• Title/Summary/Keyword: sexual dysfunction

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Treatment of Lymphedema of the Scrotum and Penis Using Scrotal Flaps (음낭피판을 이용한 음낭과 음경 림프부종의 치료)

  • Lee, Do-Heon;Park, Sun-Hyung;Park, Jung-Joon;Hwang, Jae-Ha;Kim, Kwang-Seog;Lee, Sam-Yong
    • Archives of Plastic Surgery
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    • v.38 no.6
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    • pp.899-902
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    • 2011
  • Purpose: Lymphedema of the scrotum and penis is a functionally and emotionally incapacitating problem for patients. Patients suffer pain from swelling, chronic irritation, repeated infections, drainage, and sexual dysfunction. Although there are various methods for the treatment of scrotal and penial lymphedema, achieving a satisfactory reconstruction in severe cases still remains a challenge due to the lack of locally available tissue. Methods: A 33-year-old man sustained severe lymphedema of the scrotum and penis. He reported a history of swelling since 25 years, which had been intensified during the past few months. There was no history of irritation, surgery, trauma, infection or travel to endemic countries. The authors reconstructed the scrotum and penis using 4 scrotal flaps made by incising the enlarged scrotum crucially. Results: The postoperative course was uneventful. Histopathologic examination showed nonspecific chronic inflammation. The patient was followed up for 18 months and a good reconstructive result was obtained with no recurrence. Conclusion: The authors' method is safe and easy to perform. This method may be a convenient and reliable alternative for the treatment of severe lymphedema of the scrotum and penis.

A Case of Isolated Gonadotropin Deficiency with Negative KALIG-1 Gene (KALIG-1유전자 음성을 보인 격리성 성선자극호르몬 부족증 1례)

  • Nam, Y.S.;Lee, S.H.;Kwak, I.P.;Yoon, T.K.;Cha, K.Y.
    • Clinical and Experimental Reproductive Medicine
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    • v.25 no.3
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    • pp.293-297
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    • 1998
  • Hypogonadotropic hypogonadism, or the lack of function of the testis or ovary secondary to the lack of pituitary and or hypothalamic trophic hormones, is also sometimes generally termed Kallmann's syndrome. Whether such deficiencies arise from an inborn error of hypothalamic organization and pituitary connection or damage to the hypothalamic pituitary system in prepubertal life, the manifestations of a eunuchoid or apubertal individual with potentially competent pituitary and gonadal function will result. Beyond the achievement of puberty, a similar situation can be recreated by the administration of a long-acting GnRH analog or by conditions of secondary hypothalamic dysfunction such as anorexia nervosa where shutdown of GnRH and its resultant effects cause cessation of gonadal function and even a regression of secondary sexual characteristics. Technically, these conditions are not Kallmann's syndrome but one must recognize the similarities. We have experienced a case of isolated gonadotropin deficiency which showed a negative KALIG-1 gene in infertile patient with primary amenorrhea. So we report this case with a brief review of literatures.

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Comparative Study of the Papaverine-induced Artificial Erection and the Nocturnal Penile Erection (Papaverine 주사에 의한 인위적 음경발기와 야간의 수면중 음경발기의 비교관찰)

  • Choi, I.G.;Oh, M.M.;Kim, S.C.
    • Clinical and Experimental Reproductive Medicine
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    • v.16 no.1
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    • pp.107-112
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    • 1989
  • In order to compare the nocturnal penile erection and the erection induced by intracavernosal injection of papaverine, digital palpation of penis, erectile angle, and the rigigram using $Rigiscan^{(R)}$ were evaluated in 38 erectile dysfunction patients(13 psychogenic, 18 vasculogenic, 1 neurogenic, 3 vasculo-neurcgenic, and 3 undetermined). The following results were obtained. 1. Among the 32 patients of the nocturnal penile erection > 40% on rigigram, only 15 patients(46.9 %) demonstrated rigidity > 4+, a sufficient rigidity for sexual intercourse, on papaverine test. 2. The maximal degree of rigidity was also measured by the erectile angle of the penis. Among the 32 patients of nocturnal penile erection > 40% on rigigram, 23 patients(71.9%) had an angle > $45^{\circ}$. 3. Sixteen patients(42.1%) demonstrated similar increase in the maximal circumferential expansion of the distal portion of the penis on nocturnal penile erection and papaverine-induced erection. Nineteen patients showed larger circumferential expansion on nocturnal penile erection than on papaverine-induced erection. Fifteen patients showed similar circumferential increase of the basal portion of the penis on nocturnal penile erection and artificial erection, while 12 patients(31.6 %) showed larger circumferential increase on artificial erection than on nocturnal penile erection. 4. In the 15 patients of nocturnal penile erection > 40 % on rigigram and > 4+ on papaverine test, the duration of maintenance of the maximum erection on nocturnal penile erection and artificial erection proved to be not proportional. Thus, the arthficial erection induced by papaverine and the nocturnal penile erection can not to be said to be of same in nature and therefore, in order to make more definite diagnosis, both tests should be done and compared.

