• 한국전산유체공학회지
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• 제17권2호
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• pp.1-10
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• 2012

This paper presents the numerical simulation results of heat transfer and friction loss for a rotating two-pass duct with the airfoil-guide vanes in the turning region. The Kriging model is used as an optimization technique with Reynolds-averaged Navier-Stokes analysis of flow field and heat transfer with shear stress transport turbulent model. To improve the heat transfer performance, angle and location of the airfoil-guide vanes have been selected as design variables. The optimization problem has been defined as a minimization of the objective function, which is defined as a linear combination of heat transfer related term and friction loss related term with a weight factor. The airfoil-guide vanes in the turning region keep the high level of heat transfer while the friction loss has a low value. By comparing the presence or absence of airfoil-guide vanes, it is shown that the airfoil-guide vanes exhibited the best heat transfer performance to improve the blade cooling except the first passage.

• 대한기계학회논문집B
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• 제31권9호
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• pp.780-789
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• 2007

Lock-on phenomenon in the wake of a circular cylinder is investigated at the Reynolds number of 360 using direct numerical simulation (DNS). To induce lock-on, a streamwise velocity perturbation with a frequency of twice the natural shedding frequency is superimposed on the free stream velocity. The Reynolds stress distributions are investigated to analyze the streamwise force balance acting on the recirculation region and the results are compared with the previous experimental result. When the lock-on occurs, the pressure force on the recirculation region is shown to increase mainly due to the reversal of the Reynolds shear stress distribution, which is consistent with our previous results using PIV measurement. It is also shown that, with the lock-on, the strength of the primary vortices increases whereas that of the secondary vortices decreases significantly. Further, under the lock-on condition the wavelength of the secondary vortices increases by as much as 2.5 times.

• 한국가시화정보학회지
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• 제3권2호
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• pp.51-56
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• 2005

Acoustic excitations were imposed to coaxial air jet of non-premixed jet flame with hydrogen gaseous injected axially in the center of the flow. The frequencies of excitation were three dominant resonant frequencies at 1L, 2L, 3L. modes including specially 514 Hz (2L-mode) which was estimated theoretically as longitudinal mode of combustor characteristics. The mixing enhancement by acoustic forcing has been investigated quantitatively using PLIF and PIV. The effect of acoustic excitation on combustion process was significant to enhance mixing rate that coincides with specific resonant frequencies. And the behavior of vortex-interaction on flame structure was a good evidence to investigate the phenomenon of shear/mixing layer of fuel-air jet structure. The results obtained in this study concludes that generated streamwise vortex by acoustic excitation has a potential to enhance the mixing rate and abating NOx emissions.

• Journal of Mechanical Science and Technology
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• 제19권3호
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• pp.887-893
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• 2005

The aggregability of red blood cells (RBCs) was determined by laser backscattering light analysis in a microfluidic channel. Available techniques for RBC aggregation often adopt a rotational Couette-flow using a bob-and-cup system for disaggregating RBCs, which causes the system to be complex and expensive. A disposable microfluidic channel and vibration generating mechanism were used in the proposed new detection system for RBC aggregation. Prior to measurement, RBC aggregates in a blood sample were completely disaggregated by the application of vibration-induced shear. With the present apparatus, the aggregation indexes of RBCs can be measured easily with small quantities of a blood sample. The measurements with the present aggregometer were compared with those of LORCA and the results showed a strong correlation between them. The aggregability of the defibrinogenated blood RBCs is markedly lower than that of the normal RBCs. The noble feature of this design is the vibration-induced disaggregation mechanism, which can incorporate the disposable element that holds the blood sample.

• 한국해안해양공학회지
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• 제5권4호
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• pp.357-368
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• 1993

확산이 지배적인 흐름을 가정하여, 쇄파대의 해향저류와 난류구조에 대한 수치모형이 $ extsc{k}$-$\varepsilon$ 난류모형을 이용하여 개발되었다. 해향저류란 쇄파대에서 바다쪽으로 흐르는 주기평균된 강한 흐름을 말하며 주로 파곡 아래에 나타난다. 롤러에서 쇄파에 의해 발생된 난류는 아래쪽으로 퍼져나가면서 그 기운을 잃게된다. 지배 방정식은 파에 의한 주기평균-전단응력이 고려된 운동 방정식과 쇄파에 의한 난류 에너지 생성이 포함된 $textsc{k}$-와 $\varepsilon$-식으로 구성된다. 이 식들은 삼단계 완전 음해법으로 차분되고, Thomas 알고리즘으로 풀 수 있다. 쇄파지점에 가까운 곳을 제외하면, 모형은 실험값과 좋은 일치를 보여준다

• 한국인쇄학회지
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• 제29권2호
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• pp.45-58
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• 2011

Gravure off-set printing recently is used in electronics display market. This method has advantages of mass production and high printing speed. It is also fine pattern can be implemented. We have manufactured low-curable conductive Ag pastes for gravure off-set printing. When printing, the pastes be used different silver powder shape because of the printing characteristics. The pastes were prepared with silver powder by silver powder shape and size, epoxy resin, solvent and homogenized on a standard three-roll mill. And the pastes exhibited a shear-thinning flow at viscosity profile. Moreover the adhesive strength and resistivity of silver film had a good characteristics. With the manufactured paste in this study, touch panel had is manufactured and it had $4{\times}10-5{\Omega}.cm$.

