• Journal of Marine Life Science
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• v.5 no.1
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• pp.17-24
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• 2020

We have identified a heat shock protein 70 gene from freshwater snail, Semisulcospira coreana. The freshwater snail HSP70 gene encode a polypeptide of 639 amino acids. Based on bioinformatic sequence characterization, HSP70 gene possessed three classical signature motifs and other conserved residues essential for their functionality. The phylogenetic analysis showed that S. coreana HSP70 had closet relationship with that of golden apple snails, Pomacea canaliculata. The HSP70 mRNA level was significantly up-regulated in response to thermal and salinity challenges. These results are in agreement with the results of other species, indicating that S. coreana HSP70 used be a potential molecular marker in response to external stressors and the regulatory process related to the HSP70 transcriptional response can be highly conserved among species.

• Interaction and multiscale mechanics
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• v.4 no.2
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• pp.139-153
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• 2011

In this paper we develop a fully anisotropic pressure and temperature dependent model to investigate the effect of the microstructure on the shock response of ${\beta}$-HMX molecular single and polycrystals. This micromechanics-based model can account for crystal orientation as well as crystallographic twinning and slip during deformation and has been calibrated using existing gas gun data. We observe that due to the high degree of anisotropy of these polycrystals, certain orientations are more favorable for plastic deformation - and therefore defect and dislocation generation - than others. Loading along these directions results in highly localized deformation and temperature fields. This observation confirms that most of the temperature rise during high rates of loading is due to plastic deformation or dislocation pile up at microscale and not due to volumetric changes.

• The Korean Journal of Applied Statistics
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• v.24 no.5
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• pp.799-807
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• 2011

This study investigates long and short run responses of variables to exogenous shocks by imposing prior restrictions on a contemporaneous structural shock coefficient matrix of the model to identify shocks by endogenous variables in the vector autoregression. The relative importance of each structural shock in variation of each variable is calculated through the identification of proper restrictions (not based on any specific theory but on researcher judgment corresponding to actual situations) and an estimation of the structural vector autoregression. The results of the analyses are found to maintain consistency.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2004.05a
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• pp.177-182
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• 2004

Electronic products are subjected to many different types of shock environment. As the Optical Disc Drive (ODD) market grows, the number of failures related to shock increases. Therefore, it is necessary to improve the performance of cushion package as well as the product design. Cushion materials such as expanded polystyrene are often used to protect electronic products from shock environment. In this paper, the drop analysis of the cushion package f3r optical disc drives was carried out with the explicit method of LS-DYNA and verified by the drop test. For the optimization of package, response surface approximation model was created using central composite design. As a result, cushioning performance was improved under the critical condition and practical design guidelines of cushion package were suggested.

• Structural Engineering and Mechanics
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• v.32 no.2
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• pp.235-249
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• 2009

The response of concrete structures subjected to shock and blast load involves a rapid transient phase, during which material breach may take place. Such an effect could play a crucial role in determining the residual state of the structure and the possible dispersion of the fragments. Modelling of the transient phase response poses various challenges due to the complexities arising from the dynamic behaviour of the materials and the numerical difficulties associated with the evolving material discontinuity and large deformations. Typical modelling approaches include the traditional finite element method in conjunction with an element removal scheme, various meshfree methods such as the SPH, and the mesoscale model. This paper is intended to provide an overview of several alternative approaches and discuss their respective applicability. Representative concrete material models for high pressure and high rate applications are also commented. Several recent application studies are introduced to illustrate the pros and cons of different modelling options.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2005.05a
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• pp.231-231
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• 2005

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2002.05a
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• pp.533-538
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• 2002

This research demonstrates the transient response of a head disk assembly subjected to a half-sine shock pulse in the axial direction. In case of disk analysis, the numerical method presented by Barasch and Chen is used. Galerkin method is used with mode shape by numerical method. head-suspension system is modeled by the cantilever in order to get simulation results. Simulation results about total system of HDA are calculated by Runge-Kutta method.

• Proceedings of the Zoological Society Korea Conference
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• 1999.10b
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• pp.177.1-177
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• 1999

No Abstract, See Full Text

• Journal of Life Science
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• v.16 no.6
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• pp.1052-1059
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• 2006

The heat shock response is induced by environmental stress, pathophysiological state and non-stress conditions and wide spread from bacteria to human. Although translations of most proteins are stopped under a heat shock response, heat shock proteins (HSPs) are produced to protect cell from stress. When heat shock response is induced, conformation of HSF1 was changed from monomer to trimer and HSF1 specifically binds to DNA, which was called a heat shock element(HSE) within the promoter of the heat shock genes. Human HSF1(hHSFl) contains five cysteine(Cys) residues. A thiol group(R-SH) of Cys is a strong nucleophile, the most readily oxidized and nitrosylated in amino acid chain. This consideration suggests that Cys residues may regulate the change of conformation and the activity of hHSF1 through a redox-dependent thiol/disulfide exchange reaction. We want to construct role of five Cys residues of hHSF by redox reagents. According to two studies, Cys residues are related to trimer formation of hHSF1. In this study, we want to demonstrate the correlation between structural change and DNA-binding activity of HSF1 through forming disulfide bond and trimerization. In this results, we could deduce that DNA binding activity of DNA binding domain wasn't affected by redox for always expose outside to easily bind to DNA. DNA binding activity of wild-type HSF's DNA binding domain was affected by conformational change, as conformational structure change (trimerization) caused DNA binding domain.

• Computers and Concrete
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• v.21 no.1
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• pp.55-66
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• 2018

A large main shock may consist of numerous aftershocks with a short period. The aftershocks induced by a large main shock can cause the collapse of a structure that has been already damaged by the preceding main shock. These aftershocks are important factors in structural damages. Furthermore, despite what is often assumed in seismic design codes, earthquakes do not usually occur as a single event, but as a series of strong aftershocks and even fore shocks. For this reason, this study investigates the effect and potential of consecutive earthquakes on the response and behavior of concrete structures. At first, six moment resisting concrete frames with 3, 5, 7, 10, 12 and 15 stories are designed and analyzed under two different records with seismic sequences from real and artificial cases. The damage states of the model frames were then measured by the Park and Ang's damage index. From the results of this investigation, it is observed that the sequences of ground motions can almost double the accumulated damage and increased response of structures. Therefore, it is certainly insufficient to ignore this effect in the design procedure of structures. Also, the use of artificial seismic sequences as design earthquake can lead to non-conservative prediction of behavior and damage of structures under real seismic sequences.