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Administration Duration Dependent Effects of Morindae Radix Extract Solution on Reproductive Capacities in Mice (수컷 생쥐 생식능력(生殖能力)에 대한 파극(巴戟)의 투약기간별(投藥其間別) 효과(效果))

  • Oh, Jae-Sung;Lee, Chang-Hun;Jang, Jun-Bock;Lee, Kyung-Sub;Cho, Jung-Hoon
    • The Journal of Korean Medicine
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    • v.27 no.3 s.67
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    • pp.63-76
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    • 2006
  • Objective: These studies were undertaken to evaluate the effects of the different administration duration of Morindae Radix extract solution on spermatogenic abilities such as concentration, motility and morphological normality of sperm from the testes and the activities of sperm hyaluronidase. Materials and Method: We used 8-week-old ICR mice and administered 0.3mg/g extract solution of Morindae Radix once a day for 30, 60, 90 and 120 days. The control group was administered normal saline in the same way and duration. We examined the number of total, motile and normal sperm from the cauda epididymis. We also compared the testicular tissue, especially seminiferous tubules, between the control and treated groups by histochemical methods. Finally, we observed the difference of sperm hyaluronidase activities between the control and treated groups. Results: Significant administration duration-dependent differences were observed in the concentration of total sperm, motility and normality of spermatozoa of the Morindae Radix extract solution administered groups compared to the control group. In the histological analysis of the testicular tissues, the enlargement of testicular lobe diameter and apparent vasculogenesis between testicular lobes were observed in the Morindae Radix extract solution administered groups compared to the control group. Also, the activity of hyaluronidase was significantly increased in the Morindae Radix extract solution administered groups compared to the control group. Conclusions: This study shows that the beneficial effect of Morindae Radix extract solution on the concentration, motility and morphology of sperm, the testicular tissues and the activities of sperm hyaluronidase increased the greater the duration the mice were administered it. We suggest that Morindae Radix may be useful for the treatment of male sexual dysfunction and infertility.

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Review of Effect on Heat-generating Plaster Therapy for Chronic Prostatitis (만성전립선염에 대한 열(熱) 발생을 적용한 부첩요법(敷貼療法)의 효과에 관한 고찰)

  • Seo, Hee Jeong;Bae, Goeun;Choi, JinYong;Shim, SoHyun;Seo, HyungBum;Kim, So Yeon;Kwon, JungNam;Yun, YoungJu;Lee, In;Choi, JunYong;Han, ChangWoo;Hong, JinWoo;Park, SeongHa
    • The Journal of Korean Medicine
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    • v.39 no.2
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    • pp.29-35
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    • 2018
  • Objectives: The aim of this study is to investigate the effect of Heat-generating plaster therapy on Chronic prostatitis Methods: We searched articles from Academic Journals(CAJ) online databases. Searching keywords were '貼敷', '慢性前列腺炎', '敷貼', '慢性前列腺炎'. Results: Among the articles published until October 2017, The 18 articles were found. After reviewing the title, abstract and original article, the 3 articles were selected finally to rule out completely different prescriptions. Conclusions: The effect of Heat-generating plaster therapy on symptoms such as urinary frequency, dysuria, nocturia and sexual dysfunction due to chronic prostatitis was satisfactory. Especially the method is simple and safe, easy to use, patient-friendly, and convenient.

A STUDY ON THE RANGE OF MANDIBULAR MOVEMENT OF NORMAL AND CLASS III MALOCCLUSION CHILDREN (정상교합과 III급 부정교합아동의 하악운동 범위에 대한 연구)

  • Jhee, In-Ae
    • Journal of the korean academy of Pediatric Dentistry
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    • v.11 no.1
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    • pp.41-56
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    • 1984
  • The purpose of this study is to obtain the normal range of mandibular movement for 13 year old boys and girls, and to compare it to the range of mandibular movement of class III patient and normal adult for diagnosis and prognosis of class III malocclusion and TMJ dysfunction. The subjects were 20 normal boys 20 normal girls 22 class III boys and 18 class III girls. The author measured the ranges and shapes of movement of the mandible in the frontal, sagittal and horizontal trajectories using Saphon visitrainer C II (Tokyo Shizaisha Inc.) for the subjects. The results obtained are as follows: 1) The mean for maximum right laterotrusion in the frontal trajectory were 11.96mm in N.B., 11.10mm in N.G., 11.32mm in III. B., 11.24mm in III G. The mean for maximum left laterotrusion were 11.48mm, 11.0mm, 10.91mm, 10.44mm respectively, Area of border movement were 7.16cm in N.B., 6.59cm in N.G., 7.29cm in III. B., 7.50cm in III. G. 2) The mean for maximum protrusion in the sagittal trajectory were 11.7mm in N.B., 11.4mm in N.G.,11.87mm in III B., and 11.02mm in III. G. 3) The mean for maximum protrusion in the horizontal trajectory were 10.20mm in N.B.,10.00 mm in N.G., 9.12mm for III. B. and 9.36mm in III. G. 4) The mean for maximum protrusion of Class III subjects were shorter than those of normal subjects. 5) There was no sexual difference in the range of mandibular movement for 13 year old subjects. N.B; Normal boys N.G.; Normal girls III.B.; Class III boys III. G.; Class III girls.

