• Title/Summary/Keyword: severe diarrhea

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A case of Moniezia expensa infection in goat (산양에서 Moniezia expensa 감염증례)

  • Jeong Jae-Myong;Jo Sung-Woo;Kwak Kil-Han;Seo Seok-Yull
    • Korean Journal of Veterinary Service
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    • v.29 no.2
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    • pp.123-128
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    • 2006
  • It's a case of the goat farm reared about 60 heads in Imsil county was outbreak Moniezia expensa infection. And 18 heads of less than 6 month olds goat were died. During the 2005 summer, morbidity and accumulative mortality were more than 60% and 30%, respectively less than 6 month young goat. Most young goat were suffer from diarrhea, severe weight losses, emaciations, and died. In necropsy, there were about 0.7-2.5m of 2-8 adult M expensa in the small intestinal lumen, swollen mesenteric lymph nodes. Slight hemorrhages were seen in lung and moderate hemorrhages were seen in mucous membrane of small intestine. Also various species (Trichostrongylus spp, Haemonchus spp, Eimeria spp) of parasite eggs were seen in fecal test. Pasteurella hemolytica was identified in lung by the API kit (Biomerieux Co. Ltd) for biochemical test. The minimal inhibitory concentration (MIC) results, trimethoprim/sulfamethoxazole, erythromycin, tyrosine, gentamycin, enrofloxacin, and norflocxacin were selected sensitive antibiotics.

Mastitis with Proteus mirabilis in Brittany Spaniel, a case (Brittany Spaniel에서 Proteus mirabilis에 의한 유방염 발생: 증례)

  • Lee, Jeong-Won;Chu, Keum-Suk;Kwak, Kil-Han;Ko, Won-Seuk;Song, Hee-Jong
    • Korean Journal of Veterinary Service
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    • v.32 no.3
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    • pp.215-218
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    • 2009
  • The dog breeding kennel bacterial infection are very significant in perinatal mortality. In many case, Staphylococcus aureus, Streptococcus, and Escherichia coli were infected in intra-uterine or by the genital tract to the puppies, and they are cause of septicemic death of the puppies and clinical mastitis of bitch, leading to septicemic death of newborn puppies. Severe mastitis due to bacterial infection was diagnosed in a 2 year-old female Brittany Spaniel which loss 6 puppies with odor small rice sharp white diarrhea of nine puppies. Bright curd milk and intestinal sample were inoculated on MacConkey agar, blood agar and brain heart infusion agar, and incubated at $37^{\circ}C$ for 24-48 hrs. Gram negative colonies isolated from these sample which were characterized as Glu, Ure, $H_2S$, Orn, Cit, and Cl, and were identified by Microscan Walk-Aways Baxter, American Type Culture Collection, USA) as Proteus mirabils. The isolate was more sensitive to ampicillin, gentamicin, cefoxitin, cefuroxime, and cefazidime. In this results, we confirmed that cause bacteria of septicemic death in puppies was P. mirabilis.

The Preventive Effects of Colon Cancer and Imflammatory Bowel Disease of Supercritical Heat-Treated Radish Extracts

  • Kim, Hyun-Kyoung
    • International Journal of Internet, Broadcasting and Communication
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    • v.12 no.2
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    • pp.98-112
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    • 2020
  • There is a strong connection between the diet rich in antioxidants and the decreased incidence of inflammatory bowel disease and cancerous diseases. Diets that are rich in anti-oxidants particularly include fruits and vegetables containing the high amounts of vitamin A-E, carotenoids, and minerals. The supercritical heat-treated radish extracts of the research result had an inhibitory effect on the development of aberrant crypt foci (ACF), namely, preneoplastic lesions having a potential to become cancer cells and reduced the number of the aberrant crypt foci (ACF) consisting of four or more aberrant crypts (AC) having high risk to become tumors by about half. The supercritical heat-treated radish extracts can reduce the incidence of preneoplastic lesions having a high risk of developing cancer by about 28 %. DSS-treated mice developed symptoms similar to those of human UC, such as severe bloody diarrhea and weight loss. Supercritical heat-treated radish extracts, as well as sulfasalazine, suppressed colonic length and mucosal inflammatory infiltration. In addition, supercritical heat-treated radish extracts treatment significantly reduced the expression of pro-inflammatory signaling molecules through suppression both mitogen-activated protein kinases (MAPK) and nuclear factor-kappa B (NF-kB) signaling pathways, and prevented the apoptosis of colon. Moreover, supercritical heat-treated radish extracts administration significantly led to the up-regulation of anti-oxidant enzyme including SOD and Catalase.

