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The Diameter Expansion of 6H-SiC Single Crystals by the Modification of Inner Guide Tube (새로운 가이드 튜브를 통한 6H-SiC 단결정의 직경 확장에 관한 연구)

  • Son, Chang-Hyun;Choi, Jung-Woo;Lee, Gi-Sub;Hwang, Hyun-Hee;Choi, Jong-Mun;Ku, Kap-Ryeol;Lee, Won-Jae;Shin, Byoung-Chul
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.21 no.9
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    • pp.795-800
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    • 2008
  • A sublimation method using the SiC seed crystal and SiC powder as the source material is commonly adopted to grow SiC bulk single crystal. However, it has proved to be difficult to achieve the high quality crystal and the process reliability because SiC single crystal should be grown at very high temperature in closed system. The present research was focused to improve SiC crystal quality grown by PVT method through using the new inner guide tube. The new inner guide tube was designed to prevent the enlargement of polycrystalline region into single crystalline region and to enlarge the diameter of SiC single crystal. The 6H-SiC crystals were grown by conventional PVT process. The seed adhered on seed holder and the high purity SiC source materials are placed on opposite side in sealed graphite crucible surrounded by graphite insulation. The SiC bulk growth was conducted around 2300 $^{\circ}C$ of growth temperature and 50 mbar in an argon atmosphere of growth pressure. The axial thermal gradient across the SiC crystal during the growth was estimated in the range of 15${\sim}$20 $^{\circ}C$/cm.

Efficacy of Permanent Iodine-125 Seed Implants and Gemcitabine Chemotherapy in Patients with Platinum-Resistant Recurrent Ovarian Carcinoma

  • Yang, Hui;Liu, Yu-Hui;Xu, Liang;Liu, Li-Heng
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.20
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    • pp.9009-9013
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    • 2014
  • Background: The aim of this study was to explore the efficacy and adverse reactions of CT-guided radioactive 125I-seed implantation treatment combined with chemotherapy for platinum-resistant recurrent ovarian carcinoma. Materials and Methods: From September 2010 to December 2012, 23 patients with platinum-resistant recurrent ovarian carcinoma were enrolled. All the patients refused, could not bear, or were not suitable for surgery. They all had no more than 3 lesions, which were detected and could also be measured by CT. All were clarified as single-lesion or multiple-lesion groups. A total of 41 lesions underwent implantation of from 8 to 106 125I seeds (median=43). Multi-plane implanting was adopted and 125I-seeds of (0.4-0.7)mCi were placed at intervals of (0.5-1.0) cm. After implantation treatment, all patients underwent 4 cycles of chemotherapy with gemcitabine $800mg/m^2$ (days 1, 8 and 15). Results: The outcome was evaluated with CT 3 weeks and every 3 months after implantation treatment. After 6 months, the volume of 32 out of 41 lesions (78.0%) was reduced at least 30%, within which 9 lesions completely disappeared(22.0%). Complete response was observed in 7 cases (30.4%), with a partial response in 4 cases (17.4%), 4 cases stable(17.4%)and 8 cases showing progression (34.8%). The total clinical remission rate was 47.8% (11/23). The clinical remission rate was 77.8% (7/9) in the single-lesion group and 28.6% (4/14) in the multiple-lesion group with a significant difference between the two(P=0.036). The common side effects observed were mild gastrointestinal reactions. Conclusions: 125I-seed implantation combined with chemotherapy applies an effective way in the treatment of platinum-resistant recurrent ovarian epithelial carcinoma with the advantages of high local control rates, good short-term effects, little trauma and less side effects.

Phytochromes A and B: Specificity of photoperception and structure/function analysis of bilin chromophores

  • Shinomura, Tomoko;Hanzawa, Hiroko;Furuya, Masaki
    • Journal of Photoscience
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    • v.9 no.2
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    • pp.90-93
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    • 2002
  • Phytochrome A (phyA) and phytochrome B (phyB) perceive light and adapt to fluctuating circumstances by different manners in terms of effective wavelengths, required fluence and photoreversibility. Action spectra for induction of seed germination and inhibition of hypocotyl elongation using phytochrome mutants of Arabidopsis showed major difference. PhyA is the principal photoreceptor for the very low fluence responses and the far-red light-induced high irradiance responses, while phyB controls low fluence response in a red/far-red reversible mode. The structural requirement of their bilin chromophores for photosensory specificity of phyA and phyB was investigated by reconstituting holophytochromes through feeding various synthetic bilins to the following chromophore-deficient mutants: hy1, hyl/phyA and hyl/phyB mutants of Arabidopsis. We found that the vinyl side-chain of the D-ring in phytochromobilin interacts with phyA apoprotein. This interaction plays a direct role in mediating the specific photosensory function of phyA. The ethyl side-chain of the D-ring in phycocyanobilin fails to interact with phyA apoprotein, therefore, phyA specific photosensory function is not observed. In contrast, both phytochromobilin and phycocyanobilin interact with phyB apoprotein and induce phyB specific photosensory functions. Structural requirements of the apoproteins and the chromophores for the specific photoperception of phyA and phyB are discussed.

