• Title/Summary/Keyword: skin and structure

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On the Composites of poly(ethylene 2,6-naphthalate) with a Thermotropic Block Copolyester(I) (열방성 블록 코폴리에스테르와 poly(ethylene 2,6-naphthalate)의 복합재료 연구(I))

  • Choi, Jae Kon
    • Applied Chemistry for Engineering
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    • v.8 no.3
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    • pp.454-462
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    • 1997
  • Thermotropic block copolyester(TLCP-b-PBN) based on poly(tetramethylene 2,6-(naphthaloyldioxy)dibenzoates)(TLCP) and poly(butylene 2,6-naphthalate)(PBN) was synthesized by solution polycondensation and melt-blended with poly(ethylene 2,6-naphthalate)(PEN) for in-situ composites. The TLCP domains showed nematic behavior in melt. The composition of block copolymer was determined from $^1H-NMR$ spectroscopy. The DSC thermogram of block copolymer revealed the presence of two major melting transitions, corresponding to the separete melting of PBN and TLCP domains. The glass transition temperature(Tg) of the PEN in the blends decreased with increasing the content of TLCP-b-PBN and the TLCP-b-PBN acted as a nucleating agent for the matrix polymers. In the 20% TLCP-b-PBN blend, well oriented TLCP fibriles were observed at temperature above the melting point of the PEN by optical microscopy. By scanning electron micrographs of cryogenically fractured surfaces of extruded blends, the TLCp domains were found to be finely and uniformely dispersed in 0.15 to $0.2{\mu}m$ size. Interfacial adhesion between the TLCP and matrix polymer was seemed to be good. Under certain condition TLCP formed a fiver structure in the PEN matrix, with thin oriented TLCP fibril in the skin region and spherical TLCP domains in the core.

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Effect of Rheum undulatum Extract on Antioxidant Activity and Activity of Matrix Metalloproteinase-1 in Human Skin Fibroblasts (대황 추출물의 항산화 활성 및 MMP-1 저해 활성)

  • Park, Sung-Min;Lee, Gye-Won;Cho, Young-Ho
    • Journal of Life Science
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    • v.18 no.12
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    • pp.1700-1704
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    • 2008
  • Rheum undulatum L. has been commonly used as a cure for hematemesis, dropsy, and haematuria in the Oriental medicine for a long time. The main constituents of R. undulatum are chrysophanol and emodin, which are an antioxidative substance that has an anthraquinone structure. In the present study, to develop a new anti-aging agent, we examined the antioxidant activity and the inhibitory effect of the R. undulatum extract on the synthesis of MMP-1 in UVA-irradiated human dermal fibroblasts and MMP-1 activity. The R. undulatum extract was found to scavenge 1,1-diphenyl-2-picrylhydrazyl (DPPH) radicals and superoxide radicals in the xanthine/ xanthine oxidase system by a dose-dependent manner, respectively. UVA-induced MMP-1 expression was reduced about 79.5% by 1 ${\mu}g$/ml of the R. undulatum extract and also inhibited MMP-1 activity in a dose-dependent manner. In conclusion, it was observed that the R. undulatum extract has the antioxidant activity, regulation of UVA-induced MMP-1 production, and inhibition of MMP-1 activity. Therefore, these results suggest that the R. undulatum extract can be developed as a new anti-aging component of cosmetics.

Efficiency of Essential oil about the Skintroubles induced Surfactants - Palmarosa, Neroli essential oil - (계면활성제 유발된 피부장애의 아로마 에션셜 오일의 유효성 연구 - Palmarosa, Neroli essential oil을 중심으로 -)

  • Jung, Hyun-Mee;Choi, Jeung-Sook
    • Fashion & Textile Research Journal
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    • v.8 no.3
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    • pp.331-335
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    • 2006
  • The effectiveness of Palmarosa and Neroli essential oil on dry skin of rat induced by kitchen detergent are investigated. The experimental groups were divided the control group (C), group treated with surfactant (A1), group treated with Palmarosa (A2), group treated with Neroli (A3), group treated with Palmarosa and Neroli (A4). The protein analysis of all experimental groups was performed with SDS polyacrylamide gel electrophoresis and observation of epidermis and the alteration of mast cell were performed with photomicroscope. According to the protein analysis, the A3 group treated with Neroli essential oil was appeared the most similar with the control group. And then the A4 group treated with Palmarosa + Neroli essential oil was appeared the most similar with the control group. According to the results of morphologic view with keratin layer, the keratin layer's breakaway resulting from Palmarosa essential oil, the keratin layer's restoration resulting from Neroli essential oil was appeared. And then the structure of the epidermal layer was preserved by hyperkeratosis reaction. In photomicrosopic obersevation of mast cell to examine the inflammatory reactions, the increase in size and number of mast cell were showed in A1 group treated with surfactant compared to the control group (C). The number of mast cells definitely decreased in groups (A3, A4) which were treated with Neroli essential oil.

