure for trainees, it is necessary to introduce a local ventilation system and maintain adequate occupant density.

• Safety and Health at Work
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• v.9 no.2
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• pp.149-158
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• 2018

Background: Work comfort studies have been extensively conducted, especially in the underground and meteorological fields resulting in an avalanche of recommendations for their evaluation. Nevertheless, no known or universally accepted model for comprehensively assessing the thermal work condition of the underground mine environment is currently available. Current literature presents several methods and techniques, but none of these can expansively assess the underground mine environment since most methods consider only one or a few defined factors and neglect others. Some are specifically formulated for the built and meteorological climates, thus making them unsuitable to accurately assess the climatic conditions in underground development and production workings. Methods: This paper presents a series of sensitivity analyses to assess the impact of environmental parameters and metabolic rate on the thermal comfort for underground mining applications. An approach was developed in the form of a "comfort model" which applied comfort parameters to extensively assess the climatic conditions in the deep, hot, and humid underground mines. Results: Simulation analysis predicted comfort limits in the form of required sweat rate and maximum skin wettedness. Tolerable worker exposure times to minimize thermal strain due to dehydration are predicted. Conclusion: The analysis determined the optimal air velocity for thermal comfort to be 1.5 m/s. The results also identified humidity to contribute more to deviations from thermal comfort than other comfort parameters. It is expected that this new approach will significantly help in managing heat stress issues in underground mines and thus improve productivity, safety, and health.

• Journal of Convergence for Information Technology
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• v.9 no.11
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• pp.247-253
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• 2019

The purpose of this study was to identify the effects of work stress, burnout and compassion satisfaction of the estheticians. The sample consisted of 268 estheticians from esthetic-shop located in Seoul and Gyung-gi province. The questionnaire was organized into 4 items of general traits, 24 items of KOSS, and 10 items of burnout and compassion satisfaction from proQOL. Results show that estheticians experienced a greater than moderate degree of job stress, compassion satisfaction burnout, whereas differences existed according to general characteristics. but group was included in the top 75% of the factor on when compared to the Korean occupational stress scale. It is foreseeable that the burnout caused by the work of a estheticians is not small at all. This study is expected to be used as basic data in finding ways to reduce job stress and burnout of estheticians.

• Journal of Ginseng Research
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• v.44 no.6
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• pp.799-807
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• 2020

Background: The skin acts as a barrier to protect organisms against harmful exogenous agents. Compound K (CK) is an active metabolite of ginsenoside Rb1, Rb2 and Rc, and researchers have focused on its skin protective efficacy. In this study, we hypothesized that increased expression of the serine protease inhibitor Kazal type-5 (SPINK5) may improve skin barrier function. Methods: We screened several ginsenosides to increase SPINK5 gene promoter activity using a transactivation assay and found that CK can increase SPINK5 expression. To investigate the protective effect of CK on the skin barrier, RT-PCR and Western blotting were performed to investigate the expression levels of SPINK5, kallikrein 5 (KLK5), KLK7 and PAR2 in UVB-irradiated HaCaT cells. Measurement of transepidermal water loss (TEWL) and histological changes associated with the skin barrier were performed in a UVB-irradiated mouse model and a 1-chloro-2,4-dinitrobenzene (DNCB)-induced atopic dermatitis-like model. Results: CK treatment increased the expression of SPINK5 and decreased the expression of its downstream genes, such as KLKs and PAR2. In the UVB-irradiated mouse model and the DNCB-induced atopic dermatitis model, CK restored increased TEWL and decreased hydration and epidermal hyperplasia. In addition, CK normalized the reduced SPINK5 expression caused by UVB or DNCB, thereby restoring the expression of the proteins involved in desquamation to a level similar to normal. Conclusions: Our data showed that CK contributes to improving skin-barrier function in UVB-irradiated and DNCB-induced atopic dermatitis-like models through SPINK5. These results suggest that therapeutic attempts with CK might be useful in treating barrier-disrupted diseases.

• Safety and Health at Work
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• v.10 no.4
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• pp.409-419
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• 2019

Although the rare earth elements (REEs) recycling industry is expected to increase worldwide in hightech industry, regulations for worker safety have yet to be established. This study was conducted to understand the potential hazard/risk of REE recycling and to support the establishment of regulations or standards. We review the extensive literature on the toxicology, occupational safety, and health issues, and epidemiological surveys related to the REEs, and propose suitable management measures. REE recycling has four key steps such as collection, dismantling, separation, and processing. In these processes, hazardous substances, such as REEs-containing dust, metals, and chemicals, were used or occurred, including the risk of ignition and explosion, and the workers can be easily exposed to them. In addition, skin irritation and toxicities for respiratory, nervous, and cardiovascular systems with the liver toxicity were reported; however, more supplementary data are needed, owing to incompleteness. Therefore, monitoring systems concerning health, environmental impacts, and safety need to be established, based on additional research studies. It is also necessary to develop innovative and environment-friendly recycling technologies, analytical methods, and biomarkers with government support. Through these efforts, the occupational safety and health status will be improved, along with the establishment of advanced REE recycling industry.