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High-frequency plant regeneration from transgenic rice expressing Arabidopsis thaliana Bax Inhibitor (AtBI-1) tissue cultures

  • Cho, A-Ra;Lee, Dong-Kil;Kim, Kyung-Min
    • Journal of Plant Biotechnology
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    • v.42 no.2
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    • pp.83-87
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    • 2015
  • Genetic transformation was affected by material of explant, age of callus, and medium of regeneration. Two rice seed cultivars (Ilpum and Baekjinju) and mediums were investigated in this study for enhancing regeneration of transgenic rice expressed AtBI-1 gene encoding the Arabidopsis thaliana Bax inhibitor. Regeneration rate of Ilpum rice transformant in gelrite of 5 and 8 g were 27.4% and 18.0%, respectively. In Baekjinju, regeneration rate of transformant was 5.4% and 4.3% in 5 and 8 g gelrite, respectively. The highest number of transformant plant in this study was regenerated from Ilpum cultivar on MS medium (30.4%) and was applied for the subsequent experiment. The callus regeneration rate of transformant were 40.7% in callus infection of up-side, it was higher regeneration then in the down-side (3.9%). The regeneration rate of callus of 25 days and 35 days were 14.7% and 38.6%, respectively. The most important application of this work is in genetic transformation of rice, particularly for improvement transgenic plant tissue culture protocol with high frequency of plant regeneration.

The Performance of Micro Fluxgate Sensor with Magnetic Core Shape (자성체 코어 형상에 따른 마이크로 플럭스게이트 센서의 검출 특성)

  • 조중희;최원열
    • Journal of the Korean Institute of Electrical and Electronic Material Engineers
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    • v.17 no.5
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    • pp.508-514
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    • 2004
  • A fluxgate magnetic sensor consists of a solenoid excitation coil, pick-up coil, and magnetic core. We presents the effect of magnetic core shape in a micromachined fluxgate sensor. To observe the performance of fluxgate sensor with magnetic core side width and gap, side width of 125 ${\mu}{\textrm}{m}$, 250 ${\mu}{\textrm}{m}$, and 500 ${\mu}{\textrm}{m}$ were designed in a rectangular-ring shaped core and the gaps of 0 ${\mu}{\textrm}{m}$, 50 ${\mu}{\textrm}{m}$, and 100 ${\mu}{\textrm}{m}$ were also fabricated in a racetrack shaped core. The solenoid coils and magnetic core were separated by benzocyclobutane(BCB) which had high insulation and good planarization characters. Copper coil patterns of 10 ${\mu}{\textrm}{m}$ width and 6${\mu}{\textrm}{m}$ thickness were electroplated on Ti(300 $\AA$) / Cu(1500 $\AA$) seed layers. 3 ${\mu}{\textrm}{m}$ thick N $i_{0.8}$F $e_{0.2.}$(permalloy) film for the magnetic core was also electroplated under 2000 gauss to induce the magnetic anisotropy. The magnetic core had the high DC effective permeability of ∼1,300 and coercive field of ∼0.1 Oe. Because the magnetic cores of 500 ${\mu}{\textrm}{m}$ side width and 0 gap had a low magnetic flux leakage, high sensitivity of ∼350 V/T were measured at excitation condition of 3 $V_{P-P}$ and 2 MHz square wave. The power consumption of ∼14 ㎽ was measured. The fabricated fluxgate sensor had the very small actual size of 3.0${\times}$1.7 $\textrm{mm}^2$. When two fluxgates were perpendicularly aligned in terrestrial field, their two-axis output signals were very useful to commercialize an electronic azimuth compass for the portable navigation system.m.m.m.