A Study on the meaning of Database follow the application of Visual Contents (전시콘텐츠 적용 환경에 따른 데이터베이스 의미 고찰)

  • Kim, Min-Su;Yoon, Se-Kyun
    • Archives of design research
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    • v.18 no.1 s.59
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    • pp.17-26
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    • 2005
  • Nowadays, display-contents are developing to an informative environment. that is under the logic of the media operating system. To perceive the media-environments and produce the cultural contents, the cultural designers seek to understand a skin structure from making up for shape. To appreciate operating system in data and database is not only systematization of form and contents of visual contents but also variety contents into multiple-platform and integrative environments. These days, the spectacle exhibition try to express for their surface design between algorithm of data and database. the information is expressing aesthetic which means presents the integrated contents through the play instinct environment to end-user. That was given web or game to participation is developing with the cellular device and ubiquitous computing system. in the linear perspective, the end-user should be immerse more and more hyper-simulation system because of the operating algorithm of database. To do this, human have need to get the information-ability from multi-platform society. In the virtual environment, database offer the experience of an unheard-of event to end-user that prepare the participants the circumstances priority of signifiers. To do that already based on a fixed sensibility endow with narrative of the freshness- experience.

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A Study on Estimation of Motor Unit Location of Biceps Brachii Muscle using Surface Electromyogram (표면 근전도를 이용한 이두박근의 운동단위 위치 추정에 관한 연구)

  • Park, Jung-Ho;Lee, Ho-Yong;Jung, Chul-Ki;Lee, Jin;Kim, Sung-Hwan
    • Journal of the Institute of Electronics Engineers of Korea SC
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    • v.47 no.3
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    • pp.28-39
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    • 2010
  • In this paper, a new method to estimate MU (motor unit) location in the short head of BIC (biceps brachii) muscle using surface EMG (electromyogram) is proposed. The SMUAP (single motor unit action potential) is generated from a MU located at certain depth from the skin surface. The depth is referred as MU location. For estimating muscle force precisely, the information of the MU location is required. The reference SMUAPs are simulated based on anatomical structure of human muscle, and compared with acquired real EMG signals using 3-channel surface EMG electrode. The proposed method was compared with the results of previous researchers and verified its accuracy by computer simulation. From the simulation result in case of the MU located in 8[mm], the average estimation error of proposed method was 0.01[mm]. But the average estimation error of Roeleveld's method was 2.33[mm] and Akazawa's method was 1.70[mm]. Therefore the proposed method was more accurate than the methods of previous researchers.

Proteomic Analysis and the Antimetastatic Effect of N-(4methyl)phenyl-O-(4-methoxy) phenyl-thionocarbamate-Induced Apoptosis in Human Melanoma SK-MEL-28 cells

  • Choi Su-La;Choi Yun-Sil;Kim Young-Kwan;Sung Nack-Do;Kho Chang-Won;Park Byong-Chul;Kim Eun-Mi;Lee Jung-Hyung;Kim Kyung-Mee;Kim Min-Yung;Myung Pyung-Keun
    • Archives of Pharmacal Research
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    • v.29 no.3
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    • pp.224-234
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    • 2006
  • We employed human SK-MEL-28 cells as a model system to identify cellular proteins that accompany N-(4-methyl)phenyl-O-(4-methoxy)phenyl-thionocarbamate (MMTC)-induced apoptosis based on a proteomic approach. Cell viability tests revealed that SK-MEL-28 skin cancer cells underwent more cell death than normal HaCaT cells in a dose-dependent manner after treatment with MMTC. Two-dimensional electrophoresis in conjunction with matrixassisted laser desorption/ionization-time of flight (MALDI-TOF) mass spectrometry analysis or computer matching with a protein database further revealed that the MMTC-induced apoptosis is accompanied by increased levels of caspase-1, checkpoint suppressor-1, caspase-4, NF-kB inhibitor, AP-2, c-Jun-N-terminal kinase, melanoma inhibitor, granzyme K, G1/S specific cyclin D3, cystein rich protein, Ras-related protein Rab-37 or Ras-related protein Rab-13, and reduced levels of EMS (oncogene), ATP synthase, tyrosine-phosphatase, Cdc25c, 14-3-3 protein or specific structure of nuclear receptor. The migration suppressing effect of MMTC on SK-MEL-28 cell was tested. MMTC suppressed the metastasis of SK-MEL-8 cells. It was also identified that MMTC had little angiogenic effect because it did not suppress the proliferation of HUVEC cell line. These results suggest that MMTC is a novel chemotherapeutic and metastatic agents against the SK-MEL-28 human melanoma cell line.

