• Journal of Life Science
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• v.9 no.2
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• pp.194-200
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• 1999

Grinding aid is a necessary unit operation when the raw materials are handled in solid form, and the purpose is to improve the bioavailability by reducing the particle size. For the particle design of pefloxacin, the dry planetary ball-mill was used. With the drying process, 330 g of zirconia ball with its size of 2 mm in diameter and 10 g of pefloxacin were transferred to the pot and mixed well. The mixture was ground at 112 rpm (60 Hz) for 15, 30, and 60 min, respectively. The most satisfactory grinding products were generated at 15 min of grinding time for their particle size. The volume mean diameter $\X_50$ of the grinding products was 2.97 $\mu$m. X-ray diffraction (XRD), differential scanning calorimeter (DSC), and infrared spectroscopy (IR) patterns were relatively unchanged before pulverizing pefloxacin and in the progress of grinding. Thus, these results suggest that this pulverizing method can be used for grinding products without evident effect on stability of the drug pefloxacin. Dissolution test was carried out to set up the optimal detective condition against residual antibacteria of fish by HPLC. The grinding pefloxacin for 15 min is most effective in dissolution test.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.3
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• pp.197-208
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• 2016

The study showed that directional Shared Leadership and transformational Shared Leadership positively influences the relationship between Shared Leadership and interpersonal relationships in the view of organizational wellbeing. In addition, in the relationship between Shared Leadership and rewarding job experience of organizational wellbeing, three leadership types excluding directional Shared Leadership had positive effects. In addition, transformational Shared Leadership and empowering Shared Leadership had a positive impact on the relationship between Shared Leadership and organizational mood of organizational wellbeing. In the relationship between Shared Leadership and a sense of fulfillment in the view of organizational wellbeing, transformational Shared Leadership only had a positive effect. As is the case with the sense of fulfillment, the transformational Shared Leadership, of and itself, positively influenced the relationship between Shared Leadership and leisure of life of organizational wellbeing. A analysis of the study showed that transformational Shared Leadership has an impact on both organizational wellbeing and personal wellbeing. Transformational Shared Leadership helps set up mutual vision or strategies, or to challenge each other to enhance existing processes and procedures. On the other hand, directional Shared Leadership influences the interpersonal relations only, whereas transactional Shared Leadership impacts rewarding job experience only. Presenting clearer ideas on what to do to each other and sharing the reward for performance implies that the members of an organization can feel much more rewarded through job engagement.

• The Journal of the Korea Contents Association
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• v.14 no.5
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• pp.156-165
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• 2014

In this study, the effect of communication with a guardian of a recipient of a Long-term Care Program on job satisfaction of care helpers of in-home care facilities for the elderly is analyzed. First, most of the care helpers are content with their job despite low pay and short work-hour. Especially, they are aware of the need of communication with a guardian but skeptical about the need of having intimacy with a guardian, so the relation between a care helper and a guardian is usually formal only. Second, in terms of characteristics of a guardian, care helpers have higher job satisfaction when a guardian is a male and old, and does not have an unreasonable demand. Third, they have higher job satisfaction when they have better communicate with a guardian rather than higher intimacy. Considering this result, we should make programs such as education for a guardian to develop intimacy with a care helper and one for a care helper to develop intimacy and communicate effectively with a guardian. It is also needed to have guidelines which set up relationship between a helper and a guardian.

• Journal of Bio-Environment Control
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• v.23 no.3
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• pp.199-204
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• 2014

This study evaluated the effect of water content in the substrate during pre- and post-grafting period on the survival rate and quality of tomato plug seedlings. Nine combinations of three water levels (high, medium, and low) were set up in the substrate of both scion and rootstock. The water content in the substrate of the scion did not affect the survival rate of grafted tomato seedlings, while the survival rate was statically different among the various water contents in the substrate of the rootstock. The maximum survival rates (100%) were observed in seedlings treated with high water levels in the substrate of the rootstock, and the survival rates declined with decreasing water content in the rootstock substrate. The growth characteristics were not significantly affected by different water content in the scion substrate, while they were statically different among the seedlings treated with various water contents in the rootstock substrate. The growth characteristics decreased with decreasing water content in the rootstock substrate. The highest value of compactness was observed in grafted seedlings, which combined medium water level in the scion and high water level in the rootstock substrate treatment. The root morphology of tomato seedlings was also affected by water content in the rootstock substrate. The total root surface area, total root length, and number of root tips decreased with deceasing water content in the rootstock substrate.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.8
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• pp.474-481
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• 2018

