• Safety and Health at Work
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• 제10권4호
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• pp.420-427
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• 2019

Introduction: To prevent and manage the societal and economic burden of occupational diseases (ODs), countries should develop strong prevention policies, health surveillance and registry systems. This study aims to contribute to the improvement of OD surveillance at national level as well as to identify priority actions in Turkey. Methods: The history and current status of occupational health studies were considered from the perspective of OD surveillance. Interpretative research was done through literature review on occupational health at national, regional and international level. Analyses were focused on countries' experiences in policy development and practice, roles and responsibilities of institutions, multidisciplinary and intersectoral collaboration. OD surveillance models of Turkey, Belgium and the Netherlands were examined through exchange visits. Face-to-face interviews were conducted to explore the peculiarities of legislative and institutional structures, the best and worst practices, and approach principles. Results: Some countries are more focused on exploring OD trends through effective and cost-efficient researches, with particular attention to new and emerging ODs. Other countries try to reach every single case of OD for compensation and rehabilitation. Each practice has advantages and shortcomings, but they are not mutually exclusive, and thus an effective combination is possible. Conclusion: Effective surveillance and registry approaches play a key role in the prevention of ODs. A well-designed system enables monitoring and assessment of OD prevalence and trends, and adoption of preventive measures while improving the effectiveness of redressing and compensation. A robust surveillance does not only provide protection of workers' health but also advances prevention of economic losses.

• 한국수소및신에너지학회논문집
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• 제26권4호
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• pp.324-330
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• 2015

The electrolyte flow rates of vanadium redox flow battery play very important role in terms of ion transfer to electrolyte, kinetics and pump efficiency in system. In this paper a vanadium redox flow battery single cell was tested to suggest the optimization criteria of electrolyte flow rates on the efficiencies. The compared electrolyte circulation flow rates in this experimental work were 15, 30 and 45 mL/min. The charge/discharge characteristics of the flow rate of 30 mL/min was the best out of all flow rates in terms of charging and discharging time. The current efficiencies, voltage efficiencies and energy efficiencies at the flow rate of 30 mL/min were the best. The IR losses obtained at thd current density of $40mA/cm^2$, at the flow rates of 15, 30 and 45 mL/min were 0.085 V, 0.042 V and 0.115 V, respectively. The charge efficiencies at the current density of $40mA/cm^2$ were 96.42%, 96.45% and 96.29% for the electrolyte flow rates of 15, 30 and 45 mL/min, respectively. The voltge efficiencies at the current density of $40mA/cm^2$ were 77.34%, 80.62% and 76.10% for the electrolyte flow rates of 15, 30 and 45 mL/min, respectively. Finally, the energy efficiencies at the current density of $40mA/cm^2$ were 74.57%, 77.76% and 73.27% for the electrolyte flow rates of 15, 30 and 45 mL/min, respectively. The optimum flow rates of electrolytes were 20 mL/min in most of operating variables of vanadium redox flow battery.

• Asian Pacific Journal of Cancer Prevention
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• 제16권14호
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• pp.5647-5654
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• 2015

Gall bladder cancer (GBC) is a gastro-intestinal cancer with high prevalence among north Indian women. Platelet derived growth factor-B (PDGFB) and human epidermal growth factor receptor-2 (HER2) may play roles in the etiology of GBC through the inflammation-hyperplasia-dysplasia-carcinoma pathway. To study the association of PDGFB and HER2 polymorphisms with risk of GBC, 200 cases and 300 controls were considered. PDGFB +286A>G and +1135A>C polymorphisms were investigated with an amplification refractory mutation system and the HER2 $Ile^{655}Val$ polymorphism by restriction fragment length polymorphism. Significant risk associations for PDGFB +286 GG (OR=5.25) and PDGFB +1135 CC (OR=3.19) genotypes were observed for GBC. Gender wise stratification revealed susceptibility for recessive models of PDGFB +1135A>C (OR=3.00) and HER2 $Ile^{655}Val$ (OR=2.52) polymorphisms among female GBC cases. GBC cases with gall stones were predisposed to homozygous +286 GG and +1135 CC genotypes. Significant risk associations were found for ACIle (OR=1.48), GAVal (OR=1.70), GAIle (OR=2.00) haplotypes with GBC cases and GCIle haplotype with female GBC cases (OR=10.37, P=<0.0001). Pair-wise linkage disequilibrium revealed negative associations among variant alleles. On multi-dimensional reduction analysis, a three factor model revealed significant gene-gene interaction for PDGFB +286A>G, PDGFB +1135A>C and HER2 Ile165Val SNPs with GBC. Protein-protein interaction showed significant association of PDGFB and HER2 with the epidermal growth factor receptor signaling pathway.

