• Archives of Craniofacial Surgery
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• v.23 no.6
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• pp.256-261
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• 2022

Background: Treating panfacial fractures (PFFs) can be extremely difficult even for experienced surgeons. Although several authors have attempted to systemize the surgical approach, performing surgery by applying a unidirectional sequence is much more difficult in practice. The purpose of this study was to review the literature on PFF surgery sequence and to understand how different surgical specialists-plastic reconstructive surgery (PRS) and oral maxillofacial surgery (OMS)-chose sequence and review PFFs fixation sequence in clinical cases. Methods: The PubMed and Google Scholar databases were scoured for publications published up until May 2020. Data extracted from the studies using standard templates included fracture part, fixation sequence, originating specialist, and the countries. Bibliographic details like author and year of publication were also extracted. Also, we reviewed the data for PFFs patients in the Trauma Registry System of Dankook University Hospital from 2011 to 2021. Results: In total, 240 articles were identified. This study comprised 22 studies after screening and full-text analysis. Sixteen studies (12 OMS specialists and 4 PRS specialists) used a "bottom-top" approach, whereas three studies (1 OMS specialist and 2 PRS specialists) used a "top-bottom" method. However, three studies (only OMS specialists) reported on both sequences. In our hospital, there were a total of 124 patients with PFF who were treated during 2011 to 2021; 64 (51.6%) were in upper-middle parts, 52 (41.9%) were in mid-lower parts, and eight (6.5%) were in three parts. Conclusion: Bottom-top sequencing was mainly used in OMS specialists, and top-bottom sequencing was used at a similar rate by two specialists in literature review. In our experience, however, it was hard to consistently implement unidirectional sequence suggested by a literature review. We realigned the reliable and stable buttresses first with tailoring individually for each patient, rather than proceeding in the unidirectional sequence like bottom-top or top-bottom.

• The KIPS Transactions:PartD
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• v.11D no.4
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• pp.845-854
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• 2004

Motif databases are used in the function and structure prediction of proteins. The frequency of use about these databases increases continuously because of protein sequence data growth. Recently, many researches about motif resource integration are proceeding. However, existing motif databases were developed independently, thus these databases have a heterogeneous search result problem. Database intnegration for this problem resolution has a periodic update problem, a complex query process problem, a duplicate database entry handling problem and BML support problem. Therefore, in this paper, we suppose a database resource integration method for these problem resolution, describe periodically integrated database update method and XML transformation. finally, we estimate the implementation of our prototype and a case database.

• Journal of the Korean Institute of Telematics and Electronics B
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• v.32B no.5
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• pp.671-682
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• 1995

In this paper, we propose a multimedia query language MQL which defines and manipulates multimedia data as integration of monomedia data in time and space. The MQL is designed for a multimedia data model, called the object-relationship model, and based on the multimedia object calculus which formally describes operations on multimedia data. The SQL- like syntax for class definition and object manipulation, such as retrieval, insert, update, and delete, is defined. We show how the MQL can represent the user queries using composite temporal-spatial class structures and various relationships, such as equivalence and sequence.

• Proceedings of the Korean Information Science Society Conference
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• 2001.04b
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• pp.202-204
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• 2001

본 논문에서는 대형 시퀀스 데이터베이스에서 타임 워핑을 지원하는 유사 검색을 효과적으로 처리하는 방안에 관하여 논의한다. 타임 워핑은 시퀀스의 길이가 서로 다른 경우에도 유사한 패턴을 갖는 시퀀스들을 찾을 수 있도록 해 주는 변환이다. 타임 워핑 거리는 삼각형 부등식 성질을 만족하지 못하므로 기존의 기법들은 착오 기각 없이 다차원 인덱스를 사용할 수 없었다. 본 논문에서는 타임 워핑을 지원하는 새로운 인덱스 기반 유사 검색 기법을 제안한다. 제안된 주요 목표는 착오 기각 없이 대형 데이터베이스에서도 좋은 검색 성능을 보장하는 것이다. 다양한 실험을 통하여 제안된 기법의 우수성을 규명한다. 실험 결과에 의하면, 제안된 기법은 기존의 기법과 비교하여 약 4배에서 43배까지의 성능 개선 효과를 가지는 것을 나타났다.

• Journal of Microbiology and Biotechnology
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• v.17 no.3
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• pp.408-413
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• 2007

Putrescine has a negative effect on health and is also used as an indicator of quality on meat products. We investigated the genes involved in putrescine production by Serratia liquefaciens IFI65 isolated from a spoiled Spanish dry-cured ham. We report here the genetic organization of its ornithine decarboxylase encoding region. The 5,506-bp DNA region showed the presence of three complete and two partial open reading frames. Putative functions have been assigned to several gene products by sequence comparison with proteins included in the databases. The second gene putatively coded for an ornithine decarboxylase. The functionality of this decarboxylase has been experimentally demonstrated by complementation to an E. coli defective mutant. Based on sequence comparisons of some enterobacterial ornithine decarboxylase regions, we have elaborated a hypothetical pathway for the acquisition of putrescine biosynthetic genes in some Enterobacteriaceae strains.

