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Zygomaticotemporal suture maturation evaluation in Chinese population using cone-beam computed tomography images

  • Yifan Li;Ruomei Li;Jiajun Shi;Yuhua Shan;Zhenqi Chen
    • The korean journal of orthodontics
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    • v.53 no.4
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    • pp.232-240
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    • 2023
  • Objective: This study aimed to evaluate the zygomaticotemporal suture (ZTS) maturation, analyze the age distribution patterns of ZTS maturation stages, and investigate the relationship between ZTS and cervical vertebral maturation (CVM). Methods: A total of 261 patients who underwent cone-beam computed tomography (112 males, mean age, 13.1 ± 3.3 years; 149 females, mean age, 13.7 ± 3.1 years) were examined to evaluate the ZTS stages. The ZTS stages were defined based on a modified method from previous studies on zygomaticomaxillary sutures. Differences between groups and correlations between indicators were analyzed using the Spearman correlation test, intraclass coefficient of correlation (ICC), one-way analysis of variance and rank sum test. Statistical significance was set at p < 0.05. The diagnostic value of CVM stages in identifying ZTS maturation stages was evaluated using positive likelihood ratios (LRs). Results: A positive relationship was found between the ZTS and CVM stage (r = 0.747, ICC = 0.621, p < 0.01) and between the ZTS stage and chronological age (r = 0.727, ICC = 0.330, p < 0.01). Positive LRs > 10 were found for several cervical stages (CSs), including CS1 and CS2 for the diagnosis of stage B, CS1 to CS3 for the diagnosis of stages B and C, and CS6 for the diagnosis of stages D and E. Conclusions: The ZTS maturation stage may be more relevant to the CVM stage than to the chronological age. The CVM stages can be good indicators for clinical decisions regarding maxillary protraction, except for CS4 and CS5.

IL-34 Aggravates Steroid-Induced Osteonecrosis of the Femoral Head via Promoting Osteoclast Differentiation

  • Feng Wang;Hong Sung Min;Haojie Shan;Fuli Yin;Chaolai Jiang;Yang Zong;Xin Ma;Yiwei Lin;Zubin Zhou;Xiaowei Yu
    • IMMUNE NETWORK
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    • v.22 no.3
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    • pp.25.1-25.11
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    • 2022
  • IL-34 can promote osteoclast differentiation and activation, which may contribute to steroid-induced osteonecrosis of the femoral head (ONFH). Animal model was constructed in both BALB/c and IL-34 deficient mice to detect the relative expression of inflammation cytokines. Micro-CT was utilized to reveal the internal structure. In vitro differentiated osteoclast was induced by culturing bone marrow-derived macrophages with IL-34 conditioned medium or M-CSF. The relative expression of pro-inflammation cytokines, osteoclast marker genes, and relevant pathways molecules was detected with quantitative real-time RT-PCR, ELISA, and Western blot. Up-regulated IL-34 expression could be detected in the serum of ONFH patients and femoral heads of ONFH mice. IL-34 deficient mice showed the resistance to ONFH induction with the up-regulated trabecular number, trabecular thickness, bone value fraction, and down-regulated trabecular separation. On the other hand, inflammatory cytokines, such as TNF-α, IFN-γ, IL-6, IL-12, IL-2, and IL-17A, showed diminished expression in IL-34 deficient ONFH induced mice. IL-34 alone or works in coordination with M-CSF to promote osteoclastogenesis and activate ERK, STAT3, and non-canonical NF-κB pathways. These data demonstrate that IL-34 can promote the differentiation of osteoclast through ERK, STAT3, and non-canonical NF-κB pathways to aggravate steroid-induced ONFH, and IL-34 can be considered as a treatment target.

Percutaneous Sacroplasty for Painful Sacral Metastases Involving Multiple Sacral Vertebral Bodies: Initial Experience with an Interpedicular Approach

  • Qing-Hua Tian;He-Fei Liu;Tao Wang;Ying-Sheng Cheng;Chun-Gen Wu
    • Korean Journal of Radiology
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    • v.20 no.6
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    • pp.939-946
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    • 2019
  • Objective: To report our initial experience of percutaneous sacroplasty (PSP) with an interpedicular approach for treating painful sacral metastases involving multiple sacral vertebral bodies. Materials and Methods: This study prospectively enrolled 10 consecutive patients (six men and four women; mean age, 56.3 ± 13.8 years) who underwent PSP for painful sacral metastases involving multiple sacral vertebral bodies from March 2017 to September 2018. Visual analogue scale (VAS) scores, Oswestry disability index (ODI) values, and the number of opioids prescribed to the patients were assessed before and after PSP. The procedure duration, length of hospitalization, and complications were also recorded. Results: Mean VAS and ODI declined significantly from 6.90 ± 1.20 and 74.40 ± 5.48 before the procedure to 2.70 ± 1.34 and 29.60 ± 14.57 after the procedure, respectively (p < 0.01). The median number of opioids prescribed per patient decreased from 2 (interquartile range [IQR] 1-3) pre-procedure to 1 (IQR 0-3) post-procedure (p < 0.01). Nine of the 10 patients showed no or decreased opioid usage, and only 1 patient showed unchanged usage. The mean procedure duration was 48.5 ± 3.0 minutes. The average length of hospitalization was 4.7 ± 1.7 days. Extraosseous cement leakage occurred in three cases without causing any clinical complications. Conclusion: PSP with an interpedicular approach is a safe and effective treatment in patients with painful sacral metastases involving multiple sacral vertebral bodies and can relieve pain and improve mobility.