• Korean Journal of Veterinary Service
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• v.41 no.2
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• pp.97-104
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• 2018

Recently, demographic studies of veterinary medical database have been conducted to understand patterns of disease occurrence. Understanding incidence of breed-related disease would provide appropriate guidance for future health care strategies and offer useful information for early diagnosis of disease. However, in veterinary medicine, theses research has not yet been investigated in the Republic of Korea. The purpose of this study was to investigate the prevalence of common medical disorders among dog breeds examined at primary-care veterinary clinics in Jeollabuk-Do, Republic of Korea. The data were analyzed based on World Health Organization's International Classification of Disease. A total 13,176 medical records of canine patients were analyzed from six primary veterinary clinics in Jeollabuk-Do from January to December 2016. Results showed that the most common health problems were 'disease of skin' (17.7%); followed by 'diseases of digestive system' (12.26%), 'preventive medicine' (10.08%), and 'diseases of ear and mastoid process' (10.4%). In seven out of ten breeds, the most common medical disorder was skin disease. For poodle such as Pomeranian and Chihuahua, digestive system disease was most prevalent. On the other hand, respiratory system disease was found to be higher in Pomeranian than other breeds; while ear and mastoid process disease was most common for Maltese and Poodle. This study can help owners, breeders, and veterinarians prevent and manage various diseases of popular breeds in Jeollabuk-Do in the future.

• Microbiology and Biotechnology Letters
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• v.44 no.2
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• pp.208-217
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• 2016

Pinus densiflora Sieb. et Zucc. (P. densiflora) contains several phenolic compounds that exhibit biological activities, such as antimicrobial, antioxidant, and antihypertensive effects. However, the anti-inflammatory effect of P. densiflora on skin has rarely been reported. Malassezia furfur (M. furfur) is a commensal microbe that induces skin inflammation and is associated with several chronic disorders, such as dandruff, seborrheic dermatitis, papillomatosis, and sepsis. The aim of our study was to identify the anti-inflammatory effects of P. densiflora needle extracts on skin health subjected to M. furfur-induced inflammation. The methanolic extract of the pine needles was partitioned into n-hexane, EtOAc, n-BuOH, and water layers. We measured the anti-inflammatory effects (in macrophages) as well as the antioxidant, antifungal, and tyrosinase inhibitory activity of each of these layers. The antioxidant activity of the individual layers was in the order EtOAc layer > n-BuOH layer > water layer. Only the n-BuOH, EtOAc, and n-hexane layers showed antifungal activity. Additionally, all the layers possessed tyrosinase inhibition activity similar to that of ascorbic acid, which is used as a commercial control. The EtOAc layer was not cytotoxic toward the RAW 264.7 cell line. Interleukin 1 beta and tumor necrosis factor (TNF)-α expression levels in M. furfur-stimulated RAW 264.7 cells treated with the EtOAc layer were decreased markedly compared to those in cells treated with the other layers. Taken together, we believe that the needle extracts of P. densiflora have potential application as alternative anti-inflammatory agents or cosmetic material for skin health improvement.

• Toxicological Research
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• v.34 no.1
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• pp.31-39
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• 2018

The objective of this study was to evaluate the antioxidant and anti-aging effects of marigold methanol extract (MGME) in human dermal fibroblasts. Total polyphenolic and flavonoid contents in MGME were 74.8 mg TAE (tannic acid equivalent)/g and 85.6 mg RE (rutin equivalent)/g, respectively. MGME ($500{\mu}g/mL$) increased 1,1-diphenyl-2-picryl hydrazyl (DPPH) and 2,2'-azino-3-ethylbenzothiazoline-6-sulfonic acid (ABTS) radical-scavenging, and superoxide dismutase (SOD)-like antioxidant activities by 36.5, 54.7, and 14.8%, respectively, compared with the control. At $1,000{\mu}g/mL$, these activities increased by 63.7, 70.6, and 20.6%, respectively. MGME ($100{\mu}g/mL$) significantly increased the synthesis of type 1 procollagen by 83.7% compared with control treatment. It also significantly decreased Matrix Metalloproteinase-2 (MMP-2) activity and MMP-1 mRNA expression by 36.5% and 69.5%, respectively; however, it significantly increased laminin-5 mRNA expression by 181.2%. These findings suggest that MGME could protect human skin against photo-aging by attenuating oxidative damage, suppressing MMP expression and/or activity as well as by stimulating collagen synthesis.

• Journal of the Korean Society of Clothing and Textiles
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• v.32 no.7
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• pp.1056-1064
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• 2008

Toes socks are used widely for the health of feet. However, discomfort is one of the major complains from toes socks users. The purpose of this study is to determine the effect of functional fibers on the physiological response and wearing sensation of toes socks. For experiment, two different toes socks with cotton/warm fiber(WS) and cotton/chitosan fiber(CS) were knitted automatically by a computer controlled flat knitting machine. The control toes socks with cotton/nylon/polyurethan(TS) were prepared to compare the properties. Experiments were conducted in a climate room of $16\pm2^{\circ}C$, $50\pm5%$ R.H. The results of this study were as follows. The change of heart rate, pulse rate, and mean skin temperature showed no difference among three different socks. However, skin temperature of TS was evaluated higher than that of WS and CS. After exercise wearing WS both instep temperature and sole temperature of women tend to higher compared to men. Wet sensation and overall comfort sensation of toes socks were significantly influenced by different fiber contents. Subjects evaluated WS and CS more comfortable than TS.