• 대한화상학회지
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• 제24권2호
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• pp.34-37
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• 2021

A 46-year-old female presented a mass on her right lower leg where she had a burn injury due to moxibustion 10 years ago. Physical examination revealed a 3 cm sized firm nodule with tenderness. Plain radiograph was performed and it revealed well-defined calcifications. According to the history of moxibustion burn injury and the result of plain radiograph, dystrophic calcinosis cutis caused by burn injury was suspected. The patient underwent excisional biopsy using pre-,intra-, and post-operative ultrasonography (USG). There was no sign of recurrence. Herein, we report a case of a 46-year-old healthy woman who presented with single hard nodule on the right lower leg. Our case is worthwhile in two respects. First, It is first case report of dystrophic calcinosis cutis due to moxibustion burn injury. In east asian culture, moxibustion is a commonly conducted procedure and it often induces burn injury. Second, USG was used pre-, intra-, and post-operatively to assess the shape, location, and depth of the calcinosis cutis and to determine the surgical margin.

• 건축역사연구
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• 제18권6호
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• pp.103-126
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• 2009

This study aims to discover historical trends and change of form of all stupas in India with observation of field study that is as direct as possible, by classifying, analyzing, and synthesizing the stupas. Study of Indian stupa in Korea has a number of shortcomings since only introductory partial approach has been made in order to seek the origin of Korean pagoda. This study also aims to correct errors of stupa terminology in Chinese character committed by misinterpretation of Hindi language which was established by precedent Japanese scholars several decades ago. Piled-up stupas were totally destroyed by pagans, therefore their remains tell us only of structure, material, sizeand disposition. However remains of carved stone at torana and drum give us clues as to the original form of stupa and worshipping activity, as well as change to a more luxurious form. Many rock cave stupas of India show us both simple forms matching the ascetic age of early Buddhism and luxurious changes in Mahayanan era introducing us to statues of Buddha. Indians recovered the spheric form of 'anda,' a Hindi term meaning cosmic egg, from the hemispheric form of the piled-up stupa. Therefore we might discard the erratic term of 'bokbal', which means an upset vessel. Railings and parasols became main factors of stupa design. Carved railings around stupa became a sign of divinity. Serious worshipping activity made drums long or high and created multi-embossed stripes. Bases of circular drums of some cave stupas changed their shapes to rectangular or octagonal. Single parasols became multiparasols of affluent flowerlike curved stems on carved stupa. Multistoried, elongated and high parasols of Gandhara stupas are closely related to such factors as diverse changes of form in Indian subcontinent. Four-sided torana gate and ayaka column of the circular form of original stupas suggest the rectangular form of subsequent East Asian pagoda, and higher and wider base of Indian stupas became the origin of East Asian rectangular pagoda.

• 한국전기전자재료학회논문지
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• 제28권7호
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• pp.467-472
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• 2015

Thermal batteries are primary power sources for military applications requiring high reliability, robustness and long storage life. Conventional electrodes for thermal batteries are prepared by compacting powder mixtures into pellets. Separator is composed of halide mixture, such as LiCl-KCl eutectic salt, blended with MgO to immobilize the molten salt. In order to increase the power density and energy density, the resistance of electrolyte should be reduced because the resistance of electrolyte is predominant in thermal batteries. In this study, wetting behaviors and impregnation weight of molten salts as well as the micro structures of ceramic felt were investigated to be applicable to thin electrolyte. Discharge performances of single cell with the ceramic separator impregnated by molten salt were evaluated also. Zirconia felt with high porosity and large pore outperformed alumina felt in wetting characteristics and molten salt impregnation as well as discharge performances. Based on the results of this study, ceramic felt separator impregnated with molten salt have revealed as an alternative of conventional thick MgO based separator with no conspicuous sign of thermal runaway by short circuit.

• Tuberculosis and Respiratory Diseases
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• 제70권2호
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• pp.139-142
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• 2011

Background: Lung cancer is responsible for substantial proportions of cutaneous metastasis from internal malignancies. The aim of this study was to evaluate the clinical manifestations and outcomes of cutaneous metastasis in Korean lung cancer patients. Methods: On a retrospective basis, we analyzed medical records of all patients diagnosed with lung cancer from 2000 to 2006. Results: Cutaneous metastases were found in 10 of 4,385 patients. The number of cases was highest for squamous cell carcinoma. However, there was no metastasis from 754 cases of small cell carcinomas. Cutaneous metastasis was detected during staging work-up in 4 patients and it was the presenting sign of recurrence post-operative in 2 patients. Average time from the diagnosis to discovery of cutaneous metastasis was 16.3 months and median survival was 8.5 months (range, 1.8~19.1 months). Conclusion: Physicians should be acquainted with clinical manifestations and outcomes of cutaneous metastasis from lung cancer to detect new, recurrent cancer, or disease progression, and to administer appropriate and prompt management.