A Clinical Study to Evaluate the Efficacy and Safety of Hair Ampoules Containing Malva Verticillata Seed Extract in Subject with Alopecia (탈모 환자에서 동규자(冬葵子) 추출물을 함유하는 두피 앰플의 탈모 증상 완화 기능성 및 안전성을 평가하기 위한 임상적 연구)

  • Young-Chae Song;Bich-Euro Park;Kim Tae-Jun;Yong-Min Kim;Sang-Jun Lee;Su-Hyun Ahn;Chun-Mong Lee;Kwang-Sik Lee;Jung-No Lee;Hee-Taek Kim
    • The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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    • v.37 no.2
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    • pp.37-57
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    • 2024
  • Objectives : The purpose of this study is to evaluate the efficacy and safety of hair Ampoules with Malva Verticillata Seed Extract in alopecia patients. Methods : This 24-week clinical study enrolled 70 patients with Alopecia. A series of clinical examinations, subjects were evaluated at 0, 8, 16 and 24-week, counting of the number of hairs on the crown, and subject survey after using the Ampoules. Results : The clinical evaluation showed a significantly difference (p<0.05) after 24 weeks of product use compared to the baseline in the change in hair count in the treatment group compared to the control group within and between groups. It showed greater improvement in the treatment group than in the control group in hair count, hair thickness, and hair loss symptoms in the top of the head and forehead. No severe adverse events were observed during the clinical trial. Counclusions : This suggests that this hair ampoules containing Malva Verticillata Seed Extract could help prevent hair loss in alopecia patients without inducing side effects.

Comparative Studies of Fowl and Pigeon pox Virus Strains for the Preparation of Fowl pox Vaccine (계두예방약용(鷄痘豫防藥用) 계두독(鷄痘毒)과 구두독주(鳩痘毒株)의 비교연구(比較硏究))

  • Jeon, Yun S.;Kim, Sun J.;Jeong, Yung S.;Chung, Young S.
    • Korean Journal of Veterinary Research
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    • v.5 no.1
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    • pp.37-41
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    • 1965
  • For the preparation of an effective fowl pox vaccine, comparative studies of a number of fowl and pigeon pox virus strains were accomplished, and the following conclusions were made. 1. Anyang-Nakano strain which was nation widely used as a seed virus of fowl pox vaccine was proven its inadequacy. 2. A liquid vaccine prepared with Minnesota strain of pigeon pox virus showed its stability for 6 months and on side reaction.

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Information Hiding Application Method Using Steganography (스테가노그라피를 활용한 정보은닉 응용기법 연구)

  • Lee, Cheol;Kim, Yong-Man;Yoo, Seung-Jae
    • Convergence Security Journal
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    • v.10 no.2
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    • pp.19-26
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    • 2010
  • In this study, we try to make up for the vulnerability in steganography that it is easily revealed the hidden logo image in cover image by bit-plane extraction. For this, we apply some methods, the permutation which shift the scattered pieces of logo image to one side, bit-plane dispersion insertion method and pack-type compressor.

Problems and Their Solutions in Growing Seombadi ( Dystaenia take simana ) (섬바디의 재배상 문제점과 해결방안)

  • 허삼남
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.2 no.2
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    • pp.16-20
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    • 1981
  • To cultivate Dystaenia takesimana as a fodder crop, Its problems and solutions are summarized follows : 1. There are a wax layer and wings on the out side of seed coat of D. takesimana seeds, which seems to inhibit imbibition and cause delayed germination. 2. The root and shoot growth of D. takesimana are very poor in the early stage and weed control is quite troublesome. 3 The growth of D. takesimana is very poor the soil of low fertility and much depressed in summer. 4 . The percent germination could be increased by removing wings, soaking, high temperature treatment or by chemical scarification. 5. Compost is most effective for the growth of D. takesimana and lime dressing is desired in the soil of low pH. 6 . The seedling growth could be improved selecting and breeding the strains with better germination and root growth, at the germination and growth characteristics of D. takesimana are variable.

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Morphological characteristics of leaves and trichomes in reciprocal hybrids of Quercus dentata and Q. serrata

  • Lee, Jeong-Ho
    • Korean Journal of Plant Taxonomy
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    • v.39 no.2
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    • pp.74-79
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    • 2009
  • The morphological characteristics of leaves, trichomes, and acorns in 8- to 11-year-old reciprocal hybrids of Quercus dentata and Q. serrata were investigated. The reciprocal hybrids had obovate to obovateelliptic leaves that were smaller than those of Q. dentata but similar to Q. serrata in their leaf size, obtuse leaf apex, narrow-tipped leaf base, and shape of small to intermediate-sized serrations. The ray length of stellate hairs was intermediate between those of the parents, and the hairs showed dense growth. Long single hairs are present among the stellate hairs on the abaxial side of the leaves. Therefore, the hybrids of Q. dentata and Q. serrata could be identified by the size and shape of leaves, shape of serrations, and type of leaf trichomes.