• Journal of Photoscience
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• v.9 no.2
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• pp.9-12
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• 2002

Circadian rhythms can be seen in a variety of physiological functions in insects. Light is a powerful zeitgeber not only synchronizing but also modulating the rhythm to adjust insect's temporal structure to seasonal changes in the environmental cycle. There are two general effects of the length of light phase within 24 hr light cycles on the circadian rhythms, i.e., the modulation of free-running period and the waveform. Since the photoperiodic modulation of the free-running period is induced even in the clock mutant flies, per$\^$s/, the free-running period is not fully determined genetically. In crickets, the ratio of activity (a) and rest phase (p) under the constant darkness (DD) is clearly dependent on the photoperiod under which they have been kept. When experienced the longer photoperiod it becomes smaller. The magnitude of change in a/p-ratio is dependent on the number of cycles they experienced. The neuronal activity of the optic lobe in DD shows the a/p-ratio changing with the preceding photoperiod. These data suggest that a single circadian pacemaker stores and maintains the photoperiodic information and that there is a system that accumulates the effects of single photoperiod to cause greater effects.

• Journal of the Optical Society of Korea
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• v.19 no.4
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• pp.376-381
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• 2015

Transmission characteristics of long-period fiber gratings (LPFGs) fabricated by periodically etching a conventional single-mode fiber (SMF) are investigated. After coating the SMF with photoresist, the cladding of the SMF is symmetrically and periodically removed by using a wet etching technique resulting in the formation of the LPFG. Tensile strain reinforces the coupling strength between the core and the cladding mode based on the photoelastic effect. The extinction ratio of the SMF-based LPFG at a wavelength of 1550.8 nm is measured to be -15.1 dB when the applied strain is $600{\mu}{\varepsilon}$. The ascent of ambient index shifts the resonant wavelength to shorter wavelength because of the increase of the effective refractive index of the cladding mode. The extinction ratio is diminished by increase in the ambient index because of the induction of the optical attenuation of the cladding mode. The transmission characteristics of the proposed LPFG with variations in torsion are also measured. The photoelastic effect based on torsion changes the extinction ratio and the resonant wavelength of the proposed SMF-based LPFG. The polarization-dependent loss of the LPFG is also increased by torsion because of the torsion-induced birefringence. The polarization-dependent loss of the LPFG at torsion of 8.5 rad/m is measured to be 3.9 dB.

• Journal of Soil and Groundwater Environment
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• v.15 no.1
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• pp.19-28
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• 2010

Considering six screen matrix to select an optimum remediation method for the Kunsan military base contaminated with petroleum oil, the following order was obtained: landfarming > biopile > soil washing > thermal desorption = incineration. When the landfarming method was applied for the remediation of 2,250 $m^3$ soil contaminated with petroleum oil ranging from 500 to 2,404 mg/kg as TPH, contamination level decreased below target concentration 450 mg/kg after 20~42 days depending on the initial contamination. From the evaluation of case studies of landfarming, it is suggested that ratty-truss or single-arch structure is suitable in the landfarming plant for the treatment of large-scale contaminated soil requiring long period of remediation. But, vinyl-house structure is suitable in the landfarming plant for the treatment of small-scale contaminated soil requiring short period of remediation. Therefore vinyl-house structure is recommended in the remediation of contaminated soil less than 5,000 $m^3$ requiring within 1 year of remediation period but ratty-truss or single-arch structure is recommended for the remediation of contaminated soil more than 5,000 $m^3$.

• Transactions of the Korean Society for Noise and Vibration Engineering
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• v.26 no.1
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• pp.13-19
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• 2016

The flow-excited Helmholtz resonance phenomenon was investigated numerically using Reynolds averaged Navier-Stokes approach. The fundamental cause of the Helmholtz resonance phenomenon is known as shedding of a single discrete vortex from orifice edge that travels during one period of the oscillation. In this study, serrated deflector, which is biomimetic design of the owl's feather, is used to split a single vortex into small vortices. Rectangular deflector and serrated deflector are compared with numerical results of pressure and streamline inside the cavity. Consequently, the serration breaks the shedding period of vortex core and eliminates the resonance. Also, it changes the flow pattern in according to the location of different serration height. By making inflows and outflows occur simultaneously in spanwise direction in the cavity, the period of Helmholtz resonance disappears. Comparing between rectangular deflector and serrated deflector, the serrated deflector can deal with the Helmholtz resonance more effectively.