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Development of Home Care Nursing Intervention Protocols for Spinal Cord Injury Patients Based on NIC (NIC에 근거한 척수손상환자의 가정간호 중재 프로토콜 개발)

  • Moon, Seong-Mi;Kim, Sun-Hee
    • Journal of Korean Academic Society of Home Health Care Nursing
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    • v.8 no.1
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    • pp.25-37
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    • 2001
  • Spinal cord injury patients need rehabilitation after the acute stage. They should be cared for at home to decrease hospitalization. Home care nurses play an important role in making spinal cord injury patients who have physical. and psychosocial problems do their best. For effective care, home care nurses need standardized nursing intervention protocols for spinal cord injury patients, but they are rarely developed. Therefore, this study was conducted to develop home care nursing protocols, based on NIC, that are applicable to spinal cord injury patients at home. Forty home care nursing charts of spinal cord injury patients registered in a home care nursing agency from July 1st, 1994 to August 31st, 1999 in S city were analyzed. Fifteen home care nurses participated in this study as a user validity validation group, The results of this study are as follows. 1. Fifteen nursing diagnoses were classified through the frequency analysis of home care nursing charts and previous literature for 40 spinal cord injury patients: altered urinary elimination, constipation, high risk for impaired skin integrity, chronic pain, impaired skin integrity, impaired social interaction, knowledge deficit, bowel incontinence, high risk for injury, altered role performance, care giver role strain, impaired physical mobility, sexual dysfunction, dysreflexia, and ineffective breathing pattern. 2. Based on validation by experts and user validities, 93 nursing interventions which were above ICV(Index of Content Validity) .80 were chosen. 3. Nursing intervention protocols which showed above ICV .80 were developed.

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Quality of Life of Antipsychotic-Induced Hyperprolactinemia in Patients with Schizophrenia (항정신병약물로 유발된 고프로락틴혈증을 가진 조현병 환자의 삶의 질)

  • Woo, Seonjin;Jin, Bo-Hyun;Won, Seunghee
    • Journal of the Korean society of biological therapies in psychiatry
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    • v.24 no.3
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    • pp.218-229
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    • 2018
  • Objectives : Antipsychotic-induced hyperprolactinemia causes physical symptoms, such as amenorrhea, galactorrhea, gynecomastia, sexual dysfunction, and bone density loss, as well as psychiatric symptoms, such as depression and cognitive impairments. This study aimed to clarify the associations among hyperprolactinemia caused by antipsychotics in patients with schizophrenia, psychiatric pathology, and psychosocial factors. Methods : Ninety-nine patients with schizophrenia in the psychiatry department of a university hospital were registered between 2015 and 2017. All participants were assessed using structured questionnaires to elucidate psychopathology, social function, quality of life, and hyperprolactinemia-related side effects. The standard levels for hyperprolactinemia were 24ng/mL for women and 20ng/mL for men. Results : The average prolactin levels were $73.45{\pm}49.37ng/mL$ in patients with hyperprolactinemia and $9.16{\pm}6.42ng/mL$ in those without hyperprolactinemia. The average prolactin level in women was significantly higher than that in men(p=0.04). Risperidone was most commonly administered in patients with hyperprolactinemia(58.1%, p<0.01), while aripiprazole was most commonly administered in those without hyperprolactinemia(44.7%, p<0.01). Patients with hyperprolactinemia had significantly higher Positive and Negative Syndrome Scale(p=0.03) and Patient Health Questionnaire-9(p=0.05) scores and had significantly lower Social and Occupational Functioning Assessment Scale(p=0.04) and Strauss-Carpenter Levels of Functioning Scale(p=0.03) scores than patients without hyperprolactinemia. There were no significant differences in side effects or quality of life between the two groups. Conclusion : These findings demonstrate that hyperprolactinemia confers negative effects on depression and social function, but does not directly affect the quality of life. These results suggest that patients with schizophrenia who take antipsychotics that increase prolactin or cause side effects of hyperprolactinemia need to be assessed and receive interventions for depression.

