• Journal of Venture Innovation
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• v.6 no.3
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• pp.221-240
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• 2023

In a recent study conducted in South Korea, a nation grappling with the implications of an increasingly super-aged society, researchers empirically analyzed the factors influencing seniors' satisfaction with financial institutions' wealth management (WM) services. We surveyed 250 seniors who utilized financial institutions' wealth management services. Independent variables such as product(diversity, profitability, stability), employee(expertise, problem-solving ability, customer orientation), physical evidence, process, inheritance service, and trust service were carefully examined. Employing hierarchical regression analysis, we tested hypotheses within an established research model. The findings revealed that variables like product stability and profitability, employee problem-solving ability, customer orientation, process, inheritance service, and trust service significantly positively affected satisfaction with WM services. In contrast, no substantial association was detected between satisfaction and factors like product diversity, employee expertise, or physical evidence. Among the influential factors, the order of impact was determined to be employee customer orientation, problem-solving ability, trust service, product stability, inheritance service, product profitability, and process. This research provided essential insights into the nuanced preferences and needs of seniors concerning wealth management services. The detailed examination of the subject might also shed light on similar challenges faced in the other aging societies. As the global population continues to age, the implications of this study could reach far beyond the borders of South Korea. By understanding these key determinants of satisfaction, financial institutions worldwide can tailor their wealth management services to better meet the unique demands of the senior population.

• Information Systems Review
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• v.23 no.3
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• pp.159-176
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• 2021

Obviating user churn is a prominent strategy to capitalize on online games, eluding the initial investments required for the development of another. Extant literature has examined factors that may induce user churn, mainly from perspectives of motives to play and game as a virtual society. However, such works largely dismiss the service aspects of online games. Dissatisfaction of user needs constitutes a crucial aspect for user churn, especially with online services where users expect a continuous improvement in service quality via software updates. Hence, we examine the relationship between a game's quality management and its user base. With text mining and survival analysis, we identify complaint factors that act as key predictors of user churn. Additionally, we find that enjoyment-related factors are greater threats to user base than usability-related ones. Furthermore, subsequent quasi-experiment shows that improvements in the complaint factors (i.e., via game patches) curb churn and foster user retention. Our results shed light on the responsive role of developers in retaining the user base of online games. Moreover, we provide practical insights for game operators, i.e., to identify and prioritize more perilous complaint factors in planning successive game patches.

• Journal of Life Science
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• v.34 no.5
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• pp.287-295
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• 2024

Hepatocellular carcinoma (HCC) is the second leading cause of cancer-related mortality worldwide, necessitating novel therapeutic strategies. The chemotherapeutic agents used to treat HCC patients are toxic and have serious side effects. Therefore, we investigated the efficacy of anticancer drugs that reduce side effects by targeting tumor cells without causing cytotoxicity in healthy hepatocytes. Berberine, an isoquinoline alkaloid derived from plant compounds, has emerged as a potential candidate for cancer treatment due to its diverse pharmacological properties. The effect of berberine on HepG2 cell viability was determined using the 3-[4,5-dimethylthiazol-2-yl]-2,5-diphenyl tetrazolium bromide assay. HepG2 cell proliferation was determined through a colony-forming assay. The effects of berberine on HepG2 cell migration were evaluated using a wound-healing assay. Berberine inhibited the proliferation of HepG2 cells, as well as colony formation and migration. Berberine treatment increased the expression of autophagy-related genes and proteins, including Beclin-1 and LC3-II, and elevated the activities and mRNA expression of Caspase-9 and Caspase-3. Additionally, in experiments utilizing the Cell-Derived Xenograft animal model, berberine treatment reduced tumor size and weight in a concentration-dependent manner. These results demonstrate the potential of berberine as a versatile anticancer agent with efficacy in both cellular and animal models of hepatocellular carcinoma. The findings herein shed light on berberine's efficacy against HCC, presenting opportunities for targeted and personalized therapeutic interventions.