An incidental case of human Heterophyes nocens infection diagnosed by sectional morphology in a biopsy specimen of the small intestine

  • Ryang, Yong-Suk;Lee, Chi-Young;Lee, Kyu-Jae;Lee, Soon-Hyung;Chai, Jong-Yil
    • Parasites, Hosts and Diseases
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    • v.37 no.3
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    • pp.189-194
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    • 1999
  • A case of human infection with Heterophyes nocens (Heterophyidae) was incidentally found in a biopsy specimen of the Meckel's diverticulum at the upper part of the small intestine. The patient was a 58-year-old man living in a rural area of Talsong-gun, Kyongsangbuk-do.He had gastrointestinal symptoms such as epigastric pain, indigestion, and abdominal discomfort for 3 months, and severe diarrhea, abdominal pain, and vomiting for about 1 month before hospitalization. Endoscopy of the upper part of the small intestine revealed a Meckel's diverticulum, and it was excised and histo-pathologically examined. Three adult flukes were incidentally found sectioned in the mucosa, and they were identified as H.nocens. The patient had a history of eating raw mullets at a fish market in Pusan 6 months ago, and the mullets were presumed to be the source of infection. This case brings a considerable interest in that specific diagnosis of heterophyid infections could be done by sectional morphology of the worms.

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Experience for S-OIV of Admission Pediatric Patient with S-OIV at YUMC, 2009 (2009년 신종 인플루엔자로 영남대학교 의료원에 입원한 환아의 실태 조사)

  • Sung, Myong-Soon;Choi, Kwang-Hae
    • Journal of Yeungnam Medical Science
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    • v.27 no.1
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    • pp.18-26
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    • 2010
  • The clinical picture in severe cases of pandemic (H1N1) 2009 influenza is markedly different from the disease pattern seen during the epidemics of seasonal influenza as many of those affected were previously healthy young people. Current predictions estimate that during a pandemic wave, 12~30% of the population will develop clinical influenza (compared with 5~15% for seasonal influenza) with 4% of those patients requiring hospital admissions and one in five requiring critical care. Until July 6, 94,512 people have been infected in 122 countries, of whom 429 have died with an overall case-fatality rate of <0.5%. Most of the confirmed cases of S-OIV (Swine-Origin Influenza A Virus) infection have been characterized by a self-limited, uncomplicated febrile respiratory illness and 38% of the cases have also included vomiting or diarrhea. Efforts to control these outbreaks are based on our understanding of novel S-OIV (Swine-Origin Influenza A Virus) and the previous influenza pandemics. So, this review covers the experience with S-OIV (Swine-Origin Influenza A Virus) for the admission and background data and the clinical presentation, diagnosis and treatment of H1N1 in pediatric patient with S-OIV (Swine-Origin Influenza A Virus) at YUMC, 2009.

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A PREDICTION OF BODY WATER COMPARTMENTS OF GROWING CATTLE IN VIVO

  • Sekine, J.;Fujita, K.;Asahida, Y.
    • Asian-Australasian Journal of Animal Sciences
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    • v.5 no.1
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    • pp.7-11
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    • 1992
  • Body water compartments in vivo were determined in Holstein cattle with age ranging from 5 to 521 days to obtain an equation to estimate volumes of body water. Live weight ranged from 47 to 480 kg. Compartments were determined as antipyrine space for total body water (TBW), thiocyanate space for extracellular water (ECW) and Evans blue dye space for plasma water (PW). Body water compartments expressed as a percentage of live weight decreased as age in days increased and significantly correlated with age in days. Regression analyses revealed that prediction equations had low accuracy. Regression equations of body water compartments on live weight (WT, kg) were useful for the prediction of body fluid with a high accuracy. Live weight significantly regressed on age in days (Day), which was inferred to be utilized for estimation of standardized live weight in case animals were emaciated by certain causes such as severe diarrhea or dehydration. In conclusion, following equations were presented to estimate body water compartments of cattle in vivo : TBW in liters = $0.556({\pm}0.007)WT+10$, r = 0.993, $SE{\pm}0.7$ ECW in liters = $0.321({\pm}0.008)WT+10$, r = 0.978, $SE{\pm}0.8$ PW in liters = $0.0502({\pm}0.0012)WT+1.6$, r = 0.0983, $SE{\pm}0.1$ WT (kg) = $0.772({\pm}0.018)Day+24$, r = 0.982, $SE{\pm}2.3$.