Effects of Foot Bath Therapy on Menopausal Symptoms and Sleep in Women in Their 50s (족욕요법이 50대 여성의 갱년기 증상 및 수면에 미치는 영향)

  • Jeon, Gesam;Jeon, Yowon;Kim, Wonbin
    • Journal of Naturopathy
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    • v.9 no.2
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    • pp.57-61
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    • 2020
  • Purpose: Purpose: This study was to study the effect of foot bathing on menopausal symptoms and sleep disorders in female subjects in their 50s with menopausal symptoms. Methods: After 12 weeks of foot bath therapy three times a week, pre- and post-menopausal signs were measured. Results: Subjects with hot flashes, heart discomfort, sleep problems, depression, irritability, anxiety, physical and mental fatigue, sexual problems, urination problems, vaginal dryness, and joint and muscle discomfort significantly improved after than before(p < .001). Subjective sleep quality, sleep incubation period, sleep duration, sleep disturbance score, sleep drug use, and sleep dysfunction significantly decreased after foot bath than before(p < .001). Habitual sleep efficiency increased considerably. Conclusions: The subjects showed overall improvement in menopausal symptoms and sleeping quality after a foot-bath. Therefore, foot bath therapy is evaluated as a natural healing therapy suitable for improving menopausal symptoms and sleep.

Clinical Applications and Efficacy of Korean Ginseng (고려인삼의 주요 효능과 그 임상적 응용)

  • Nam, Ki-Yeul
    • Journal of Ginseng Research
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    • v.26 no.3
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    • pp.111-131
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    • 2002
  • Korean ginseng (Panax ginseng C.A. Meyer) received a great deal of attention from the Orient and West as a tonic agent, health food and/or alternative herbal therapeutic agent. However, controversy with respect to scientific evidence on pharmacological effects especially, evaluation of clinical efficacy and the methodological approach still remains to be solved. Author reviewed those articles published since 1980 when pharmacodynamic studies on ginseng have intensively started. Special concern was paid on metabolic disorders including diabetes mellitus, circulatory disorders, malignant tumor, sexual dysfunction, and physical and mental performance to give clear information to those who are interested in pharmacological study of ginseng and to promote its clinical use. With respect to chronic diseases such as diabetes mellitus, atherosclerosis, high blood pressure, malignant disorders, and sexual disorders, it seems that ginseng plays preventive and restorative role rather than therapeutics. Particularly, ginseng plays a significant role in ameliorating subjective symptoms and preventing quality of life from deteriorating by long term exposure of chemical therapeutic agents. Also it seems that the potency of ginseng is mild, therefore it could be more effective when used concomitantly with conventional therapy. Clinical studies on the tonic effect of ginseng on work performance demonstrated that physical and mental dysfunction induced by various stresses are improved by increasing adaptability of physical condition. However, the results obtained from clinical studies cannot be mentioned in the indication, which are variable upon the scientist who performed those studies. In this respect, standardized ginseng product and providing planning of the systematic clinical research in double-blind randomized controlled trials are needed to assess the real efficacy for proposing ginseng indication. Pharmacological mode of action of ginseng has not yet been fully elucidated. Pharmacodynamic and pharmacokinetic researches reveal that the role of ginseng not seem to be confined to a given single organ. It has been known that ginseng plays a beneficial role in such general organs as central nervous, endocrine, metabolic, immune systems, which means ginseng improves general physical and mental conditons. Such multivalent effect of ginseng can be attributed to the main active component of ginseng,ginsenosides or non-saponin compounds which are also recently suggested to be another active ingredients. As is generally the similar case with other herbal medicines, effects of ginseng cannot be attributed as a given single compound or group of components. Diversified ingredients play synergistic or antagonistic role each other and act in harmonized manner. A few cases of adverse effect in clinical uses are reported, however, it is not observed when standardized ginseng products are used and recommended dose was administered. Unfavorable interaction with other drugs has also been suggested, which the information on the products and administered dosage are not available. However, efficacy, safety, interaction or contraindication with other medicines has to be more intensively investigated in order to promote clinical application of ginseng. For example, daily recommended doses per day are not agreement as 1-2g in the West and 3-6 g in the Orient. Duration of administration also seems variable according to the purpose. Two to three months are generally recommended to feel the benefit but time- and dose-dependent effects of ginseng still need to be solved from now on. Furthermore, the effect of ginsenosides transformed by the intestinal microflora, and differential effect associated with ginsenosides content and its composition also should be clinically evaluated in the future. In conclusion, the more wide-spread use of ginseng as a herbal medicine or nutraceutical supplement warrants the more rigorous investigations to assess its effacy and safety. In addition, a careful quality control of ginseng preparations should be done to ensure an acceptable standardization of commercial products.