• 제목/요약/키워드: side-effect

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가스 하이드레이트 지층 모델의 탄성파 진폭 및 주파수 특성 (Seismic Amplitude and Frequency Characteristics of Gas hydrate Bearing Geologic Model)

  • 신성렬;이상철;박근필;이호영;유동근;김영준
    • 지구물리와물리탐사
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    • 제11권2호
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    • pp.116-126
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    • 2008
  • 가스 하이드레이트의 탐사에서 탄성파 진폭과 주파수 특성은 가스 하이드레이트의 부존 여부에 대한 매우 중요한 판단 근거이다. 본 연구에서 탄성파 진폭특성은 탄성파 수치모델링 기법을 이용하여 음원 주파수 및 산란체의 크기에 따른 변화 양상을 파악하고자 하였다. 일반적으로 진폭에 큰 영향을 미치는 산란은 음원의 주파수 제곱에 비례하고 산란 이상체의 체적에 비례한다. 음원의 주파수가 높아질수록 가스 하이드레이트 지층에서의 산란이 심하여 BSR이 잘 나타나지 않는 반면 음원의 주파수가 낮아질수록 가스 하이드레이트 지층의 진폭공백대 특성이 잘 나타나고 또한 하부의 BSR이 보다 뚜렷히 보이나 해상도가 낮아지게 된다. 가스 하이드레이트 지층 하부의 Free-Gas층을 통과한 반사파는 고주파수 성분이 감쇠되어 저주파수 성분이 우세해지고, Free-Gas로 인하여 나타나는 BSR의 진폭은 극성역전현상이 발생되며 이것은 가스 하이드레이트 지층의 존재와 분포를 판단하는 중요한 인자가 된다. 탄성파 주파수 특성 분석은 Wavelet Transform을 이용하여 시간에 따른 탄성파동의 주파수 변화를 관찰하는 방법을 사용하였다. 탄성파 모형 실험 자료에 대하여 적용한 결과 Free-Gas층에 대비되는 공기층을 통과하여 반사된 탄성파의 주파수는 고주파수 성분이 상당히 감쇠되었음을 관찰할 수 있었다.

NAND 플래시 메모리 기반 B+ 트리에서 페이지 매핑 로그를 이용한 색인 관리 기법 (Index Management Method using Page Mapping Log in B+-Tree based on NAND Flash Memory)

  • 김선환;곽종욱
    • 한국컴퓨터정보학회논문지
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    • 제20권5호
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    • pp.1-12
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    • 2015
  • 낸드 플래시 메모리는 저전력, 빠른 접근 속도, 저렴한 가격 등의 특징을 가지고 있어 저장장치로 널리 사용되고 있다. 하지만 낸드 플래시 메모리는 제자리 덮어쓰기가 지원되지 않아 기존의 하드 디스크 기반 응용 프로그램을 구동하기 위해서는 FTL(Flash Translation Layer)이 필요하다. FTL은 주소 매핑, 가비지 컬렉션, 마모도 균등화 작업 등을 포함하고 있어 저사양 임베디드 장치에 구현하기에는 메모리와 연산에 대한 비용이 많이 든다. 그래서 이런 장치들을 위해 낸드 플래시 메모리에 최적화된 색인 자료구조들이 연구되고 있다. 연구된 방법들은 쓰기에 소요되는 시간을 줄여 성능을 향상시켰지만 레코드 탐색에 소요되는 시간이 증가된다는 단점을 가지고 있다. 레코드 탐색시간을 증가시키지 않고 쓰기 횟수를 줄이기 위해 본 논문에서는 페이지 매핑 로그 테이블을 이용한 색인 관리 기법을 제안한다. 낸드 플래시 메모리의 단점인 제자리 덮어쓰기 불가로 인해 발생하는 페이지 쓰기 횟수를 줄이기 위해 매핑 로그 테이블은 B+ 트리에서 변경된 노드 페이지 주소를 저장하고 레코드 검색 시 이를 이용한다. 실험 평가를 통해 제안된 기법은 다른 기법들과 비교 시 레코드 탐색에서 발생하는 페이지 읽기 횟수를 최대 약 61% 줄였으며, 레코드 삽입에서 페이지 쓰기 횟수를 최대 약 31% 줄일 수 있었다.