• Wind and Structures
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• 제26권5호
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• pp.305-315
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• 2018

A numerical study based on a delayed detached eddy simulation (DDES) is conducted to investigate the aerodynamic mechanism behind the suppression of vortex-induced vibrations (VIVs) of twin box girders by central grids, which have an inhibition effect on VIVs, as evidenced by the results of section model wind tunnel tests. The mean aerodynamic force coefficients with different attack angles are compared with experimental results to validate the numerical method. Next, the flow structures around the deck and the aerodynamic forces on the deck are analyzed to enhance the understanding of the occurrence of VIVs and the suppression of VIVs by the application of central grids. The results show that shear layers are separated from the upper railings and lower overhaul track of the upstream girder and induce large-scale vortices in the gap that cause periodical lift forces of large amplitude acting on the downstream girder, resulting in VIVs of the bridge deck. However, the VIVs are apparently suppressed by the central grids because the vortices in the central gap are reduced into smaller vortices and become weaker, causing slightly fluctuating lift forces on the deck. In addition, the mean lift force on the deck is mainly caused by the upstream girder, whereas the fluctuating lift force is mainly caused by the downstream girder.

• Smart Structures and Systems
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• 제13권3호
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• pp.473-500
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• 2014

Tuned mass dampers (TMDs) have been installed in many high-rise buildings, to improve their resiliency under dynamic loads. However, high-rise buildings may experience natural frequency changes under ambient temperature fluctuations, extreme wind loads and relative humidity variations. This makes the design of a TMD challenging and may lead to a detuned scenario, which can reduce significantly the performance. To alleviate this problem, the current paper presents a proposed approach for the design of a robust and efficient TMD. The approach accounts for the uncertain natural frequency, the optimization objective and the input excitation. The study shows that robust design parameters can be different from the optimal parameters. Nevertheless, predetermined optimal parameters are useful to attain design robustness. A case study of a high-rise building is executed. The TMD designed with the proposed approach showed its robustness and effectiveness in reducing the responses of high-rise buildings under multidirectional wind. The case study represents an engineered design that is instructive. The results show that shear buildings may be controlled with less effort than cantilever buildings. Structural control performance in high-rise buildings may depend on the shape of the building, hence the flow patterns, as well as the wind direction angle. To further increase the performance of the robust TMD in one lateral direction, active control using LQG and fuzzy logic controllers was carried out. The performance of the controllers is remarkable in enhancing the response reduction. In addition, the fuzzy logic controller may be more robust than the LQG controller.

• Journal of Microbiology and Biotechnology
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• 제2권2호
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• pp.141-151
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• 1992

Physiological changes of the murine hybridoma cell line $S3H5/\gamma{2bA2}$ during adaptation to RPMI 1640 medium with 1%(v/v) fetal bovine serum were characterized in terms of cell growth, antibody production, morphology, and metabolic quotients. Cells adapted to 1% serum medium in T-flasks became sensitive to shear induced by mechanical agitation and required at least 5% serum in the medium or spent medium for cell growth in spinner flasks, while cells adapted to 10% serum medium in T-flasks could grow in 1% serum medium in spinner flasks. Consequently, long-term adaptation to low serum media may not give the expected growth enhancement. After adaptation to 1% serum medium, changes in cell morphology were observed. The cells in 10% serum medium were uniform and circular, while cells in 1% medium were irregularly shaped. The DNA contents, which were measured by flow cytometry, were almost constant among the cells in the range of 1% to 10%. Further, no significant changes in energy metabolism and specific monoclonal antibody production rate were observed among these cells.

• 약학회지
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• 제40권4호
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• pp.411-417
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• 1996

Epidermal growth factor(EGF), a potential healing agent for wounds and burns, has been formulated to topical gels with the hydrophilic polymers, Carbopol 934P. Physicochemical c haracteristics of the aqueous gels were evaluated by rheological properties and pH changes on storage. The gels were relatively stable at $4^{\circ}C$ and room temperature showing no changes in pH for two weeks, and revealed the rheogram of shear thinning plastic flow with the yield values in the range of 40 to 70dyne/$cm^2$. In vivo healing effects of different gel formulations have been compared with water-soluble and oleaginous ointments in full-thickness wound mouse model. The gel systems resulted in better wound healing effects than the other ointments. Furthermore, liposomal Carbopol gel has been developed by the addition of EGF-containing liposomal suspension into the Carbopol gel. The enhanced wound healing effects have been observed in the liposomal gel system, compared to the other gels and conventional ointments.