• Journal of Korean Neurosurgical Society
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• v.39 no.3
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• pp.204-209
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• 2006

Objective : The authors retrospectively evaluate the benefits of the various pain procedures for the treatment of low back pain unresponsive to conservative management. Methods : Over a period of 2 years from May 2002 and June 2004, the authors had performed various pain procedures on 106 patients with low back pain. Epidural block, facet joint block, sacroiliac joint block, and myofascial block were included among various pain procedures. The pain improvement, period of analgesic use, and degree of satisfaction were evaluated 1 day, 4 weeks, and 6 months after injections. The outcome of pain procedures was analyzed by using a modified Macnab criteria. Results : Sixty-four patients had a single procedure with no combination and 42 patients [39.6%] received the combination of the various pain procedure. Regardless of the single or combination cases of procedure, combination of appropriate spinal level on each procedure was conducted in 104 [98.1%]. Mean follow up period was 12.2 months. Eighty-two patients [77.4%] experienced significant pain relief and overall analgesic medication was reduced in 91 patients [85.8%] at 6 months after procedure. Unfavorable results were demonstrated in 10 patients. Permanent procedural complications did not occur. Conclusion : The various pain procedures are the possible therapeutic option for low back pain unresponsive to conservative management including medication or physical therapy.

• Journal of the Korean Society of Physical Medicine
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• v.14 no.3
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• pp.63-71
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• 2019

PURPOSE: This study was examined the effects of coordinative locomotor training (CLT) on the postural imbalance and gait in children. METHODS: Four children were sampled as subjects. A single subject study (A-B-A') was conducted by measuring the following: baseline five sessions;, intervention phase, 15 sessions;, and postline (A') five sessions. The research period was eight weeks. The CLT program consisted of warming-up exercise, main exercise, and finishing exercise, and it was performed for one hour per day. A oneleg standing test (OLST) was performed determine the static balance. A functional reach test (FRT) was performed determine the reactionary balance. To determine the dynamic balance, the time up and go test (TUG) was performed. A 10m walking test (10 MWT) was performed to determine the walking ability. A statistical test was performed through descriptive statistics to present the average and standard deviation, and the variation rate was compared using a visual analysis method with graphs. RESULTS: As a result of CLT application, all four subjects improved the OLST, FRT, TUG, and 10 MWT compared to the intervention period baseline, and postline period. CONCLUSION: CLT appeared to improve the posture imbalance and gait in children.

• Journal of Oriental Neuropsychiatry
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• v.24 no.1
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• pp.131-144
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• 2013

Objectives : To provide information on the safety of ACM, we carried out a single oral dose-increasing toxicity and 4-weeks repeated oral dose determining test of ACM in beagle dogs. Methods : In a single oral dose-increasing toxicity test, beagles were treated with ACM orally increasing dose level (1,000, 2,000, 5,000 mg/㎏) at interval of 3 days. After administration, signs of toxicity were observed for two weeks. In 4-weeks repeated oral dose determinating test, beagles were treated with ACM with oral dose 500, 1,000, 2,000 mg/kg for 4 weeks. Mortality, clinical signs, body weight changes, food consumption, urinalysis, hematological and biochemical parameters, organ weights, necropsy findings, and histological findings were monitored during the study period. Results : In a single oral dose-increasing toxicity test, we found no mortality, abnormalities in clinical signs, body weight, and necropsy findings during the study period. In 4-weeks repeated oral dose determinating test, we found no mortality, abnormalities in clinical signs, body weight, food consumption, urinalysis, hematological and biological parameters, gross findings, organ weights, necropsy findings, and histopathological findings in any of the beagles tested. Conclusions : The results obtained in these studies suggest that maximum tolerated dose (MTD) of ACM in male and female beagle dogs was supposed to be over 5,000 mg/kg. For the future studies of toxicity, it is advisable that high dose and low dose are set at 2000 mg/kg and 500 mg/kg, respectively.

• Journal of Physiology & Pathology in Korean Medicine
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• v.22 no.2
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• pp.296-301
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• 2008

The purpose of this study was to examine to observe single and four weeks repeated toxicity in mice of Bangpung-galgeun-tang (BGT). We investigated to ascertain safety and toxicity of BGT, we divided into single and four weeks repeated administration test. In single test, three groups were administrated different dosages and routes (2 g/kg/i.p., 4 g/kg/i.p. and 15 g/kg/p.o.) of BGT, and in four weeks repeated test, 0.8 g/kg BGT was administrated. Control groups were administrated with only saline according to on Korean Food and Drug Administration, respectively. We observed attentively motality, abnormal clinical sign, body weight change, organ weight, AST and ALT of mice after BGT administration. During toxicity experiment period, there was no difference in body weight change, organ weight, AST and ALT among different dose groups. Death were found 3 mice from day 2 to day 3 in single test i.p. group. (2 g/kg, 4 g/kg). Several individuals of single test i.p. group were observed that decreased locomotor activity, exophthalmos, bloodshot eyes, loss of eyesight and so on in early period after administration. But there was no difference in clinical signs among p.o. group. These results indicate that BGT have inhibition effects on allergy and suggest that no observable effect level of the test orally administration was considered to be more than 2 g/kg in mice under the conditions employed in this study.