• Asian-Australasian Journal of Animal Sciences
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• 제17권1호
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• pp.33-38
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• 2004

This study was aimed at testing the gene expression of antioxidant enzymes and apoptosis genes for in vitro culture in porcine embryos produced by in vitro maturation/in vitro fertilization (IVM/IVF). Pocine preimplantation embryos obtainted from IVM/IVF can be successfully culture in vitro, but they are delayed or stop to develop at specific developmental stage. Many factors such as reactive oxygen species and apoptosis in an IVM/IVF system followed by in vitro culture influence the rate of production of viable blastocysts. Porcine embryos derived from IVM/IVF were cultured in the atmosphere of 5% $CO_2$ and 20% $O_2$ at $38.5^{\circ}C$ in NCSU23 medium. The patterns of gene expression for antioxidant enzymes and apoptosis genes during in vitro culture in pocine IVM/IVF embryos were examined by the modified semi-quantitative single cell reverse transcriptase-polymerase chain reaction (RT-PCR). Porcine embryos produced by in vitro procedures were expressed mRNAs for CuZn-SOD, GAPDH and GPX, whereas transcripts for Mn-SOD and catalase were not detected at any developmental stages. Expression of caspase-3 mRNA was detected at 2 cell, 8 cell 16 cell and blastocyst, but p53 mRNA was not detected at any stages. The fas transcripts was only detected in blastocyst stage. These results suggest that various antioxidant enzymes and apoptosis genes play crucial roles in vitro culture of porcine IVM/IVF embryos.

• Journal of Communications and Networks
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• 제14권6호
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• pp.640-652
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• 2012

Many studies have investigated the smart grid architecture and communication models in the past few years. However, the communication model and architecture for a smart grid still remain unclear. Today's electric power distribution is very complex and maladapted because of the lack of efficient and cost-effective energy generation, distribution, and consumption management systems. A wireless smart grid communication system can play an important role in achieving these goals. In this paper, we describe a smart grid communication architecture in which we merge customers and distributors into a single domain. In the proposed architecture, all the home area networks, neighborhood area networks, and local electrical equipment form a local wireless mesh network (LWMN). Each device or meter can act as a source, router, or relay. The data generated in any node (device/meter) reaches the data collector via other nodes. The data collector transmits this data via the access point of a wide area network (WAN). Finally, data is transferred to the service provider or to the control center of the smart grid. We propose a wireless cooperative communication model for the LWMN.We deploy a limited number of smart relays to improve the performance of the network. A novel relay selection mechanism is also proposed to reduce the relay selection overhead. Simulation results show that our cooperative smart grid (coopSG) communication model improves the end-to-end packet delivery latency, throughput, and energy efficiency over both the Wang et al. and Niyato et al. models.

• 디지털융복합연구
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• 제14권3호
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• pp.35-43
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• 2016

우리사회를 둘러싸고 있는 대내외적인 환경변화는 우리 정부로 하여금 여러 가지 난제들을 해결하도록 압박을 하고 있다. 이러한 난제들은 대개 어느 한 부처 혹은 어느 특정기관만이 해결할 수 없는 다부처관련 혹은 여러 기관에 걸친 문제들일 가능성이 매우 높다. 따라서 정부의 문제해결 능력을 높이기위해서는 무엇보다도 협업이 문제 해결을 위한 필수적인 전략이라고 할 수 있다. 본 연구에서는 우리사회에서 많은 논란거리가 되어왔으나 여러 부처에 관련되어 있어 해결이 쉽지 않았던 난제들을 각고의 노력 끝에 해결한 지방자치단체의 사례를 분석하여 협업을 성공적으로 이끄는데 필요한 요인들이 무엇인지에 대해서 고찰해 보았다. 우선, 협업 및 협업의 유형에 대한 이론적 검토를 하였다. 둘째, 협업의 사례를 고찰하기 위해 관련 공무원들을 대상으로 인터뷰를 수행하고 그 결과를 분석하였다. 끝으로 정부부문내에서 협업을 촉진하기 위한 전략적 방안에 대하여 논의하였다. 분석결과 협업을 유도하기 위해서는 협업의 공동 목표를 공유해야 하며, 협업을 유도할 인센티브, 지원제도 등의 요인들이 매우 중요함을 밝혀냈다.

• 한국식품영양과학회지
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• 제26권6호
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• pp.1173-1180
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• 1997

Hepatotoxicity of caffeine and acetaminophen was investigated in this study. Special attention was paid to the effect of vitamins on the reduction of hepatotoxicity caused by the chemicals. Rat hepaocytes isolated by two-step perfusion method were cultured in two differents methods-suspension, monolayer cultures-, and exposed to caffeine and/or acetaminophen for 24hrs. Caffeine or acetaminophen exhibited no significant hepatotoxicity in terms of intracellular glutathione(GSH) level and lipid peroxidation(MDA), but GSH level was significantly decreased after administrated acetaminophen, and the toxicity caused by the chemicals showed a dose-dependent manner. The synergistic effect of caffeine and acetaminophen was observed when both caffeine and acetaminophen were supplemented to culture medium. At the concentration 1mM, caffeine enhanced the intracellular GSH depletion and MDA formation by 63% and 64%, respectively, compared to single supplementation of 10mM acetaminophen in culture medium. This hepatotoxicity induced membrane integrity loss was observed by lightmicroscope on the simultaneous administration of caffeine and acetaminophen in monolayer cultured hepatocytes. Co-supplementation of vitamins with caffeine/acetaminophen to culture medium results in the protection of hepatocytes from hepatotoxic attach by caffeine/acetaminophen. Especially, vitamin E was superior to vitamin C and $\beta$-carotene from the standpoints of GSH depletion and MDA formation. From this results, it has been speculated that vitamin E may play a role of antioxidant scavenging radicals produced from acetaminophen. Taken all together, in vitro culture system like monolayer culture of hepatocytes may be a useful tool for the evaluation of hepatotoxicity or protection ability of food ingredients.