A Study on the Dynamic Strength Analysis of the Hull Girder Among Waves Considering Non-Linear Hydrodynamic forces (선박의 비선형 유체력을 고려한 파랑중 동적 강도 해석법에 관한 연구)

  • Ku-Kyun Shin;Sa-Soo Kim;Sung-Wan Son
    • Journal of the Society of Naval Architects of Korea
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    • v.29 no.4
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    • pp.152-172
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    • 1992
  • The ship sailing among waves are suffered the various wave loads that comes from its motion throughout its life. Because there are dynamic, the analysis of ship structure must be considered as the dynamic problem precisely. In the rationally-based design, the dynamic structural analysis is carried out using dynamic wave loads provided from the results of the ship mouton calculation as the rigid body. This method is based on the linear theory assumed low wave height and small amplitude of motion. But at the rough sea condition, high wave height, relatively ship's depth, is induced the large ship motion, so the ship section configulation below water line is rapidly changed at each time. This results in non-linear problem. Considering above situation in this paper, the strength analysis method is introduced for the hull glider among waves considering non-linear hydrodynamic forces. This paper considers that the overall or primary level of the ship structural dynamic loading and dynamic response provided from the non-linear wave forces, and bottom and bow flare impact forces estimated by momentum slamming theory, in which the ship is idealized as a hollow thin-walled box beam using thin-walled beam theory and the finite element method. This method is applied to 40,000 Ton Double-Skin Tanker and attention is paid to the influence of the response of ship speed, wave length and wave height compared with linear strip theory.

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Bearing Behavior Characteristics of Pressure Penetrating Steel Pipe Pile Under Compression Load (압축하중을 받는 압입강관말뚝의 지지거동 특성)

  • Kwon, Ohkyun
    • Journal of the Korean GEO-environmental Society
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    • v.16 no.7
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    • pp.5-13
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    • 2015
  • The pressure penetrating steel pipe pile method which can be constructed in a narrow space using the hydraulic jack is used on the foundation reinforcement, extension of the structure and basement, restoration of the differential settlement etc.. This method is possible to construct in narrow areas and low story height, the non-noise and non-vibration works, and it is possible for the construction site to be clean without slime. And it is possible to confirm the bearing capacity of pile due to penetrating the pile with the compression load of hydraulic jack. In this study, the static load test with the load-transfer test was carried out to investigate the bearing behavior characteristics of the pressure penetrating steel pipe pile. Four series of static load test were executed to investigate the variation of bearing behavior of the pressure penetrating steel pipe pile. As a result of these tests, the allowable load of the pressure penetrating steel pipe was evaluated more than 637 kN, and the shaft resistance corresponding to 81~86% of each applied load was mobilized with only a small portion of the base resistance acting. And it was also evaluated that the unit skin friction was mobilized to maximum value after two months.

A Geophysical Survey of an Iron Mine Site (철광산 지역에서의 물리탐사 기술 적용 연구)

  • Kim, Kiyeon;Oh, Seokhoon
    • Journal of the Korean earth science society
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    • v.34 no.6
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    • pp.575-587
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    • 2013
  • DC electrical and electromagnetic survey was applied to evaluate the reserve of an iron mine site. We analyzed the borehole cores and the cores sampled from outcrops in order to decide which geophysical method was efficient for the evaluation of iron mine site and to understand the geological setting around the target area. Based on the core tests for specific weight, density, porosity, resistivity and P-wave velocity, showing that the magnetite could be distinguishable by the electrical property, we decided to conduct the electrical survey to investigate the irone mine site. According to previous studies, the DC electrical survey was known to have various arrays with high resolutions effective to the survey of the iron mine site. However it was also known that the skin depth is too shallow to grasp the deep structure of iron mine. To compensate the weakness of the DC electrical method, we applied the MagnetoTelluric (MT) survey. In addition, a Controlled Source MT (CSMT) method was also applied to make up the shortcoming of MT method which is weak for shallow targets. From the DC electrical and MT survey, we found a new low resistivity zone, which is believed to be a magnetite reserve beneath the old abandoned mine. Therefore, this study was confirmed for additional utility value.

The Evaluation of Bearing Resistance of Underreamed Ground Anchor through Realistic Model Experiments (실모형실험을 통한 지압형 앵커의 지압력 평가)

  • Min, Kyongnam;Lee, Jaewon;Lee, Junggwan;Lee, Dongwon;Jung, Chanmuk
    • Journal of the Korean GEO-environmental Society
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    • v.15 no.9
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    • pp.87-92
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    • 2014
  • The Ground anchor is reinforcement to resist pull-out through ground that is used supports structure. The pull-out resistance of anchor is constructed by skin friction resistance from compression borehole wall in expanded wings and bearing pressure from the ground. Especially, underreamed ground anchor is reinforcement that adopts active reinforcement to prevent deformation of ground using bearing resistance generated reaming anchorage. This study is conducted to calculate bearing resistance of underreamed ground anchor. Realistic model tests were fulfilled to determine bearing resistance of anchor, and correlate results of tests to Uniaxial Compressive Strengths (UCS) of ground models that assumed weathered rock condition in 8 case. In a comprehensive series of the tests, the bearing resistances were measured by pull-out tests. The bearing resistances derived from tests have a linear correlation with UCS. We also suggest empirical equation between bearing resistance and UCS of rocks by single linear regression analyses. In test results of this study, the bearing resistances were evaluated approximately 13 times higher than UCS of the grounds, and it is qualitatively similar to numerical values of pull-out force derived from theory.