임상에서 분리한 메치실린 내성 황색포도상구균에 대한 녹나무잎 추출물의 항균활성 (Synergistic Effects of Cinnamomum camphora Leaves Extract against Clinical Isolated Methicillin-resistant Staphylococcus aureus)

  • 차정단;최미래;고은실;황승미;강제란;오좌섭;박영진;정용환;전아림;최경민
    • 한국자원식물학회지
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    • 제28권1호
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    • pp.9-15
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    • 2015
  • 메치실린내성 황색포도상구균(MRSA)은 가장 중요한 지역 사회 병원성 균주의 하나로서 항생제 내성 문제가 세계적으로 대두되고 있다. 감염 치료에 대한 부작용과 내성이 적은 새로운 항생제의 개발에 많은 관심과 연구가 필요하다. Cinnamomum camphora는 제주도에서 자생하는 녹나무과의 식물이다. 민간에서는 신경 쇠약, 간질, 방광염, 신우 신염, 당뇨, 암과 당뇨병 치료제로 이용되고 있다. 본 연구에서는 80% 에탄올을 이용하여 녹나무잎을 추출물하여 임상에서 분리한 메치실린 내성 균주에 대한 항균활성을 연구하였다. 그 결과 녹나무잎 추출물에서 높은 항균활성을 관찰 할 수 있었고, 항생제와의 병용처리 녹나무잎 추출물의 MIC와 MBC의 범위는 $156-313{\mu}g/ml$$313-625{\mu}g/ml$로 판독되었고, oxacillin의 병용처리의 범위는 $1288-256{\mu}g/ml$$128-512{\mu}g/ml$, 그리고 ampicillin의 병용처리 범위는 ${\mu}g/ml$$8-128{\mu}g/ml$로 판독되었다. 녹나무잎 추출물과 항생제의 병용처리는 MRSA 항균활성에 대한 상승효과가 높게 나타났다.

Possible Causes of Paleosecular Variation and Deflection of Geomagnetic Directions Recorded by Lava Flows on the Island of Hawaii

  • Czango Baag
    • IUGG한국위원회:학술대회논문집
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    • IUGG한국위원회 2003년도 정기총회 및 학술발표회
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    • pp.20-20
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    • 2003
  • In the summers of 1997 and 1998 and in February of 2000 we made 570 measurements of the ambient geomagnetic field 120 cm above the pavement surface of State Route 130, south of Pahoa, the island of Hawaii using a three-component fluxgate magnetometer. We measured at every 15.2 m (50 feet) interval covering a distance of 6, 310 m (20, 704 ft) where both historic and pre-historic highly magnetic basalt flows underlie. We also collected 197 core samples from eight road cuts, 489 specimens of which were subject to AF demagnetizations at 5 - 10 mT level up to a maximum field of 60 mT. We observed significant inclination anomalies ranging from a minimum of $31^{\circ}$ to a maximum $40^{\circ}$ where a uniform inclination value of $36.7^{\circ}$ (International Geomagnetic Reference Field, IGRF) was expected. Since the mean of the observed inclinations is approximately $35^{\circ}$ we assume that the study area is slightly affected by the magnetic terrain effect to a systematically shallower inclinations for being located in the regionally sloping surface of the southern side of the island (Baag, et al., 1995). We observed inclination anomalies showing wider (spacial) wavelength (160 - 600 m) and higher amplitudes in the historic lava flows area than in the northern pre-historic flows. Our observations imply that preexisting inclination anomalies such as those that we observed would have been interpreted as paleosecular variation (PSV). These inclination anomalies can best be attributed to concealed underground highly magnetic dikes, channel type lava flows, on-and-off hydrothermal activities through fissure-like openings, etc. Both the within- and between-site dispersions of natural remanent magnetization (NRM) are largest (up to ${\pm}7^{\circ}$) above the flows of 1955, while the area of pre-historic flows in the northern part of the study area exhibit the smallest dispersion. Nevertheless, mean inclinations of each historic flow of 1955 and 1790 are almost identical to that of the corresponding present field, whereas mean of NRM (after AF demagnetization) inclinations for each of the four pre-historic lava flow units is twelve to thirteen degrees lower than the present field inclination. We observed three cases of very large inclination variations from within a single flow, the best fitting curves of which are linear, second and third order polynomials each from within a single flow, whereas no present field variations are observed. This phenomena can be attributed to the notion that local magnetic anomalies on the surface of an active volcano are not permanent, but are transient. Therefore we believe that local magnetic anomalies of an active volcano may be constantly modified due to on going subsurface injections and circulations of hot material and also due to wide spacial and temporal distribution of highly magnetic basaltic flows that will constantly modify the topography which will in turn modify the local ambient geomagnetic field (Baag, et al., 1995). Our observations bring into question the general reliability of PSV data inferred from volcanic rocks, because on-going various geologic and geophysical activities associated with active volcano would continuously deflect and modify the ambient geomagnetic field.