• 수산해양교육연구
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• 제10권1호
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• pp.1-14
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• 1998

Transportation provides an infrastructure vital to economic growth, and it is also an integral part of production. As a port is regarded as the interface between the maritime transport and domestic transport sectors, it certainly play a key role in any economic development. Ship's delay caused by port congestion has recently has recently attracted attended with the analysis of overall operation in port. In order to analyse complicated port operation which contains large number of variable factors, queueing theory is needed to be adopted, which is applicable to a large scale transportation system in chiding ship's delay in Inchon port in relation to ship's delay problem. The overall findings are as follows ; 1. The stucture of queueing model in this port can be represented as a complex of multi-channel single-phase 2. Ship's arrival and service pattern were Poisson Input Erlangian Service. 3. The suitable formula to calculate the mean delay in this port, namely, $W_q={\frac{{\rho}}{{\lambda}(1-{\rho})}}{\frac{e{\small{N}}({\rho}{\cdot}N)}{D_{N-1}({\rho}{\cdot}N)}}$ Where, ${\lambda}$ : mean arrival rate ${\mu}$ : mean servicing rate N : number of servicing channel ${\rho}$ : utilization rate (l/Nm) $e{\small{N}}$ : the Poisson function $D_{(n-1)}$ : a function of the cumulative Poisson function 4. The utility rate is 95.0 percents in general piers, 75.39 percents in container piers, and watiting time 28.43 hours in general piers, 13.67 hours in container piers, and the length of queue is 6.17 ships in general piers, 0.93 ships in container piers, and the ship turnaround time is 107.03 hours in general piers, 51.93 hours in container piers.

• 산업융합연구
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• 제18권6호
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• pp.33-39
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• 2020

멀티스크린 영상시스템은 하나의 스크린에 상영되는 영상을 용도에 맞게 여러 화면으로 구성하여 상영할 수 있다. 관객들은 특별한 장치 없이 폭 넓은 실감 영상을 감상할 수 있어 강한 몰입감을 얻을 수 있다. 최근 멀티스크린을 이용한 실감 영상은 Screen X나 Escape와 같은 멀티 프로젝션 기술을 바탕으로 스토리와 정보 전달이 가능한 영화로 제작되고 있다. 또한, 디스플레이의 크기는 점점 대형화 추세이고 화질도 고해상도로 향상되고 있어 HD나 UHD급 디스플레이 여러대를 입체적으로 구성한 디지털 사이니지 형태로 발전을 가속하고 있으나 촬영된 영상을 사용하는 데는 화질열화로 인해 한계가 있다. 이번 연구는 1950년부터 현재까지 멀티스크린 영상의 발전사와 기술적 분석, 제작 방법에 대해 분석하고 멀티스크린을 이용한 영상 콘텐츠 상영 시 발생되는 화질 열화 최소화 방법에 대해 연구한다. 연구 결과를 바탕으로 촬영된 실사 영상은 디지털 사이니지와 같은 고해상도 영상 상영이 가능한 플랫폼에서 실감영상 구현이 가능할 것이라 기대한다.

• 한국전기전자재료학회논문지
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• 제36권3호
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• pp.226-232
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• 2023

As a potential alternative to flash memory, HfO₂/Al₂O₃ stacks appear to be a viable option as charge capture layers in charge trapping memories. The paper undertakes a review of HfO₂/Al₂O₃ stacks as charge trapping layers, with a focus on comparing the number, thickness, and post-deposition heat treatment and γ-ray and white x-ray treatment of such stacks. Compared to a single HfO₂ layer, the memory window of the 5-layered stack increased by 152.4% after O₂ annealing at ±12 V. The memory window enlarged with the increase in number of layers in the stack and the increase in the Al/Hf content in the stack. Furthermore, our comparison of the treatment of HfO₂/Al₂O₃ stacks with varying annealing temperatures revealed that an increased annealing temperature resulted in a wider storage window. The samples treated with O₂ and subjected to various γ radiation intensities displayed superior resistance. and the memory window increased to 12.6 V at ±16 V for 100 kGy radiation intensity compared to the untreated samples. It has also been established that increasing doses of white x-rays induced a greater number of deep defects. The optimization of stacking layers along with post-deposition treatment condition can play significant role in extending the memory window.