• 응용통계연구
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• 제21권2호
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• pp.341-353
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• 2008

본 연구에서는 이변량 음이항 분포에서 과대산포와 "내재적 상"의 존재유무에 대한 가설검정 문제를 다루었다. 과대산포에 대한 스코어 검정의 표준정규분포 근사는 명목 유의수준을 과소추정한 반면 "내재적 상"에 대한 스코어 검정은 명목유의수준을 과대 추정하고 있음을 보였다. 본 연구에서는 이와 같은 스코어 검정의 표준정규분포 근사의 문제점을 해결하기 위하여 붓스트랩 방법을 제안하였다. 스코어 검정에 대한 붓스트랩 방법은 두 검정에서 명목유의수준을 제대로 유지하고 검정력도 높게 나타나 스코어 검정의 표준정규분포 근사에 존재하는 문제를 해결하는 효율적인 대안으로 판단된다.

• Asian Pacific Journal of Cancer Prevention
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• 제13권7호
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• pp.3455-3460
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• 2012

Objectives: To report the prevalence of atypical squamous cells of undetermined significance and atypical squamous cells-cannot exclude high squamous intraepithelial lesions and to determine the possible association of Pap test results with high-risk human papillomavirus and high squamous intraepithelial lesions in women from Duhok, Iraq. Design: A prospective, observational study was conducted between January 2005 and December 2011. Overall, 596 women with a cervicovaginal Pap test showing atypical squamous cells of undetermined significance and 93 atypical squamous cells-cannot exclude high squamous intraepithelial lesion for whom pathologic follow-up was available were studied. Follow-up consisted of repeat cytology, colposcopy and histology. High risk human papillomavirus DNA testing was performed on exfoliated cervical cells from 106 women, using conventional PCR after at least 36 months from the initial Pap smear. Results: Significantly high proportions of both atypical squamous cells of undetermined significance (87.9%) and atypical squamous cells-cannot exclude high squamous intraepithelial lesion (62.4%) demonstrated no significant lesion on subsequent follow up. Low squamous intraepithelial lesions were observed in 1.7% of cases of atypical squamous cells of undetermined significance and in 5.4% of atypical squamous cells-cannot exclude high squamous intraepithelial lesion. High squamous intraepithelial lesion was demonstrated in 0.8% and 16.1% respectively. In the latter there was also one case of invasive carcinoma. High-risk HPV DNA was demonstrated in 40% of atypical squamous cells of undetermined significance and 57.1% of atypical squamous cells-cannot exclude high squamous intraepithelial lesions. Conclusions: Since both atypical squamous cells of undetermined significance and atypical squamous cells-cannot exclude high squamous intraepithelial lesion identify patients who are at an increased risk for the development of high squamous intraepithelial lesions and a considerable percentage harbor high risk-HPV, both should be retained as diagnostic categories and patients warrant a diligent follow up and testing for high risk-HPV DNA. Colposcopic evaluation and biopsy, when indicated, are a must.

• 한국컴퓨터산업학회논문지
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• 제3권7호
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• pp.837-844
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• 2002

소프트웨어 개발 과정에서 시스템 내에 잔존하는 결함을 발견하거나 수정하기 위해 테스트를 실시한다. 테스트 단계에서 결함을 발견하고 소프트웨어 신뢰성을 평가할 수 있다. 수리적으로 신뢰성을 평가할 수 있는 모델이 소프트웨어 신뢰도 성장 모델이다. 이 모델의 대부분은 결함의 형태가 하나이고 결함율은 일정하다라는 가정에서 진행되고 있다. 본 연구에서는 테스트 단계에서 발견되는 결함이 일정하지 않다라는 관점에서 새로운 모델을 제안하고 결함 데이터를 적용해보았다. 또한 기존의 모델과 비교 및 분석하여 타당성을 증명하였다.