• 생물정신의학
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• 제2권1호
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• pp.123-130
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• 1995

A single-blind comparative study was performed using haloperidol as a reference drug in order to evaluate the efficacy and safety of nemonapride, a new benzamide derivative, in sixty-nine Korean schizophrenic patients. the total period of the study was 8 weeks, maximum dosage of nemonapride was 36mg and that of haloperidol was 24mg. Psychopathology and extrapyramidal symptoms were assessed every week or four weeks until the end of the 8th week using the PANSS, BPRS, and 4 point general side effect check list, The drug safety was assessed every week until the end of the 8th week using vital sign, body weight, EEG, EKG, and blood chemistry. In total. one patient discontinued nemonapride treatment and seven patients discontinued haloperidol treatment before the end of the study. Therefore sixty-one patients(88 %) completed the study. PNASS and BPRS scores of the two groups on the end study point demonstrated a significant improvement compared with baseline score. The number of patients who had a clinical improvement of at least 20% in baseline score was similiar in both treatment groups. The difference of Simpson's rating scale socres were significant in both groups, and mean scores were more high in the haloperidol group than in nemonapride group. No significant EKG, EEG changes were induced, no relevant change in body weight or clinical laboratory parameters were observed in the sixty-one patients during 8 weeks and no Significant difference in the both groups. From these results, nemonapride is considered to be a clinically useful drug having a wide range of antipsychotic effect in schzophrenic patients.

• Current Research on Agriculture and Life Sciences
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• 제15권
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• pp.1-5
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• 1997

벼의 유묘기 저온처리하에 나타나는 chlorosis현상의 유전양식을 규명하기 위하여 실험한 결과를 요약하면 다음과 같다. 벼 21 공시품종 유묘기 저온 ($18^{\circ}C$)처리에서 chlorosis가 나타나는 품종은 통일형인 "밀양23호"와 인디카형인 "IR 36", "Dular"로 3품종이었고, 모든 자포니카형 품종에서는 chlorosis가 나타나지 않았다. 저온처리하의 엽록소 함량 감소는 품종군과 재배종간에 다양한 차이를 나타내었다. Dular와 Toyohatamochi가 교배된 $F_2$ 집단에서 저온처리에 의해 나타나는 제 3엽의 chlorosis 현상에 대한 분리비는 정상 개체와 chlorosis 개체가 3 : 1의 이론적 분리비 적합하였다. 이결과로 벼의 유묘기 chlorosis의 유전은 단순열성 유전자에 의해 지배 되는 것으로 분석되었다.

• 대한한의학원전학회지
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• 제26권4호
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• pp.267-280
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• 2013

Objective : One of the unique syndromes in Asian traditional medicine named 'heat entering the blood chamber(熱入血室, HEBC)' first appeared in Shanghanlun(傷寒論) and Jinguiyaolue(金匱要略) written by Zhangzhongjing(張仲景) who is the most famous doctor in ancient China. Method : Through comparison between Huangdineijing(黃帝內經), Shanghanlun(傷寒論), Jinguiyaolue(金匱要略) and other medical texts, the correct meaning, causes and mechanisms of HEBC can be analysed and organized to suggest new view of HEBC in modern society. Result : This syndrome is usually occurred in women during catching cold and menstruation, accompanying alternation of chillness and fever, pseudo-malaria, delirium, raveled chest(結胸), uterine hemorrhage, etc. The main sign of this syndrome, delirium belongs to the category of liver disease and fever in Huangdineijing(黃帝內經) which is a document more early published than Shanghanlun. Although there are still many other comprehensions about what blood chamber is, it could be the same as uterus according to Huangdineijing, it is relevant to the control of menstruation and emotions, and the function of liver and thoroughfare vessel(衝脈). Conclusion : HEBC is a syndrome exclusive to women, caused by their unique physical and psychological characteristics. It's beginning can be found in Huangdineijing, and by Shanghanlun and Jinguiyaolue, its concept as a single disease pattern becomes established. In other words, HEBC is a complex disease related to menstruation and its related hormonal dysfunctions, closely related to PMS, menopausal syndrome of today. Physical symptoms accompanied by psychological anxiety and fear is characteristic of this condition. Therefore gynecological approaches as well as socio-cultural issues related to women in modern society must be adopted when dealing with HEBC.

