• 제목/요약/키워드: side

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Mitochondrial Effects on the Physiological Characteristics of Lentinula edodes

  • Minseek Kim;Seong-Hyeok Yang;Hui-Gang Han;Eunbi Kim;Sinil Kim;Youn-Lee Oh;Hyeon-Su Ro
    • Mycobiology
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    • 제50권5호
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    • pp.374-381
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    • 2022
  • In the mating of filamentous basidiomycetes, dikaryotic mycelia are generated through the reciprocal movement of nuclei to a monokaryotic cytoplasm where a nucleus of compatible mating type resides, resulting in the establishment of two different dikaryotic strains having the same nuclei but different mitochondria. To better understand the role of mitochondria in mushrooms, we created four sets of dikaryotic strains of Lentinula edodes, including B2×E13 (B2 side) and B2×E13 (E13 side), B5×E13 (B5 side) and B5×E13 (E13 side), E8×H3 (E8 side) and E8×H3 (H3 side), and K3×H3 (K3 side) and K3×H3 (H3 side). The karyotypes and mitochondrial types of the dikaryotic strains were successfully identified by the A mating type markers and the mitochondrial variable length tandem repeat markers, respectively. Comparative analyses of the dikaryotic strains on the mycelial growth, substrate browning, fruiting characteristics, and mitochondrial gene expression revealed that certain mitochondria are more effective in the mycelial growth and the production of fruiting body, possibly through the activated energy metabolism. Our findings indicate that mitochondria affect the physiology of dikaryotic strains having the same nuclear information and therefore a selection strategy aimed at mitochondrial function is needed in the development of new mushroom strain.

Aerodynamic Characteristics of Neighboring Building Exposed to Twisted Wind

  • Lei Zhou;KamTim Tse;Gang Hu
    • 국제초고층학회논문집
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    • 제11권4호
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    • pp.241-263
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    • 2022
  • The conventional wind and twisted-wind effect on aerodynamic properties of neighboring buildings arranged in side-by-side and tandem systems at 2B and 5B spacings are systematically investigated by large eddy simulation. Different physical interactions between different wind profiles and neighboring buildings will be deeply understood. The neighboring-building system under two different types of wind profiles, i.e., conventional wind profile (CWP), twisted wind profiles (TWP) with the maximum twisted angle of 30°, is used to evaluate the variation of physical mechanism between wind and buildings. Aerodynamic characteristics including mean and RMS pressure coefficient, and velocity field were systematically analyzed and compared between different scenario. It was found that the distribution of mean pressure, root-mean-square x velocity and the streamline of wind flow for TWP greatly deviated from CWP, and the effect of TWP on the downstream building, was drastically different from that of CWP, such as the size of vortexes after the lower stream building being bigger when exposed to TWP, and the mean pressure distribution on the building surfaces are also different. Moreover, evidence of buildings arranged in side-by-side and tandem configurations having interchangeable properties under TWP was also discovered, that two buildings being arranged side-by-side exposed to TWP could be identified as being arranged in tandem with a different wind twist angle, or vice versa.

의약품 부작용 정보 전달의 중요성: 설문조사 기반 고찰 (Enhancing Communication on Medication Side Effects: Insights from a Survey Study)

  • 최지혜;한혜성;심미경;손현순
    • 한국임상약학회지
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    • 제34권2호
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    • pp.126-133
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    • 2024
  • Background: Medication's benefits and harms require careful management. Laws mandate pharmacists to provide essential medication details since inadequate counseling may pose risks. This study explores public expectations for pharmacist-provided side effect information to enhance safety. Methods: A self-developed questionnaire was created for participant to self-report, refined through pilot surveys with experts and laypersons. Nineteen items were categorized into four sections, using closed-ended questions. Adults over 20, having obtained prescription medications within the past year, were surveyed via convenience sampling. Data analysis employed descriptive statistics and T-tests using IBM SPSS Statistics 21 and Microsoft Excel. Results: The study involved 189 participants, with a slightly higher proportion of females (59.3%) than males (40.7%), predominantly in their 20s (45.0%) and college graduates (57.1%). Health professionals represented 76.2% of respondents. Over half visited pharmacies at least 5 times yearly for prescriptions. Indirect experience with side effects was more common (30.2%) than direct experience (17.5%). Most (82.0%) showed interest in media-reported side effect events. Satisfaction with pharmacist-provided side effect explanations was low (59.7%), but importance was high (98.9%). Preferences favored combined verbal and written explanations (65.1%), with a majority desiring explanations for common but less serious side effects (82.5%). Healthcare professionals found explanations significantly more sufficient than non-professionals did. Older individuals, those living with elderly, and frequent pharmacy visitors attributed greater importance to pharmacist-provided explanations. Conclusion: Koreans view pharmacist-provided medication side effect explanations as vital but find current services lacking. Enhancements in content and delivery methods are needed in pharmacy counseling to meet public expectations.

