• Proceedings of the Korea Inteligent Information System Society Conference
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• 2001.01a
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• pp.73-77
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• 2001

In this paper, we propose a virtual action system based on information agents, We call the system the MultiHammer, MultiHammer can be used for studying and analyzing online actions. MuiltiHammer provides functions of implement-ing a meta online action site and an experiment environ-ment. We have been using MultiHammer as an experiment as an experiment environment for BiddinBot. BiddingBot aims at assisting users to bid simultaneously in multiple online auctions. In order to bid simultaneously in multiple online auctions. In order to analyze the behavior of BiddngBot, we need to pur-chase a lot of items. It is hard for us to prepare a lot of fund to show usability and advantage of BiddingBot. MultiHam-mer enables us to effectively analyze the behavior of BiddingBot. MultiHammer consists of three types of agents for information collecting data storing and auctioning. Agents for information wrappers. To make agent work as wrarp-pers, we heed to realize software modules for each online action site. Implementing these modules reguires a lot of time and patience. To address this problem, we designed a support mechanism for developing the modules. Agents for data storing record the data gathered by agents for informa-tion collecting. Agents for auctioning provide online services using data recorded by agents for data storing. By recording the activities in auction sites. MultiHammer can recreate any situation and trace auction for experimentation, Users can participate in virtual using the same information in real online auctions. Users also participate in real auc-tions via wrapper agents for information collecting

• Journal of Korean Society on Water Environment
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• v.26 no.6
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• pp.895-902
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• 2010

The effect of seasonality on water quality variation is very significant. Generally, it reduce the power of the trend extraction. A parametric time-series model was used for detecting trends in historic constituent concentration data. The effect of seasonality is able to remove from time series decomposition technique. According to such statistic methode, long-term water quality trend analysis system (NTrend 1.0) was developed by Nakdong River Water Environmental Research Center. The trend analysis of BOD variation was conducted with NTrend 1.0 at Goreong and Moolkum site in Nakdong river to show the effect of water quality management action plan. Power test of trend extraction was tried each case of 'deseasonalized and deannulized' data and 'deseasonalized' data. Analysis period was from 1989 to 2006, and it's period was divided again three times, 1989~1993, 1994~1999 and 2000~2006 according to action plan period. The BOD trend was downward in Goreong site during three times and it's trend slope was very steep, and upward in Moolkum during 1989~1993, but it was turned downward during 1994~1999 and 2000~2006. It was revealed that it's very effective to reduce the concentration of BOD by water quality management action plan in that watershed. The result of power test was shown that it is high for trend extraction power in case of 'deseasonalized' data.

• The Korean Journal of Pharmacology
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• v.15 no.1_2 s.25
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• pp.45-56
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• 1979

With a view to searching after a new antihypertensive or hypotensive agents in the botanical crude plants, authors intended to reevaluate several natural products caltivated in Korea. This experiment was undertaken to compare pharmacogical actions of Machilus thunbergii Siebold et Zuccarini with those of Magnolia obovata Thunberg in anesthetized rats and in normal mice. Machilus thunbergii Sieb. et Zucc., a tree belonging to the Lauraceae family, is caltivated at Ull-ung Do, and their cortecies have been used as folk medicine mingled with those of Magnolia obovata Thunberg. These two cortecies have teen also applied in chinese medicine, it was advocated that these cortecies exerted good therapeutic effects on gastritis, convulsive abdominal pain, nausea, vomiting and urinary tract disorders. Therefore, we intended to determine the pharmacological action of two palnt of different family each other, especially their effects on blood pressure and heart rate, and also their mechanism of action were observed. We studied their action with extracts of hexane(MTHE), ether(MTEE), methanol(MTME) and water(MTWE) from Machilus thunhergii Sieb. et Zucc., and also fractionations of methanol(MOME), chloroform(MOCE) and water(MOWE) from Mapolia obovata Thunberg. The results of this experiment were as follows; 1) MTME, when intravenously administered to rats, elicited the significant hypotensive responses dependent on the administered dosage. 2) MOWE was also exhibited the hypotensive effect dependent on the treated dose. 3) Depressor effect of MTME was blocked by pretreatment with hexamethonium. 4) The hypotensive response of MOWE was blocked by pretreatment with hexamethonium or hrdralazine. 5) HTME and MOWE were also observed the anticonvulsive effect and sedative effect. These results suggested that MTME may induce the hypotensive response via central sympathetic effect, but the site of action in brain are not clarified, and the hypotensive effect of MOWE may be due to dual mechanism of central sympathetic action and direct vasodilation of blood vessel.