• 대한한의학방제학회지
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• 제13권1호
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• pp.123-143
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• 2005

Objective : This study was carried out to evaluate the liver toxicities of Wild Aconiti Tuber decoction. Methods : The amounts of aconitine in the methanol extract of Wild Aconiti Tuber was measured by HPLC. Safeties was studied by LD50 in mice. Liver toxicities were evaluated histologically and by CBC, blood chemistry after 2 weeks of 0.4g/kg/day clinical dosage oral administrations in rat. Results : 1. The amounts of aconitine in the methanol extract of Wild Aconiti Tuber is $1.697{\pm}0.052mg/g$. But aconitine was not detected in the water decoction of Wild Aconiti Tuber. 2. To evaluate LD50 and safeties of Wild Aconiti Tuber decoction, ICR mice were given high dose of 2, 5, 10g/kg for single time and were observed for 2 weeks. There were no dead animal and abnormal clinical sign and no abnormalities at the autopsy. So, LD50 was admitted to higher than 10g/kg. 3. After 2 weeks of 0.4g/kg/day clinical dosage oral administrations in rat, there was no significant change in the CBC and blood chemistry. 4. In the liver tissues of clinical dosage, mitotic figures, apoptosis and individual cell death were observed, but clear liver toxicities like fatty liver or necrosis were not observed. the liver tissues of high dose in mice, hydropic changes were getting severe as dose grows. Conclusions : According to the results, though aconitine was not detected in the Wild Aconiti Tuber decoction, 0.4g/kg/day 2 weeks p. o (clinical dosage) group showed weak changes in the liver tissues and high dose group showed liver toxicities like hydropic changes.

• 인터넷정보학회논문지
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• 제13권6호
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• pp.55-62
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• 2012

그리드 환경에서 그리드 서비스를 웹 인터페이스 및 웹 서비스로 제공하기 위해 웹 표준 기술에 기반을 둔 그리드-웹 애플리케이션이 증가하고 있다. 그러나 웹 표준 보안 구조에서 위임 인증 방법의 부재로 웹 애플리케이션에 그리드 보안 시스템 GSI를 통합하는 것은 매우 어렵다. 이를 해결하기 위해서는 온라인 자격증명 저장 서비스를 이용하여 웹 애플리케이션에서 그리드 자격증명을 사용할 수 있도록 해야 한다. 본 논문에서는 그리드-웹 애플리케이션과 사용자 간의 상호 신뢰를 전제로 하는 온라인 자격증명 저장 서비스인 MyProxy를 사용하는 방법의 문제점을 분석하고, 상호 신뢰를 바탕으로 하지 않는 그리드 자격증명 위임 서비스를 제안한다. 이 서비스의 자격증명 교환 프로토콜은 OAuth에 X.509 인증 위임 절차를 추가한 것이다. 이 위임 서비스는 그리드-웹 애플리케이션에게 단일 로그온을 제공하고, 하나 이상의 그리드 자격증명을 위임하고 획득할 수 있는 보안 방법을 제공한다.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제19권1호
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• pp.55-60
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• 1997

Langerhans Cell Histiocytosis(Idiopathic Histiocytosis, Histiocytosis-X) is most often found in children and young adults, and cell proliferation with specific phenotype shows ultrastructural and immunohistochemical similarities with Langerhans Cells that normally exist in epithelium and mucosa. This disease occurs as single or multiple lesions in skull, ribs, vertebrae, mandible and long bones, and when it involves mandible, clinical sign and symptoms such as bone swelling and pain are noticed. When it involves alveolar bone, severe tooth mobility as well as gigival inflammation, proliferation, and ulceration are commonly found, and so it is not easy to differentiate it from general inflammatory diseases. Any local lesion at the tooth apex on the x-ray view needs to be differentiated from inflammatory disease, and multiple lesions from multiple ostoeoma and chronic multifocal osteomyelitis. This case is LCH in 51-year-old male patient ; this is a rare case, for the patient belongs to an age group with very low incidence rate of the disease. although three-timed biopsy tests and longterm observation at two university hospitals, it was misdiagnosed as multifocal osteomyelitis.