The purpose of this study was to examine the mediating effects of maternal family experience on the relationship between mothers' tendency to addicted to smartphones and the social competence of young children. The subjects of this study were 481 mothers who delivered infants to a kindergarten or daycare center in Jeju area After conducting the questionnaire, the results of the responses were analyzed. To analyze the collected data, structural equations were implemented using SPSS Statistic 18.0 program. The results of this study are summarized as follows. First, the correlational analysis showed that the tendency of the addiction of smartphone and the social ability of the infant showed a significant correlation with the mother's family experience. Second, in the relationship between the mother's smartphone tendency and the social competence of the infant, The research model and the competition model were set up to examine the mediating effect and the competition model was found to be more appropriate. As a result, it can be seen that mother's original family experience is partly mediated in relation to mother's tendency to add to smartphone and social competence of infant. Based on these results, the implications of this study and suggestions for subsequent research were discussed.

• Journal of the Korean Applied Science and Technology
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• v.36 no.4
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• pp.1128-1135
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• 2019

In this study, different types of polyether amines and H₁₂MDI were used to synthesize water dispersed urea resins, which can be applied to coating material on the concrete slabs for bicycle road using the ordinary application equipments. The concentrations of several polyether amines with different molecular weights and the number of amine functionality were varied to set up the optimal condition for water dispersed urea resin preparation with both an excellent tensile strength and an elongation. In addition, the effect of DMPA[2,2-Bis(hydroxymethyl)propanoic acid] concentration on the storage stability of the water dispersed urea resin was also investigated. The formation of urea bonds from isocyanate and polyether amines was confirmed through FT-IR ATR spectroscopy. From the mechanical properties of urea resins, PU-4 and PU-6, which were prepared with both diamines and triamine of different molecular weights and number of functionality, showed the tensile strength of 10.5 N/㎟ and 12.7 N/㎟, respectively and the elongation of 1165 % and 969%, respectively. Among the water dispersed urea resin synthesized with different contents of DMPA, PU-6 showed the highest mechanical properties, a tensile strength of 14.2 N/㎟ and an elongation of 993%. In addition, the water dispersion state of this PU-6 was the most stable even after 8 weeks.

• Journal of Korea Water Resources Association
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• v.43 no.10
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• pp.865-881
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• 2010

To evaluate influence of the future climate change on water environment, it is necessary to use a rainfall-runoff model, or a basin model allowing us to simultaneously simulate water quality factors such as sediment and nutrient material. Thus, SWAT is selected as a watershed-based model and Nakdong river basin is chosen as a target basin for this study. To apply climate change scenarios as input data to SWAT, Australian model (CSIRO: Mk3.0, CSMK) and Canadian models (CCCma: CGCM3-T47, CT47) of GCMs are used. Each GCMs which have A2, B1, and A1B scenarios effectively represent the climate characteristics of the Korean peninsula. For detecting climate change in Nakdong river basin, precipitation and temperature, increasing rate of these were analyzed in each scenarios. By simulation results, flow and increasing rate of these were analyzed at particular points which are important in the object basin. Flow and variation of flow in the scenarios for present and future climate changes were compared and analyzed by years, seasons, divided into mid terms. In most of the points temperature and flow rate are increased, because climate change is expected to have a significant effect on rising water temperature and flow rate of river and lake, further on the basis of this study result should set enhancing up water control project of hydraulic structures caused by increasing outer discharge of the Nakdong River Basin due to climate change.