Feline Panleukopenia Virus Infection in a Siberian Tiger (Panthera tigris altaica) (시베리아 호랑이에서의 고양이범백혈구감소증)

  • Jung, Iruo;Kim, Yeong-Sub;Jee, Hyang;Sohn, Suh-Young;Yoo, Han-Sang;Kim, Dae-Yong;Youn, Hwa-Young;Shin, Nam-Shik
    • Journal of Veterinary Clinics
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    • v.26 no.5
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    • pp.504-507
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    • 2009
  • An 1-year old male siberian tiger showing severe vomiting and blackish and frothy diarrhea for 3 days were dead in Seoul Zoo. Gross finding at necropsy were small amount of blood were found in abdominal cavity and intestine. In small and large intestine, there were necrosis and detachment epithelial cell of intestinal mucosa in histopathology. The presence of feline panleukopenia virus (FPV) antigen was detected by PCR. In microbiology, E.coli and Enterococcus faecalis were isolated from the stool. This case was diagnosed in death induced by FPV infection according to CBC, histopathology and PCR.

Comparison of Single-Dose Toxicity by Intravenous Infusion or Bolus Injection with CKD-602, a Camptothecin Anticancer Agent in Rats (I): Toxic Effects with regard to Mortality and Clinical Signs

  • Kim, Choong-Yong;Han, Junghee;Yang, Byung-Chul;Kim, Joon-Kyum;Kim, Jong-Choon;Ha, Chang-Su;Han, Sang-Seop
    • Toxicological Research
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    • v.20 no.4
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    • pp.375-380
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    • 2004
  • The toxicity of CKD-602 was investigated at doses of 0, 3, 9, and 27 mg/kg in rats, by administering the same total dose over 24-hr continuous infusion or bolus injection. CKD-602 treatment caused gastrointestinal symptoms such as diarrhea, soft stool, and soiled perineal region. It also decreased body weight at doses of 9 and 27 mg/kg in a dose-dependant manner. At 3 mg/ kg, clinical signs and body weight decrease were more severe in the infusion group than in the bolus group. In the bolus group, mortalities were 0/8, 0/8, 1/8, and 3/8 at 0, 3, 9, and 27 mg/kg, respectively, whereas those were 0/8, 1/8, 8/8, and 8/8 in the infusion group. $LD_{50}$ values were 36.25 mg/kg for bolus and 3.50 mg/kg for infusion, respectively. This finding indicates that the toxic potency of CKD-602 by continuous infusion is about 10 times higher than by bolus injection. Our findings suggest that the toxic effects of CKD-602 are dependant upon the duration of intravenous administration.

Identification of Salmonella spp. from porcine salmonellosis by matrix-assisted laser desorption ionization-time of flight mass spectrometry

  • Yang, Hyoung-Seok;Kim, Jae-Hoon
    • Korean Journal of Veterinary Service
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    • v.41 no.2
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    • pp.105-110
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    • 2018
  • A total of 41 Salmonella (S.) strains were isolated from pigs suffered with severe watery diarrhea and were tried to identify by both matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) and polymerase chain reaction (PCR) analysis. Fibrinous exudate and ulceration in the large intestine were prevalent in gross observation, and variable degrees of enteritis were observed in the histology of large intestines. Subsequent polymerase chain reaction (PCR) analyses demonstrated that 41 strains were identified as S. Typhimurium (39 strains), though 2 stains were failed to identify. Further identification was performed using both direct smear and protein extraction method by MALDI-TOF MS analyses. In terms of extraction methods, 100% (41/41) of isolates were identified to species level of S. spp. Whereas only 43.9% (18/41) were identified to species level using the direct method. These results thus suggest that rapid and accurate diagnosis of porcine salmonellosis can be guaranteed by MALDI-TOF MS combined with protein extraction method.

A Case Report of Irritable Bowel Syndrome Treated with Daechilgitang-gagambang (과민성대장증후군 환자의 대칠기탕가감방(大七氣湯加減方) 임상보고)

  • Lee, Ju-Il;Park, Young-Chul;Kwon, Do-Ik;Sun, The-Cheng;Kim, Ju-Young;Park, Jun-Ha;Hong, Eun-Ki
    • The Journal of Korean Obstetrics and Gynecology
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    • v.20 no.1
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    • pp.268-276
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    • 2007
  • Purpose : The purpose of this study is to report the effect of oriental treatments for Irritable Bowel Syndrome. Methods : We treated a 57 - year - old female who had severe abdominal pain and discomfort companied by alteration in bowel function, a combination of diarrhea and constipation, with Herb medication ( Daechilgitang-gagambang )and acupuncture therapy at the same time. Results : After oriental medical treatment, the clinical symptom of Irritable Bowel Syndrome was improved. Conclusion : This case study shows that the oriental medical therapy is effective in treating irritable bowel syndrome. So that, it is helpful in decreasing the symptoms of patients and in improving quality of life.

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