조립식(組立式) 탁자(卓子)의 CBA접합부(接合部) 강성(剛性)에 관(關)한 연구(硏究) (A Study on the Stiffness of CBA(Corner Block with Anchor Bolt) Joint in Knockdown Type Table Furniture)

  • 정우양;이필우
    • Journal of the Korean Wood Science and Technology
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    • 제17권2호
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    • pp.34-64
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    • 1989
  • 포장(包裝) 용적(容積) 감소에 따른 수송비(輸送費) 절감(節減) 효과(效果)가 있어 조립시(組立式) 탁자류(卓子類) 가구(家具)의 제작(製作)에 널리 쓰이는 CBA(corner block with anchor bolt) 접합방식(接合方式)은 일정기간(一定期間) 사용(使用)함에 따라 접합부위(接合部位)가 약해지고 그 결과(結果) 구조(構造)가 불안정(不安定)하게 되는 반강접합(半剛接合)(semi-rigid joint) 특유(特有)의 결점(缺點)도 지니고 있다. 따라서 본(本) 연구(硏究)에서는 CBA 접합(接合) 강도(强度)에 영향하는 주요(主要) 설계(設計) 인자(因子)로서 side rail 규격, corner block의 side rail에의 부착시(時) 보강재(補强材)의 효과(效果) 및 corner block관통 anchor bolt의 사용(使用) 수(數) 그리고 corner block의 형태등(等)의 평가(評價)를 하기 위해 22개(個)의 접합군(接合群) 별(別)로 총(總) 88개(個)의 table section 시험체(試驗體)를 제작(製作)한 후(後)그들의 강성(剛性) 계수(係數)(Z - 값) 및 유효강도(有效强度)를 수평 하중(荷重)에 의한 변형측정(變形測定) 실험(實驗)을 통해 결정(決定)한 후 설계(設計) 인자별(因子別) 효과(效果)를 비교 분석(分析)하였다. 분석결과(分析結果), side rail의 높이 증대(增大) 및 corner block 부착시(時) PVAc 수지(樹脂)의 사용효과(使用效果)가 뚜렷하여 유효강도(有效强度)의 유의적(有意的) 향상(向上)을 나타냈고 anchor bolt의 효과(效果) 역시 2개 사용시(使用時)가 1개 사용시(使用時) 보다 훨씬 큰 것으로 나타났다. 또 side rail 높이 와 anchor bolt 사용(使用) 수(數)간에는 상호작용(相互作用) 효과(效果)도 있었다. 그러나 side rail의 두께 효과(效果)는 22mm에서 25mm로 증대(增大)시켰을때 뚜렷한 상승 경향(傾向)은 보여주지 못했다. 한편 corner block의 형태는 MDF를 주재료(主材料)로 사용(使用)한 탁자(卓子) 설계시(設計時)는 두께 25mm, 높이 100mm의 side rail에 PVAc 수지(樹脂)로 보강(補强)하고 mitered corner block에 2개(個)의 anchor bolt를 관통시킨 경우가 유효강도(有效强度) 3171.7 kgf-cm로 22개의 접태군(接台群)들 중 최대치(最大値)를 나타냄으로써 miter type이 rectangular type보다 바람직한 것으로 나타났다. 결론적(結論的)으로 자재(資材)의 효과적(效果的) 이용(利用)을 통한 생산비(生産費) 절감(節減)과 동시(同時)에 구조(構造)의 안정(安定)된 강도적(强度的) 측면(側面)을 고려할 때, 두께 22mm, 높이 75mm의 MDF side rail에 mitered corner block을 PVAc 수지(樹脂)와 나사못을 이용하여 부착한 후(後) 2개(個)의 anchor bolt를 관통시키는 방법(方法)을 가장 합리적(合理的)인 MDF 사용(使用) 조립시(組立式) 탁자(卓子) 설계(設計) 방안(方案)으로 제시(提示)하는 바이다.