Influence of Illumination with Xenon or Sulfur Lamp on Growth of Tomato Seedlings

  • Chen, Qilin;Yu, Xinjian;Weng, Jun;Chen, Jinxing;Liu, Yuequn;Gao, Jinpeng;Xu, Chunhe
    • Journal of Photoscience
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    • v.9 no.2
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    • pp.391-393
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    • 2002
  • Effects of illumination with xenon or sulfur lamp on growth of tomato seedlings were studied. Results showed no obvious differences in net photosynthetic rate and apparent quantum efficiency. In comparison with xenon lamp, illumination with sulfur lamp slightly reduced ChI a and ChI b content in leaves, relatively shortened epicotyl and hypocotyl length, but significantly increased anthocyanin content of leaves and promoted root growth of tomato seedling plants.

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Prospects for the Management of Shanghai Harbour

  • He Yegang
    • Proceedings of the KOR-KST Conference
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    • 1993.07a
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    • pp.99-105
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    • 1993
  • This Article analyses the present situation of Shanghai Harbour and the Harbour's important role in the development of chinese economy. The article forecasts that the yearly tonnage turnover of the port will reach about 200 million tons in the year of 2000, possibly reach to 270--300 million tons by the end of 2020. it also forecasts that the container handling capacity of the port will be 2 million TEUS in 2000 and 6 million TEUS in 2020 respectively. In order to keep pace with the present situation of opening up and developing Pudong new area, this article suggests that the strategic target of the management and development of Shanghai Harbour should be : grasp the opportunity of opening up and developing Pudong, take the building of the deep-waterway port as the main task, which can accept the third or fourth generation international container ships, bring into full play the traditional advantages the Harbour has, unfold the businesses in other fields, participate in the marketing competition, speed up the development of the Harbour itself, make efferts to build Shanghai Harbour into a port-industry-trade-transportation integral modernized international deep-water key port.

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Study on rectangular concrete-filled steel tubes with unequal wall thickness

  • Zhang, Yang;Yu, Chen-Jiang;Fu, Guang-Yuan;Chen, Bing;Zhao, She-Xu;Li, Si-Ping
    • Steel and Composite Structures
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    • v.22 no.5
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    • pp.1073-1084
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    • 2016
  • Rectangular concrete-filled steel tubular columns with unequal wall thickness were investigated in the paper. The physical centroid, the centroidal principal axes of inertia, and the section core were given. The generalized bending formula and the generalized eccentric compression formula were deduced, and the equation of the neutral axis was also provided. The two rectangular concrete-filled steel tubular stub specimens subjected to the compression load on the physical centroid and the geometric centroid respectively were tested to verify the theoretical formulas.

Reevaluating the overhead of data preparation for asymmetric multicore system on graphics processing

  • Pei, Songwen;Zhang, Junge;Jiang, Linhua;Kim, Myoung-Seo;Gaudiot, Jean-Luc
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.10 no.7
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    • pp.3231-3244
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    • 2016
  • As processor design has been transiting from homogeneous multicore processor to heterogeneous multicore processor, traditional Amdahl's law cannot meet the new challenges for asymmetric multicore system. In order to further investigate the impact factors related to the Overhead of Data Preparation (ODP) for Asymmetric multicore systems, we evaluate an asymmetric multicore system built with CPU-GPU by measuring the overheads of memory transfer, computing kernel, cache missing and synchronization. This paper demonstrates that decreasing the overhead of data preparation is a promising approach to improve the whole performance of heterogeneous system.

KNOCKDOWN OF IGF-1R BY ANTISENSE OLIGODEOXYNUCLEOTIDE AUGUMENTS THE SENSITIVITY OF BLADDER CANCER CELLS TO MMC

  • Wu, Shu-Fang;Sun, Hong-Zhi;Tu, Zeng-Hong
    • Proceedings of the Korean Society of Toxicology Conference
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    • 2001.10a
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    • pp.203-204
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    • 2001
  • Background and Aim: Transitional cell carcinoma (TCC) of the bladder represents the fifth most prevalent malignancy in Western population, with peak incidence found in males of the 50- to 70-year-old age group. A major problem in the management of bladder cancer is the low sensitivity of a large proportion (approximately 40%) among bladder tumors to chemotherapy and the high risk for recurrence of bladder tumors after transurethral resection.(omitted)

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A Numerical Study on Cavitation Suppression Using Local Cooling

  • Zhang, Yuan-Yuan;Sun, Xiao-Jing;Huang, Dian-Gui
    • International Journal of Fluid Machinery and Systems
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    • v.3 no.4
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    • pp.292-300
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    • 2010
  • This study strives to develop an effective strategy to inhibit cavitation inception on hydrofoils by using local cooling technique. By setting up a temperature boundary condition and cooling a small area on the upper surface of a hydrofoil, the fluid temperature around the cooling surface will be decreased and thereby the corresponding liquid saturation pressure will drop below the lowest absolute pressure within the flow field. Hence, cavitation can never occur. In this paper, a NACA0015 hydrofoil at $4^{\circ}$ angle of attack was numerically investigated to verify the effectiveness of the proposed technique. The CFD results indicate that the cooling temperature and the cooling surface roughness are the critical factors affecting the success of such technique used for cavitation suppression.