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A Combination Method of CO2-Narcosis and Cold Treatment for Breaking Diapause of Bombus ignitus and Bombus terrestris Bumblebee Queens

  • Yoon, Hyung Joo;Lee, Kyeong Yong
    • International Journal of Industrial Entomology and Biomaterials
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    • 제28권2호
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    • pp.58-65
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    • 2014
  • Bumblebees are important pollinators of crops and wildflowers. Bumblebees generally produce one generation per year. One of the key stages for year-round rearing of bumblebees is breaking diapause. To evaluate the effects of a combination method of $CO_2$-narcosis and cold treatment to break the diapause of B. ignitus and B. terrestris queens, we determined whether this method affected their ability to establish a colony after the diapause break. The diapause treatment regimes that were utilized were $CO_2$ ($CO_2$-narcosis), CT-1M (cold treatment at $5^{\circ}C$ for 1 mo), CT-1M-$CO_2$ ($CO_2$-narcosis after cold treatment for 1 mo), CT-2M-$CO_2$ ($CO_2$-narcosis after cold treatment for 2 mo), CT-2M (cold treatment for 2 mo), CT-2.5M-$CO_2$ ($CO_2$-narcosis after cold treatment for 2.5 mo) and CT-2.5M (cold treatment at $5^{\circ}C$ for 2.5 mo). In view of the effects on the colony developmental characteristics of B. ignitus queens, the most favorable diapause treatment was CT-1M-$CO_2$. A combination method of $CO_2$-narcosis and cold temperature treatment yielded better results than that of single $CO_2$-narcosis or cold temperature treatment on the colony development of diapause-broken B. ignitus queens. In the case of B. terrestris queens, we concluded that a combination method of $CO_2$ and cold temperature treatment yielded better results than that of a single cold-temperature (up to 2 mo) treatment. In conclusion, the findings of the present study indicated that the combined application of $CO_2$ and cold temperature was a favorable method for the colony development of diapause-broken B. ignitus and B. terrestris queens compared with only $CO_2$-narcosis or cold temperature treatments. A combination method of $CO_2$ and cold treatment reduced the side effect of $CO_2$-narcosis and shortened the duration of cold treatment by at least 1 mo.

고단백 저탄수화물식 프로틴바를 이용한 저칼로리 다이어트가 순응 정도에 따라 과체중 여성의 체중감량과 혈청 지질지표에 미치는 영향 (Effects of Low-Calorie Diet Including High Protein-Low Carbohydrate Protein Bar on Weight Loss and Serum Lipid Indicators in Overweight Women according to Dietary Compliance)

  • 박다솜;이현주;손숙미
    • 대한지역사회영양학회지
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    • 제24권6호
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    • pp.485-496
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    • 2019
  • Objectives: This study was conducted to investigate the effect of a 6-week low-calorie diet (LCD) program including high protein-low carbohydrate protein bar on weight loss, blood pressure, and blood lipid profile in 40 overweight women according to dietary compliance. Methods: Subjects were 62 healthy overweight women (BMI ≥ 23.0 or body fat percentage ≥ 28%), aged 20~59 yrs who were provided a high protein-low carbohydrate protein bar (each 35 g, 154 kcal, protein energy %: 28.6%, carbohydrate energy %: 38.7%) as part of dinner for 6 weeks. Forty subjects who completed the whole diet program were categorized into high compliance (HC) group (days of eating protein bar ≥ 5 weeks) or low compliance (LC) group (days < 5 weeks). Results: Energy intake significantly decreased from 1,867.5 kcal at baseline to 1,137.4 kcal at 6 weeks for the HC group and from 1,971.7 kcal to 1,362.2 kcal for the LC group, respectively. On the other hand, a significant increase in protein energy percentage was observed in each group (HC group: 3.5%, LC group: 2.2%). Both groups showed significant decreases in weight (HC group: 1.8 kg, LC group: 1.1 kg), BMI, fat mass, systolic blood pressure, total cholesterol, and LDL-cholesterol. Reduction of body fat percentage and diastolic blood pressure were only observed in the HC group. Conclusions: The inclusion of a high protein-low carbohydrate protein bar as part of a low-calorie diet for a short period can be effective to achieve weight loss and concomitantly improve blood cholesterol level without serious physiological side effects. More evident results can be achieved by eating a diet with low calorie diet including high protein-low carbohydrate protein bar for more than 5 weeks.