• Journal of Industrial Technology
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• v.21 no.A
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• pp.155-166
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• 2001

This paper deals with the subsequence searching problem under time-warping. Our work is motivated by the observation that subsequence searches slow down quadratically as the average length of data sequences increases. To resolve this problem, the Segment-Based Approach for Subsequence Searches (SBASS) is proposed. The SBASS divides data and query sequences into a series of segments, and retrieves all data subsequences. Our segmentation scheme allows segments to have different lengths; thus we employ the time warping distance as a similarity measure for each segment pair. For efficient retrieval of similar subsequences, we extract feature vectors from all data segments exploiting their monotonically changing properties, and build a spatial index using feature vectors. The effectiveness of our approach is verified through extensive experiments.

• The KIPS Transactions:PartD
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• v.10D no.2
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• pp.261-266
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• 2003

A protein, which is a linear polymer of amino acids, is one of the most important bio-molecules composing biological structures and regulating bio-chemical reactions. Since the characteristics and functions of proteins are determined by their amino acid sequences in principle, protein sequence determination is the starting point of protein function study. This paper proposes a protein sequence prediction method based on data mining techniques, which can overcome the limitation of previous bio-chemical sequencing methods. After applying multiple proteases to acquire overlapped protein fragments, we can identify candidate fragment sequences by comparing fragment mass values with peptide databases. We propose a method to construct multi-partite graph and search maximal paths to determine the protein sequence by assembling proper candidate sequences. In addition, experimental results based on the SWISS-PROT database showing the validity of the proposed method is presented.

• Journal of KIISE:Databases
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• v.36 no.3
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• pp.169-179
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• 2009

Communication log data consist of communication events such as sending and receiving e-mail or instance message and visiting web sites, etc. Many countries including USA and EU enforce the retention of these data on the communication service providers for the purpose of investigating or detecting criminals through the Internet. Because size of the retained data is very large, the efficient method for extracting valuable information from the data is needed for Law Enforcement Authorities to use the retained data. This paper defines the Interactive Communication Sequence Patterns(ICSPs) that is the important information when each communication event in communication log data consists of sender, receiver, and timestamp of this event. We also define a Mining(FDICSP) problem to discover such patterns and propose a method called Fast Discovering Interactive Communication Sequence Pattern(FDICSP) to solve this problem. FDICSP focuses on the characteristics of ICS to reduce the search space when it finds longer sequences by using shorter sequences. Thus, FDICSP can find Interactive Communication Sequence Patterns efficiently.

• Parasites, Hosts and Diseases
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• v.39 no.2
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• pp.151-160
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• 2001

Randomly selected 435 clones from Acanthamoeba healyi cDNA library were sequenced and a total of 387 expressed sequence tags (ESTs) had been generated. Based on the results of BLAST search, 130 clones (34.4%) were identified as the genes enconding surface Proteins , enzymes for DNA, energy Production or other metabolism, kinases and phosphatases, protease, proteins for signal transduction, structural and cytoskeletal proteins, cell cycle related proteins, transcription factors, transcription and translational machineries, and transporter proteins. Most of the genes (88.5%) are newly identified in the genus Acanthamoeba. Although 15 clones matched the genes of Acanthamoeba located in the public databases, twelve clones were actin gene which was the most frequently expressed gene in this study. These ESTs of Acanthamoeba would give valuable information to study the organism as a model system for biological investigations such as cytoskeleton or cell movement, signal transduction, transcriptional and translational regulations. These results would also provide clues to elucidate factors for pathogenesis in human granulomatous amoebic encephalitis or keratitis by Acanthamoeba.

• Environmental Analysis Health and Toxicology
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• v.24 no.2
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• pp.107-117
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• 2009

Metal pollution of aquatic ecosystems is a problem of economic and health importance. Information regarding molecular responses to metal exposure is sorely needed in order to identify potential biomarkers. To determine the effects of heavy metals on chironomids, the full-length cDNA of alcohol dehydrogenase (ADH3) from Chironomus riparius was determined through molecular cloning and rapid amplification of cDNA ends (RACE). The expression of ADH3 was analyzed under various cadmium and copper concentrations. A comparative and phylogenetic study among different orders of insects and vertebrates was carried out through analysis of sequence databases. The complete cDNA sequence of the ADH3 gene was 1134 bp in length. The sequence of C. riparius ADH3 shows a low degree of amino acid identity (around 70%) with homologous sequences in other insects. After exposure of C. riparius to various concentrations of copper, ADH3 gene expression significantly decreased within 1 hour. The ADH3 gene expression was also suppressed in C. riparius after cadmium exposure for 24 hour. However, the effect of cadmium on ADH3 gene expression was transient in C. riparius. The results show that the suppression of ADH3 gene by copper exposure could be used as a possible biomarker in aquatic environmental monitoring and imply differential toxicity to copper and cadmium in C. riparius larvae.