• Journal of architectural history
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• v.8 no.3 s.20
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• pp.23-38
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• 1999

The purpose of this study is to analogize the appearance of Korean Ancient Architecture in view of the Stone Remains from 3 Kingdom Period to Unificated Shilla Period. But in these period, there is no building remains but some stupas and fine arts. Especially, there are many architectural appearance and revealing signature in these Historical Stone remains. Architectural elements which are analogized by stone remains what has value as historical materials by preservation of original form from 3 Kingdom Preiod to Unificated Shilla Period are as follows : 1) Platform, the representative characteristic of Korean traditional architecture, was frame structure and accumulate structure. And circular or square footing stood a same shape column on it is put on the platform. 2) In the case of column, there used entasis column and inclined column and circular chamfer technique was applied on the top side of it. Upper side of column, capital and head pentrating tie that small bearing block was put on the center of it was joined. And longitu야nal rest(長舌) supported a cross beam. Capital and small bearing block had no bottom heel, and heel side was curved and straight. Centered bracket structure was often used, and multi bracket structure is not used yet. Inward incline technique was used. 3) Inward opening pair door which had lintel, threshold, doorjamb was usually used, Fixing stone was used for structural safety, and circular handle and lock was used for decoration. Handrail was used on the edge of wooden floor for decorative effect and safety. 4) Square rafter and circular rafter were used in the same period and so did flying rafter. Double eaves and single eave were used in the same period but, single eave was usually used. In this period, square rafter was usually used. This would be studied more by comparing with Japanese wooden architecture. 5) Hipped roof was used and half-hipped roof was not used yet. In front of th hip, there are small sculpture called Jap-Sang(雜像), and windbell was hang on the end of the hip rafter. Concave roof tile, convex roof tile, round eaver tile, decorative tile at end of roof ridge were used. Lotus style was well used on the face of roof tile for decoration. From the results of this study, wooden architecture of Unificated Shilla period was simple compare to Koryo dynasty and Chosun dynasty but, it had some brilliant character. It was hard work that analogized the form of non-existent wood architecture of Ancient Korean period by restricted stone remains. But, in addition to the results of this study and research of old documentations, more study should be go on.

• Journal of Chest Surgery
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• v.20 no.4
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• pp.643-654
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• 1987

The effect of prostacyclin[PGI, ] on myocardial preservation during global ischemia was studied in the isolating working rabbit heart model. Forty hearts underwent a 15 minute period of retrograde nonworking perfusion with Krebs-Henseleit buffer solution [37*C] and were switched over to the working mode for 15 minutes. After baseline measurement of heart rate, peak aortic pressure, aortic flow, and coronary flow, all hearts were subjected to 60 minutes of ischemic arrest at 10*C induced with St. Thomas Hospital cardioplegic solution: Group I had single dose cardioplegia, Croup II double dose, Croup III oxygenated double dose, and Group IV single dose with PCI, infusion [10ng/min./gm heart weight]. Hearts were then revived with 15 minute period of nonworking reperfusion at normothermia, followed by 30 minutes of working perfusion. Repeat measurements of cardiac function were obtained and expressed as a percent of the preischemic baseline values. Oxygen content of arterial perfusate and coronary effluent was measured by designed time interval. Leakage of creatine kinase was determined during post-ischemic reperfusion period. Finally wet hearts were weighed and placed in 120*C oven for 36 hours for measurement of dry weight. In the PGI, treated group [IV], heart rate increased consistently throughout the period of reperfusion from 100*5.0% [p<0.001] to 107*6.2% [p<0.001]. The percent recovery of aortic flow showed 95*5.7% [p<0.001] at the first 3 minute and full recovery through the subsequent time. Coronary flow was augmented significantly in the 3 minute [96*6.2%, p<0.001] and then sustained above baseline values. Among the Croup I, II, and III, all hemodynamic values were significantly below preischemic levels. PGI2 relatively increased oxygen delivery [1.22*0.19ml/min, p<0.001] and myocardial oxygen consumption [0.90*0.13ml/min, p<0.001] during reperfusion period. Leakage of creatine kinase in the PGI2 group was 9.3*1.58IU/15min [p<0.001]. This was significantly lower than Group I [33.0*2.68 IU/15min]. The water content of PCI2 treated hearts [81*0.9%, p<0.001] was also lower than the other groups.