핀 고정 천공형 티타늄막을 이용한 수직적 체조제증대술에 관한 연구 (Exophytic bone formation using porous titanium membrane combined with pins in rabbit calvarium.)

  • 김영;권영혁;박준봉;허익;정종혁
    • Journal of Periodontal and Implant Science
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    • 제36권2호
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    • pp.273-288
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    • 2006
  • The purpose of this study was to evaluate exophytically vertical bone formation in rabbit calvaria by the concept of guided bone regeneration with a custom-made porous titanium membrane combined with bone graft materials. For this purpose, a total of 12 rabbits were used, and decorticated calvaria were created with round carbide bur to promote bleeding and blood clot formation in the wound area. Porous titanium membranes (0.5 mm in pore diameter, 10 mm in one side, 2 mm in inner height) were placed on the decorticated calvaria, fixed with metal pins and covered with full-thickness flap. Experimental group I was treated as titanium membrane only. Experimental group II, III, IV was treated as titanium membrane with BBM, titanium membrane with DFDB and titanium membrane with FDB. The animals were sacrificed at 8 and 12 weeks after surgery, and new bone formation was assessed by histomorphometric as well as statistical analysis. 1. Porous titanium membrane was biocompatable and capable of maintaining the regeneration space. 2. At 8 and 12 weeks, all groups demonstrated exophytic bone formation and there was a statistical significant difference among different groups only at 12 weeks. 3. The DFDB group revealed the most new bone formation compared to other groups (p<0.05). 4. At 12 weeks, DFDB and FDB groups showed the most significant resorption of graft materials (p<0.05). 5. The BBM was not resorbed at all until 12 weeks. 6. The fixation metal pin revealed excellent effect in peripheral sealing. On the basis of these findings, we conclude that a porous titanium membrane may be used as an augmentation membrane for guided bone regeneration, and DFDB as an effective bone forming graft material. The fixation of the membrane with pin will be helpful in GBR technique. However, further study is required to examine their efficacy in the intraoral experiments.

수용성 Periodontitis-Medical Gel이 치은염, 치주염에 미치는 영향 (A Clinical Study of the Effect of Periodontitis-Medical Gel on Human Gingivitis and Periodontitis)

  • 채중규;최재성;박지숙;서종진;최성호;조규성;김종관
    • Journal of Periodontal and Implant Science
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    • 제30권1호
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    • pp.11-27
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    • 2000
  • The purpose of this study was to evaluate the clinical effects of Dipotassium glycyrrhizinate, Allantoin, Hinokitiol, Cetylpyridinium chloride containing gel($Dentheth^{(R)}$) on periodontitis. 41 patients with sites having pocket depth of 4-6mm were selected for the study. We classified 2 groups which consisted of 21 patients in the test group(exp.) and 20 patients in the control(placebo) respectively. Following a baseline examination, plaque and calculus were removed and then the experimental gel were handed out to the patients and topical application regimens were initiated. During the 4-week experimental period, pocket depth, bleeding on probing, gingival index, plaque index as a clinical parameters were measured in the baseline, 2 weeks, 4 weeks respectively. A questionnaire was delivered to each patients in 2 weeks, 4 weeks respectively. The results were as follows : 1. Probing pocket depth showed a significant difference in the Exp. group compared with the control group in the changes from baseline to 2 weeks(p<0.05), but there was no significant difference between the groups in the changes from baseline to 4 weeks, from 2 weeks to 4 weeks(p<0.05). 2. The Exp. group showed a significant difference compared with the control group in the changes from baseline to 2 weeks, from baseline to 4 weeks, from 2 weeks to 4 weeks in bleeding on probing(p<0.05). 3. The gingival index showed a significant difference compared with the control group in the changes from baseline to 2 weeks, from baseline to 4 weeks, from 2 weeks to 4 weeks after 4 weeks use of a gel(p<0.05). 4. The plaque index showed a significant difference in the Exp. group compared with the control group in the changes from baseline to 2 weeks(p<0.05), but there was no significant difference between the groups in the changes from baseline to 4 weeks, from 2 weeks to 4 weeks(p<0.05). 5. A questionnaire was consisted of 5 kinds as to bleeding, pus discharge, pain, burning sensation, patient's satisfaction and all of the questions showed a significant difference compared with the control group in the changes from 2 weeks to 4 weeks(p<0.05). 6. During the 4-week experimental period, important side-effects were not finded out, but each groups had one patient appealed nausea or discomfort respectively. These results indicate that application of periodontitis medical gel was useful as an additional aid of mechanical treatment.