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저작습관에 따른 교합력과 안면골격형태의 비교연구 (A STUDY ON THE MAXIMUM BITE FORCE AND FACIAL MORPHOLOGY ACCORDING TO CHEWING SIDE PREFERENCE)

  • 정미라;손우성
    • 대한치과교정학회지
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    • 제25권3호
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    • pp.311-321
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    • 1995
  • 이상적 교합이란 치아의 교합이 저작계의 다른 부분과 기능적으로 조화를 이루고, 중심교합상태에서 양측으로 동시에 균일한 접촉을 이루는 것을 말한다. 악골의 양측을 이용한 균형된 저작은 양측의 균등한 견치유도와 기능적 능력에 의해 가능해지지만 교합간섭이나 저작계에 대한 기능적 요구의 감소로 좌우측중 어느 한쪽만을 선호하는 편측저작양상이 유도되기도 한다. 편측저작은 악골의 발육 교합 및 안면의 전체적인 형태에 이르기까지 악안면 전체에 형태적, 기능적인 부전을 초래할 잠재성을 가진 증상이나 이에 대한 연구가 많지 않다. 본 연구는 저작습관의 분포를 알아보고, 저작습관에 따른 교합력의 차이와 안면골격형태를 비교 연구할 목적으로 시도하였다. 부산대학교 치과대학 재학생 186명을 대상으로 설문지를 이용하여 저작습관에 따라 양측저작군과 편측저작군으로 나누어 저작습관의 분포를 조사하였고, 이 중 두개안면부의 성장발육에 영향을 미칠만한 질병에 이환되지 않았고 측모가 양호하며 Angle분류 I급의 교합상태를 보이면서 교정치료와 보철치료를 받은 경험이 없고 악관절 질환이 없는 자 중 양측저작자와 편측저작자 각각 25명을 선정하여 교합력계(MPM 3000)를 이용하여 최대교합력을 측정하고, 정모두부방사선규격사진을 촬영하여 안면골격형태를 비교연구하여 다음과 같은 결과를 얻었다. 1. 저작습관은 양측저작자($68\%$)가 많았으며, 편측저작자 중 $68\%$는 우측을, $32\%$는 좌측의 저작을 선호하였다. 2. 양측저작군은 좌우측의 최대교합력이 비슷하였고, 편측저작군은 저작측이 비저작측보다 교합력이 컸으며 특히 여자에서 그 차가 뚜렷하였다. 편측저작군은 양측저작군에 비해 저작측은 교합력이 컸으며, 비저작측은 작았지만 유의성은 없었다. 저작습관에 상관없이 남자가 여자보다 교합력이 컸으며 남자는 여자의 교차력의 약2배정도이었다. 남녀를 합한 경우 편측저작군의 저작측은 양측저작군의 교합력과 비슷하였으나 비저작측은 그것보다 작았다. 3. 정모두부방사선규격사진을 이용하여 안면골격형태를 비교한 결과 양측저작군의 좌우측, 편측저작군의 저작측과 비저작측간에 차이가 없었다.