• Industry Promotion Research
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• v.9 no.2
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• pp.23-28
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• 2024

The study investigated the impact of ESG management activities on the non-financial performance of organizations, focusing on small and medium-sized manufacturing companies. Using data from 78 survey responses, the following results were summarized. Firstly, ESG management activities positively influenced internal customer satisfaction. The correlation coefficient was .679, indicating a moderately strong correlation, and the coefficient of determination (R²) was .461, explaining 46.1% of the variance. Additionally, with a beta value of .679, a t-value of 8.058, and a p-value of .000, ESG management activities had a statistically significant impact on internal customer satisfaction. Secondly, ESG management activities also had a positive impact on corporate trust. The correlation coefficient was .695, indicating a moderately strong correlation, and the coefficient of determination (R²) was .483, explaining 48.3% of the variance. The beta value was .695, the t-value was 8.429, and the significance probability was .000, indicating a significant influence on corporate trust.The study aimed to shed light on the relationship between ESG management activities of small and medium-sized enterprises and their non-financial performance. These results suggest that companies can enhance internal customer satisfaction and corporate trust through fulfilling social responsibilities and practicing sustainable management.

• Journal of the Korea Institute of Building Construction
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• v.24 no.1
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• pp.97-108
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• 2024

This research delves into the escalating concerns of accidents and fatalities in the construction industry over the recent five-year period, focusing on the development of a Safety Perception Model to augment safety measures. Given the rising percentage of elderly workers and the concurrent drop in productivity within the sector, there is a pronounced need for leveraging Fourth Industrial Revolution technologies to bolster safety protocols. The study comprises an in-depth analysis of statistical data regarding construction-related fatalities, aiming to shed light on prevailing safety challenges. Central to this investigation is the formulation of a Safety Perception Model tailored for small-scale construction projects. This model facilitates the quantification of safety risks by evaluating safety grades across construction sites. Utilizing the DWM1000 module, among an array of wireless communication technologies, the model enables the real-time tracking of worker locations and the assessment of safety levels on-site. Furthermore, the deployment of a safety management system allows for the evaluation of risk levels associated with individual workers. Aggregating these data points, the Safety Climate Index(SCLI) is calculated to depict the daily, weekly, and monthly safety climate of the site, thereby offering insights into the effectiveness of implemented safety measures and identifying areas for continuous improvement. This study is anticipated to significantly contribute to the systematic enhancement of safety and the prevention of accidents on construction sites, fostering an environment of improved productivity and strengthened safety culture through the application of the Safety Perception Model.

• Information Systems Review
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• v.20 no.2
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• pp.111-137
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• 2018

Considering the increase in health insurance benefits and the elderly population of the baby boomer generation, the amount consumed by health care in 2020 is expected to account for 20% of US GDP. As the healthcare industry develops, competition among the medical services of hospitals intensifies, and the need of hospitals to manage the quality of medical services increases. In addition, interest in online reviews of hospitals has increased as online reviews have become a tool to predict hospital quality. Consumers tend to refer to online reviews even when choosing healthcare service providers and after evaluating service quality online. This study aims to analyze the effect of sentiment score of healthcare service quality on hospital rating with Yelp hospital reviews. This study classifies large amount of text data collected online primarily into five service quality measurement indexes of SERVQUAL theory. The sentiment scores of reviews are then derived by SERVQUAL dimensions, and an econometric analysis is conducted to determine the sentiment score effects of the five service quality dimensions on hospital reviews. Results shed light on the means of managing online hospital reputation to benefit managers in the healthcare and medical industry.

• IMMUNE NETWORK
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• v.22 no.3
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• pp.22.1-22.25
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• 2022

Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndromecoronavirus-2 (SARS-CoV-2), has spread over the world causing a pandemic which is still ongoing since its emergence in late 2019. A great amount of effort has been devoted to understanding the pathogenesis of COVID-19 with the hope of developing better therapeutic strategies. Transcriptome analysis using technologies such as RNA sequencing became a commonly used approach in study of host immune responses to SARS-CoV-2. Although substantial amount of information can be gathered from transcriptome analysis, different analysis tools used in these studies may lead to conclusions that differ dramatically from each other. Here, we re-analyzed four RNA-sequencing datasets of COVID-19 samples including human bronchoalveolar lavage fluid, nasopharyngeal swabs, lung biopsy and hACE2 transgenic mice using the same standardized method. The results showed that common features of COVID-19 include upregulation of chemokines including CCL2, CXCL1, and CXCL10, inflammatory cytokine IL-1β and alarmin S100A8/S100A9, which are associated with dysregulated innate immunity marked by abundant neutrophil and mast cell accumulation. Downregulation of chemokine receptor genes that are associated with impaired adaptive immunity such as lymphopenia is another common feather of COVID-19 observed. In addition, a few interferon-stimulated genes but no type I IFN genes were identified to be enriched in COVID-19 samples compared to their respective control in these datasets. These features are in line with results from single-cell RNA sequencing studies in the field. Therefore, our re-analysis of the RNA-seq datasets revealed common features of dysregulated immune responses to SARS-CoV-2 and shed light to the pathogenesis of COVID-19.