• Proceedings of the Ginseng society Conference
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• 1998.06a
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• pp.168-173
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• 1998

A single administration of cocaine (CO), morphine (MOR) and methamphetamine (MA) showed hyperactivity in mice. Ginseng total saponin (GTS), ginsenosides Rbl and Rgl inhibited the hyperactivity induced by the drugs. The repeated administration of CO, MOR and MA showed the development of psychological dependence showing a.: the development of conditioned place preference (CPP) in mice and the development of dopamine (DA) receptor supersensitivity showing as sensitization of the drugs. GTS and Rgl inhibited the development of not only psychological dependence but also of DA receptor supersensitivity induced by CO and MA Rbl prevented also the development of psychological dependence and DA receptor supersensitivity induced by CO and MA but not by MOR. These results suggest that the development psychological dependence induced by the drugs is closely related with the development of DA receptor supersensitivity since both phenomena were inhibited by them. Apomorphine induced climbing behavior was also inhibited by G75 but not by both of Rbl and Rgl, indicating that GTS modulate dopaminergic action at both of pre and postsynaptic sites, but both of Rbl and Rgl , only at the presynaptic site. These results suggest that active components acting at the postsynaptic site exist in GTS. In this study, it was found that GTS, ginsenosides Rbl and Rgl inhibited tyrosine hydroxylase (TH) and these components exerted inhibitory effects on both Cal' currents and $\Delta$ Cm in rat adrenal chromaffin cells. These results suggest that G75 and ginsenosides regulate catecholamine synthesis and secretion. Meanwhile, it has been demonstrated that Rbl, at high doses has more powerful inhibition of cartecholamine secretion at the presynaptic site than Rbl. Therefore, it was presumed that inhibition of morphine induced psychological dependence by Rgl, but not by Rbl results from differences in the extent of this inhibitory action on dopaminergic synthesis and secretion.

• Journal of Soil and Groundwater Environment
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• v.18 no.1
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• pp.123-128
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• 2013

Water quality and contamination of sediment is a growing concern in the Iksan stream of Korea. Heavy metal contamination and changes in the physicochemical properties of the stream were evaluated. Water and sediment samples were collected from six sites during the dry and rainy seasons; pH, DO, EC, ORP, turbidity, $PO_4$-P, $NO_3$-N and selected heavy metals (Cu, Pb, Ni, As, Zn, Cd, Hg) were measured. Results showed almost no change in pH between seasons. DO was highest at site 2 (~2.63 mg/L) in the dry season; EC (1,540 ms/m) was greatest at site 1 in both seasons. The ORP gradually increased from the dry to rainy season at most of the sites and was highest at site 5. Turbidity was highest at site 1 and gradually decreased from the dry to rainy season at all sites except site 3. $PO_4$-P ranged from a high of 1,193mg/L at site 1 to in the dry season to a low of ~1.2 mg/L at site 4. In contrast, $NO_3$-N was highest at site 3 in the rainy season (12,531 mg/L). Among the heavy metals measured, Cu and Zn concentrations were highest at all sediment sites. Cu and Zn are added to livestock feed to improve reproductive rates and can be carried to the stream with manure. Transport of sediment and heavy metals during the rainy season is the major source of stream contamination and it is important to continue monitoring and take necessary action in these areas.

• Journal of the Korean Home Economics Association
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• v.44 no.12
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• pp.189-201
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• 2006

The purpose of this study was to explore consumers' experiences in one used market site. For this purpose, in-depth interviews were conducted for the 8 consumers who were members of the used market site. In the study methodology, the grounded theory designed by Strauss and Corbin was utilized. From the analysis results, 23 subcategories and 11 categories were created. In the axial coding, the following paradigm model was proposed: 1) the casual conditions were "the pond of information" and "underground market," 2) the contextual conditions were "inconsistent behavior" and "error of communication", 3) the central phenomenon was "non-ethic behavior of seller/buyer, 4) the intervening conditions were "induction of intimacy", "use of patronage", and "creation of network", 5) the action/interaction strategy was "being shrewd", and 6) the consequence was "adaptation/non-adaptation". In selective coding, the core category was "to adapt of non-ethic behaviors through being shrewd." Based on the core category, the following four types of process of adaptation of the used market site were found: "A selfish addict," "An advanced utilitarian", "A hard philosopher," and "A cynical dropout".