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The effect of various thread designs on the initial stability of taper implants

  • Park, Ju-Hee;Lim, Young-Jun;Kim, Myung-Joo;Kwon, Ho-Beom
    • The Journal of Advanced Prosthodontics
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    • 제1권1호
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    • pp.19-25
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    • 2009
  • STATEMENT OF PROBLEM. Primary stability at the time of implant placement is related to the level of primary bone contact. The level of bone contact with implant is affected by thread design, surgical procedure and bone quality, etc. PURPOSE. The aim of this study was to compare the initial stability of the various taper implants according to the thread designs, half of which were engaged to inferior cortical wall of type IV bone(Group 1) and the rest of which were not engaged to inferior cortical wall(Group 2) by measuring the implant stability quotient(ISQ) and the removal torque value(RTV). MATERIAL AND METHODS. In this study, 6 different implant fixtures with 10 mm length were installed. In order to simulate the sinus inferior wall of type IV bone, one side cortical bone of swine rib was removed. 6 different implants were installed in the same bone block following manufacturer s recommended procedures. Total 10 bone blocks were made for each group. The height of Group 1 bone block was 10 mm for engagement and that of group 2 was 13 mm. The initial stability was measured with ISQ value using Osstell $mentor^{(R)}$ and with removal torque using MGT50 torque gauge. RESULTS. In this study, we found the following results. 1. In Group 1 with fixtures engaged to the inferior cortical wall, there was no significant difference in RTV and ISQ value among the 6 types of implants. 2. In Group 2 with fixtures not engaged to the inferior cortical wall, there was significant difference in RTV and ISQ value among the 6 types of implants(P < .05). 3. There was significant difference in RTV and ISQ value according to whether fixtures were engaged to the inferior cortical wall or not(P < .05). 4. Under-drilling made RTV and ISQ value increase significantly in the NT implants which had lower RTV and ISQ value in Group 2(P < .05). CONCLUSIONS. Without being engaged to the inferior cortical wall fixtures had initial stability affected by implant types. Also in poor quality bone, under-drilling improved initial stability.

연안개발사업 유형에 따른 해양환경영향평가 개선방안 (Improvement for Marine Environmental Impact Assessment on the Coastal Development Project Type)

  • 김인철;전경암;김귀영;엄기혁;김영태;최보람
    • 해양환경안전학회지
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    • 제20권2호
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    • pp.157-164
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    • 2014
  • 본 연구에서는 2010년부터 2013년까지 4년간 연안개발사업에 따른 일반해역이용협의서 133건을 분석하여 사업유형별 해양환경영향평가 개선방안을 제시하였다. 침식방지사업은 정확한 침식원인 분석이 선행되어야 하고 주변 해안의 상태와 구조물 설치 시 추가적인 문제점 발생 가능성에 대해 정확히 예측해야 하며, 사업시행 후 사후모니터링을 통한 침식방지 효과를 입증하는 체계적인 시스템이 마련되어야 한다. 호안 및 해안도로 건설사업의 경우, 무분별한 해안도로의 건설은 지양하고 구조물 안정성을 충분히 검토하여야 하며 반사파 증가에 따른 해안침식의 문제점을 함께 검토해야 한다. 그리고 침수방지 사업은 평가항목에 파랑을 선정할 필요가 있고 이상 파랑의 영향을 함께 고려해야 한다. 친수공간 조성사업은 종합적이고 체계적인 공간계획이 수립되어야 하고, 자연환경을 최대한 보전하고 자연과 융화될 수 있는 개발이 될 수 있도록 검토를 강화해야 할 것이다. 아울러 연안개발사업과 관련하여 많은 문제점이 내재되어있어 법 제도적 측면에서의 지원과 함께 추후 해역별, 사업별 특성이 다양하게 반영된 추가적인 연구가 필요할 것으로 판단된다.