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초음속 고받음각에서의 원뿔형 물체 주위의 비대칭 와류 특성 연구 (ASYMMETRIC VORTEX CHARACTERISTICS AT A CONE UNDER SUPERSONIC HIGH ANGLE OF ATTACK FLOW)

  • 박미영;노경호;박수형;이재우;변영환
    • 한국전산유체공학회지
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    • 제13권2호
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    • pp.8-13
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    • 2008
  • A supersonic viscous flow over a five-degree half-angle cone is studied computationally with three-dimensional Navier-Stokes equations. Steady asymmetric solutions show that the asymmetric flow separation is caused by convective instability. The effects of angle of attacks, Reynolds numbers, and Mach numbers have been investigated and it is found that those factors affect the generation of the side force. The side force has the maximum value at ${\alpha}=22^{\circ}$, while over ${\alpha}=22^{\circ}$, asymmetric vortex becomes transient, which results in the unsteady shedding. At the angle of attack of 22 degrees, the side force increases with Reynolds number and decreases with Mach number. The increase of the side force stops over the critical Reynolds number for the present configuration.

선로전환기용 기억쇠 단일화 개선방안 연구 (Study on the improvement of Memory-device unification for Point-switch machine)

  • 이남일;고양옥;정호형
    • 한국철도학회:학술대회논문집
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    • 한국철도학회 2011년도 춘계학술대회 논문집
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    • pp.1440-1444
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    • 2011
  • Memory-device is one of the auxiliary components of point-switch machine; connecting front-rod and tongue-rail. The right side and left side of memory-device are different from each other. When there would be a derailing accident of rolling stock or motor-car, the memory-device properly bends and protects the internal of point-switch machine. Memory-device is one of the important site maintenance spare parts. Memory-device for each of right and left side should be secured so that they can be installed on correct side during an exchange work. This study suggests the development of memory-device with different left and right side and the performance test of it. The study intends to contribute in the convenience improvement of maintenance by improving the unification of memory-device.

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Implementation of a ZVS Three-Level Converter with Series-Connected Transformers

  • Lin, Bor-Ren
    • Journal of Power Electronics
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    • 제13권2호
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    • pp.177-185
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    • 2013
  • This paper studies a soft switching DC/DC converter to achieve zero voltage switching (ZVS) for all switches under a wide range of load condition and input voltage. Two three-level PWM circuits with the same power switches are adopted to reduce the voltage stress of MOSFETs at $V_{in}/2$ and achieve load current sharing. Thus, the current stress and power rating of power semiconductors at the secondary side are reduced. The series-connected transformers are adopted in each three-level circuit. Each transformer can be operated as an inductor to smooth the output current or a transformer to achieve the electric isolation and power transfer from the input side to the output side. Therefore, no output inductor is needed at the secondary side. Two center-tapped rectifiers connected in parallel are used at the secondary side to achieve load current sharing. Due to the resonant behavior by the resonant inductance and resonant capacitance at the transition interval, all switches are turned on at ZVS. Experiments based on a 1kW prototype are provided to verify the performance of proposed converter.

기둥측면충돌시험법에서 WorldSID와 ES-2re 더미 안전성에 대한 해석적 연구 (Simulation Analysis for Comparison of WorldSID and ES-2re Dummy in Pole Side Impact Test Methods)

  • 윤영한;한완희;최문영;이은덕;김대업
    • 자동차안전학회지
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    • 제4권2호
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    • pp.27-31
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    • 2012
  • In Korea, side impact type accidents are one of the main cause of fatality. MLTM and KATRI established sie impact regulation as well as NCAP type assessments to protect occupants. Recently, WP29 formed a informal group to study a possible harmonization of pole side impact test methods with WorldSID as a GTR. In this paper, two different dummies, ES-2 and WorldSID were evaluated with three different types of pole side impact test methods.

운전석 및 조수석 에어백 단품의 유한요소 모델링과 전개 과정 해석 (Finite Element Modeling of Folded Airbag and Analysis of Deployment Process)

  • 김헌영;이상근;신윤재
    • 한국자동차공학회논문집
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    • 제4권6호
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    • pp.236-246
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    • 1996
  • The deployment process of fully folded airbag is analyzed. The methodology of finite element modeling is presented for flat driver side airbag and 3-dimensional passenger side airbag. 'Initial metric option' is used to model 3-dimensional passenger side airbag before deployment. The deformed shapeds and pressure waveforms inside cushion evaluated from simulation are compared to the test results. The agreements between the simulation and the experiments are satisfactory, and the results of simulation are confirmed to be applied to the design of airbag module.

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