• Journal of Nutrition and Health
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• v.30 no.8
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• pp.930-935
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• 1997

Fatty acid binging proteins(FABP) are distinct but related gene productes which are found in many mamalian cell types. FABP bind long chain fatty acids in vitro. However, their functions and mechanisms of action, in vivo, remain unknown . Also not known is whether all FABP function similaryly in their respective cell types. or whether different FABP have unique functions. The puropose of the present study was to assess whether different members of the FABP family exhibit different structural and function properties. A comparison was made between heart(H-FABP) and liver (L-FABP). The results show that the binding sites of both FABP are hydrophobic in nature, although the L-FABP site is more nonpolar than the H-FABP site. Additionally, the bound ligand experiences less motional constraint within the H-FABP binding site than within the L-FABP binding site. In accordance with these differences in structural properties, it was found that anthroyloxy-fatty acid transfer from H-FABP to membranes is markedly faster than from L-FABP. moreover, the mechanism of fatty acid transfer to phospholipid membranes appears to occur via transient collisional interactions between H-FABP and membranes. In contrast , transfer of fatty acid from L-FABP occurs via an aqueous diffusion mechanism.

• Journal of the Korea Safety Management & Science
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• v.17 no.4
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• pp.23-33
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• 2015

Recently, the Ministry of Employment and Labor Management is a trend to strengthen all men death rate than the accident rate. Points reduction in the accident rate change orders related to credit rating score to +2 points in his plans as part of +1 point. In addition, according to the fancy linger RISK treatment in the event of a disaster site and fiction treatment to achieve accident-free during processing the scene interspersed with equity issues have been raised. In general disaster for the problem in the first two cases occurs when abnormal process according to the disaster site manager positions dismissal policy, each division headquarters itself, interspersed disasters performance compared to processing in accordance with the refrain, processing expenses in accordance with the composition of untreated industrial accident, costs and burdens partners FTC, there is a possibility that the issues raised, such as the Ministry of Employment and Labor. In response to domestic social practices focused on the construction site practices and prevention measures should be evaluated with respect to what.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• v.31 no.5
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• pp.427-435
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• 2005

The purpose of this study was to compare clinical availability of fibrin adhesive technique with microneural suture technique. We applicated fibrin adhesive technique and microneural suture technique on cut sciatic nerve in rat and used to Compound muscle action potential of rat thigh muscle compartment and histologic finding for comparision of clinical availability. The results were as following. 1. Using latency and amplitude in Compound muscle action potential test, we compared microneural suture technique with fibrin adhesive technique for nerve regeneration effect. the means was slightly different between two method. but there's no statistically significant differences. 2. Histologic finding was similar in microneural suture technique and fibrin adhesive technique for regeneration of axon and myelin sheath in destruction site after nerve anastomosis. These results showed that the efficacy of fibrin adhesive technique was similar to that of conventional microneural suture technique. Moreover, fibrin adhesive technique is decreased operating time and imporved of incapability of accessment in conventional suture technique. Therefore this technique is a useful method to nerve anastomosis in nerve enervation and neurotransplantation.

• YAKHAK HOEJI
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• v.29 no.2
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• pp.76-89
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• 1985

The effects of ginseng saponin on the activity, phosphorylation, [$^{3}$H] ouabain binding and light scattering (disruption) of purified $Na^{+}$ ,$K^{+}$ -ATPase isolated from the outer medulla of sheep kidney were compared to those of gypsophila saponin, sodium dodecylsulfate (SDS), and Triton X-100 on the same parameters. $Na^{+}$ , $K^{+}$ -ATPase activity, phosphorylation, and [$^{3}H$] ouabain binding were inhibited by ginseng saponin (triol>total>diol), SDS, or Triton X-100, but increased by gypsophila saponin. Low doses of ginseng saponin (3.mu.g saponin/.mu.g protein) decreased phosphorylation sites and ouabain binding site concentration (Bmax) without any change of turnover number and affinity for ouabain binding which were decreased by high dose of ginseng saponin (over 10.mu.g saponin/.mu.g protein), SDS or Triton X-100. On the other hand, gypsophila saponin increased the affinity without any change of Bmax for ouabain binding. Inhibition of $Na^{+}$ ,$K^{+}$ -ATPase activity by ginseng saponin and SDS or Triton X-100 appeared before and after decrease in light scattering, respectively. These data suggest that ginseng saponins (total, diol, triol saponin) inhibit $Na^{+}$ , $K^{+}$ -ATPase activity by specific direct and general detergent action at low and high concentrations, respectively, and this inhibitory action of ginseng sapornin to $Na^{+}$ , $K^{+}$ -ATPase is not general action of all saponins.