• Informatization Policy
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• v.31 no.1
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• pp.83-99
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• 2024

This study seeks to shed light on the importance of "advancing administrative computer systems" for research administration efficiency, building upon prior literature, and aims at extending the scholarly discussion on the efficiency of research administration itself. To this end, two research questions were addressed. First, this research explores how research administrators perceive the advocated "advancement of administrative computer systems" in achieving research administration efficiency. Second, it investigates how external bureaucratic control affects burnout among administrative personnel engaged in research administration, and how burnout impacts the research-administration relationship, trust, and ultimately performance. The analysis of interviews and surveys yielded several results. For one, through the analysis of interviews conducted in the field of government-funded research institutions, it was found that "advancing computer systems" is met with practical concerns and skepticism, while also recognized as having the potential to contribute to the efficiency of research administration. Furthermore, it became evident that complex issues are intertwined. From a contrasting standpoint opposing computer advancement, the view that institutional regulations and cultural efficiency should take precedence over technology appears valid and raises a crucial point for consideration. On the other hand, regression analysis related to burnout shows empirical evidence that increased control by central government bureaucrats over administrative staff in government-funded research institutions leads to higher levels of burnout. Such elevated burnout is shown to have detrimental effects on trust between researchers and administrative personnel, as well as on overall performance. Through these discussions, we aim to stimulate academic and government interest in research administration efficiency.

• Korean Journal of Soil Science and Fertilizer
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• v.12 no.4
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• pp.179-187
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• 1980

1) Soils (volcanic ash and muck) were fractionated into particle-size separates (200 - 20, 20 - 2, 2 - 0.5 and finer than $0.5{\mu}$ in diamter), and of which the silt fraction was further fractionated into specific gravity separates (more than 2.0, 2.0 - 1.7, 1.7 - 1.4 and less than 1.4 in $g/cc^3$). And total organic and inorganic phosphorus in the separates were determined. 2) The amounts of total, organic and inorganic phosphorus distributed in the particle-size separates were as follows fine clay > coarse clay > silt > fine sand fraction. The increase rate in the amounts of phosphorus was great in the separates finer than $20{\mu}$, and greatest in the fine clay fraction. 3) The amounts of total, oganic and inorganic phosphorus distributed in the specific gravity separates were as follows: 2.0 - 1.7 > 1.7 - 1.4 > heavier than 2.0 fraction. The increase rate in the amounts of phosphorus was in the following order 2.0 - 1.7 > 1.7 - 1.4 > heavier than 2.0 fraction. 4) Distribution of carbon, amorphous aluminum and free iron oxides in the particle-size separates and the specific gravity separates were examined, and the distribution and the formes of organo-minera1 complexes in the separates were discussed to shed light on the factors affecting the distribution of phosphorous into the separates. And it was estimated that there was close relation among the distribution of organic and inorganic phosphorus, and the distribution and the formes of organo-minera1 complexes.

• Cartoon and Animation Studies
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• s.33
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• pp.293-315
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• 2013

The number of French movies imported to and released in S. Korea is constantly increasing. All French movies released in Korean theatres, however, are not a great success. For the domestic film market and audiences, the idea French cinema is generally equivalent to 'diversity cinema' or 'arthouse films' is common notion. In this respect, French movies introduced throughout the country would be culture product into which one can read other cultural significances different from that of domestic cinema, and also serve significant cultural value to understand diversity in cinema, for domestic audiences. However, it could be said that French movies, in common with Hollywood films, obey rules in the film industry and needs for audience trends. In this content, what the researchers want to do is to analysis the tendency of the domestic audience reception and main causes of commercial success in the domestic film market, analysing Taken produced in France. The analysis, most of all, suggests the consideration for the film industry beside the notion of cultural diversity in cinema, as imported films are released in the domestic theatre. For this, the study examines the promotional strategy the french cinema perceived generally as the arthouse film applies extensively, analysing on Taken, and inquires into factors of commercial success, using SWOT Analysis. This study, the first of all, (briefly) examines what audiences consider when they choose a film to watch, articulating (generally) the choice-and-consume modality of the domestic audience. And then, it examines dominant factors Taken was a commercial success in domestic film market, even though the film is a french film, using SWOT Analysis. On the basis of SWOT Analysis, finally, this study draws up promotional plan for Taken, and shed new light on dominant preconditions, when the foreign cinema would be imported from the now on.