• Journal of Genetic Medicine
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• 제15권1호
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• pp.1-7
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• 2018

Sonographic findings with little or no pathological significance, known as soft markers, are often found in aneuploidy fetuses. After normal screening for the aneuploidy in first trimester, there are no uniform recommendations regarding when to disregard or put on clinical significance in isolated soft markers. Associations between some soft markers and adverse pregnancy outcomes including intrauterine fetal death, preterm birth, fetal growth restriction, and congenital infection have been reported in euploidy fetuses. The present article aims to review recent literatures about the clinical significance of soft markers after normal first trimester combined screening or noninvasive prenatal testing, and propose a simple clinical summary for management of specific soft markers in pregnancies.

• Communications for Statistical Applications and Methods
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• 제9권3호
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• pp.725-732
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• 2002

P-values are often perceived as measurements of degree of compatibility between the current data and the hypothesized model. In this paper, a new concept of Bayesian p-values is proposed and studied under the non-informative prior distributions, which can be thought as the Bayesian counterparts of the classical p-values in the sense of using the concept of significance level. The performances of the proposed Bayesian p-values are compared with those of the classical p-values through several examples.

• Communications for Statistical Applications and Methods
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• 제14권2호
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• pp.443-457
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• 2007

This paper deals with the problem of testing the existence of change in mean and estimating the change-point using nonparametric bootstrap technique. A test statistic using Gombay and Horvath (1990)'s functional form is applied to derive a test statistic and nonparametric change-point estimator with bootstrapping idea. Achieved significance level of the test is calculated for the proposed test to show the evidence against the null hypothesis. MSE and percentiles of the bootstrap change-point estimators are given to show the distribution of the proposed estimator in simulation.

• Journal of the Korean Statistical Society
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• 제25권3호
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• pp.419-432
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• 1996

When interactions are not present in a three-way layout, the lim-iting null distribution of the F statistic for testing main effects when applied to the rank-score transformed data is the same as the limiting null distribution of the usual F statistic when applied to the normal data. The simulation results exhibit that the rank transform test is robust with respect to significance level and powerful for testing main effects in a three-way factorial experiment.

• Journal of Acupuncture Research
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• 제26권5호
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• pp.11-17
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• 2009

Objectives : The objectives of this study were to examine the specificity and the sensitivity of tenderness testing on the ear about the postpartum breast pain, and to improve the efficacy of the tenderness test. Methods : Thirty women who visited in the hospital for recuperating 2-14 days after childbirth participated in this study. They answered the questionnaire of the severity of breast pain and their auricular acupuncture points were tested by a long metal probe with round tip 1.1mm in diameter. We analyzed the relationship between auricular tenderness testing on mammary gland zone[CW6] and postpartum breast pain with validity and significance as grouping 8 diagnosis methods. Results : When we consider above 'moderate pain' or 'severe pain' in the auricular tenderness testing as a positive sign, and above 'evere pain' or 'very severe pain' in the self-reported breast pain score as a positive symptom, the diagnostic efficacy was highest. The sensitivity for tenderness testing was 0.62-0.75, and the specificity was 0.64-0.72, and the sensitivity and the specificity in the contralateral ear were a little higher than in the ipsilateral ear. Conclusions : These results suggest that auricular tenderness testing can be objectified clinically and be used in diagnosis.

• 한국지능시스템학회:학술대회논문집
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• 한국퍼지및지능시스템학회 2007년도 춘계학술대회 학술발표 논문집 제17권 제1호
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• pp.225-229
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• 2007

We propose some properties of fuzzy p-value and fuzzy significance level to the fuzzy hypotheses testing for vague response data with reflected correlation in survey research, Appling the principle of agreement index, we suggest the methods for fuzzy hypothesis testing by fuzzy rejection region.

• 한국지능시스템학회논문지
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• 제17권5호
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• pp.614-618
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• 2007

통계조사에서 상관성이 반영된 애매한 응답 데이터가 주어졌을 때, 이 데이터를 퍼지화 하여 가설검정을 하는 방법으로서 퍼지 p-값과 퍼지 신뢰수준의 몇 가지 특성을 제시하고, agreement index의 원리를 이용하여 퍼지 기각역에 의한 퍼지 가설검정 방법을 제안한다.