• Journal of Acupuncture Research
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• v.15 no.2
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• pp.147-155
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• 1998

Acupuncture and Radix Astragali aqua-acupuncture stimuli have long been used to cure human diseases. However, it still remains to be unkown on its action mechanism, physiolosical and biochemical aspects. Thus, many attempts were made to show the scientific background covering the above mentioned mechanisms. Most recent studies show that these tests improve blood circulatory system and increase leucocyte counts. In this study, we have applied the acupuncture stimuli to mouse Sinsu(BL-23), which is a stimulative point of oriental medicine, to see if cytokine such as IL-6 can be detected. Mice were treated with lipopolysaccharide(LPS) for inflammation induction, and then reverse transcriptase-polymerase chain reaction (RT-PCR) using each primer set was performed to trace the amounts of mRNA. The results are summarized as follows ; 1. IL-6 was not temporarily expressed in normal mice 15 min after the acupuncture was pulled out. But, it started to show a feeble expression at 30 min after the removal of acupuncture and it started to reduce at 1h. after the acupuncture was pulled out 2. IL-6 was specifically expressed in LPS-treated mouse 30 min after the acupuncture was pulled out. The transcriptional expressions of LPS-treated mice were more effective than those of normal mice at 30 min after the removal of acupuncture 3. IL-6 was not temporarily expressed in normal mice 15 min after Radix Astragali aqua-acupuncture. But it expressed most highly at 30 min, and the transcriptional expressions of IL-6 was continued to 3 h. 4. IL-6 was not expressed in all the time after Radix Astragali aqua-acupuncture in LPS-treated mice. Therefore, a follow-up of cytokine IL-6 can be used not only a basis of the effect of acupuncture and Radix Astragali aqua-acupuncture but a diagnosis giude through the immunological action of thats. And, it is suggested that cytokine's expression by Acupuncture and Radix Astragali aqua-acupuncture stimulation should be continuously elucidated.

• Management & Information Systems Review
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• v.37 no.1
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• pp.19-40
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• 2018

The purpose of this study is to analyze the effects of a firm's dynamic capabilities measured by sensing, seizing, transforming, coordinating, and learning capabilities on its competitive capabilities, such as product quality, process flexibility, delivery speed, and low cost. The relationship among dynamic capabilities, competitive capabilities, and export firm performance is set up as a research model based on empirical studies related to the existing dynamic capability perspective and competitive capabilities. To test this research model, this study collected 102 samples of data using a questionnaire survey on both manufacturing and exporting firms. The partial least squares method is used and the following results are derived from an empirical analysis. First, dynamic capabilities have a positive effect on competitive capabilities, such as product quality, process flexibility, delivery speed, and low cost. Second, product quality and process flexibility have a positive effect on export firm performance. Third, unlike previous research results, this study finds that the competitive capabilities of a firm in the areas of delivery speed and low cost do not significantly affect its performance. These findings provide meaningful implications for export venture firms that need to acquire and maintain competitive advantage in a rapidly changing environment.

• Journal of the Korea Convergence Society
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• v.8 no.11
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• pp.241-247
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• 2017

The purpose of this study was to determine the satisfaction and return impact of the Festival visitors visiting the food and art festivals in Suncheon city. which successfully hosted the Suncheon Bay Garden Expo.. In order to carry out this research, hypothesis was set up, and after the questionnaire survey was conducted for the visitors participating in the festival, empirical analysis was conducted through the survey. Also, I would like to present the implications for the tourism development process and the convergence research of the fourth industry for the garden and food tourism of the tourists coming back again in the future due to the festival. The effect of factors on festival satisfaction was found to be influential in order of tourism product, food, guide and public event program. Also products and food facilities. It was confirmed that the guide and publicity part had an influence on the revisit of the festival and also the recommendation of the festival. As a result, the attributes of satisfaction factor of Suncheon Food & Art Festival were confirmed and causality was derived because visitors' satisfaction had positive influence on behavior intention. However, the limitations of the study remain in that it does not reveal the subdivision factors of the satisfaction and perceived satisfaction in measuring the festival satisfaction.