• Title/Summary/Keyword: shizukaol F

Search Result 1, Processing Time 0.016 seconds

Antifungal Activities of Dimeric Sesquiterpenes, Shizukaols C and F, Isolated from Chloranthus japonicus Sieb.

  • Kang, Tae Hoon;Lee, Yun Me;Lee, Won Jung;Hwang, Eui Il;Park, Ki Duk;Choi, Gyung Ja;Moon, Jae Sun;Park, Ho-Yong;Kim, Sung Uk
    • Journal of Microbiology and Biotechnology
    • /
    • v.27 no.7
    • /
    • pp.1272-1275
    • /
    • 2017
  • Two dimeric sesquiterpenes were separated from Chloranthus japonicus Sieb. and identified as shizukaols C and F. They exhibited potent antifungal activities ($MICs=4-16{\mu}g/ml$) in vitro against various plant pathogenic fungi (Pythium ultimum, Phytophthora infestans, Botrytis cinerea, Colletotrichum lagenarium, Alternaria kikuchiana, and Magnaporthe grisea). Shizukaol C showed 88% and 91% protective activities in the greenhouse against Puccinia recondita (wheat leaf rust) and Phytophthora infestans (tomato late blight), respectively, at $100{\mu}g/ml$; shizukaol F exhibited 93% antifungal activity against Puccinia recondita at the same concentration. Therefore, these compounds might serve as interesting candidates for effective antifungal agents.